The IRS-signalling system: A network of docking proteins that mediate insulin action View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1998-05

AUTHORS

Morris F. White

ABSTRACT

New molecules discovered during the past ten years have created a rational framework to understand signalling transduction by a broad range of growth factors and cytokines, including insulin. Insulin action is initiated through the insulin receptor, a transmembrane glycoprotein with intrinsic protein tyrosine kinase activity. The tyrosine kinase mediates the insulin response through tyrosine phosphorylation of various cellular substrates, in particular the IRS-proteins. During insulin-stimulated tyrosine phosphorylation, the IRS-proteins mediate a broad biological response by binding and activating various enzymes or adapter molecules. Although we are far from a complete understanding of the insulin signalling system and its failure, enough pieces of the puzzle are falling into place that mechanism-based solutions to insulin resistance encountered with type II diabetes may soon be attainable. More... »

PAGES

3-11

Identifiers

URI

http://scigraph.springernature.com/pub.10.1023/a:1006806722619

DOI

http://dx.doi.org/10.1023/a:1006806722619

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1003203012

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/9609109


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biochemistry and Cell Biology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adaptor Proteins, Signal Transducing", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "DNA-Binding Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Insulin", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Insulin Receptor Substrate Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Intracellular Signaling Peptides and Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Phosphoproteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "RNA-Binding Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Receptor, Insulin", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Signal Transduction", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Harvard University", 
          "id": "https://www.grid.ac/institutes/grid.38142.3c", 
          "name": [
            "Research Division, Joslin Diabetes Center and the Graduate Program in Biomedical and Biological Sciences, Harvard Medical School, 02215, Boston, MA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "White", 
        "givenName": "Morris F.", 
        "id": "sg:person.013274422527.22", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013274422527.22"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1073/pnas.90.9.4032", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000550130"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1172/jci117936", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002666005"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.271.35.21353", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002684494"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(95)92779-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003277582"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(95)92779-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003277582"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/379277a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004867089", 
          "https://doi.org/10.1038/379277a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/mcb.16.6.2857", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006424023"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.272.4.2551", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006696264"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/373573a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008518821", 
          "https://doi.org/10.1038/373573a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1172/jci118705", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011763092"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/mcb.17.3.1513", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011983895"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/363088a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012003451", 
          "https://doi.org/10.1038/363088a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0092-8674(00)81872-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012374589"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.272.17.11663", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012647919"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0092-8674(92)90098-w", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013048571"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.271.20.11641", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013529886"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.271.11.5980", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014169912"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.271.16.9287", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014625481"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/geno.1996.0527", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017641030"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0968-0004(93)90031-h", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021057942"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0092-8674(00)81840-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021110000"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/377173a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022346115", 
          "https://doi.org/10.1038/377173a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/318183a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025875577", 
          "https://doi.org/10.1038/318183a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.89.23.11239", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028916365"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0092-8674(00)81841-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029007273"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/380075a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029942479", 
          "https://doi.org/10.1038/380075a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.271.17.10200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030074808"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/367474a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030955834", 
          "https://doi.org/10.1038/367474a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/mcb.15.8.4232", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031140582"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0092-8674(00)81896-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033103168"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.270.8.3662", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033744443"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/bbrc.1996.6047", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033814329"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/mcb.14.10.6674", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034251442"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/mcb.16.6.3074", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037306349"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.270.49.29189", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037488975"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/mcb.16.5.2195", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041494890"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/378785a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042289302", 
          "https://doi.org/10.1038/378785a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.271.18.10583", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042649232"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/379560a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043414343", 
