Phase II study of vinorelbine and ifosfamide in anthtracycline resistent metastatic breast cancer View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1997-01

AUTHORS

P. Pronzato, P. Queirolo, M. Landucci, F. Vaira, A. Vigani, M. Gipponi, F. Cafiero

ABSTRACT

The new combination of ifosfamide and vinorelbine was evaluated in a phase II study of patients with metastatic breast cancer. All the patients had evaluable or measurable lesions resistant to the combination of cyclophosphamide, epidoxorubicin and 5-fluorouracil. Out of 25 patients entered the trial, 7 achieved an objective response (28%) (95% C.I. 12-49.3). Ten patients (40%) experienced stable disease and the remaining patients (30%) progressive disease. The median time to progression was 4 months (range 2-12+). The activity of the ifosfamide-vinorelbine combination has been demonstrated and the toxicity was acceptable. More... »

PAGES

183-186

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1023/a:1005720431557

DOI

http://dx.doi.org/10.1023/a:1005720431557

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1026141813

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/9138607


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