Effect of Ischemia–Reperfusion on Bile Canalicular F-Actin Microfilaments in Hepatocytes of Human Liver Allograft View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2001-08

AUTHORS

Liliane Benkoël, Frank Dodero, Jean Hardwigsen, Pierre Campan, Danielle Botta-Fridlund, Dominique Lombardo, Yves Patrice Le Treut, Albert Chamlian

ABSTRACT

We studied and quantified the effect of ischemia-reperfusion on hepatic F-actin on bile canalicular and basolateral membranes in human liver allografts by means of confocal laser scanning microscopy imaging. The phalloidin-FITC staining of F-actin was normal in liver hepatocytes before reperfusion but decreased significantly after reperfusion (by 25% of controls). These results indicate that hepatic F-actin alteration is produced during the reperfusion phase. This modification, probably induced by reactive oxygen species, could impair bile canalicular contraction and tight junction permeability and consequently bile secretion in the postoperative period. More... »

PAGES

1663-1667

Identifiers

URI

http://scigraph.springernature.com/pub.10.1023/a:1010693218680

DOI

http://dx.doi.org/10.1023/a:1010693218680

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1039029411

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/11508665


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Actin Cytoskeleton", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Actins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Bile Canaliculi", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Biopsy", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cell Membrane", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Coloring Agents", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Fluorescein-5-isothiocyanate", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hepatocytes", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Liver Transplantation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Microscopy, Confocal", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Phalloidine", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Reperfusion Injury", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "name": [
            "Laboratoire de Pathologie Cellulaire et M\u00e9tabolique du Foie, INSERM U 559, Facult\u00e9 de M\u00e9decine, 27 boulevard Jean Moulin, 13385, Marseille Cedex 05, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Benko\u00ebl", 
        "givenName": "Liliane", 
        "id": "sg:person.072273167.74", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.072273167.74"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Laboratoire de Pathologie Cellulaire et M\u00e9tabolique du Foie, INSERM U 559, Facult\u00e9 de M\u00e9decine, 27 boulevard Jean Moulin, 13385, Marseille Cedex 05, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Dodero", 
        "givenName": "Frank", 
        "id": "sg:person.01114620434.35", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01114620434.35"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "H\u00f4pital de la Conception", 
          "id": "https://www.grid.ac/institutes/grid.411535.7", 
          "name": [
            "Unit\u00e9 de Transplantation H\u00e9patique, H\u00f4pital de la Conception, 147 bd. Baille, 13385, Marseille Cedex 05, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hardwigsen", 
        "givenName": "Jean", 
        "id": "sg:person.0575737550.25", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0575737550.25"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "H\u00f4pital de la Conception", 
          "id": "https://www.grid.ac/institutes/grid.411535.7", 
          "name": [
            "Unit\u00e9 de Transplantation H\u00e9patique, H\u00f4pital de la Conception, 147 bd. Baille, 13385, Marseille Cedex 05, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Campan", 
        "givenName": "Pierre", 
        "id": "sg:person.01323057072.43", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01323057072.43"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "H\u00f4pital de la Conception", 
          "id": "https://www.grid.ac/institutes/grid.411535.7", 
          "name": [
            "Service d'H\u00e9pato-Gastroent\u00e9rologie, H\u00f4pital de la Conception, 147 bd. Baille, 13385, Marseille Cedex 05, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Botta-Fridlund", 
        "givenName": "Danielle", 
        "id": "sg:person.01012356705.38", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01012356705.38"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Laboratoire de Pathologie Cellulaire et M\u00e9tabolique du Foie, INSERM U 559, Facult\u00e9 de M\u00e9decine, 27 boulevard Jean Moulin, 13385, Marseille Cedex 05, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lombardo", 
        "givenName": "Dominique", 
        "id": "sg:person.01167131513.20", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01167131513.20"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "H\u00f4pital de la Conception", 
          "id": "https://www.grid.ac/institutes/grid.411535.7", 
          "name": [
            "Unit\u00e9 de Transplantation H\u00e9patique, H\u00f4pital de la Conception, 147 bd. Baille, 13385, Marseille Cedex 05, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Le Treut", 
        "givenName": "Yves Patrice", 
        "id": "sg:person.01115256103.65", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01115256103.65"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "H\u00f4pital de la Conception", 
          "id": "https://www.grid.ac/institutes/grid.411535.7", 
          "name": [
            "Unit\u00e9 de Transplantation H\u00e9patique, H\u00f4pital de la Conception, 147 bd. Baille, 13385, Marseille Cedex 05, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chamlian", 
        "givenName": "Albert", 
        "id": "sg:person.01012357464.43", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01012357464.43"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/s0009-8981(99)00138-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000985075"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bst0280136", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001675782"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bst0280136", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001675782"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1440-1681.1995.tb01992.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002741562"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1139/o95-071", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013232408"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0041-1345(98)01222-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016714659"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1023/a:1026683531461", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023659560", 