          "https://doi.org/10.1038/379560a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0092-8674(00)81236-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044381040"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0960-9822(00)00087-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044470864"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/352073a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045276619", 
          "https://doi.org/10.1038/352073a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.90.24.11713", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045670198"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.271.10.5317", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046152080"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/372182a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046415369", 
          "https://doi.org/10.1038/372182a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0092-8674(95)90534-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046701590"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.272.17.11439", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047223115"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0092-8674(93)90232-f", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047403207"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0167-4889(94)90261-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048178823"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0167-4889(94)90261-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048178823"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/372186a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049271444", 
          "https://doi.org/10.1038/372186a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/mcb.14.6.3577", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049809042"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.92.3.664", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049854353"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1098/rstb.1996.0011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051309270"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/mcb.15.8.4453", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052321072"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0092-8674(00)81274-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052346632"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/mcb.16.8.4147", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053538402"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi9630974", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055213374"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi9630974", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055213374"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.271.5249.665", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062552146"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.275.5300.628", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062555644"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.275.5300.661", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062555654"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.7527156", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062647434"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.7701324", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062648976"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.8096088", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062652249"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.8316835", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062654639"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/mend.11.2.9885", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064331421"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2337/diabetes.43.11.1271", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1070742700"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1075455459", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082393661", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082397758", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082467503", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082597216", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082619572", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082653590", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082653592", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/j.1460-2075.1994.tb06289.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1082752641"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082783969", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/j.1460-2075.1993.tb05842.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1082829517"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082835552", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082839940", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082888489", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/j.1460-2075.1996.tb01045.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083023835"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1998-05", 
    "datePublishedReg": "1998-05-01", 
    "description": "New molecules discovered during the past ten years have created a rational framework to understand signalling transduction by a broad range of growth factors and cytokines, including insulin. Insulin action is initiated through the insulin receptor, a transmembrane glycoprotein with intrinsic protein tyrosine kinase activity. The tyrosine kinase mediates the insulin response through tyrosine phosphorylation of various cellular substrates, in particular the IRS-proteins. During insulin-stimulated tyrosine phosphorylation, the IRS-proteins mediate a broad biological response by binding and activating various enzymes or adapter molecules. Although we are far from a complete understanding of the insulin signalling system and its failure, enough pieces of the puzzle are falling into place that mechanism-based solutions to insulin resistance encountered with type II diabetes may soon be attainable.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1023/a:1006806722619", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.2664872", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2627419", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2494482", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2493645", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1016672", 
        "issn": [
          "0300-8177", 
          "1573-4919"
        ], 
        "name": "Molecular and Cellular Biochemistry", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1-2", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "182"
      }
    ], 
    "name": "The IRS-signalling system: A network of docking proteins that mediate insulin action", 
    "pagination": "3-11", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "0f41cdbb39cb51e2a873543388a6f6951195bb766afd73d408b5361156c2fe8b"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "9609109"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "0364456"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1023/a:1006806722619"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1003203012"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1023/a:1006806722619", 
      "https://app.dimensions.ai/details/publication/pub.1003203012"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T23:21", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8693_00000498.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1023/A:1006806722619"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1023/a:1006806722619'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1023/a:1006806722619'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1023/a:1006806722619'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1023/a:1006806722619'


