Isolated noncompaction of the ventricular myocardium: Ultrafast computed tomography and magnetic resonance imaging View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2001-08

AUTHORS

Yuji Hamamichi, Fukiko Ichida, Ikuo Hashimoto, Keiichi Hirono Kei-ichiro Uese, Toshio Miyawaki, Shinya Tsukano, Yasuo Ono, Shigeyuki Echigo, Tetsuro Kamiya

ABSTRACT

This study was undertaken to evaluate the feasibility of ultrafast computed tomography (CT) and magnetic resonance imaging (MRI) for anatomical and pathophysiological diagnosis of isolated noncompaction of the left ventricular myocardium (INVM) compared with other imaging modalities including thallium myocardial imaging. Six patients, three sets of siblings, ranging in age from 13 to 18 years, were included in this study. Two-dimensional echocardiograms revealed numerous prominent trabeculations and deep intertrabecular recesses in one or more ventricular wall segments in all cases. Thallium-201 myocardial imaging disclosed a hypoperfusion area corresponding to the zones where noncompacted ventricular myocardium was localized. Ultrafast CT showed early defects of varying degrees and rate enhancement of the noncompacted ventricular myocardium, implying fibrosis in this area. MRI disclosed inner zones of noncompacted myocardium distinguishable from thin outer zones of compacted myocardium. T2-weighted imaging revealed high intensity areas at the apex of the left ventricle, suggesting disturbed microcirculation due to fibrosis, thrombus formation, and hypokinesis. Cine MRI revealed hypokinesis of the noncompacted ventricular wall during the cardiac cycle. In conclusion, ultrafast CT and MRI provide high-resolution imaging of noncompacted myocardium, and also pathophysiological details regarding this rare disease. More... »

PAGES

305-314

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1023/a:1011658926555

DOI

http://dx.doi.org/10.1023/a:1011658926555

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1042978950

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/11599870


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