Clinical Trials Offshored: On Private Sector Science and Public Health View Full Text


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Article Info

DATE

2007-03

AUTHORS

Adriana Petryna

ABSTRACT

This article addresses the offshoring of clinical trials to middle- and low-income countries, and the complicated ways in which they have become integral to public health and quality of care in these contexts. I focus on the operations of United States-based contract research organizations (CROs), which make up a specialized global industry focusing on the recruitment of human subjects and investigators; they are key players in an outsourced world of clinical development ‘service providers’. To get an on-the-ground understanding of the offshored clinical trial, I worked with regulators, health services administrators, and research clinicians in Eastern Europe and Latin America, two clinical trial market ‘growth regions’. By addressing the strategies of evidence-making that inform clinical trial offshoring, this article identifies the context-specific calculations by which experimental groups are being identified. It also addresses aspects of the clinical trial operational model, in which the failure to predict safety outcomes or a paradigm of expected failure is being exported along with the offshored trial. By highlighting the uncertainties of clinical research, this article points to gaps in systems of human protection as it considers new forms of accountability in private sector science and public health. More... »

PAGES

21-40

References to SciGraph publications

  • 2001-03. Technology and Affect: HIV/AIDS Testing in Brazil in CULTURE, MEDICINE, AND PSYCHIATRY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1017/s1745855207005030

    DOI

    http://dx.doi.org/10.1017/s1745855207005030

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