Ontology type: schema:ScholarlyArticle
1998-09
AUTHORSDaï Kitamoto, Hiroshi Yanagishita, Kenji Haraya, Hiroko K. Kitamoto
ABSTRACTInhibitors of β-oxidation on the synthesis of glycolipid biosurfactant, mannosylerythritol lipid (MEL), were used to clarify the fatty acid metabolism of MEL in Candida antarctica. 2-Bromooctanoic acid drastically inhibited the lipid synthesis under growing- and resting-cell conditions; moreover, the degree of the inhibition increased along with increases in both the inhibitor concentration and the chain-length of the fatty acid substrate used. These results clearly provide additional support for the essential contribution of the mammalian type of 'chain-shortening pathway' (partial β-oxidation) to the biosynthesis of the extracellular glycolipids. © Rapid Science Ltd. 1998 More... »
PAGES813-818
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DOIhttp://dx.doi.org/10.1023/a:1005347022247
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