Challenging Nanopores with Analyte Scope and Environment View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-03-18

AUTHORS

Buddini I. Karawdeniya, Y. M. Nuwan D. Y. Bandara, Jonathan W. Nichols, Robert B. Chevalier, James T. Hagan, Jason R. Dwyer

ABSTRACT

Nanopores are nanofluidic channels formed through thin membranes that can deliver standout single-molecule and single-particle sensing capabilities. Analytical targets include small molecules and nanoparticles, and the DNA, protein, and glycan biopolymers underpinning genomics, proteomics, and glycomics. Detection—notably even in the simplest implementation, resistive-pulse sensing—does not inherently require sample labeling and, thus, offers the potential for general sensing utility combined with the prospective benefits of reduced sample processing requirements. A key pursuit for biopolymer sensing is the characterization of monomer sequence. This review article will provide an overview of the use of nanopores for general chemical sensing and –omics-related applications, writ-large. The broad analyte scope provides fertile ground for a discussion of principles governing nanopore sensing and considerations useful for guiding nanopore development. For nanopores to be effective in the face of broad analyte scope, stringent requirements on analytical performance must be met within the particular analyte class without sacrificing the operational flexibility necessary to be responsive across classes presenting very different physical and chemical challenges. These sample-driven challenges provide a unifying framework for discussing aspects of nanopore fabrication, properties, and integration; sensing paradigms, performance, and prospects; fundamental electrokinetic and interfacial phenomena; and practical challenges facing the use and further development of nanopore devices. More... »

PAGES

1-19

References to SciGraph publications

  • 2018-12. Label-free analysis of physiological hyaluronan size distribution with a solid-state nanopore sensor in NATURE COMMUNICATIONS
  • 2009-06. Chemical glycobiology: why now? in NATURE CHEMICAL BIOLOGY
  • 2018-12. Surveying silicon nitride nanopores for glycomics and heparin quality assurance in NATURE COMMUNICATIONS
  • 2017-12. Nanopore DNA Sequencing and Genome Assembly on the International Space Station in SCIENTIFIC REPORTS
  • 2001-10. The bittersweet promise of glycobiology in NATURE BIOTECHNOLOGY
  • 2016-02. Decoding DNA, RNA and peptides with quantum tunnelling in NATURE NANOTECHNOLOGY
  • 2010-02. Glycosylation of Therapeutic Proteins in BIODRUGS
  • 2004-03. Tropical infectious diseases: Diagnostics for the developing world in NATURE REVIEWS MICROBIOLOGY
  • 2008-10. The potential and challenges of nanopore sequencing in NATURE BIOTECHNOLOGY
  • 2002-01. Aptasensors – the future of biosensing? in ANALYTICAL AND BIOANALYTICAL CHEMISTRY
  • 2010-02. Electrostatic focusing of unlabelled DNA into nanoscale pores using a salt gradient in NATURE NANOTECHNOLOGY
  • 2016-02. Real-time, portable genome sequencing for Ebola surveillance in NATURE
  • 2018-09. Paving the way to single-molecule protein sequencing in NATURE NANOTECHNOLOGY
  • 2007-11. The α-Hemolysin nanopore transduction detector – single-molecule binding studies and immunological screening of antibodies and aptamers in BMC BIOINFORMATICS
  • 2000-09. Simultaneous stochastic sensing of divalent metal ions in NATURE BIOTECHNOLOGY
  • 2017-05. Real-time shape approximation and fingerprinting of single proteins using a nanopore in NATURE NANOTECHNOLOGY
  • 2003-08. Fabrication of solid-state nanopores with single-nanometre precision in NATURE MATERIALS
  • 2008-06. Oversulfated chondroitin sulfate is a contaminant in heparin associated with adverse clinical events in NATURE BIOTECHNOLOGY
  • 2011-04. Controlling protein translocation through nanopores with bio-inspired fluid walls in NATURE NANOTECHNOLOGY
  • 2003-09. DNA molecules and configurations in a solid-state nanopore microscope in NATURE MATERIALS
  • 2006-08. Aptamers come of age – at last in NATURE REVIEWS MICROBIOLOGY
  • 2007-08. Synthetic pores with reactive signal amplifiers as artificial tongues in NATURE MATERIALS
  • 2018-12. A handheld platform for target protein detection and quantification using disposable nanopore strips in SCIENTIFIC REPORTS
  • 2009-08. From carbohydrate leads to glycomimetic drugs in NATURE REVIEWS DRUG DISCOVERY
  • 2013-12. Single molecule unfolding and stretching of protein domains inside a solid-state nanopore by electric field in SCIENTIFIC REPORTS
  • 2001-07. Ion-beam sculpting at nanometre length scales in NATURE
  • 2007-04. Single-molecule analysis of DNA-protein complexes using nanopores in NATURE METHODS
  • 2009-01. Advances in the separation, sensitive detection, and characterization of heparin and heparan sulfate in ANALYTICAL AND BIOANALYTICAL CHEMISTRY
  • 2015-09. Glycosylation in cancer: mechanisms and clinical implications in NATURE REVIEWS CANCER
  • 1992-02. Selection of single-stranded DNA molecules that bind and inhibit human thrombin in NATURE
  • 2017-03-22. Biochemistry: A wine-induced breakdown in NATURE
  • 2013-08. Glycobiology of cell death: when glycans and lectins govern cell fate in CELL DEATH & DIFFERENTIATION
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s41664-019-00092-1

