Epigallocatechin gallate accelerates healing of indomethacin-induced stomach ulcers in mice View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2011-03

AUTHORS

Biplab Adhikary, Sudhir K. Yadav, Sandip K. Bandyopadhyay, Subrata Chattopadhyay

ABSTRACT

Management of the gastric toxicity of non-steroidal anti-inflammatory drugs (NSAIDs) remains a crucial problem because the commercially available drugs have side effects and are often expensive. Therefore, we examined the potential of the green tea-derived polyphenol epigallocatechin gallate (EGCG) to treat indomethacin-induced stomach ulcers in mice. Administration of indomethacin (18 mg/kg, po) to mice induced ulceration in the glandular portion of the gastric mucosa, accompanied by increased lipid peroxidation (LPO) and protein oxidation and reductions in thiol defense, mucin, cyclooxygenase (COX) expression and prostaglandin (PG) synthesis in the gastric tissues. Daily oral administration of EGCG (2 mg/kg) or omeprazole (3 mg/kg) for 3 days produced similar (≈ 72-75%, p < 0.001) beneficial effects on the acute gastric ulceration. Treatment with the test samples partially reversed all the adverse oxidative effects of indomethacin. In addition, EGCG, but not omeprazole, enhanced expression of the COX isoforms and PG synthesis. The results suggest that the non-toxic and inexpensive tea polyphenol EGCG may be an excellent candidate for further evaluation as a potent anti-ulcer drug. More... »

