Vascular Permeability Factor Expression in Cerebellar Hemangioblastomas: Correlation with Tumor-associated Cysts View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1999-01

AUTHORS

Jesús Vaquero, Mercedes Zurita, Santiago Oya, Santiago Coca, Clara Salas

ABSTRACT

The presence of vascular endothelial growth/permeability factor (VEG/PF) has been studied in histological specimens from a series of 16 cerebellar hemangioblastomas. In this series, the tumors were classified as presenting a macroscopic solid pattern (4 cases), a mainly solid pattern with macroscopic cysts (4 cases) or a mainly cystic pattern (8 cases). Solid tumors showed a low degree (75% of cases) or moderate degree (25% of cases) of VEG/PF positivity. The mainly solid tumors containing macroscopic cysts showed a moderate degree (50% of cases) or high degree (50% of cases) of VEG/PF positivity. Nevertheless, mainly cystic hemangioblastomas showed a high degree (87.5% of cases) or moderate degree (12.5% of cases) of VEG/PF positivity. These findings suggest that the predominance of a cystic or solid macroscopic appearance of cerebellar hemangioblastomas may be influenced by the degree of VEG/PF expression within the tumor tissue. More... »

PAGES

3-7

Identifiers

URI

http://scigraph.springernature.com/pub.10.1023/a:1006121002210

DOI

http://dx.doi.org/10.1023/a:1006121002210

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1021008703

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/10222417


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