Cancer risk following appendectomy for acute appendicitis (Denmark) View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1998-03

AUTHORS

Lene Mellemkjær, Christoffer Johansen, Martha S. Linet, Gloria Gridley, Jørgen H. Olsen

ABSTRACT

OBJECTIVE: Epidemiologic studies have not been able definitely to exclude that appendectomy carries a cancer risk. This study was conducted to clarify whether appendectomy is associated with a subsequent increase in cancer risk, since appendectomy is frequently an elective procedure. METHODS: The present study included more than 82,000 persons who underwent appendectomy for acute appendicitis during 1977-89 according to the nation-wide Danish Hospital Discharge Register. During a follow-up interval of up to 17 years, cancer incidence was assessed by linkage to the Danish Cancer Registry and compared with the incidence in the general population of Denmark. RESULTS: The total number of malignancies among appendectomized persons was 1.05 times higher than expected with 95 percent confidence intervals of 0.99-1.11. There was no clear significant excess of any specific cancer type. CONCLUSION: During a postsurgery period of nearly two decades, results of our study did not support the hypothesis that either appendectomy or acute appendicitis are likely to be associated with malignant neoplasms. More... »

PAGES

183-187

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1023/a:1008834311514

DOI

http://dx.doi.org/10.1023/a:1008834311514

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1024627823

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/9578295


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