PAGES

527-536

Identifiers

URI

http://scigraph.springernature.com/pub.10.1016/s1734-1140(11)70519-9

DOI

http://dx.doi.org/10.1016/s1734-1140(11)70519-9

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1036213136

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/21602608


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1115", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Pharmacology and Pharmaceutical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Anti-Inflammatory Agents, Non-Steroidal", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Anti-Ulcer Agents", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Antioxidants", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Catechin", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Disease Models, Animal", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Gastric Mucosa", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Indomethacin", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Lipid Peroxidation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mice", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Omeprazole", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Oxidative Stress", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Stomach Ulcer", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Tea", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Department of Biochemistry, Dr. B.C. Roy Post Graduate Institute of Basic Medical Sciences & IPGME&R, 244B, Acharya Jagadish Chandra Bose Road, Kolkata \u2013 700 020, India", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Department of Biochemistry, Dr. B.C. Roy Post Graduate Institute of Basic Medical Sciences & IPGME&R, 244B, Acharya Jagadish Chandra Bose Road, Kolkata \u2013 700 020, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Adhikary", 
        "givenName": "Biplab", 
        "id": "sg:person.01031313237.03", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01031313237.03"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Biochemistry, Dr. B.C. Roy Post Graduate Institute of Basic Medical Sciences & IPGME&R, 244B, Acharya Jagadish Chandra Bose Road, Kolkata \u2013 700 020, India", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Department of Biochemistry, Dr. B.C. Roy Post Graduate Institute of Basic Medical Sciences & IPGME&R, 244B, Acharya Jagadish Chandra Bose Road, Kolkata \u2013 700 020, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Yadav", 
        "givenName": "Sudhir K.", 
        "id": "sg:person.0732615326.07", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0732615326.07"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Biochemistry, Dr. B.C. Roy Post Graduate Institute of Basic Medical Sciences & IPGME&R, 244B, Acharya Jagadish Chandra Bose Road, Kolkata \u2013 700 020, India", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Department of Biochemistry, Dr. B.C. Roy Post Graduate Institute of Basic Medical Sciences & IPGME&R, 244B, Acharya Jagadish Chandra Bose Road, Kolkata \u2013 700 020, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bandyopadhyay", 
        "givenName": "Sandip K.", 
        "id": "sg:person.01245022565.07", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01245022565.07"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Bio-Organic Division, Bhabha Atomic Research Centre, Mumbai \u2013 400 085, India", 
          "id": "http://www.grid.ac/institutes/grid.418304.a", 
          "name": [
            "Bio-Organic Division, Bhabha Atomic Research Centre, Mumbai \u2013 400 085, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chattopadhyay", 
        "givenName": "Subrata", 
        "id": "sg:person.0704030103.39", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0704030103.39"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/bf02265120", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051431674", 
          "https://doi.org/10.1007/bf02265120"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1111/j.1572-0241.2005.41833.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040140032", 
          "https://doi.org/10.1111/j.1572-0241.2005.41833.x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/234304a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013373319", 
          "https://doi.org/10.1038/234304a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1023/a:1026608020133", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044307311", 
          "https://doi.org/10.1023/a:1026608020133"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00109-003-0479-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010078486", 
          "https://doi.org/10.1007/s00109-003-0479-y"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/70995", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035528462", 
          "https://doi.org/10.1038/70995"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1023/a:1026668816189", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049696761", 
          "https://doi.org/10.1023/a:1026668816189"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ncpgasthep0610", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002023580", 
          "https://doi.org/10.1038/ncpgasthep0610"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2011-03", 
    "datePublishedReg": "2011-03-01", 
    "description": "Management of the gastric toxicity of non-steroidal anti-inflammatory drugs (NSAIDs) remains a crucial problem because the commercially available drugs have side effects and are often expensive. Therefore, we examined the potential of the green tea-derived polyphenol epigallocatechin gallate (EGCG) to treat indomethacin-induced stomach ulcers in mice. Administration of indomethacin (18 mg/kg, po) to mice induced ulceration in the glandular portion of the gastric mucosa, accompanied by increased lipid peroxidation (LPO) and protein oxidation and reductions in thiol defense, mucin, cyclooxygenase (COX) expression and prostaglandin (PG) synthesis in the gastric tissues. Daily oral administration of EGCG (2 mg/kg) or omeprazole (3 mg/kg) for 3 days produced similar (\u2248 72-75%, p < 0.001) beneficial effects on the acute gastric ulceration. Treatment with the test samples partially reversed all the adverse oxidative effects of indomethacin. In addition, EGCG, but not omeprazole, enhanced expression of the COX isoforms and PG synthesis. The results suggest that the non-toxic and inexpensive tea polyphenol EGCG may be an excellent candidate for further evaluation as a potent anti-ulcer drug.", 
    "genre": "article", 
    "id": "sg:pub.10.1016/s1734-1140(11)70519-9", 
    "inLanguage": "en", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1034671", 
        "issn": [
          "1734-1140", 
          "2299-5684"
        ], 
        "name": "Pharmacological Reports", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "2", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "63"
      }
    ], 
    "keywords": [
      "non-steroidal anti-inflammatory drugs", 
      "stomach ulcers", 
      "healing of indomethacin", 
      "anti-inflammatory drugs", 
      "administration of indomethacin", 
      "green tea-derived polyphenol", 
      "acute gastric ulceration", 
      "anti-ulcer drugs", 
      "lipid peroxidation", 
      "daily oral administration", 
      "potent anti-ulcer drug", 
      "tea-derived polyphenols", 
      "tea polyphenol EGCG", 
      "adverse oxidative effects", 
      "gastric toxicity", 
      "gastric ulceration", 
      "Induced Ulceration", 
      "gastric mucosa", 
      "side effects", 
      "prostaglandin synthesis", 
      "oral administration", 
      "cyclooxygenase expression", 
      "COX isoforms", 
      "available drugs", 
      "gastric tissue", 
      "further evaluation", 
      "indomethacin", 
      "polyphenol EGCG", 
      "beneficial effects", 
      "glandular portion", 
      "PG synthesis", 
      "enhanced expression", 
      "ulceration", 
      "ulcers", 
      "drugs", 
      "omeprazole", 
      "epigallocatechin gallate", 
      "mice", 
      "administration", 
      "EGCG", 
      "oxidative effects", 
      "protein oxidation", 
      "mucosa", 
      "expression", 
      "healing", 
      "treatment", 
      "gallate", 
      "peroxidation", 
      "mucin", 
      "effect", 
      "tissue", 
      "toxicity", 
      "days", 
      "isoforms", 
      "polyphenols", 
      "management", 
      "evaluation", 
      "reduction", 
      "defense", 
      "excellent candidate", 
      "candidates", 
      "synthesis", 
      "addition", 
      "portion", 
      "samples", 
      "potential", 
      "results", 
      "oxidation", 
      "test samples", 
      "problem", 
      "crucial problem", 
      "thiol defense", 
      "inexpensive tea polyphenol EGCG"
    ], 
    "name": "Epigallocatechin gallate accelerates healing of indomethacin-induced stomach ulcers in mice", 
    "pagination": "527-536", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1036213136"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1016/s1734-1140(11)70519-9"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "21602608"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1016/s1734-1140(11)70519-9", 
      "https://app.dimensions.ai/details/publication/pub.1036213136"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-01-01T18:26", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220101/entities/gbq_results/article/article_553.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1016/s1734-1140(11)70519-9"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1016/s1734-1140(11)70519-9'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1016/s1734-1140(11)70519-9'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1016/s1734-1140(11)70519-9'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1016/s1734-1140(11)70519-9'


 

This table displays all metadata directly associated to this object as RDF triples.