          "https://doi.org/10.1023/a:1026683531461"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/abbi.1996.9847", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024017127"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.271.43.26863", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024230779"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0925-4439(96)00031-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024629909"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s004670050385", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025663804", 
          "https://doi.org/10.1007/s004670050385"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/hep.510260215", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026461614"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0891-5849(96)00571-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027651916"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1172/jci116223", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028592002"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0006-2952(94)90124-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028685064"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0006-2952(94)90124-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028685064"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0024-3205(99)00668-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028852422"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ki.1992.366", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031647035", 
          "https://doi.org/10.1038/ki.1992.366"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/hep.510240512", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037669242"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00197554", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039123967", 
          "https://doi.org/10.1007/bf00197554"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00197554", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039123967", 
          "https://doi.org/10.1007/bf00197554"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/jsre.1996.0310", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040630053"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/hep.1840210433", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041479281"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0925-4439(99)00114-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046169805"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/hep.510300130", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049068907"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.76.9.4498", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050098152"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1023/a:1005533531756", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053271734", 
          "https://doi.org/10.1023/a:1005533531756"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/ajprenal.1999.276.4.f544", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1074356309"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074587490", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1076450987", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078589252", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/ajpgi.1994.267.4.g630", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1082576623"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083108687", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083116126", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083322928", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083369890", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2001-08", 
    "datePublishedReg": "2001-08-01", 
    "description": "We studied and quantified the effect of ischemia-reperfusion on hepatic F-actin on bile canalicular and basolateral membranes in human liver allografts by means of confocal laser scanning microscopy imaging. The phalloidin-FITC staining of F-actin was normal in liver hepatocytes before reperfusion but decreased significantly after reperfusion (by 25% of controls). These results indicate that hepatic F-actin alteration is produced during the reperfusion phase. This modification, probably induced by reactive oxygen species, could impair bile canalicular contraction and tight junction permeability and consequently bile secretion in the postoperative period.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1023/a:1010693218680", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1018525", 
        "issn": [
          "0163-2116", 
          "1573-2568"
        ], 
        "name": "Digestive Diseases and Sciences", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "8", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "46"
      }
    ], 
    "name": "Effect of Ischemia\u2013Reperfusion on Bile Canalicular F-Actin Microfilaments in Hepatocytes of Human Liver Allograft", 
    "pagination": "1663-1667", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "b9ea63ae30f14ce768e7b76070b163d111359d45268f2a61a7deafabb93e2383"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "11508665"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "7902782"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1023/a:1010693218680"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1039029411"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1023/a:1010693218680", 
      "https://app.dimensions.ai/details/publication/pub.1039029411"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T19:54", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8681_00000500.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1023/A:1010693218680"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1023/a:1010693218680'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1023/a:1010693218680'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1023/a:1010693218680'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1023/a:1010693218680'


 

This table displays all metadata directly associated to this object as RDF triples.

