Comparisons of Nucleotide and Deduced Amino Acid Sequences of NSP4 Genes of Virulent and Attenuated Pairs of Group A and ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1999-06

AUTHORS

K.O. Chang, Y.J. Kim, L.J. Saif

ABSTRACT

The NSP4 protein of rotavirus is a nonstructural glycoprotein and has a crucial function in virus morphogenesis during infection of host cells. It was recently reported that NSP4 may also function as a viral enterotoxin in the induction of rotavirus diarrhea by causing Ca++ influx in the cytoplasm of the infected cells. We sequenced and analyzed two (Wa and M strains) pairs of NSP4 genes of virulent (v) and attenuated (a) (after 30 to 40 passages in cell culture) human group A rotaviruses and a pair of NSP4 genes of virulent and attenuated porcine group C rotavirus (Cowden strain). These strains were previously identified as virulent (induce diarrhea) or attenuated (no diarrhea) in a gnotobiotic pig model of rotavirus infection [Bohl et al. (4), Saif et al. (13), Ward et al. (17)]. The NSP4 genes of the Wa, M and Cowden strains were amplified with RT-PCR using a proof reading polymerase (Tli) and the RT-PCR product was sequenced directly. Analysis of the NSP4 deduced amino acid sequences showed that only 3 (Wa) and 2 (M and Cowden) amino acids differed between the virulent and attenuated strains. For the Wa strain, the changes from the virulent to attenuated strain were in amino acids 13 (V to A), 16 (L to S) and 34 (P to L); in the M strain, the difference was in amino acids 53 (T to I) and 104 (K to E), and in the Cowden strains, amino acids 50 (L to F) and 97 (D to N) differed between virulent and attenuated strains. To our knowledge, this is the first sequence comparison between NSP4 of a virulent and attenuated pair of group C rotaviruses. The potential impact of these few amino acid changes on the pathogenesis of the NSP4 protein for piglets is unclear, relative to previous findings in mice (1), but requires further study using purified recombinant NSP4 proteins or peptides. More... »