 

This table displays all metadata directly associated to this object as RDF triples.

361 TRIPLES      21 PREDICATES      120 URIs      32 LITERALS      20 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1023/a:1006806722619 schema:about N0f48c1259cc34603bf282a151325b35b
2 N173a3c6666de458e8094c2dfb7654c7c
3 N17f836587cbc4497b2a603c2fc2cb299
4 N3ed740b4bc9b41569ac75adaf9066487
5 N624bc9c7b67c44bbba15cedf2cc54b45
6 N68b97df604964ec59c76e5ff7b51cfba
7 N7c113395e37b4a1dbeef217708ecb563
8 N8f19b4717d31470aa09fadabb01999bd
9 Nd1e1e23aebd54e9aa2b5594cf01cc735
10 Nd3056083d0ac45a9942b53fed64aa637
11 Ne401a20402634e848b8f854d174ae471
12 anzsrc-for:06
13 anzsrc-for:0601
14 schema:author N744d746125db4e5387061fcbaaf2db4d
15 schema:citation sg:pub.10.1038/318183a0
16 sg:pub.10.1038/352073a0
17 sg:pub.10.1038/363088a0
18 sg:pub.10.1038/367474a0
19 sg:pub.10.1038/372182a0
20 sg:pub.10.1038/372186a0
21 sg:pub.10.1038/373573a0
22 sg:pub.10.1038/377173a0
23 sg:pub.10.1038/378785a0
24 sg:pub.10.1038/379277a0
25 sg:pub.10.1038/379560a0
26 sg:pub.10.1038/380075a0
27 https://app.dimensions.ai/details/publication/pub.1075455459
28 https://app.dimensions.ai/details/publication/pub.1082393661
29 https://app.dimensions.ai/details/publication/pub.1082397758
30 https://app.dimensions.ai/details/publication/pub.1082467503
31 https://app.dimensions.ai/details/publication/pub.1082597216
32 https://app.dimensions.ai/details/publication/pub.1082619572
33 https://app.dimensions.ai/details/publication/pub.1082653590
34 https://app.dimensions.ai/details/publication/pub.1082653592
35 https://app.dimensions.ai/details/publication/pub.1082783969
36 https://app.dimensions.ai/details/publication/pub.1082835552
37 https://app.dimensions.ai/details/publication/pub.1082839940
38 https://app.dimensions.ai/details/publication/pub.1082888489
39 https://doi.org/10.1002/j.1460-2075.1993.tb05842.x
40 https://doi.org/10.1002/j.1460-2075.1994.tb06289.x
41 https://doi.org/10.1002/j.1460-2075.1996.tb01045.x
42 https://doi.org/10.1006/bbrc.1996.6047
43 https://doi.org/10.1006/geno.1996.0527
44 https://doi.org/10.1016/0092-8674(92)90098-w
45 https://doi.org/10.1016/0092-8674(93)90232-f
46 https://doi.org/10.1016/0092-8674(95)90534-0
47 https://doi.org/10.1016/0167-4889(94)90261-5
48 https://doi.org/10.1016/0968-0004(93)90031-h
49 https://doi.org/10.1016/s0092-8674(00)81236-2
50 https://doi.org/10.1016/s0092-8674(00)81274-x
51 https://doi.org/10.1016/s0092-8674(00)81840-1
52 https://doi.org/10.1016/s0092-8674(00)81841-3
53 https://doi.org/10.1016/s0092-8674(00)81872-3
54 https://doi.org/10.1016/s0092-8674(00)81896-6
55 https://doi.org/10.1016/s0140-6736(95)92779-4
56 https://doi.org/10.1016/s0960-9822(00)00087-7
57 https://doi.org/10.1021/bi9630974
58 https://doi.org/10.1073/pnas.89.23.11239
59 https://doi.org/10.1073/pnas.90.24.11713
60 https://doi.org/10.1073/pnas.90.9.4032
61 https://doi.org/10.1073/pnas.92.3.664
62 https://doi.org/10.1074/jbc.270.49.29189
63 https://doi.org/10.1074/jbc.270.8.3662
64 https://doi.org/10.1074/jbc.271.10.5317
65 https://doi.org/10.1074/jbc.271.11.5980
66 https://doi.org/10.1074/jbc.271.16.9287
67 https://doi.org/10.1074/jbc.271.17.10200
68 https://doi.org/10.1074/jbc.271.18.10583
69 https://doi.org/10.1074/jbc.271.20.11641
70 https://doi.org/10.1074/jbc.271.35.21353
71 https://doi.org/10.1074/jbc.272.17.11439
72 https://doi.org/10.1074/jbc.272.17.11663
73 https://doi.org/10.1074/jbc.272.4.2551
74 https://doi.org/10.1098/rstb.1996.0011
75 https://doi.org/10.1126/science.271.5249.665
76 https://doi.org/10.1126/science.275.5300.628
77 https://doi.org/10.1126/science.275.5300.661
78 https://doi.org/10.1126/science.7527156
79 https://doi.org/10.1126/science.7701324
80 https://doi.org/10.1126/science.8096088
81 https://doi.org/10.1126/science.8316835
82 https://doi.org/10.1128/mcb.14.10.6674
83 https://doi.org/10.1128/mcb.14.6.3577
84 https://doi.org/10.1128/mcb.15.8.4232
85 https://doi.org/10.1128/mcb.15.8.4453
86 https://doi.org/10.1128/mcb.16.5.2195
87 https://doi.org/10.1128/mcb.16.6.2857
88 https://doi.org/10.1128/mcb.16.6.3074
89 https://doi.org/10.1128/mcb.16.8.4147
90 https://doi.org/10.1128/mcb.17.3.1513
91 https://doi.org/10.1172/jci117936
92 https://doi.org/10.1172/jci118705
93 https://doi.org/10.1210/mend.11.2.9885