274 TRIPLES      21 PREDICATES      75 URIs      34 LITERALS      22 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1023/a:1010693218680 schema:about N21b715735ad24f259bd5fcb36e6da383
2 N32a91f9737494b278a23ff4ac17e841c
3 N3d35ddb832ad4046a546fa8438fa5fee
4 N4962d3d007d447529400c14006287def
5 N6711eb9c629f4c77b1401af99e2d049d
6 N67c4ad99ac6f446b98f2328139a73b64
7 Nadfba30ed540455ba48c054ee1cb10f4
8 Nb24ab4bbfec8439ea0832e25bdd9fcb7
9 Nbec65b78c860445eb586c348fbb707bc
10 Ncacf0d3178884fdf8cca8eb9cb66b2a1
11 Nd698e7ebdf9041fc92ed114c2d063fd6
12 Ndc53a04d386f40f597dd2aa3a8334a3f
13 Nf5939870fea44b2bb56289e8700ce759
14 anzsrc-for:11
15 anzsrc-for:1103
16 schema:author N3c87036651754b5dbd6fa8a4a07db5df
17 schema:citation sg:pub.10.1007/bf00197554
18 sg:pub.10.1007/s004670050385
19 sg:pub.10.1023/a:1005533531756
20 sg:pub.10.1023/a:1026683531461
21 sg:pub.10.1038/ki.1992.366
22 https://app.dimensions.ai/details/publication/pub.1074587490
23 https://app.dimensions.ai/details/publication/pub.1076450987
24 https://app.dimensions.ai/details/publication/pub.1078589252
25 https://app.dimensions.ai/details/publication/pub.1083108687
26 https://app.dimensions.ai/details/publication/pub.1083116126
27 https://app.dimensions.ai/details/publication/pub.1083322928
28 https://app.dimensions.ai/details/publication/pub.1083369890
29 https://doi.org/10.1002/hep.1840210433
30 https://doi.org/10.1002/hep.510240512
31 https://doi.org/10.1002/hep.510260215
32 https://doi.org/10.1002/hep.510300130
33 https://doi.org/10.1006/abbi.1996.9847
34 https://doi.org/10.1006/jsre.1996.0310
35 https://doi.org/10.1016/0006-2952(94)90124-4
36 https://doi.org/10.1016/0925-4439(96)00031-2
37 https://doi.org/10.1016/s0009-8981(99)00138-2
38 https://doi.org/10.1016/s0024-3205(99)00668-2
39 https://doi.org/10.1016/s0041-1345(98)01222-6
40 https://doi.org/10.1016/s0891-5849(96)00571-0
41 https://doi.org/10.1016/s0925-4439(99)00114-3
42 https://doi.org/10.1042/bst0280136
43 https://doi.org/10.1073/pnas.76.9.4498
44 https://doi.org/10.1074/jbc.271.43.26863
45 https://doi.org/10.1111/j.1440-1681.1995.tb01992.x
46 https://doi.org/10.1139/o95-071
47 https://doi.org/10.1152/ajpgi.1994.267.4.g630
48 https://doi.org/10.1152/ajprenal.1999.276.4.f544
49 https://doi.org/10.1172/jci116223
50 schema:datePublished 2001-08
51 schema:datePublishedReg 2001-08-01
52 schema:description We studied and quantified the effect of ischemia-reperfusion on hepatic F-actin on bile canalicular and basolateral membranes in human liver allografts by means of confocal laser scanning microscopy imaging. The phalloidin-FITC staining of F-actin was normal in liver hepatocytes before reperfusion but decreased significantly after reperfusion (by 25% of controls). These results indicate that hepatic F-actin alteration is produced during the reperfusion phase. This modification, probably induced by reactive oxygen species, could impair bile canalicular contraction and tight junction permeability and consequently bile secretion in the postoperative period.
53 schema:genre research_article
54 schema:inLanguage en
55 schema:isAccessibleForFree false
56 schema:isPartOf N0b40304e61084867949bf83d5eb5d702
57 Nbcc17b63daae4e049c2091438ef4527f
58 sg:journal.1018525
59 schema:name Effect of Ischemia–Reperfusion on Bile Canalicular F-Actin Microfilaments in Hepatocytes of Human Liver Allograft
60 schema:pagination 1663-1667
61 schema:productId N4b5cfbb13e6446aea7cf604205b31bc5
62 N4d80a1e3814442dc8b71750f89c9952c
63 N5044499ab4c14fe1bdb75dcd792e0cb1
64 Nc7ee2beb66ad4f64a9add6a4e8180e1c
65 Ncebe0ce80c964df8b152bda32411e4d7
66 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039029411
67 https://doi.org/10.1023/a:1010693218680
68 schema:sdDatePublished 2019-04-10T19:54
69 schema:sdLicense https://scigraph.springernature.com/explorer/license/
70 schema:sdPublisher Na81c9c32d0904bef90ec6cd75add0e8a
71 schema:url http://link.springer.com/10.1023/A:1010693218680
72 sgo:license sg:explorer/license/