    DOI

    http://dx.doi.org/10.1007/s41664-019-00092-1

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1112854302


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0303", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Macromolecular and Materials Chemistry", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/03", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Chemical Sciences", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "Southern Methodist University", 
              "id": "https://www.grid.ac/institutes/grid.263864.d", 
              "name": [
                "Department of Mechanical Engineering, Lyle School of Engineering, Southern Methodist University, 75275, Dallas, TX, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Karawdeniya", 
            "givenName": "Buddini I.", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Southern Methodist University", 
              "id": "https://www.grid.ac/institutes/grid.263864.d", 
              "name": [
                "Department of Mechanical Engineering, Lyle School of Engineering, Southern Methodist University, 75275, Dallas, TX, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Bandara", 
            "givenName": "Y. M. Nuwan D. Y.", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "Nova Biomedical, 200 Prospect Street, 02454-9141, Waltham, MA, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Nichols", 
            "givenName": "Jonathan W.", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Rhode Island", 
              "id": "https://www.grid.ac/institutes/grid.20431.34", 
              "name": [
                "Department of Chemistry, University of Rhode Island, Richard E. Beaupre Center for Chemical and Forensic Sciences, 140 Flagg Rd., 02881, Kingston, RI, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Chevalier", 
            "givenName": "Robert B.", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Rhode Island", 
              "id": "https://www.grid.ac/institutes/grid.20431.34", 
              "name": [
                "Department of Chemistry, University of Rhode Island, Richard E. Beaupre Center for Chemical and Forensic Sciences, 140 Flagg Rd., 02881, Kingston, RI, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Hagan", 
            "givenName": "James T.", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Rhode Island", 
              "id": "https://www.grid.ac/institutes/grid.20431.34", 
              "name": [
                "Department of Chemistry, University of Rhode Island, Richard E. Beaupre Center for Chemical and Forensic Sciences, 140 Flagg Rd., 02881, Kingston, RI, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Dwyer", 
            "givenName": "Jason R.", 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "sg:pub.10.1038/355564a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000063370", 
              "https://doi.org/10.1038/355564a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nnano.2009.379", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000093273", 
              "https://doi.org/10.1038/nnano.2009.379"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nnano.2009.379", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000093273", 
              "https://doi.org/10.1038/nnano.2009.379"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/smll.200901435", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000351901"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/smll.200901435", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000351901"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrmicro1458", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000514347", 
              "https://doi.org/10.1038/nrmicro1458"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrmicro1458", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000514347", 
              "https://doi.org/10.1038/nrmicro1458"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00216-001-1189-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000886980", 
              "https://doi.org/10.1007/s00216-001-1189-3"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2217/17435889.2.6.875", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001374857"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/glycob/cwn026", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001710377"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1039/c3lc50069a", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001986324"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/smll.201303602", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002744639"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2217/17435889.2.4.459", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003026977"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrd2852", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003755355", 
              "https://doi.org/10.1038/nrd2852"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrd2852", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003755355", 
              "https://doi.org/10.1038/nrd2852"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1056/nejmoa0803200", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004063974"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1039/b813796j", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005776619"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1039/b813796j", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005776619"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/nl100861c", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006025111"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/nl100861c", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006025111"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0301-4622(99)00108-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006655249"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/acs.analchem.5b01167", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006902654"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/ja0739943", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007341840"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/ja0739943", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007341840"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/nn506572r", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007502029"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1529/biophysj.108.137760", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007694232"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/srep01638", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007697893", 
              "https://doi.org/10.1038/srep01638"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1039/c2cs35286a", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008476698"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/nl802218f", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008946858"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/nl802218f", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008946858"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pone.0054982", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010514425"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/ac200195n", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011570766"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/ac200195n", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011570766"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1088/0957-4484/23/43/435301", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012182887"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/nl052107w", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012253571"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/nl052107w", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012253571"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.copbio.2010.05.002", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013285653"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/nl070462b", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013352629"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/nl070462b", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013352629"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1063/1.4794973", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013728574"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.1001831107", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014637542"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nmeth1021", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014966509", 
              "https://doi.org/10.1038/nmeth1021"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1529/biophysj.105.079111", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015056699"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1039/b504827c", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016163254"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1039/b504827c", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016163254"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.93.24.13770", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016336761"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/acs.analchem.6b04260", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018324181"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1529/biophysj.104.057406", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018863347"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.0911450106", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019576041"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1006/jmbi.1997.1275", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020188010"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/elps.201500561", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020999179"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1039/c1nr00003a", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021748414"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/anie.201205687", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022008360"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1529/biophysj.104.047274", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022535175"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/ac502596m", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022753337"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0165-9936(03)01208-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023219987"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/nl404183t", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023961623"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrmicro841", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024064458", 
              "https://doi.org/10.1038/nrmicro841"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrmicro841", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024064458", 
              "https://doi.org/10.1038/nrmicro841"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1039/b819896a", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024172237"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/ja043910f", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024547443"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/ja043910f", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024547443"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1088/0960-1317/25/1/015011", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025224032"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/ac2010857", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025516081"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/ac2010857", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025516081"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.2165/11530550-000000000-00000", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025543499", 
              "https://doi.org/10.2165/11530550-000000000-00000"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.2165/11530550-000000000-00000", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025543499", 
              "https://doi.org/10.2165/11530550-000000000-00000"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/nn405045x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025900472"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/cr980099g", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1026153115"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/cr980099g", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1026153115"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1039/c0cs00053a", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1026644173"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1039/b9nr00275h", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027381592"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1039/b9nr00275h", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027381592"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pone.0092880", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027623543"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1039/b708725j", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027637706"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/79275", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027719967", 