94 https://doi.org/10.2337/diabetes.43.11.1271
95 schema:datePublished 1998-05
96 schema:datePublishedReg 1998-05-01
97 schema:description New molecules discovered during the past ten years have created a rational framework to understand signalling transduction by a broad range of growth factors and cytokines, including insulin. Insulin action is initiated through the insulin receptor, a transmembrane glycoprotein with intrinsic protein tyrosine kinase activity. The tyrosine kinase mediates the insulin response through tyrosine phosphorylation of various cellular substrates, in particular the IRS-proteins. During insulin-stimulated tyrosine phosphorylation, the IRS-proteins mediate a broad biological response by binding and activating various enzymes or adapter molecules. Although we are far from a complete understanding of the insulin signalling system and its failure, enough pieces of the puzzle are falling into place that mechanism-based solutions to insulin resistance encountered with type II diabetes may soon be attainable.
98 schema:genre research_article
99 schema:inLanguage en
100 schema:isAccessibleForFree false
101 schema:isPartOf N87fed6a1cd064126b31bc91e084a1fce
102 Ne83845f3519d47b1bac559401713c085
103 sg:journal.1016672
104 schema:name The IRS-signalling system: A network of docking proteins that mediate insulin action
105 schema:pagination 3-11
106 schema:productId N221c1a17068a423286d39bc813ca9bf0
107 N223001e772bc4407ad7a524685bfe9df
108 N5cba6b7eb5b4493bbc510844da6106fb
109 Nb925ac458b8b4cee992ee6fd0b4180be
110 Nf9922196443e42d99140d24ec1e43e45
111 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003203012
112 https://doi.org/10.1023/a:1006806722619
113 schema:sdDatePublished 2019-04-10T23:21
114 schema:sdLicense https://scigraph.springernature.com/explorer/license/
115 schema:sdPublisher Nfe879d5cb68746a38ef5bf25358fbd7b
116 schema:url http://link.springer.com/10.1023/A:1006806722619
117 sgo:license sg:explorer/license/
118 sgo:sdDataset articles
119 rdf:type schema:ScholarlyArticle
120 N0f48c1259cc34603bf282a151325b35b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
121 schema:name Intracellular Signaling Peptides and Proteins
122 rdf:type schema:DefinedTerm
123 N173a3c6666de458e8094c2dfb7654c7c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
124 schema:name Insulin Receptor Substrate Proteins
125 rdf:type schema:DefinedTerm
126 N17f836587cbc4497b2a603c2fc2cb299 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
127 schema:name Receptor, Insulin
128 rdf:type schema:DefinedTerm
129 N221c1a17068a423286d39bc813ca9bf0 schema:name doi
130 schema:value 10.1023/a:1006806722619
131 rdf:type schema:PropertyValue
132 N223001e772bc4407ad7a524685bfe9df schema:name readcube_id
133 schema:value 0f41cdbb39cb51e2a873543388a6f6951195bb766afd73d408b5361156c2fe8b
134 rdf:type schema:PropertyValue
135 N3ed740b4bc9b41569ac75adaf9066487 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
136 schema:name Animals
137 rdf:type schema:DefinedTerm
138 N5cba6b7eb5b4493bbc510844da6106fb schema:name dimensions_id
139 schema:value pub.1003203012
140 rdf:type schema:PropertyValue
141 N624bc9c7b67c44bbba15cedf2cc54b45 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
142 schema:name RNA-Binding Proteins
143 rdf:type schema:DefinedTerm
144 N68b97df604964ec59c76e5ff7b51cfba schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
145 schema:name Phosphoproteins
146 rdf:type schema:DefinedTerm
147 N744d746125db4e5387061fcbaaf2db4d rdf:first sg:person.013274422527.22
148 rdf:rest rdf:nil
149 N7c113395e37b4a1dbeef217708ecb563 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
150 schema:name Insulin
151 rdf:type schema:DefinedTerm
152 N87fed6a1cd064126b31bc91e084a1fce schema:issueNumber 1-2
153 rdf:type schema:PublicationIssue
154 N8f19b4717d31470aa09fadabb01999bd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
155 schema:name DNA-Binding Proteins
156 rdf:type schema:DefinedTerm
157 Nb925ac458b8b4cee992ee6fd0b4180be schema:name nlm_unique_id
158 schema:value 0364456
159 rdf:type schema:PropertyValue
160 Nd1e1e23aebd54e9aa2b5594cf01cc735 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
161 schema:name Humans
162 rdf:type schema:DefinedTerm
163 Nd3056083d0ac45a9942b53fed64aa637 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