73 sgo:sdDataset articles
74 rdf:type schema:ScholarlyArticle
75 N0b40304e61084867949bf83d5eb5d702 schema:issueNumber 8
76 rdf:type schema:PublicationIssue
77 N0dc7396fd7e748dfa31b534833171951 rdf:first sg:person.01323057072.43
78 rdf:rest Ndb669d4b63fb406ca177310bc4edb4bc
79 N21b715735ad24f259bd5fcb36e6da383 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
80 schema:name Reperfusion Injury
81 rdf:type schema:DefinedTerm
82 N247311ed39de4c89808c13a17c0a17be rdf:first sg:person.01114620434.35
83 rdf:rest Nfd6db54ac7b54a718ab6c0a51482f6a8
84 N32a91f9737494b278a23ff4ac17e841c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
85 schema:name Coloring Agents
86 rdf:type schema:DefinedTerm
87 N396507c268c647cd9f9495dce29b63c7 schema:name Laboratoire de Pathologie Cellulaire et Métabolique du Foie, INSERM U 559, Faculté de Médecine, 27 boulevard Jean Moulin, 13385, Marseille Cedex 05, France
88 rdf:type schema:Organization
89 N3c87036651754b5dbd6fa8a4a07db5df rdf:first sg:person.072273167.74
90 rdf:rest N247311ed39de4c89808c13a17c0a17be
91 N3d35ddb832ad4046a546fa8438fa5fee schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
92 schema:name Actin Cytoskeleton
93 rdf:type schema:DefinedTerm
94 N4962d3d007d447529400c14006287def schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
95 schema:name Biopsy
96 rdf:type schema:DefinedTerm
97 N4b5cfbb13e6446aea7cf604205b31bc5 schema:name dimensions_id
98 schema:value pub.1039029411
99 rdf:type schema:PropertyValue
100 N4d80a1e3814442dc8b71750f89c9952c schema:name doi
101 schema:value 10.1023/a:1010693218680
102 rdf:type schema:PropertyValue
103 N5044499ab4c14fe1bdb75dcd792e0cb1 schema:name nlm_unique_id
104 schema:value 7902782
105 rdf:type schema:PropertyValue
106 N6711eb9c629f4c77b1401af99e2d049d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
107 schema:name Actins
108 rdf:type schema:DefinedTerm
109 N67c4ad99ac6f446b98f2328139a73b64 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
110 schema:name Hepatocytes
111 rdf:type schema:DefinedTerm
112 N6d1a1ce02e51488d8847ad09637982f9 rdf:first sg:person.01167131513.20
113 rdf:rest Ne090d29175e9487d9e37dbca66241b01
114 N944622b846334af1a6d254a349db4500 rdf:first sg:person.01012357464.43
115 rdf:rest rdf:nil
116 Na81c9c32d0904bef90ec6cd75add0e8a schema:name Springer Nature - SN SciGraph project
117 rdf:type schema:Organization
118 Nadfba30ed540455ba48c054ee1cb10f4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
119 schema:name Fluorescein-5-isothiocyanate
120 rdf:type schema:DefinedTerm
121 Nb24ab4bbfec8439ea0832e25bdd9fcb7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
122 schema:name Cell Membrane
123 rdf:type schema:DefinedTerm
124 Nb2dd37fb6ef04237a7e9529e1bfd58ad schema:name Laboratoire de Pathologie Cellulaire et Métabolique du Foie, INSERM U 559, Faculté de Médecine, 27 boulevard Jean Moulin, 13385, Marseille Cedex 05, France
125 rdf:type schema:Organization
126 Nb9612cc13130471bab92d2ea529ba155 schema:name Laboratoire de Pathologie Cellulaire et Métabolique du Foie, INSERM U 559, Faculté de Médecine, 27 boulevard Jean Moulin, 13385, Marseille Cedex 05, France
127 rdf:type schema:Organization
128 Nbcc17b63daae4e049c2091438ef4527f schema:volumeNumber 46
129 rdf:type schema:PublicationVolume
130 Nbec65b78c860445eb586c348fbb707bc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
131 schema:name Humans
132 rdf:type schema:DefinedTerm
133 Nc7ee2beb66ad4f64a9add6a4e8180e1c schema:name pubmed_id
134 schema:value 11508665
135 rdf:type schema:PropertyValue
136 Ncacf0d3178884fdf8cca8eb9cb66b2a1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
137 schema:name Liver Transplantation
138 rdf:type schema:DefinedTerm
139 Ncebe0ce80c964df8b152bda32411e4d7 schema:name readcube_id
140 schema:value b9ea63ae30f14ce768e7b76070b163d111359d45268f2a61a7deafabb93e2383
141 rdf:type schema:PropertyValue
142 Nd698e7ebdf9041fc92ed114c2d063fd6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