              "https://doi.org/10.1038/79275"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/79275", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027719967", 
              "https://doi.org/10.1038/79275"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/acssensors.6b00564", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027952981"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1088/0957-4484/21/14/145102", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028137039"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1088/0957-4484/21/14/145102", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028137039"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1039/c2cc17277a", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028397297"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/ac9006705", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028681973"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/ac9006705", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028681973"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/ja063485l", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028824814"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/ja063485l", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028824814"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1088/0957-4484/22/31/315101", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028867644"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1039/c4an01439a", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028909240"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1471-2105-8-s7-s9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029298906", 
              "https://doi.org/10.1186/1471-2105-8-s7-s9"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/nl050925i", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029757745"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/nl050925i", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029757745"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/nl301412b", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030008858"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.1225624", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030772710"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nmat941", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030841250", 
              "https://doi.org/10.1038/nmat941"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nmat941", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030841250", 
              "https://doi.org/10.1038/nmat941"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nnano.2016.267", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031235323", 
              "https://doi.org/10.1038/nnano.2016.267"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/ac300129e", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031308457"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1039/b900409m", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031648657"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1063/1.4948525", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032011820"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/ar900165x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032386937"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/ar900165x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032386937"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/elps.201400612", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032481811"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00216-008-2412-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034004162", 
              "https://doi.org/10.1007/s00216-008-2412-2"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00216-008-2412-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034004162", 
              "https://doi.org/10.1007/s00216-008-2412-2"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.1235681", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034393517"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.1235681", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034393517"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.electacta.2010.03.051", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034586559"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt1407", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034846157", 
              "https://doi.org/10.1038/nbt1407"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1039/c6lc01173j", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034969996"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1039/c6nr07339e", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035609121"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.nantod.2012.12.008", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035860670"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1063/1.4921620", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036116999"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/smll.200700106", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036184351"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/am800121d", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036339080"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/cbic.200500064", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036358057"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrc3982", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036508003", 
              "https://doi.org/10.1038/nrc3982"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/ac504186m", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037026856"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt.1495", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037155475", 
              "https://doi.org/10.1038/nbt.1495"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1039/c5an00075k", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037223398"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nnano.2011.12", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037237720", 
              "https://doi.org/10.1038/nnano.2011.12"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1039/b607360c", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037488044"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1039/c0cc02649b", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037502556"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1039/c0cc02649b", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037502556"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/smll.201001428", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038308773"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/smll.201001428", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038308773"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/cr300381m", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038313680"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1529/biophysj.106.094060", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038919191"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1529/biophysj.108.140475", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039688081"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/nn3051677", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039769464"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/ac504180h", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039901320"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nchembio0609-368", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040044976", 
              "https://doi.org/10.1038/nchembio0609-368"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nchembio0609-368", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040044976", 
              "https://doi.org/10.1038/nchembio0609-368"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1088/0957-4484/18/30/305505", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040789246"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1103/physrevlett.93.035901", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040946543"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1103/physrevlett.93.035901", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040946543"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bios.2012.05.013", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041710109"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/cbic.200900526", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042880151"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/cbic.200900526", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042880151"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nmat965", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043496789", 
              "https://doi.org/10.1038/nmat965"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nmat965", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043496789", 
              "https://doi.org/10.1038/nmat965"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/nn900713a", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043712272"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.elecom.2013.09.009", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043783467"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nmat1933", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043783923", 
              "https://doi.org/10.1038/nmat1933"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.1151298", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044477038"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1088/0953-8984/22/45/454133", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044582000"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1088/0953-8984/22/45/454133", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044582000"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/35084037", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045265151", 
              "https://doi.org/10.1038/35084037"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/35084037", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045265151", 
              "https://doi.org/10.1038/35084037"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/am4026455", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045953260"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/cdd.2013.50", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046171448", 
              "https://doi.org/10.1038/cdd.2013.50"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/smll.201000253", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046517910"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/smll.201000253", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046517910"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1088/0957-4484/23/40/405301", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047112434"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature16996", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047444576", 
              "https://doi.org/10.1038/nature16996"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/nn5042398", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047632012"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.snb.2011.12.070", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048001547"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nnano.2015.320", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048522255", 
              "https://doi.org/10.1038/nnano.2015.320"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1529/biophysj.104.040212", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048744447"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1063/1.1404988", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049354159"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1088/0953-8984/22/45/450301", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049534002"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bbrc.2011.07.121", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050069398"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1088/0953-8984/22/45/454104", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050470100"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1088/0953-8984/22/45/454104", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050470100"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.plrev.2012.05.010", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050778379"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.plrev.2012.05.010", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050778379"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt1001-913", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051860859", 