PAGES

229-233

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1023/a:1008068218966

DOI

http://dx.doi.org/10.1023/a:1008068218966

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1042930628

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/10456791


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1108", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical Microbiology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Amino Acid Sequence", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Base Sequence", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "DNA, Viral", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "DNA-Directed RNA Polymerases", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mice", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Molecular Sequence Data", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Reverse Transcriptase Polymerase Chain Reaction", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rotavirus", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sequence Homology, Amino Acid", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Species Specificity", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Swine", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Viral Nonstructural Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Virulence", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "The Ohio State University", 
          "id": "https://www.grid.ac/institutes/grid.261331.4", 
          "name": [
            "Food Animal Health Research Program, Ohio Agricultural Research and Development Center, Department of Veterinary Preventive Medicine, The Ohio State University, 44691, Wooster, OH"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chang", 
        "givenName": "K.O.", 
        "id": "sg:person.01266374732.53", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01266374732.53"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The Ohio State University", 
          "id": "https://www.grid.ac/institutes/grid.261331.4", 
          "name": [
            "Food Animal Health Research Program, Ohio Agricultural Research and Development Center, Department of Veterinary Preventive Medicine, The Ohio State University, 44691, Wooster, OH"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kim", 
        "givenName": "Y.J.", 
        "id": "sg:person.01273145570.39", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01273145570.39"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The Ohio State University", 
          "id": "https://www.grid.ac/institutes/grid.261331.4", 
          "name": [
            "Food Animal Health Research Program, Ohio Agricultural Research and Development Center, Department of Veterinary Preventive Medicine, The Ohio State University, 44691, Wooster, OH"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Saif", 
        "givenName": "L.J.", 
        "id": "sg:person.011005227177.12", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011005227177.12"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/bf01701813", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010248339", 
          "https://doi.org/10.1007/bf01701813"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01701813", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010248339", 
          "https://doi.org/10.1007/bf01701813"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01701813", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010248339", 
          "https://doi.org/10.1007/bf01701813"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/(sici)1096-9071(199709)53:1<41::aid-jmv8>3.0.co;2-q", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010769706"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00005176-198803000-00017", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030477091"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00005176-198803000-00017", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030477091"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/viro.1995.1255", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047766595"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1086/517374", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1058790972"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1099/0022-1317-77-7-1431", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060360048"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.272.5258.101", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062552617"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.6243190", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062635818"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078151583", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079018267", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079025226", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079420372", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081658647", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082444486", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082957643", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083039602", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083117418", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083249065", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1999-06", 
    "datePublishedReg": "1999-06-01", 
    "description": "The NSP4 protein of rotavirus is a nonstructural glycoprotein and has a crucial function in virus morphogenesis during infection of host cells. It was recently reported that NSP4 may also function as a viral enterotoxin in the induction of rotavirus diarrhea by causing Ca++ influx in the cytoplasm of the infected cells. We sequenced and analyzed two (Wa and M strains) pairs of NSP4 genes of virulent (v) and attenuated (a) (after 30 to 40 passages in cell culture) human group A rotaviruses and a pair of NSP4 genes of virulent and attenuated porcine group C rotavirus (Cowden strain). These strains were previously identified as virulent (induce diarrhea) or attenuated (no diarrhea) in a gnotobiotic pig model of rotavirus infection [Bohl et al. (4), Saif et al. (13), Ward et al. (17)]. The NSP4 genes of the Wa, M and Cowden strains were amplified with RT-PCR using a proof reading polymerase (Tli) and the RT-PCR product was sequenced directly. Analysis of the NSP4 deduced amino acid sequences showed that only 3 (Wa) and 2 (M and Cowden) amino acids differed between the virulent and attenuated strains. For the Wa strain, the changes from the virulent to attenuated strain were in amino acids 13 (V to A), 16 (L to S) and 34 (P to L); in the M strain, the difference was in amino acids 53 (T to I) and 104 (K to E), and in the Cowden strains, amino acids 50 (L to F) and 97 (D to N) differed between virulent and attenuated strains. To our knowledge, this is the first sequence comparison between NSP4 of a virulent and attenuated pair of group C rotaviruses. The potential impact of these few amino acid changes on the pathogenesis of the NSP4 protein for piglets is unclear, relative to previous findings in mice (1), but requires further study using purified recombinant NSP4 proteins or peptides.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1023/a:1008068218966", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1097920", 
        "issn": [
          "0920-8569", 
          "1572-994X"
        ], 
        "name": "Virus Genes", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "3", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "18"
      }
    ], 
    "name": "Comparisons of Nucleotide and Deduced Amino Acid Sequences of NSP4 Genes of Virulent and Attenuated Pairs of Group A and C Rotaviruses", 
    "pagination": "229-233", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "cc7e62e1ff96293b0e139c989267ec14a13b2253b2a4783fa21c7cf214857533"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "10456791"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "8803967"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1023/a:1008068218966"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1042930628"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1023/a:1008068218966", 
      "https://app.dimensions.ai/details/publication/pub.1042930628"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T15:56", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8664_00000537.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1023%2FA%3A1008068218966"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1023/a:1008068218966'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1023/a:1008068218966'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1023/a:1008068218966'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1023/a:1008068218966'


 

This table displays all metadata directly associated to this object as RDF triples.

