Quantitative proteomic analysis of chromatin-associated factors View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2003-07-01

AUTHORS

Yuzuru Shiio, Robert N. Eisenman, Eugene C. Yi, Sam Donohoe, David R. Goodlett, Ruedi Aebersold

ABSTRACT

A method to identify and quantify chromatin-associated proteins has been developed and applied to the analysis of changes in chromatin-associated proteins induced by Myc oncoprotein expression in human B lymphocytes. Chromatin-enriched fractions were isolated by differential detergent/salt extraction and analyzed by ICAT reagent labeling, multi-dimensional chromatography and tandem mass spectrometry. Many known chromatin-associated regulatory factors were identified and quantified. The method will be widely applicable to various biological systems and reveal changes in chromatin-associated regulatory factors that underlie biological phenomena. More... »

PAGES

696-703

Identifiers

URI

http://scigraph.springernature.com/pub.10.1016/s1044-0305(03)00204-6

DOI

http://dx.doi.org/10.1016/s1044-0305(03)00204-6

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1020708456

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/12837591


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/03", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Chemical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0301", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Analytical Chemistry", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "B-Lymphocytes", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cell Line", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Chromatin", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Chromosomal Proteins, Non-Histone", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genes, myc", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Nuclear Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Proteome", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Up-Regulation", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Institute for Systems Biology, 98103, Seattle, WA", 
          "id": "http://www.grid.ac/institutes/grid.64212.33", 
          "name": [
            "Division of Basic Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N. A2-025, 98109-1024, Seattle, WA, USA", 
            "Institute for Systems Biology, 98103, Seattle, WA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Shiio", 
        "givenName": "Yuzuru", 
        "id": "sg:person.0673221741.23", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0673221741.23"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Division of Basic Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N. A2-025, 98109-1024, Seattle, WA, USA", 
          "id": "http://www.grid.ac/institutes/grid.270240.3", 
          "name": [
            "Division of Basic Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N. A2-025, 98109-1024, Seattle, WA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Eisenman", 
        "givenName": "Robert N.", 
        "id": "sg:person.01256252712.88", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01256252712.88"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute for Systems Biology, Seattle, Washington, USA", 
          "id": "http://www.grid.ac/institutes/grid.64212.33", 
          "name": [
            "Institute for Systems Biology, Seattle, Washington, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Yi", 
        "givenName": "Eugene C.", 
        "id": "sg:person.01064603366.33", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01064603366.33"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute for Systems Biology, Seattle, Washington, USA", 
          "id": "http://www.grid.ac/institutes/grid.64212.33", 
          "name": [
            "Institute for Systems Biology, Seattle, Washington, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Donohoe", 
        "givenName": "Sam", 
        "id": "sg:person.013133554347.70", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013133554347.70"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute for Systems Biology, Seattle, Washington, USA", 
          "id": "http://www.grid.ac/institutes/grid.64212.33", 
          "name": [
            "Institute for Systems Biology, Seattle, Washington, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Goodlett", 
        "givenName": "David R.", 