164 schema:name Adaptor Proteins, Signal Transducing
165 rdf:type schema:DefinedTerm
166 Ne401a20402634e848b8f854d174ae471 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
167 schema:name Signal Transduction
168 rdf:type schema:DefinedTerm
169 Ne83845f3519d47b1bac559401713c085 schema:volumeNumber 182
170 rdf:type schema:PublicationVolume
171 Nf9922196443e42d99140d24ec1e43e45 schema:name pubmed_id
172 schema:value 9609109
173 rdf:type schema:PropertyValue
174 Nfe879d5cb68746a38ef5bf25358fbd7b schema:name Springer Nature - SN SciGraph project
175 rdf:type schema:Organization
176 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
177 schema:name Biological Sciences
178 rdf:type schema:DefinedTerm
179 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
180 schema:name Biochemistry and Cell Biology
181 rdf:type schema:DefinedTerm
182 sg:grant.2493645 http://pending.schema.org/fundedItem sg:pub.10.1023/a:1006806722619
183 rdf:type schema:MonetaryGrant
184 sg:grant.2494482 http://pending.schema.org/fundedItem sg:pub.10.1023/a:1006806722619
185 rdf:type schema:MonetaryGrant
186 sg:grant.2627419 http://pending.schema.org/fundedItem sg:pub.10.1023/a:1006806722619
187 rdf:type schema:MonetaryGrant
188 sg:grant.2664872 http://pending.schema.org/fundedItem sg:pub.10.1023/a:1006806722619
189 rdf:type schema:MonetaryGrant
190 sg:journal.1016672 schema:issn 0300-8177
191 1573-4919
192 schema:name Molecular and Cellular Biochemistry
193 rdf:type schema:Periodical
194 sg:person.013274422527.22 schema:affiliation https://www.grid.ac/institutes/grid.38142.3c
195 schema:familyName White
196 schema:givenName Morris F.
197 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013274422527.22
198 rdf:type schema:Person
199 sg:pub.10.1038/318183a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025875577
200 https://doi.org/10.1038/318183a0
201 rdf:type schema:CreativeWork
202 sg:pub.10.1038/352073a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045276619
203 https://doi.org/10.1038/352073a0
204 rdf:type schema:CreativeWork
205 sg:pub.10.1038/363088a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012003451
206 https://doi.org/10.1038/363088a0
207 rdf:type schema:CreativeWork
208 sg:pub.10.1038/367474a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030955834
209 https://doi.org/10.1038/367474a0
210 rdf:type schema:CreativeWork
211 sg:pub.10.1038/372182a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046415369
212 https://doi.org/10.1038/372182a0
213 rdf:type schema:CreativeWork
214 sg:pub.10.1038/372186a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049271444
215 https://doi.org/10.1038/372186a0
216 rdf:type schema:CreativeWork
217 sg:pub.10.1038/373573a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008518821
218 https://doi.org/10.1038/373573a0
219 rdf:type schema:CreativeWork
220 sg:pub.10.1038/377173a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022346115
221 https://doi.org/10.1038/377173a0
222 rdf:type schema:CreativeWork
223 sg:pub.10.1038/378785a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042289302
224 https://doi.org/10.1038/378785a0
225 rdf:type schema:CreativeWork
226 sg:pub.10.1038/379277a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004867089
227 https://doi.org/10.1038/379277a0
228 rdf:type schema:CreativeWork
229 sg:pub.10.1038/379560a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043414343
230 https://doi.org/10.1038/379560a0
231 rdf:type schema:CreativeWork
232 sg:pub.10.1038/380075a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029942479
233 https://doi.org/10.1038/380075a0
234 rdf:type schema:CreativeWork
235 https://app.dimensions.ai/details/publication/pub.1075455459 schema:CreativeWork
236 https://app.dimensions.ai/details/publication/pub.1082393661 schema:CreativeWork
237 https://app.dimensions.ai/details/publication/pub.1082397758 schema:CreativeWork
238 https://app.dimensions.ai/details/publication/pub.1082467503 schema:CreativeWork
239 https://app.dimensions.ai/details/publication/pub.1082597216 schema:CreativeWork
240 https://app.dimensions.ai/details/publication/pub.1082619572 schema:CreativeWork
241 https://app.dimensions.ai/details/publication/pub.1082653590 schema:CreativeWork
242 https://app.dimensions.ai/details/publication/pub.1082653592 schema:CreativeWork