188 TRIPLES      21 PREDICATES      62 URIs      36 LITERALS      24 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1023/a:1008068218966 schema:about N01cd863bb9b84e34b80cda2402ecc0be
2 N0e3193e81eb84f04af3f2d64b0ae43fe
3 N1cb9d88276b94a4baff15103555ce099
4 N2432aa61d68848e19c201f6164a1ecf2
5 N2a31f68db88a46cdbb7529c8720c3513
6 N2f1a6c6e992448dca4e082059f88269b
7 N3a84c1de7f24431081316dbd86e3e196
8 N3f9d83b0dc8e4c61906bf4450bfab63b
9 N50542891e0174695b35586abee963512
10 N9aa01a11c1954ef6aeeb39d34dc965fd
11 Na1273f9a61264af9853e5e0829122c92
12 Nae4a93c330674b71acb97529667d6c26
13 Nd89f8a5c28c24916988d87556c5a1b2c
14 Ndff526aa134a485b8b6257eb9a8658b0
15 Ne0de7d3a23214ff3bca717edd51eee93
16 anzsrc-for:11
17 anzsrc-for:1108
18 schema:author N08ed31778fe94508a7abf9d8ee4f81bc
19 schema:citation sg:pub.10.1007/bf01701813
20 https://app.dimensions.ai/details/publication/pub.1078151583
21 https://app.dimensions.ai/details/publication/pub.1079018267
22 https://app.dimensions.ai/details/publication/pub.1079025226
23 https://app.dimensions.ai/details/publication/pub.1079420372
24 https://app.dimensions.ai/details/publication/pub.1081658647
25 https://app.dimensions.ai/details/publication/pub.1082444486
26 https://app.dimensions.ai/details/publication/pub.1082957643
27 https://app.dimensions.ai/details/publication/pub.1083039602
28 https://app.dimensions.ai/details/publication/pub.1083117418
29 https://app.dimensions.ai/details/publication/pub.1083249065
30 https://doi.org/10.1002/(sici)1096-9071(199709)53:1<41::aid-jmv8>3.0.co;2-q
31 https://doi.org/10.1006/viro.1995.1255
32 https://doi.org/10.1086/517374
33 https://doi.org/10.1097/00005176-198803000-00017
34 https://doi.org/10.1099/0022-1317-77-7-1431
35 https://doi.org/10.1126/science.272.5258.101
36 https://doi.org/10.1126/science.6243190
37 schema:datePublished 1999-06
38 schema:datePublishedReg 1999-06-01
39 schema:description The NSP4 protein of rotavirus is a nonstructural glycoprotein and has a crucial function in virus morphogenesis during infection of host cells. It was recently reported that NSP4 may also function as a viral enterotoxin in the induction of rotavirus diarrhea by causing Ca++ influx in the cytoplasm of the infected cells. We sequenced and analyzed two (Wa and M strains) pairs of NSP4 genes of virulent (v) and attenuated (a) (after 30 to 40 passages in cell culture) human group A rotaviruses and a pair of NSP4 genes of virulent and attenuated porcine group C rotavirus (Cowden strain). These strains were previously identified as virulent (induce diarrhea) or attenuated (no diarrhea) in a gnotobiotic pig model of rotavirus infection [Bohl et al. (4), Saif et al. (13), Ward et al. (17)]. The NSP4 genes of the Wa, M and Cowden strains were amplified with RT-PCR using a proof reading polymerase (Tli) and the RT-PCR product was sequenced directly. Analysis of the NSP4 deduced amino acid sequences showed that only 3 (Wa) and 2 (M and Cowden) amino acids differed between the virulent and attenuated strains. For the Wa strain, the changes from the virulent to attenuated strain were in amino acids 13 (V to A), 16 (L to S) and 34 (P to L); in the M strain, the difference was in amino acids 53 (T to I) and 104 (K to E), and in the Cowden strains, amino acids 50 (L to F) and 97 (D to N) differed between virulent and attenuated strains. To our knowledge, this is the first sequence comparison between NSP4 of a virulent and attenuated pair of group C rotaviruses. The potential impact of these few amino acid changes on the pathogenesis of the NSP4 protein for piglets is unclear, relative to previous findings in mice (1), but requires further study using purified recombinant NSP4 proteins or peptides.
40 schema:genre research_article
41 schema:inLanguage en
42 schema:isAccessibleForFree false
43 schema:isPartOf N9e6f108482334ac589825f52570a71a3
44 Nc081b6702d9e4a6da05094a1038269a1
45 sg:journal.1097920