              "https://doi.org/10.1038/nbt1001-913"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt1001-913", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051860859", 
              "https://doi.org/10.1038/nbt1001-913"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1039/c3nr02105j", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052108454"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.1002194107", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052252626"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/ja2026085", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052501552"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/ja2026085", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052501552"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1529/biophysj.106.102855", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053058515"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/ja4053398", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053288285"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0006-3495(02)75442-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053541079"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/cr990343j", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053968440"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/cr990343j", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053968440"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/ac00109a003", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1054972453"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/ac101269u", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1055000520"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/ac101269u", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1055000520"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/ac4020929", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1055004703"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/ac403969n", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1055005269"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/ac501089m", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1055016073"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/acs.analchem.5b02611", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1055078882"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/acs.analchem.5b03347", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1055079095"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/acsami.6b10045", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1055131849"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/acsami.6b12720", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1055132514"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/am501971n", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1055145644"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/ar700229r", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1055151723"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/ar700229r", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1055151723"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/cb2004737", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1055226111"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/cb300449t", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1055226272"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/jm030176m", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1055947958"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/jm030176m", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1055947958"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/jp0775911", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1056074963"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/jp0775911", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1056074963"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/jp305381j", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1056090106"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/la400716c", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1056157817"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/nn301125y", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1056224322"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/nn301672g", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1056224409"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/nn3031047", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1056224648"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/nn303900y", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1056224759"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/nn401759r", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1056225253"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1063/1.1684724", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1057760416"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1063/1.3521411", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1057967116"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1103/physrevlett.102.256804", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1060755594"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1103/physrevlett.102.256804", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1060755594"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1103/physrevlett.109.024501", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1060760047"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1103/physrevlett.109.024501", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1060760047"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1103/revmodphys.80.839", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1060839667"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1103/revmodphys.80.839", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1060839667"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1109/84.546406", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1061240560"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.274.5294.1859", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1062555213"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.291.5512.2364", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1062573344"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.291.5512.2370", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1062573345"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1209/0295-5075/82/48003", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064232057"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1074515144", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/153537020623100211", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1077181934"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/153537020623100211", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1077181934"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature21901", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1084128623", 
              "https://doi.org/10.1038/nature21901"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/0003702817715496", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1086055048"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/0003702817715496", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1086055048"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.cis.2017.09.001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1091733766"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/elps.201700299", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1092655183"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/s41598-017-18364-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1099733334", 
              "https://doi.org/10.1038/s41598-017-18364-0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/acscentsci.7b00576", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1100422592"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/acsanm.7b00385", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1100522882"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/s41467-018-03439-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1101436482", 
              "https://doi.org/10.1038/s41467-018-03439-x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/s41467-018-03439-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1101436482", 
              "https://doi.org/10.1038/s41467-018-03439-x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/s41467-018-03439-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1101436482", 
              "https://doi.org/10.1038/s41467-018-03439-x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/s41467-018-05751-y", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1106100326", 
              "https://doi.org/10.1038/s41467-018-05751-y"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/s41565-018-0236-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1106432298", 
              "https://doi.org/10.1038/s41565-018-0236-6"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/adma.201704680", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1106897463"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/s41598-018-33086-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1107306582", 
              "https://doi.org/10.1038/s41598-018-33086-7"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/acs.analchem.8b04136", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1109812859"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/adfm.201807555", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1110223990"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2019-03-18", 
        "datePublishedReg": "2019-03-18", 
        "description": "Nanopores are nanofluidic channels formed through thin membranes that can deliver standout single-molecule and single-particle sensing capabilities. Analytical targets include small molecules and nanoparticles, and the DNA, protein, and glycan biopolymers underpinning genomics, proteomics, and glycomics. Detection\u2014notably even in the simplest implementation, resistive-pulse sensing\u2014does not inherently require sample labeling and, thus, offers the potential for general sensing utility combined with the prospective benefits of reduced sample processing requirements. A key pursuit for biopolymer sensing is the characterization of monomer sequence. This review article will provide an overview of the use of nanopores for general chemical sensing and \u2013omics-related applications, writ-large. The broad analyte scope provides fertile ground for a discussion of principles governing nanopore sensing and considerations useful for guiding nanopore development. For nanopores to be effective in the face of broad analyte scope, stringent requirements on analytical performance must be met within the particular analyte class without sacrificing the operational flexibility necessary to be responsive across classes presenting very different physical and chemical challenges. These sample-driven challenges provide a unifying framework for discussing aspects of nanopore fabrication, properties, and integration; sensing paradigms, performance, and prospects; fundamental electrokinetic and interfacial phenomena; and practical challenges facing the use and further development of nanopore devices.", 
        "genre": "research_article", 
        "id": "sg:pub.10.1007/s41664-019-00092-1", 
        "inLanguage": [
          "en"
        ], 
        "isAccessibleForFree": false, 
        "isFundedItemOf": [
          {
            "id": "sg:grant.7703871", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.3133026", 
            "type": "MonetaryGrant"
          }
        ], 
        "isPartOf": [
          {
            "id": "sg:journal.1290430", 
            "issn": [
              "2096-241X", 
              "2509-4696"
            ], 
            "name": "Journal of Analysis and Testing", 
            "type": "Periodical"
          }
        ], 
        "name": "Challenging Nanopores with Analyte Scope and Environment", 
        "pagination": "1-19", 
        "productId": [
          {
            "name": "readcube_id", 
            "type": "PropertyValue", 
            "value": [
              "7efcb6c839afb33725f40bbcd0706849e2fb80d807ed739fe6f1b94a115e6f83"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1007/s41664-019-00092-1"
            ]
          }, 
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1112854302"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1007/s41664-019-00092-1", 
          "https://app.dimensions.ai/details/publication/pub.1112854302"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2019-04-11T12:15", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000361_0000000361/records_54014_00000002.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "https://link.springer.com/10.1007%2Fs41664-019-00092-1"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s41664-019-00092-1'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s41664-019-00092-1'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s41664-019-00092-1'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s41664-019-00092-1'