        "id": "sg:person.01044126157.13", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01044126157.13"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute for Systems Biology, Seattle, Washington, USA", 
          "id": "http://www.grid.ac/institutes/grid.64212.33", 
          "name": [
            "Institute for Systems Biology, Seattle, Washington, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Aebersold", 
        "givenName": "Ruedi", 
        "id": "sg:person.015313356237.76", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015313356237.76"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1016/1044-0305(94)80016-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018629105", 
          "https://doi.org/10.1016/1044-0305(94)80016-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/13690", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029022565", 
          "https://doi.org/10.1038/13690"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nbt1001-946", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029399357", 
          "https://doi.org/10.1038/nbt1001-946"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.onc.1202746", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050186337", 
          "https://doi.org/10.1038/sj.onc.1202746"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2003-07-01", 
    "datePublishedReg": "2003-07-01", 
    "description": "A method to identify and quantify chromatin-associated proteins has been developed and applied to the analysis of changes in chromatin-associated proteins induced by Myc oncoprotein expression in human B lymphocytes. Chromatin-enriched fractions were isolated by differential detergent/salt extraction and analyzed by ICAT reagent labeling, multi-dimensional chromatography and tandem mass spectrometry. Many known chromatin-associated regulatory factors were identified and quantified. The method will be widely applicable to various biological systems and reveal changes in chromatin-associated regulatory factors that underlie biological phenomena.", 
    "genre": "article", 
    "id": "sg:pub.10.1016/s1044-0305(03)00204-6", 
    "isAccessibleForFree": true, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.10016041", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1100508", 
        "issn": [
          "1044-0305", 
          "1879-1123"
        ], 
        "name": "Journal of The American Society for Mass Spectrometry", 
        "publisher": "American Chemical Society (ACS)", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "7", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "14"
      }
    ], 
    "keywords": [
      "chromatin-associated proteins", 
      "regulatory factors", 
      "chromatin-enriched fraction", 
      "chromatin-associated factors", 
      "MYC oncoprotein expression", 
      "quantitative proteomic analysis", 
      "proteomic analysis", 
      "biological phenomena", 
      "reagent labeling", 
      "human B lymphocytes", 
      "salt extraction", 
      "protein", 
      "biological systems", 
      "tandem mass spectrometry", 
      "mass spectrometry", 
      "multi-dimensional chromatography", 
      "B lymphocytes", 
      "oncoprotein expression", 
      "expression", 
      "analysis of changes", 
      "labeling", 
      "factors", 
      "changes", 
      "spectrometry", 
      "analysis", 
      "chromatography", 
      "lymphocytes", 
      "fraction", 
      "system", 
      "phenomenon", 
      "method", 
      "extraction"
    ], 
    "name": "Quantitative proteomic analysis of chromatin-associated factors", 
    "pagination": "696-703", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1020708456"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1016/s1044-0305(03)00204-6"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "12837591"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1016/s1044-0305(03)00204-6", 
      "https://app.dimensions.ai/details/publication/pub.1020708456"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-12-01T06:23", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20221201/entities/gbq_results/article/article_368.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1016/s1044-0305(03)00204-6"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1016/s1044-0305(03)00204-6'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1016/s1044-0305(03)00204-6'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1016/s1044-0305(03)00204-6'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1016/s1044-0305(03)00204-6'