46 schema:name Comparisons of Nucleotide and Deduced Amino Acid Sequences of NSP4 Genes of Virulent and Attenuated Pairs of Group A and C Rotaviruses
47 schema:pagination 229-233
48 schema:productId N063293811bd241d2a7fba559617b5d0d
49 N15cb5e4a8443426e81ca76e138d079ce
50 N3595da1f5ed24e22841dfd802618ebba
51 N400bd5b25f6e4ca4871c2360951f5855
52 Nd65c1083061c4727b13b4c00a6a4179f
53 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042930628
54 https://doi.org/10.1023/a:1008068218966
55 schema:sdDatePublished 2019-04-10T15:56
56 schema:sdLicense https://scigraph.springernature.com/explorer/license/
57 schema:sdPublisher N414e645db3b14eb5a65bb7a7557bebbf
58 schema:url http://link.springer.com/10.1023%2FA%3A1008068218966
59 sgo:license sg:explorer/license/
60 sgo:sdDataset articles
61 rdf:type schema:ScholarlyArticle
62 N01cd863bb9b84e34b80cda2402ecc0be schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
63 schema:name Swine
64 rdf:type schema:DefinedTerm
65 N063293811bd241d2a7fba559617b5d0d schema:name dimensions_id
66 schema:value pub.1042930628
67 rdf:type schema:PropertyValue
68 N08ed31778fe94508a7abf9d8ee4f81bc rdf:first sg:person.01266374732.53
69 rdf:rest N5433a5eeb6f94e45b7638cee55f096fa
70 N0e3193e81eb84f04af3f2d64b0ae43fe schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
71 schema:name Amino Acid Sequence
72 rdf:type schema:DefinedTerm
73 N15cb5e4a8443426e81ca76e138d079ce schema:name doi
74 schema:value 10.1023/a:1008068218966
75 rdf:type schema:PropertyValue
76 N1cb9d88276b94a4baff15103555ce099 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
77 schema:name Reverse Transcriptase Polymerase Chain Reaction
78 rdf:type schema:DefinedTerm
79 N2432aa61d68848e19c201f6164a1ecf2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
80 schema:name Sequence Homology, Amino Acid
81 rdf:type schema:DefinedTerm
82 N2a31f68db88a46cdbb7529c8720c3513 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
83 schema:name DNA, Viral
84 rdf:type schema:DefinedTerm
85 N2f1a6c6e992448dca4e082059f88269b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
86 schema:name Mice
87 rdf:type schema:DefinedTerm
88 N3595da1f5ed24e22841dfd802618ebba schema:name nlm_unique_id
89 schema:value 8803967
90 rdf:type schema:PropertyValue
91 N3a84c1de7f24431081316dbd86e3e196 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
92 schema:name Humans
93 rdf:type schema:DefinedTerm
94 N3f9d83b0dc8e4c61906bf4450bfab63b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
95 schema:name Virulence
96 rdf:type schema:DefinedTerm
97 N400bd5b25f6e4ca4871c2360951f5855 schema:name pubmed_id
98 schema:value 10456791
99 rdf:type schema:PropertyValue
100 N414e645db3b14eb5a65bb7a7557bebbf schema:name Springer Nature - SN SciGraph project
101 rdf:type schema:Organization
102 N50542891e0174695b35586abee963512 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
103 schema:name Base Sequence
104 rdf:type schema:DefinedTerm
105 N5433a5eeb6f94e45b7638cee55f096fa rdf:first sg:person.01273145570.39
106 rdf:rest N842774f5f4dc44b7b4077bebf5cd0099
107 N842774f5f4dc44b7b4077bebf5cd0099 rdf:first sg:person.011005227177.12
108 rdf:rest rdf:nil
109 N9aa01a11c1954ef6aeeb39d34dc965fd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
110 schema:name Animals
111 rdf:type schema:DefinedTerm
112 N9e6f108482334ac589825f52570a71a3 schema:issueNumber 3
113 rdf:type schema:PublicationIssue
114 Na1273f9a61264af9853e5e0829122c92 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
115 schema:name Species Specificity
116 rdf:type schema:DefinedTerm
117 Nae4a93c330674b71acb97529667d6c26 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
118 schema:name Molecular Sequence Data
119 rdf:type schema:DefinedTerm
120 Nc081b6702d9e4a6da05094a1038269a1 schema:volumeNumber 18
121 rdf:type schema:PublicationVolume
122 Nd65c1083061c4727b13b4c00a6a4179f schema:name readcube_id
123 schema:value cc7e62e1ff96293b0e139c989267ec14a13b2253b2a4783fa21c7cf214857533
124 rdf:type schema:PropertyValue