     

    This table displays all metadata directly associated to this object as RDF triples.

    670 TRIPLES      21 PREDICATES      206 URIs      16 LITERALS      5 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1007/s41664-019-00092-1 schema:about anzsrc-for:03
    2 anzsrc-for:0303
    3 schema:author N3e844ec34891478aa5567c39392242a3
    4 schema:citation sg:pub.10.1007/s00216-001-1189-3
    5 sg:pub.10.1007/s00216-008-2412-2
    6 sg:pub.10.1038/35084037
    7 sg:pub.10.1038/355564a0
    8 sg:pub.10.1038/79275
    9 sg:pub.10.1038/cdd.2013.50
    10 sg:pub.10.1038/nature16996
    11 sg:pub.10.1038/nature21901
    12 sg:pub.10.1038/nbt.1495
    13 sg:pub.10.1038/nbt1001-913
    14 sg:pub.10.1038/nbt1407
    15 sg:pub.10.1038/nchembio0609-368
    16 sg:pub.10.1038/nmat1933
    17 sg:pub.10.1038/nmat941
    18 sg:pub.10.1038/nmat965
    19 sg:pub.10.1038/nmeth1021
    20 sg:pub.10.1038/nnano.2009.379
    21 sg:pub.10.1038/nnano.2011.12
    22 sg:pub.10.1038/nnano.2015.320
    23 sg:pub.10.1038/nnano.2016.267
    24 sg:pub.10.1038/nrc3982
    25 sg:pub.10.1038/nrd2852
    26 sg:pub.10.1038/nrmicro1458
    27 sg:pub.10.1038/nrmicro841
    28 sg:pub.10.1038/s41467-018-03439-x
    29 sg:pub.10.1038/s41467-018-05751-y
    30 sg:pub.10.1038/s41565-018-0236-6
    31 sg:pub.10.1038/s41598-017-18364-0
    32 sg:pub.10.1038/s41598-018-33086-7
    33 sg:pub.10.1038/srep01638
    34 sg:pub.10.1186/1471-2105-8-s7-s9
    35 sg:pub.10.2165/11530550-000000000-00000
    36 https://app.dimensions.ai/details/publication/pub.1074515144
    37 https://doi.org/10.1002/adfm.201807555
    38 https://doi.org/10.1002/adma.201704680
    39 https://doi.org/10.1002/anie.201205687
    40 https://doi.org/10.1002/cbic.200500064
    41 https://doi.org/10.1002/cbic.200900526
    42 https://doi.org/10.1002/elps.201400612
    43 https://doi.org/10.1002/elps.201500561
    44 https://doi.org/10.1002/elps.201700299
    45 https://doi.org/10.1002/smll.200700106
    46 https://doi.org/10.1002/smll.200901435
    47 https://doi.org/10.1002/smll.201000253
    48 https://doi.org/10.1002/smll.201001428
    49 https://doi.org/10.1002/smll.201303602
    50 https://doi.org/10.1006/jmbi.1997.1275
    51 https://doi.org/10.1016/j.bbrc.2011.07.121
    52 https://doi.org/10.1016/j.bios.2012.05.013
    53 https://doi.org/10.1016/j.cis.2017.09.001
    54 https://doi.org/10.1016/j.copbio.2010.05.002
    55 https://doi.org/10.1016/j.elecom.2013.09.009
    56 https://doi.org/10.1016/j.electacta.2010.03.051
    57 https://doi.org/10.1016/j.nantod.2012.12.008
    58 https://doi.org/10.1016/j.plrev.2012.05.010
    59 https://doi.org/10.1016/j.snb.2011.12.070
    60 https://doi.org/10.1016/s0006-3495(02)75442-8
    61 https://doi.org/10.1016/s0165-9936(03)01208-1
    62 https://doi.org/10.1016/s0301-4622(99)00108-8
    63 https://doi.org/10.1021/ac00109a003
    64 https://doi.org/10.1021/ac101269u
    65 https://doi.org/10.1021/ac200195n
    66 https://doi.org/10.1021/ac2010857
    67 https://doi.org/10.1021/ac300129e
    68 https://doi.org/10.1021/ac4020929
    69 https://doi.org/10.1021/ac403969n
    70 https://doi.org/10.1021/ac501089m
    71 https://doi.org/10.1021/ac502596m
    72 https://doi.org/10.1021/ac504180h
    73 https://doi.org/10.1021/ac504186m
    74 https://doi.org/10.1021/ac9006705
    75 https://doi.org/10.1021/acs.analchem.5b01167
    76 https://doi.org/10.1021/acs.analchem.5b02611
    77 https://doi.org/10.1021/acs.analchem.5b03347
    78 https://doi.org/10.1021/acs.analchem.6b04260
