On-line recovery of large molecules and concentration of small molecules using reciprocating size exclusion chromatography with temperature swing View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1999-11

AUTHORS

Woo-Jin Chang, Yoon-Mo Koo

ABSTRACT

The reciprocating size exclusion chromatography (RSEC) was operated with swing between two temperatures in a synchronous way with flow direction to recover a large solute on-line from the mixture, in addition to the small solute concentration. The concentration of small solutes in RSEC with a temperature swing was made possible by taking advantage of the temperature-dependent swelling properties of the porous gel. After 7 cycles of frontal mode operation, 76% of Blue Dextran in the feed was recovered and nickel nitrate in the feed reservoir was concentrated by 13%. More... »

PAGES

809-812

Journal

TITLE

Biotechnology Letters

ISSUE

11

VOLUME

13

Author Affiliations

Identifiers

URI

http://scigraph.springernature.com/pub.10.1023/a:1008908819151

DOI

http://dx.doi.org/10.1023/a:1008908819151

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1038359725


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