125 Nd89f8a5c28c24916988d87556c5a1b2c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
126 schema:name DNA-Directed RNA Polymerases
127 rdf:type schema:DefinedTerm
128 Ndff526aa134a485b8b6257eb9a8658b0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
129 schema:name Rotavirus
130 rdf:type schema:DefinedTerm
131 Ne0de7d3a23214ff3bca717edd51eee93 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
132 schema:name Viral Nonstructural Proteins
133 rdf:type schema:DefinedTerm
134 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
135 schema:name Medical and Health Sciences
136 rdf:type schema:DefinedTerm
137 anzsrc-for:1108 schema:inDefinedTermSet anzsrc-for:
138 schema:name Medical Microbiology
139 rdf:type schema:DefinedTerm
140 sg:journal.1097920 schema:issn 0920-8569
141 1572-994X
142 schema:name Virus Genes
143 rdf:type schema:Periodical
144 sg:person.011005227177.12 schema:affiliation https://www.grid.ac/institutes/grid.261331.4
145 schema:familyName Saif
146 schema:givenName L.J.
147 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011005227177.12
148 rdf:type schema:Person
149 sg:person.01266374732.53 schema:affiliation https://www.grid.ac/institutes/grid.261331.4
150 schema:familyName Chang
151 schema:givenName K.O.
152 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01266374732.53
153 rdf:type schema:Person
154 sg:person.01273145570.39 schema:affiliation https://www.grid.ac/institutes/grid.261331.4
155 schema:familyName Kim
156 schema:givenName Y.J.
157 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01273145570.39
158 rdf:type schema:Person
159 sg:pub.10.1007/bf01701813 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010248339
160 https://doi.org/10.1007/bf01701813
161 rdf:type schema:CreativeWork
162 https://app.dimensions.ai/details/publication/pub.1078151583 schema:CreativeWork
163 https://app.dimensions.ai/details/publication/pub.1079018267 schema:CreativeWork
164 https://app.dimensions.ai/details/publication/pub.1079025226 schema:CreativeWork
165 https://app.dimensions.ai/details/publication/pub.1079420372 schema:CreativeWork
166 https://app.dimensions.ai/details/publication/pub.1081658647 schema:CreativeWork
167 https://app.dimensions.ai/details/publication/pub.1082444486 schema:CreativeWork
168 https://app.dimensions.ai/details/publication/pub.1082957643 schema:CreativeWork
169 https://app.dimensions.ai/details/publication/pub.1083039602 schema:CreativeWork
170 https://app.dimensions.ai/details/publication/pub.1083117418 schema:CreativeWork
171 https://app.dimensions.ai/details/publication/pub.1083249065 schema:CreativeWork
172 https://doi.org/10.1002/(sici)1096-9071(199709)53:1<41::aid-jmv8>3.0.co;2-q schema:sameAs https://app.dimensions.ai/details/publication/pub.1010769706
173 rdf:type schema:CreativeWork
174 https://doi.org/10.1006/viro.1995.1255 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047766595
175 rdf:type schema:CreativeWork
176 https://doi.org/10.1086/517374 schema:sameAs https://app.dimensions.ai/details/publication/pub.1058790972
177 rdf:type schema:CreativeWork
178 https://doi.org/10.1097/00005176-198803000-00017 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030477091
179 rdf:type schema:CreativeWork
180 https://doi.org/10.1099/0022-1317-77-7-1431 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060360048
181 rdf:type schema:CreativeWork
182 https://doi.org/10.1126/science.272.5258.101 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062552617
183 rdf:type schema:CreativeWork
184 https://doi.org/10.1126/science.6243190 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062635818
185 rdf:type schema:CreativeWork
186 https://www.grid.ac/institutes/grid.261331.4 schema:alternateName The Ohio State University
187 schema:name Food Animal Health Research Program, Ohio Agricultural Research and Development Center, Department of Veterinary Preventive Medicine, The Ohio State University, 44691, Wooster, OH
188 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...