    79 https://doi.org/10.1021/acs.analchem.8b04136
    80 https://doi.org/10.1021/acsami.6b10045
    81 https://doi.org/10.1021/acsami.6b12720
    82 https://doi.org/10.1021/acsanm.7b00385
    83 https://doi.org/10.1021/acscentsci.7b00576
    84 https://doi.org/10.1021/acssensors.6b00564
    85 https://doi.org/10.1021/am4026455
    86 https://doi.org/10.1021/am501971n
    87 https://doi.org/10.1021/am800121d
    88 https://doi.org/10.1021/ar700229r
    89 https://doi.org/10.1021/ar900165x
    90 https://doi.org/10.1021/cb2004737
    91 https://doi.org/10.1021/cb300449t
    92 https://doi.org/10.1021/cr300381m
    93 https://doi.org/10.1021/cr980099g
    94 https://doi.org/10.1021/cr990343j
    95 https://doi.org/10.1021/ja043910f
    96 https://doi.org/10.1021/ja063485l
    97 https://doi.org/10.1021/ja0739943
    98 https://doi.org/10.1021/ja2026085
    99 https://doi.org/10.1021/ja4053398
    100 https://doi.org/10.1021/jm030176m
    101 https://doi.org/10.1021/jp0775911
    102 https://doi.org/10.1021/jp305381j
    103 https://doi.org/10.1021/la400716c
    104 https://doi.org/10.1021/nl050925i
    105 https://doi.org/10.1021/nl052107w
    106 https://doi.org/10.1021/nl070462b
    107 https://doi.org/10.1021/nl100861c
    108 https://doi.org/10.1021/nl301412b
    109 https://doi.org/10.1021/nl404183t
    110 https://doi.org/10.1021/nl802218f
    111 https://doi.org/10.1021/nn301125y
    112 https://doi.org/10.1021/nn301672g
    113 https://doi.org/10.1021/nn3031047
    114 https://doi.org/10.1021/nn303900y
    115 https://doi.org/10.1021/nn3051677
    116 https://doi.org/10.1021/nn401759r
    117 https://doi.org/10.1021/nn405045x
    118 https://doi.org/10.1021/nn5042398
    119 https://doi.org/10.1021/nn506572r
    120 https://doi.org/10.1021/nn900713a
    121 https://doi.org/10.1039/b504827c
    122 https://doi.org/10.1039/b607360c
    123 https://doi.org/10.1039/b708725j
    124 https://doi.org/10.1039/b813796j
    125 https://doi.org/10.1039/b819896a
    126 https://doi.org/10.1039/b900409m
    127 https://doi.org/10.1039/b9nr00275h
    128 https://doi.org/10.1039/c0cc02649b
    129 https://doi.org/10.1039/c0cs00053a
    130 https://doi.org/10.1039/c1nr00003a
    131 https://doi.org/10.1039/c2cc17277a
    132 https://doi.org/10.1039/c2cs35286a
    133 https://doi.org/10.1039/c3lc50069a
    134 https://doi.org/10.1039/c3nr02105j
    135 https://doi.org/10.1039/c4an01439a
    136 https://doi.org/10.1039/c5an00075k
    137 https://doi.org/10.1039/c6lc01173j
    138 https://doi.org/10.1039/c6nr07339e
    139 https://doi.org/10.1056/nejmoa0803200
    140 https://doi.org/10.1063/1.1404988
    141 https://doi.org/10.1063/1.1684724
    142 https://doi.org/10.1063/1.3521411
    143 https://doi.org/10.1063/1.4794973
    144 https://doi.org/10.1063/1.4921620
    145 https://doi.org/10.1063/1.4948525
    146 https://doi.org/10.1073/pnas.0911450106
    147 https://doi.org/10.1073/pnas.1001831107
    148 https://doi.org/10.1073/pnas.1002194107
    149 https://doi.org/10.1073/pnas.93.24.13770
    150 https://doi.org/10.1088/0953-8984/22/45/450301
    151 https://doi.org/10.1088/0953-8984/22/45/454104
    152 https://doi.org/10.1088/0953-8984/22/45/454133
    153 https://doi.org/10.1088/0957-4484/18/30/305505
    154 https://doi.org/10.1088/0957-4484/21/14/145102
    155 https://doi.org/10.1088/0957-4484/22/31/315101
    156 https://doi.org/10.1088/0957-4484/23/40/405301
    157 https://doi.org/10.1088/0957-4484/23/43/435301
    158 https://doi.org/10.1088/0960-1317/25/1/015011
