Development of 99mTc-labelled complexes for imaging dopamine transporters in the brain View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1998-08

AUTHORS

Hank F. Kung, Sanath Meegalla, Mei-Ping Kung, Karl Plössl

ABSTRACT

Technetium-99m (T1/2=6h, 140keV) is the most commonly used short-lived radionuclide for diagnostic nuclear medicine imaging. It is important from an inorganic chemistry point of view to develop novel ligands and chelation chemistry associated with this radionuclide, because many patients could potentially benefit from advances in technetium chemistry. Recent studies showed that formation of tropane derivatives containing a neutral [TcVO]3+N2S2 complex are useful as dopamine transporter imaging agents. These agents may be important for the imaging of patients with Parkinson's and other neurodegenerative diseases. More... »

PAGES

531-536

Journal

TITLE

Transition Metal Chemistry

ISSUE

4

VOLUME

23

Author Affiliations

Identifiers

URI

http://scigraph.springernature.com/pub.10.1023/a:1006921811871

DOI

http://dx.doi.org/10.1023/a:1006921811871

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1006108530


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