143 schema:name Phalloidine
144 rdf:type schema:DefinedTerm
145 Ndb669d4b63fb406ca177310bc4edb4bc rdf:first sg:person.01012356705.38
146 rdf:rest N6d1a1ce02e51488d8847ad09637982f9
147 Ndc53a04d386f40f597dd2aa3a8334a3f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
148 schema:name Microscopy, Confocal
149 rdf:type schema:DefinedTerm
150 Ne090d29175e9487d9e37dbca66241b01 rdf:first sg:person.01115256103.65
151 rdf:rest N944622b846334af1a6d254a349db4500
152 Nf5939870fea44b2bb56289e8700ce759 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
153 schema:name Bile Canaliculi
154 rdf:type schema:DefinedTerm
155 Nfd6db54ac7b54a718ab6c0a51482f6a8 rdf:first sg:person.0575737550.25
156 rdf:rest N0dc7396fd7e748dfa31b534833171951
157 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
158 schema:name Medical and Health Sciences
159 rdf:type schema:DefinedTerm
160 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
161 schema:name Clinical Sciences
162 rdf:type schema:DefinedTerm
163 sg:journal.1018525 schema:issn 0163-2116
164 1573-2568
165 schema:name Digestive Diseases and Sciences
166 rdf:type schema:Periodical
167 sg:person.01012356705.38 schema:affiliation https://www.grid.ac/institutes/grid.411535.7
168 schema:familyName Botta-Fridlund
169 schema:givenName Danielle
170 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01012356705.38
171 rdf:type schema:Person
172 sg:person.01012357464.43 schema:affiliation https://www.grid.ac/institutes/grid.411535.7
173 schema:familyName Chamlian
174 schema:givenName Albert
175 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01012357464.43
176 rdf:type schema:Person
177 sg:person.01114620434.35 schema:affiliation Nb9612cc13130471bab92d2ea529ba155
178 schema:familyName Dodero
179 schema:givenName Frank
180 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01114620434.35
181 rdf:type schema:Person
182 sg:person.01115256103.65 schema:affiliation https://www.grid.ac/institutes/grid.411535.7
183 schema:familyName Le Treut
184 schema:givenName Yves Patrice
185 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01115256103.65
186 rdf:type schema:Person
187 sg:person.01167131513.20 schema:affiliation N396507c268c647cd9f9495dce29b63c7
188 schema:familyName Lombardo
189 schema:givenName Dominique
190 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01167131513.20
191 rdf:type schema:Person
192 sg:person.01323057072.43 schema:affiliation https://www.grid.ac/institutes/grid.411535.7
193 schema:familyName Campan
194 schema:givenName Pierre
195 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01323057072.43
196 rdf:type schema:Person
197 sg:person.0575737550.25 schema:affiliation https://www.grid.ac/institutes/grid.411535.7
198 schema:familyName Hardwigsen
199 schema:givenName Jean
200 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0575737550.25
201 rdf:type schema:Person
202 sg:person.072273167.74 schema:affiliation Nb2dd37fb6ef04237a7e9529e1bfd58ad
203 schema:familyName Benkoël
204 schema:givenName Liliane
205 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.072273167.74
206 rdf:type schema:Person
207 sg:pub.10.1007/bf00197554 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039123967
208 https://doi.org/10.1007/bf00197554
209 rdf:type schema:CreativeWork
210 sg:pub.10.1007/s004670050385 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025663804
211 https://doi.org/10.1007/s004670050385
212 rdf:type schema:CreativeWork
213 sg:pub.10.1023/a:1005533531756 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053271734
214 https://doi.org/10.1023/a:1005533531756
215 rdf:type schema:CreativeWork
216 sg:pub.10.1023/a:1026683531461 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023659560
217 https://doi.org/10.1023/a:1026683531461
218 rdf:type schema:CreativeWork
219 sg:pub.10.1038/ki.1992.366 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031647035
220 https://doi.org/10.1038/ki.1992.366
221 rdf:type schema:CreativeWork
