Sequence Analysis of the Gene Encoding VP4 of a Bovine Group C Rotavirus: Molecular Evidence for a New P Genotype View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1999-07

AUTHORS

B. Jiang, J.R. Gentsch, H. Tsunemitsu, L.J. Saif, R.I. Glass

ABSTRACT

Nucleotide sequence of the bovine group C rotavirus Shintoku strain gene 3 was determined. Segment 3 is 2253 nucleotides (nt) in length and contains a long open reading frame (ORF) beginning at nt 22 and terminating at nt 2223. This ORF encodes a polypeptide of 733 amino acids with a predicted molecular mass of 83 kDa. The deduced gene 3 amino acid sequence shares 79% and 73% identities with VP4 of the porcine Cowden and human Bristol strains, respectively. Lack of high amino acid sequence homology in VP4 of bovine, porcine, and human group C rotaviruses indicates that the Shintoku strain represents a new P genotype. More... »

PAGES

85-88

Identifiers

URI

http://scigraph.springernature.com/pub.10.1023/a:1008196824879

DOI

http://dx.doi.org/10.1023/a:1008196824879

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1010279198

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/10499454


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