 

This table displays all metadata directly associated to this object as RDF triples.

188 TRIPLES      21 PREDICATES      70 URIs      58 LITERALS      16 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1016/s1044-0305(03)00204-6 schema:about N0099b81af73b42069fbabf747b912051
2 N04c4b173e64441fb87201b66e2d63374
3 N20927105c6d34c44b5481e6b5037ab6c
4 N20f1b10d3e074de5a8c9d6f4e981441b
5 N24d644f1f97e452d993089003a2ce893
6 N732a43f1e4e7400887a04775d5dd5fe3
7 Na4337644a89c4d8d8eba94dc6e165e98
8 Nbec380e7b1ef44048cc03653f5e5cd22
9 Nf98c01f6074a4bc19b3bb10d3d859978
10 anzsrc-for:03
11 anzsrc-for:0301
12 schema:author Nb2fcfc76c9b740b08f68509d01a57204
13 schema:citation sg:pub.10.1016/1044-0305(94)80016-2
14 sg:pub.10.1038/13690
15 sg:pub.10.1038/nbt1001-946
16 sg:pub.10.1038/sj.onc.1202746
17 schema:datePublished 2003-07-01
18 schema:datePublishedReg 2003-07-01
19 schema:description A method to identify and quantify chromatin-associated proteins has been developed and applied to the analysis of changes in chromatin-associated proteins induced by Myc oncoprotein expression in human B lymphocytes. Chromatin-enriched fractions were isolated by differential detergent/salt extraction and analyzed by ICAT reagent labeling, multi-dimensional chromatography and tandem mass spectrometry. Many known chromatin-associated regulatory factors were identified and quantified. The method will be widely applicable to various biological systems and reveal changes in chromatin-associated regulatory factors that underlie biological phenomena.
20 schema:genre article
21 schema:isAccessibleForFree true
22 schema:isPartOf N4302eb7e64c746c1a9ab95faf6e34dc0
23 Nefb510894fc747428749cfa5ce82a91a
24 sg:journal.1100508
25 schema:keywords B lymphocytes
26 MYC oncoprotein expression
27 analysis
28 analysis of changes
29 biological phenomena
30 biological systems
31 changes
32 chromatin-associated factors
33 chromatin-associated proteins
34 chromatin-enriched fraction
35 chromatography
36 expression
37 extraction
38 factors
39 fraction
40 human B lymphocytes
41 labeling
42 lymphocytes
43 mass spectrometry
44 method
45 multi-dimensional chromatography
46 oncoprotein expression
47 phenomenon
48 protein
49 proteomic analysis
50 quantitative proteomic analysis
51 reagent labeling
52 regulatory factors
53 salt extraction
54 spectrometry
55 system
56 tandem mass spectrometry
57 schema:name Quantitative proteomic analysis of chromatin-associated factors
58 schema:pagination 696-703
59 schema:productId N168a5210edbe4737b52509ebfbe0b88d
60 N6877148059a8472086b740071cc0cc87
61 Ncb689da5138349719719d52251c4379c
62 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020708456
63 https://doi.org/10.1016/s1044-0305(03)00204-6
64 schema:sdDatePublished 2022-12-01T06:23
65 schema:sdLicense https://scigraph.springernature.com/explorer/license/
66 schema:sdPublisher N45733e8518e244d8997f9f911be45a2c
67 schema:url https://doi.org/10.1016/s1044-0305(03)00204-6
68 sgo:license sg:explorer/license/
69 sgo:sdDataset articles
70 rdf:type schema:ScholarlyArticle
71 N0061b2a6af1d474f85ea6a515dedf37a rdf:first sg:person.015313356237.76
72 rdf:rest rdf:nil
73 N0099b81af73b42069fbabf747b912051 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
74 schema:name Chromosomal Proteins, Non-Histone
75 rdf:type schema:DefinedTerm
76 N04c4b173e64441fb87201b66e2d63374 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
77 schema:name Nuclear Proteins
78 rdf:type schema:DefinedTerm
79 N10f0869defde4a0bba1a5dd514041da1 rdf:first sg:person.01064603366.33
80 rdf:rest N99b11ef33b104ce3a128baae181a4fd9
81 N168a5210edbe4737b52509ebfbe0b88d schema:name dimensions_id
82 schema:value pub.1020708456
83 rdf:type schema:PropertyValue
84 N20927105c6d34c44b5481e6b5037ab6c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
85 schema:name Cell Line
86 rdf:type schema:DefinedTerm
87 N20f1b10d3e074de5a8c9d6f4e981441b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
88 schema:name Humans
89 rdf:type schema:DefinedTerm
90 N24d644f1f97e452d993089003a2ce893 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
91 schema:name Genes, myc
92 rdf:type schema:DefinedTerm
93 N4302eb7e64c746c1a9ab95faf6e34dc0 schema:issueNumber 7
94 rdf:type schema:PublicationIssue
95 N45733e8518e244d8997f9f911be45a2c schema:name Springer Nature - SN SciGraph project
96 rdf:type schema:Organization
97 N53c4bcfe0b6a49229df300e04ff1be79 rdf:first sg:person.01044126157.13
98 rdf:rest N0061b2a6af1d474f85ea6a515dedf37a
99 N6877148059a8472086b740071cc0cc87 schema:name doi
100 schema:value 10.1016/s1044-0305(03)00204-6
101 rdf:type schema:PropertyValue