251 TRIPLES      22 PREDICATES      123 URIs      107 LITERALS      22 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1016/s1734-1140(11)70519-9 schema:about N0971dcb61f4649d1861ca5baa6950b4f
2 N4fcd5574c8ee4fef87ac0a2779981366
3 N53c43f9f9b30465aaff3765cdd6ef57f
4 N5eb7a03f10fc402aa29fbaffef53b5a5
5 N7de9b05e6fef4b5e95ec7ca8ddbb6c24
6 N8d4363a496294cc8898dced9dc923541
7 N995ced97ffae413fb0ce32bbd1a07b19
8 Na08d7525b2ef4903b83d4f071ed27196
9 Na3228194aa964e8fbb2ebc4089049bfd
10 Naeccbbe4e6b440be871398ebda82afb9
11 Nb596f9853556465c86389f1a2ba5d91e
12 Nd297d5e7d1e3467d840b8e06ced8c1e3
13 Nf140bd534652424cbc4234dffa4e48f6
14 Nf3cbcdc40cb8497a889a0f4578035df5
15 Nfaa331632a5f4117897ec276d646ed16
16 anzsrc-for:11
17 anzsrc-for:1115
18 schema:author Nedca81b6a4414ea2b78befcb40adb606
19 schema:citation sg:pub.10.1007/bf02265120
20 sg:pub.10.1007/s00109-003-0479-y
21 sg:pub.10.1023/a:1026608020133
22 sg:pub.10.1023/a:1026668816189
23 sg:pub.10.1038/234304a0
24 sg:pub.10.1038/70995
25 sg:pub.10.1038/ncpgasthep0610
26 sg:pub.10.1111/j.1572-0241.2005.41833.x
27 schema:datePublished 2011-03
28 schema:datePublishedReg 2011-03-01
29 schema:description Management of the gastric toxicity of non-steroidal anti-inflammatory drugs (NSAIDs) remains a crucial problem because the commercially available drugs have side effects and are often expensive. Therefore, we examined the potential of the green tea-derived polyphenol epigallocatechin gallate (EGCG) to treat indomethacin-induced stomach ulcers in mice. Administration of indomethacin (18 mg/kg, po) to mice induced ulceration in the glandular portion of the gastric mucosa, accompanied by increased lipid peroxidation (LPO) and protein oxidation and reductions in thiol defense, mucin, cyclooxygenase (COX) expression and prostaglandin (PG) synthesis in the gastric tissues. Daily oral administration of EGCG (2 mg/kg) or omeprazole (3 mg/kg) for 3 days produced similar (≈ 72-75%, p < 0.001) beneficial effects on the acute gastric ulceration. Treatment with the test samples partially reversed all the adverse oxidative effects of indomethacin. In addition, EGCG, but not omeprazole, enhanced expression of the COX isoforms and PG synthesis. The results suggest that the non-toxic and inexpensive tea polyphenol EGCG may be an excellent candidate for further evaluation as a potent anti-ulcer drug.
30 schema:genre article
31 schema:inLanguage en
32 schema:isAccessibleForFree false
33 schema:isPartOf N34b02250df664b8b88b7b48e8efed438
34 N64db56bba8fd462a854fb5e691f51db6
35 sg:journal.1034671
36 schema:keywords COX isoforms
37 EGCG
38 Induced Ulceration
39 PG synthesis
40 acute gastric ulceration
41 addition
42 administration
43 administration of indomethacin
44 adverse oxidative effects
45 anti-inflammatory drugs
46 anti-ulcer drugs
47 available drugs
48 beneficial effects
49 candidates
50 crucial problem
51 cyclooxygenase expression
52 daily oral administration
53 days
54 defense
55 drugs
56 effect
57 enhanced expression
58 epigallocatechin gallate
59 evaluation
60 excellent candidate
61 expression
62 further evaluation
63 gallate
64 gastric mucosa
65 gastric tissue
66 gastric toxicity
67 gastric ulceration
68 glandular portion
69 green tea-derived polyphenol
70 healing
71 healing of indomethacin
72 indomethacin
73 inexpensive tea polyphenol EGCG
74 isoforms
75 lipid peroxidation
76 management
77 mice
78 mucin
79 mucosa
80 non-steroidal anti-inflammatory drugs
81 omeprazole
82 oral administration
83 oxidation
84 oxidative effects
85 peroxidation
86 polyphenol EGCG
87 polyphenols
88 portion
89 potent anti-ulcer drug
90 potential
91 problem
92 prostaglandin synthesis
93 protein oxidation
94 reduction
95 results
96 samples
97 side effects
98 stomach ulcers
99 synthesis
100 tea polyphenol EGCG
101 tea-derived polyphenols
102 test samples
103 thiol defense