243 https://app.dimensions.ai/details/publication/pub.1082783969 schema:CreativeWork
244 https://app.dimensions.ai/details/publication/pub.1082835552 schema:CreativeWork
245 https://app.dimensions.ai/details/publication/pub.1082839940 schema:CreativeWork
246 https://app.dimensions.ai/details/publication/pub.1082888489 schema:CreativeWork
247 https://doi.org/10.1002/j.1460-2075.1993.tb05842.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1082829517
248 rdf:type schema:CreativeWork
249 https://doi.org/10.1002/j.1460-2075.1994.tb06289.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1082752641
250 rdf:type schema:CreativeWork
251 https://doi.org/10.1002/j.1460-2075.1996.tb01045.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1083023835
252 rdf:type schema:CreativeWork
253 https://doi.org/10.1006/bbrc.1996.6047 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033814329
254 rdf:type schema:CreativeWork
255 https://doi.org/10.1006/geno.1996.0527 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017641030
256 rdf:type schema:CreativeWork
257 https://doi.org/10.1016/0092-8674(92)90098-w schema:sameAs https://app.dimensions.ai/details/publication/pub.1013048571
258 rdf:type schema:CreativeWork
259 https://doi.org/10.1016/0092-8674(93)90232-f schema:sameAs https://app.dimensions.ai/details/publication/pub.1047403207
260 rdf:type schema:CreativeWork
261 https://doi.org/10.1016/0092-8674(95)90534-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046701590
262 rdf:type schema:CreativeWork
263 https://doi.org/10.1016/0167-4889(94)90261-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048178823
264 rdf:type schema:CreativeWork
265 https://doi.org/10.1016/0968-0004(93)90031-h schema:sameAs https://app.dimensions.ai/details/publication/pub.1021057942
266 rdf:type schema:CreativeWork
267 https://doi.org/10.1016/s0092-8674(00)81236-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044381040
268 rdf:type schema:CreativeWork
269 https://doi.org/10.1016/s0092-8674(00)81274-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1052346632
270 rdf:type schema:CreativeWork
271 https://doi.org/10.1016/s0092-8674(00)81840-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021110000
272 rdf:type schema:CreativeWork
273 https://doi.org/10.1016/s0092-8674(00)81841-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029007273
274 rdf:type schema:CreativeWork
275 https://doi.org/10.1016/s0092-8674(00)81872-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012374589
276 rdf:type schema:CreativeWork
277 https://doi.org/10.1016/s0092-8674(00)81896-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033103168
278 rdf:type schema:CreativeWork
279 https://doi.org/10.1016/s0140-6736(95)92779-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003277582
280 rdf:type schema:CreativeWork
281 https://doi.org/10.1016/s0960-9822(00)00087-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044470864
282 rdf:type schema:CreativeWork
283 https://doi.org/10.1021/bi9630974 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055213374
284 rdf:type schema:CreativeWork
285 https://doi.org/10.1073/pnas.89.23.11239 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028916365
286 rdf:type schema:CreativeWork
287 https://doi.org/10.1073/pnas.90.24.11713 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045670198
288 rdf:type schema:CreativeWork
289 https://doi.org/10.1073/pnas.90.9.4032 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000550130
290 rdf:type schema:CreativeWork
291 https://doi.org/10.1073/pnas.92.3.664 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049854353
292 rdf:type schema:CreativeWork
293 https://doi.org/10.1074/jbc.270.49.29189 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037488975
294 rdf:type schema:CreativeWork
295 https://doi.org/10.1074/jbc.270.8.3662 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033744443
296 rdf:type schema:CreativeWork
297 https://doi.org/10.1074/jbc.271.10.5317 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046152080
298 rdf:type schema:CreativeWork
299 https://doi.org/10.1074/jbc.271.11.5980 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014169912
300 rdf:type schema:CreativeWork
301 https://doi.org/10.1074/jbc.271.16.9287 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014625481