    159 https://doi.org/10.1093/glycob/cwn026
    160 https://doi.org/10.1103/physrevlett.102.256804
    161 https://doi.org/10.1103/physrevlett.109.024501
    162 https://doi.org/10.1103/physrevlett.93.035901
    163 https://doi.org/10.1103/revmodphys.80.839
    164 https://doi.org/10.1109/84.546406
    165 https://doi.org/10.1126/science.1151298
    166 https://doi.org/10.1126/science.1225624
    167 https://doi.org/10.1126/science.1235681
    168 https://doi.org/10.1126/science.274.5294.1859
    169 https://doi.org/10.1126/science.291.5512.2364
    170 https://doi.org/10.1126/science.291.5512.2370
    171 https://doi.org/10.1177/0003702817715496
    172 https://doi.org/10.1177/153537020623100211
    173 https://doi.org/10.1209/0295-5075/82/48003
    174 https://doi.org/10.1371/journal.pone.0054982
    175 https://doi.org/10.1371/journal.pone.0092880
    176 https://doi.org/10.1529/biophysj.104.040212
    177 https://doi.org/10.1529/biophysj.104.047274
    178 https://doi.org/10.1529/biophysj.104.057406
    179 https://doi.org/10.1529/biophysj.105.079111
    180 https://doi.org/10.1529/biophysj.106.094060
    181 https://doi.org/10.1529/biophysj.106.102855
    182 https://doi.org/10.1529/biophysj.108.137760
    183 https://doi.org/10.1529/biophysj.108.140475
    184 https://doi.org/10.2217/17435889.2.4.459
    185 https://doi.org/10.2217/17435889.2.6.875
    186 schema:datePublished 2019-03-18
    187 schema:datePublishedReg 2019-03-18
    188 schema:description Nanopores are nanofluidic channels formed through thin membranes that can deliver standout single-molecule and single-particle sensing capabilities. Analytical targets include small molecules and nanoparticles, and the DNA, protein, and glycan biopolymers underpinning genomics, proteomics, and glycomics. Detection—notably even in the simplest implementation, resistive-pulse sensing—does not inherently require sample labeling and, thus, offers the potential for general sensing utility combined with the prospective benefits of reduced sample processing requirements. A key pursuit for biopolymer sensing is the characterization of monomer sequence. This review article will provide an overview of the use of nanopores for general chemical sensing and –omics-related applications, writ-large. The broad analyte scope provides fertile ground for a discussion of principles governing nanopore sensing and considerations useful for guiding nanopore development. For nanopores to be effective in the face of broad analyte scope, stringent requirements on analytical performance must be met within the particular analyte class without sacrificing the operational flexibility necessary to be responsive across classes presenting very different physical and chemical challenges. These sample-driven challenges provide a unifying framework for discussing aspects of nanopore fabrication, properties, and integration; sensing paradigms, performance, and prospects; fundamental electrokinetic and interfacial phenomena; and practical challenges facing the use and further development of nanopore devices.
    189 schema:genre research_article
    190 schema:inLanguage en
    191 schema:isAccessibleForFree false
    192 schema:isPartOf sg:journal.1290430
    193 schema:name Challenging Nanopores with Analyte Scope and Environment
    194 schema:pagination 1-19
    195 schema:productId N62c9dd714adf4d089a9c9842b596b949
    196 N97d4f046fc9542fc96f550e754a9f244
    197 Naf413a43416e4edf9f386adb7659e546