104 tissue
105 toxicity
106 treatment
107 ulceration
108 ulcers
109 schema:name Epigallocatechin gallate accelerates healing of indomethacin-induced stomach ulcers in mice
110 schema:pagination 527-536
111 schema:productId N0059e942085f4705a46f139befb14e65
112 Nad59d411385a4104a03b557f63f5887a
113 Ncca59a52f9d24a58a13b83c480bcea36
114 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036213136
115 https://doi.org/10.1016/s1734-1140(11)70519-9
116 schema:sdDatePublished 2022-01-01T18:26
117 schema:sdLicense https://scigraph.springernature.com/explorer/license/
118 schema:sdPublisher N154976d273f54a598dc91f839e50deda
119 schema:url https://doi.org/10.1016/s1734-1140(11)70519-9
120 sgo:license sg:explorer/license/
121 sgo:sdDataset articles
122 rdf:type schema:ScholarlyArticle
123 N0059e942085f4705a46f139befb14e65 schema:name dimensions_id
124 schema:value pub.1036213136
125 rdf:type schema:PropertyValue
126 N0971dcb61f4649d1861ca5baa6950b4f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
127 schema:name Tea
128 rdf:type schema:DefinedTerm
129 N154976d273f54a598dc91f839e50deda schema:name Springer Nature - SN SciGraph project
130 rdf:type schema:Organization
131 N34b02250df664b8b88b7b48e8efed438 schema:issueNumber 2
132 rdf:type schema:PublicationIssue
133 N3c9a738e66ba4d27ab22ec593b0a2025 rdf:first sg:person.01245022565.07
134 rdf:rest N82fef9066b464aa7bbdda4b0219756e7
135 N4fcd5574c8ee4fef87ac0a2779981366 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
136 schema:name Gastric Mucosa
137 rdf:type schema:DefinedTerm
138 N53c43f9f9b30465aaff3765cdd6ef57f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
139 schema:name Mice
140 rdf:type schema:DefinedTerm
141 N5eb7a03f10fc402aa29fbaffef53b5a5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
142 schema:name Omeprazole
143 rdf:type schema:DefinedTerm
144 N64db56bba8fd462a854fb5e691f51db6 schema:volumeNumber 63
145 rdf:type schema:PublicationVolume
146 N7de9b05e6fef4b5e95ec7ca8ddbb6c24 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
147 schema:name Male
148 rdf:type schema:DefinedTerm
149 N82fef9066b464aa7bbdda4b0219756e7 rdf:first sg:person.0704030103.39
150 rdf:rest rdf:nil
151 N8d4363a496294cc8898dced9dc923541 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
152 schema:name Stomach Ulcer
153 rdf:type schema:DefinedTerm
154 N995ced97ffae413fb0ce32bbd1a07b19 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
155 schema:name Anti-Ulcer Agents
156 rdf:type schema:DefinedTerm
157 Na08d7525b2ef4903b83d4f071ed27196 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
158 schema:name Animals
159 rdf:type schema:DefinedTerm
160 Na3228194aa964e8fbb2ebc4089049bfd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
161 schema:name Catechin
162 rdf:type schema:DefinedTerm
163 Na7244a5c49e2473f976ff203fe2169b4 rdf:first sg:person.0732615326.07
164 rdf:rest N3c9a738e66ba4d27ab22ec593b0a2025
165 Nad59d411385a4104a03b557f63f5887a schema:name pubmed_id
166 schema:value 21602608
167 rdf:type schema:PropertyValue
168 Naeccbbe4e6b440be871398ebda82afb9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
169 schema:name Antioxidants
170 rdf:type schema:DefinedTerm
171 Nb596f9853556465c86389f1a2ba5d91e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
172 schema:name Anti-Inflammatory Agents, Non-Steroidal
173 rdf:type schema:DefinedTerm
174 Ncca59a52f9d24a58a13b83c480bcea36 schema:name doi
175 schema:value 10.1016/s1734-1140(11)70519-9
176 rdf:type schema:PropertyValue
177 Nd297d5e7d1e3467d840b8e06ced8c1e3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
178 schema:name Indomethacin
179 rdf:type schema:DefinedTerm
180 Nedca81b6a4414ea2b78befcb40adb606 rdf:first sg:person.01031313237.03
181 rdf:rest Na7244a5c49e2473f976ff203fe2169b4
182 Nf140bd534652424cbc4234dffa4e48f6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