222 https://app.dimensions.ai/details/publication/pub.1074587490 schema:CreativeWork
223 https://app.dimensions.ai/details/publication/pub.1076450987 schema:CreativeWork
224 https://app.dimensions.ai/details/publication/pub.1078589252 schema:CreativeWork
225 https://app.dimensions.ai/details/publication/pub.1083108687 schema:CreativeWork
226 https://app.dimensions.ai/details/publication/pub.1083116126 schema:CreativeWork
227 https://app.dimensions.ai/details/publication/pub.1083322928 schema:CreativeWork
228 https://app.dimensions.ai/details/publication/pub.1083369890 schema:CreativeWork
229 https://doi.org/10.1002/hep.1840210433 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041479281
230 rdf:type schema:CreativeWork
231 https://doi.org/10.1002/hep.510240512 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037669242
232 rdf:type schema:CreativeWork
233 https://doi.org/10.1002/hep.510260215 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026461614
234 rdf:type schema:CreativeWork
235 https://doi.org/10.1002/hep.510300130 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049068907
236 rdf:type schema:CreativeWork
237 https://doi.org/10.1006/abbi.1996.9847 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024017127
238 rdf:type schema:CreativeWork
239 https://doi.org/10.1006/jsre.1996.0310 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040630053
240 rdf:type schema:CreativeWork
241 https://doi.org/10.1016/0006-2952(94)90124-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028685064
242 rdf:type schema:CreativeWork
243 https://doi.org/10.1016/0925-4439(96)00031-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024629909
244 rdf:type schema:CreativeWork
245 https://doi.org/10.1016/s0009-8981(99)00138-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000985075
246 rdf:type schema:CreativeWork
247 https://doi.org/10.1016/s0024-3205(99)00668-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028852422
248 rdf:type schema:CreativeWork
249 https://doi.org/10.1016/s0041-1345(98)01222-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016714659
250 rdf:type schema:CreativeWork
251 https://doi.org/10.1016/s0891-5849(96)00571-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027651916
252 rdf:type schema:CreativeWork
253 https://doi.org/10.1016/s0925-4439(99)00114-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046169805
254 rdf:type schema:CreativeWork
255 https://doi.org/10.1042/bst0280136 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001675782
256 rdf:type schema:CreativeWork
257 https://doi.org/10.1073/pnas.76.9.4498 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050098152
258 rdf:type schema:CreativeWork
259 https://doi.org/10.1074/jbc.271.43.26863 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024230779
260 rdf:type schema:CreativeWork
261 https://doi.org/10.1111/j.1440-1681.1995.tb01992.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1002741562
262 rdf:type schema:CreativeWork
263 https://doi.org/10.1139/o95-071 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013232408
264 rdf:type schema:CreativeWork
265 https://doi.org/10.1152/ajpgi.1994.267.4.g630 schema:sameAs https://app.dimensions.ai/details/publication/pub.1082576623
266 rdf:type schema:CreativeWork
267 https://doi.org/10.1152/ajprenal.1999.276.4.f544 schema:sameAs https://app.dimensions.ai/details/publication/pub.1074356309
268 rdf:type schema:CreativeWork
269 https://doi.org/10.1172/jci116223 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028592002
270 rdf:type schema:CreativeWork
271 https://www.grid.ac/institutes/grid.411535.7 schema:alternateName Hôpital de la Conception
272 schema:name Service d'Hépato-Gastroentérologie, Hôpital de la Conception, 147 bd. Baille, 13385, Marseille Cedex 05, France
273 Unité de Transplantation Hépatique, Hôpital de la Conception, 147 bd. Baille, 13385, Marseille Cedex 05, France
274 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...