102 N732a43f1e4e7400887a04775d5dd5fe3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
103 schema:name Up-Regulation
104 rdf:type schema:DefinedTerm
105 N99b11ef33b104ce3a128baae181a4fd9 rdf:first sg:person.013133554347.70
106 rdf:rest N53c4bcfe0b6a49229df300e04ff1be79
107 N9c048929d7b7474c82b190721f755f6c rdf:first sg:person.01256252712.88
108 rdf:rest N10f0869defde4a0bba1a5dd514041da1
109 Na4337644a89c4d8d8eba94dc6e165e98 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
110 schema:name Proteome
111 rdf:type schema:DefinedTerm
112 Nb2fcfc76c9b740b08f68509d01a57204 rdf:first sg:person.0673221741.23
113 rdf:rest N9c048929d7b7474c82b190721f755f6c
114 Nbec380e7b1ef44048cc03653f5e5cd22 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
115 schema:name Chromatin
116 rdf:type schema:DefinedTerm
117 Ncb689da5138349719719d52251c4379c schema:name pubmed_id
118 schema:value 12837591
119 rdf:type schema:PropertyValue
120 Nefb510894fc747428749cfa5ce82a91a schema:volumeNumber 14
121 rdf:type schema:PublicationVolume
122 Nf98c01f6074a4bc19b3bb10d3d859978 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
123 schema:name B-Lymphocytes
124 rdf:type schema:DefinedTerm
125 anzsrc-for:03 schema:inDefinedTermSet anzsrc-for:
126 schema:name Chemical Sciences
127 rdf:type schema:DefinedTerm
128 anzsrc-for:0301 schema:inDefinedTermSet anzsrc-for:
129 schema:name Analytical Chemistry
130 rdf:type schema:DefinedTerm
131 sg:grant.10016041 http://pending.schema.org/fundedItem sg:pub.10.1016/s1044-0305(03)00204-6
132 rdf:type schema:MonetaryGrant
133 sg:journal.1100508 schema:issn 1044-0305
134 1879-1123
135 schema:name Journal of The American Society for Mass Spectrometry
136 schema:publisher American Chemical Society (ACS)
137 rdf:type schema:Periodical
138 sg:person.01044126157.13 schema:affiliation grid-institutes:grid.64212.33
139 schema:familyName Goodlett
140 schema:givenName David R.
141 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01044126157.13
142 rdf:type schema:Person
143 sg:person.01064603366.33 schema:affiliation grid-institutes:grid.64212.33
144 schema:familyName Yi
145 schema:givenName Eugene C.
146 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01064603366.33
147 rdf:type schema:Person
148 sg:person.01256252712.88 schema:affiliation grid-institutes:grid.270240.3
149 schema:familyName Eisenman
150 schema:givenName Robert N.
151 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01256252712.88
152 rdf:type schema:Person
153 sg:person.013133554347.70 schema:affiliation grid-institutes:grid.64212.33
154 schema:familyName Donohoe
155 schema:givenName Sam
156 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013133554347.70
157 rdf:type schema:Person
158 sg:person.015313356237.76 schema:affiliation grid-institutes:grid.64212.33
159 schema:familyName Aebersold
160 schema:givenName Ruedi
161 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015313356237.76
162 rdf:type schema:Person
163 sg:person.0673221741.23 schema:affiliation grid-institutes:grid.64212.33
164 schema:familyName Shiio
165 schema:givenName Yuzuru
166 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0673221741.23
167 rdf:type schema:Person
168 sg:pub.10.1016/1044-0305(94)80016-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018629105
169 https://doi.org/10.1016/1044-0305(94)80016-2
170 rdf:type schema:CreativeWork
171 sg:pub.10.1038/13690 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029022565
172 https://doi.org/10.1038/13690
173 rdf:type schema:CreativeWork
174 sg:pub.10.1038/nbt1001-946 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029399357
175 https://doi.org/10.1038/nbt1001-946
176 rdf:type schema:CreativeWork
177 sg:pub.10.1038/sj.onc.1202746 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050186337
178 https://doi.org/10.1038/sj.onc.1202746
179 rdf:type schema:CreativeWork
180 grid-institutes:grid.270240.3 schema:alternateName Division of Basic Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N. A2-025, 98109-1024, Seattle, WA, USA
181 schema:name Division of Basic Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N. A2-025, 98109-1024, Seattle, WA, USA
182 rdf:type schema:Organization
183 grid-institutes:grid.64212.33 schema:alternateName Institute for Systems Biology, 98103, Seattle, WA
184 Institute for Systems Biology, Seattle, Washington, USA
185 schema:name Division of Basic Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N. A2-025, 98109-1024, Seattle, WA, USA
186 Institute for Systems Biology, 98103, Seattle, WA
187 Institute for Systems Biology, Seattle, Washington, USA
188 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...