183 schema:name Disease Models, Animal
184 rdf:type schema:DefinedTerm
185 Nf3cbcdc40cb8497a889a0f4578035df5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
186 schema:name Lipid Peroxidation
187 rdf:type schema:DefinedTerm
188 Nfaa331632a5f4117897ec276d646ed16 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
189 schema:name Oxidative Stress
190 rdf:type schema:DefinedTerm
191 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
192 schema:name Medical and Health Sciences
193 rdf:type schema:DefinedTerm
194 anzsrc-for:1115 schema:inDefinedTermSet anzsrc-for:
195 schema:name Pharmacology and Pharmaceutical Sciences
196 rdf:type schema:DefinedTerm
197 sg:journal.1034671 schema:issn 1734-1140
198 2299-5684
199 schema:name Pharmacological Reports
200 schema:publisher Springer Nature
201 rdf:type schema:Periodical
202 sg:person.01031313237.03 schema:affiliation grid-institutes:None
203 schema:familyName Adhikary
204 schema:givenName Biplab
205 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01031313237.03
206 rdf:type schema:Person
207 sg:person.01245022565.07 schema:affiliation grid-institutes:None
208 schema:familyName Bandyopadhyay
209 schema:givenName Sandip K.
210 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01245022565.07
211 rdf:type schema:Person
212 sg:person.0704030103.39 schema:affiliation grid-institutes:grid.418304.a
213 schema:familyName Chattopadhyay
214 schema:givenName Subrata
215 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0704030103.39
216 rdf:type schema:Person
217 sg:person.0732615326.07 schema:affiliation grid-institutes:None
218 schema:familyName Yadav
219 schema:givenName Sudhir K.
220 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0732615326.07
221 rdf:type schema:Person
222 sg:pub.10.1007/bf02265120 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051431674
223 https://doi.org/10.1007/bf02265120
224 rdf:type schema:CreativeWork
225 sg:pub.10.1007/s00109-003-0479-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1010078486
226 https://doi.org/10.1007/s00109-003-0479-y
227 rdf:type schema:CreativeWork
228 sg:pub.10.1023/a:1026608020133 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044307311
229 https://doi.org/10.1023/a:1026608020133
230 rdf:type schema:CreativeWork
231 sg:pub.10.1023/a:1026668816189 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049696761
232 https://doi.org/10.1023/a:1026668816189
233 rdf:type schema:CreativeWork
234 sg:pub.10.1038/234304a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013373319
235 https://doi.org/10.1038/234304a0
236 rdf:type schema:CreativeWork
237 sg:pub.10.1038/70995 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035528462
238 https://doi.org/10.1038/70995
239 rdf:type schema:CreativeWork
240 sg:pub.10.1038/ncpgasthep0610 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002023580
241 https://doi.org/10.1038/ncpgasthep0610
242 rdf:type schema:CreativeWork
243 sg:pub.10.1111/j.1572-0241.2005.41833.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1040140032
244 https://doi.org/10.1111/j.1572-0241.2005.41833.x
245 rdf:type schema:CreativeWork
246 grid-institutes:None schema:alternateName Department of Biochemistry, Dr. B.C. Roy Post Graduate Institute of Basic Medical Sciences & IPGME&R, 244B, Acharya Jagadish Chandra Bose Road, Kolkata – 700 020, India
247 schema:name Department of Biochemistry, Dr. B.C. Roy Post Graduate Institute of Basic Medical Sciences & IPGME&R, 244B, Acharya Jagadish Chandra Bose Road, Kolkata – 700 020, India
248 rdf:type schema:Organization
249 grid-institutes:grid.418304.a schema:alternateName Bio-Organic Division, Bhabha Atomic Research Centre, Mumbai – 400 085, India
250 schema:name Bio-Organic Division, Bhabha Atomic Research Centre, Mumbai – 400 085, India
251 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...