Ontology type: schema:ScholarlyArticle Open Access: True
2017-07
AUTHORSAna Claudia Janiszewski Goes, Larissa Aparecida Busatto Reis, Marilia Barreto G. Silva, Barbara Stadler Kahlow, Thelma L. Skare
ABSTRACTResumoAntecedentesOs distúrbios do sono são comuns em pacientes com artrite reumatoide (AR) e contribuem para a perda da qualidade de vida.ObjetivoEstudar as associações entre a qualidade do sono e a dor, depressão e atividade da doença na AR.MétodosEstudo observacional transversal com 112 pacientes com AR submetidos à avaliação do DAS‐28, escala de Epworth para sonolência diurna, qualidade do sono pelo índice de Pittsburg, risco de apneia do sono pelo questionário de Berlim e grau de depressão pelo questionário CES‐D (Center for Epidemiologic Studies Depression). Também foram coletados dados epidemiológicos, clínicos, sorológicos e de tratamento.ResultadosApenas 18,5% dos pacientes com AR tinham uma boa qualidade do sono. Na análise univariada, um sono ruim medido pelo índice de Pittsburg esteve associado à dose diária de prednisona (p=0,03), DAS‐28 (p=0,01), CES‐D (p=0,0005) e mostrou uma tendência a estar associado à apneia do sono pelo questionário de Berlim (p=0,06). Na análise multivariada, somente a depressão (p=0,008) e a apneia do sono pelo questionário de Berlim (p=0,004) mantiveram essa associação.ConclusõesA maior parte dos pacientes com AR não tem uma boa qualidade de sono. A depressão e o risco de apneia do sono estão independentemente associados ao comprometimento do sono.AbstractBackgroundSleep disturbances are common in rheumatoid arthritis (RA) patients and contribute to loss of life quality.ObjectiveTo study associations of sleep quality with pain, depression and disease activity in RA.MethodsThis is a transversal observational study of 112 RA patients submitted to measurement of DAS‐28, Epworth scale for daily sleepiness, index of sleep quality by Pittsburg index, risk of sleep apnea by the Berlin questionnaire and degree of depression by the CES‐D (Center for Epidemiologic Studies Depression scale) questionnaire. We also collected epidemiological, clinical, serological and treatment data.ResultsOnly 18.5% of RA patients had sleep of good quality. In univariate analysis a bad sleep measured by Pittsburg index was associated with daily doses of prednisone (p=0.03), DAS‐28 (p=0.01), CES‐D (p=0.0005) and showed a tendency to be associated with Berlin sleep apnea questionnaire (p=0.06). In multivariate analysis only depression (p=0.008) and Berlin sleep apnea questionnaire (p=0.004) kept this association.ConclusionsMost of RA patients do not have a good sleep quality. Depression and risk of sleep apnea are independently associated with sleep impairment. More... »
PAGES294-298
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DOIhttp://dx.doi.org/10.1016/j.rbr.2016.06.002
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