Ontology type: schema:ScholarlyArticle
2004-08
AUTHORSAkihiko Kobayashi, Toshio Nakagohri, Masaru Konishi, Kazuto Inoue, Shinichirou Takahashi, Masaaki Itou, Masanori Sugitou, Masato Ono, Norio Saito, Taira Kinoshita
ABSTRACTSurgical treatment for locally advanced gastric cancer remains controversial, and many still question the benefits of extended resection. The aim of this study was to evaluate the effectiveness of combined resection of the involved organs with regard to survival in patients with gastric cancer. Between 1993 and 2000, among the 1638 patients with gastric cancer who underwent gastrectomy, 82 were found to have evidence of adjacent organ spread at laparotomy. A retrospective analysis of these patients was performed. Curative resections were carried out in 50 patients, whereas noncurative resections were performed in 32 patients. The 5-year survival rate in the group undergoing curative resection was 36.9%. The survival rate in the R0 group was significantly higher than the survival rate for patients undergoing noncurative resections. There was no significant difference in survival rates between patients with pT3 cancer and those with pT4 cancer. Seventy-one patients were pathologically proved to have lymph node metastasis, and the survival rate for patients with a lymph node ratio greater than 0.2 was lower than that in other groups. In multivariate analysis, peritoneal dissemination, lymph node ratio, and histologic findings were the predictors of survival. Patients with T4 gastric carcinoma, even with lymph node metastasis, might have benefited from aggressive surgery with curative intent. More... »
PAGES464-470
http://scigraph.springernature.com/pub.10.1016/j.gassur.2003.12.018
DOIhttp://dx.doi.org/10.1016/j.gassur.2003.12.018
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PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/15120372
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