302 rdf:type schema:CreativeWork
303 https://doi.org/10.1074/jbc.271.17.10200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030074808
304 rdf:type schema:CreativeWork
305 https://doi.org/10.1074/jbc.271.18.10583 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042649232
306 rdf:type schema:CreativeWork
307 https://doi.org/10.1074/jbc.271.20.11641 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013529886
308 rdf:type schema:CreativeWork
309 https://doi.org/10.1074/jbc.271.35.21353 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002684494
310 rdf:type schema:CreativeWork
311 https://doi.org/10.1074/jbc.272.17.11439 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047223115
312 rdf:type schema:CreativeWork
313 https://doi.org/10.1074/jbc.272.17.11663 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012647919
314 rdf:type schema:CreativeWork
315 https://doi.org/10.1074/jbc.272.4.2551 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006696264
316 rdf:type schema:CreativeWork
317 https://doi.org/10.1098/rstb.1996.0011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051309270
318 rdf:type schema:CreativeWork
319 https://doi.org/10.1126/science.271.5249.665 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062552146
320 rdf:type schema:CreativeWork
321 https://doi.org/10.1126/science.275.5300.628 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062555644
322 rdf:type schema:CreativeWork
323 https://doi.org/10.1126/science.275.5300.661 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062555654
324 rdf:type schema:CreativeWork
325 https://doi.org/10.1126/science.7527156 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062647434
326 rdf:type schema:CreativeWork
327 https://doi.org/10.1126/science.7701324 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062648976
328 rdf:type schema:CreativeWork
329 https://doi.org/10.1126/science.8096088 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062652249
330 rdf:type schema:CreativeWork
331 https://doi.org/10.1126/science.8316835 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062654639
332 rdf:type schema:CreativeWork
333 https://doi.org/10.1128/mcb.14.10.6674 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034251442
334 rdf:type schema:CreativeWork
335 https://doi.org/10.1128/mcb.14.6.3577 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049809042
336 rdf:type schema:CreativeWork
337 https://doi.org/10.1128/mcb.15.8.4232 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031140582
338 rdf:type schema:CreativeWork
339 https://doi.org/10.1128/mcb.15.8.4453 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052321072
340 rdf:type schema:CreativeWork
341 https://doi.org/10.1128/mcb.16.5.2195 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041494890
342 rdf:type schema:CreativeWork
343 https://doi.org/10.1128/mcb.16.6.2857 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006424023
344 rdf:type schema:CreativeWork
345 https://doi.org/10.1128/mcb.16.6.3074 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037306349
346 rdf:type schema:CreativeWork
347 https://doi.org/10.1128/mcb.16.8.4147 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053538402
348 rdf:type schema:CreativeWork
349 https://doi.org/10.1128/mcb.17.3.1513 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011983895
350 rdf:type schema:CreativeWork
351 https://doi.org/10.1172/jci117936 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002666005
352 rdf:type schema:CreativeWork
353 https://doi.org/10.1172/jci118705 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011763092
354 rdf:type schema:CreativeWork
355 https://doi.org/10.1210/mend.11.2.9885 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064331421
356 rdf:type schema:CreativeWork
357 https://doi.org/10.2337/diabetes.43.11.1271 schema:sameAs https://app.dimensions.ai/details/publication/pub.1070742700
358 rdf:type schema:CreativeWork
359 https://www.grid.ac/institutes/grid.38142.3c schema:alternateName Harvard University
360 schema:name Research Division, Joslin Diabetes Center and the Graduate Program in Biomedical and Biological Sciences, Harvard Medical School, 02215, Boston, MA, USA
361 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...