    198 schema:sameAs https://app.dimensions.ai/details/publication/pub.1112854302
    199 https://doi.org/10.1007/s41664-019-00092-1
    200 schema:sdDatePublished 2019-04-11T12:15
    201 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    202 schema:sdPublisher Nae630faa629241e5bebbeaa2109a1ff2
    203 schema:url https://link.springer.com/10.1007%2Fs41664-019-00092-1
    204 sgo:license sg:explorer/license/
    205 sgo:sdDataset articles
    206 rdf:type schema:ScholarlyArticle
    207 N003a5024679744e9a6a8edd18d31c369 rdf:first N54b89b36c9424d84a4168ac409b0e755
    208 rdf:rest rdf:nil
    209 N10b73d588e9d41bfb87b4e37dbd81928 rdf:first Nbfb8fb214c57414bbf8b755fab169f17
    210 rdf:rest N15e5b71671d84fdca9a97d1bc0a37ea3
    211 N15e5b71671d84fdca9a97d1bc0a37ea3 rdf:first Ncb68fa7d47b8446fa57b96c34ef33c4d
    212 rdf:rest N37a6a8a06a6b46c29d95b3123baf3ed7
    213 N37a6a8a06a6b46c29d95b3123baf3ed7 rdf:first Nf4d5d5eb0f864ac4a1fdf26d9525d1d1
    214 rdf:rest N43a5ec53f35d4e0b8d5edec2a83e3b34
    215 N3e844ec34891478aa5567c39392242a3 rdf:first N462d8f95b839452ab6b0e579a525d486
    216 rdf:rest N10b73d588e9d41bfb87b4e37dbd81928
    217 N43a5ec53f35d4e0b8d5edec2a83e3b34 rdf:first N74f1d15ad09f42cd8c7163f39922230b
    218 rdf:rest N003a5024679744e9a6a8edd18d31c369
    219 N462d8f95b839452ab6b0e579a525d486 schema:affiliation https://www.grid.ac/institutes/grid.263864.d
    220 schema:familyName Karawdeniya
    221 schema:givenName Buddini I.
    222 rdf:type schema:Person
    223 N54b89b36c9424d84a4168ac409b0e755 schema:affiliation https://www.grid.ac/institutes/grid.20431.34
    224 schema:familyName Dwyer
    225 schema:givenName Jason R.
    226 rdf:type schema:Person
    227 N62c9dd714adf4d089a9c9842b596b949 schema:name doi
    228 schema:value 10.1007/s41664-019-00092-1
    229 rdf:type schema:PropertyValue
    230 N74f1d15ad09f42cd8c7163f39922230b schema:affiliation https://www.grid.ac/institutes/grid.20431.34
    231 schema:familyName Hagan
    232 schema:givenName James T.
    233 rdf:type schema:Person
    234 N97d4f046fc9542fc96f550e754a9f244 schema:name dimensions_id
    235 schema:value pub.1112854302
    236 rdf:type schema:PropertyValue
    237 Nae630faa629241e5bebbeaa2109a1ff2 schema:name Springer Nature - SN SciGraph project
    238 rdf:type schema:Organization
    239 Naf413a43416e4edf9f386adb7659e546 schema:name readcube_id
    240 schema:value 7efcb6c839afb33725f40bbcd0706849e2fb80d807ed739fe6f1b94a115e6f83
    241 rdf:type schema:PropertyValue
    242 Nbfb8fb214c57414bbf8b755fab169f17 schema:affiliation https://www.grid.ac/institutes/grid.263864.d
    243 schema:familyName Bandara
    244 schema:givenName Y. M. Nuwan D. Y.
    245 rdf:type schema:Person
    246 Ncb68fa7d47b8446fa57b96c34ef33c4d schema:affiliation Nfd7a0b622cdf43c09278c8fecd023871
    247 schema:familyName Nichols
    248 schema:givenName Jonathan W.
    249 rdf:type schema:Person
    250 Nf4d5d5eb0f864ac4a1fdf26d9525d1d1 schema:affiliation https://www.grid.ac/institutes/grid.20431.34
    251 schema:familyName Chevalier
    252 schema:givenName Robert B.
    253 rdf:type schema:Person
    254 Nfd7a0b622cdf43c09278c8fecd023871 schema:name Nova Biomedical, 200 Prospect Street, 02454-9141, Waltham, MA, USA
    255 rdf:type schema:Organization
    256 anzsrc-for:03 schema:inDefinedTermSet anzsrc-for:
    257 schema:name Chemical Sciences
    258 rdf:type schema:DefinedTerm
    259 anzsrc-for:0303 schema:inDefinedTermSet anzsrc-for:
    260 schema:name Macromolecular and Materials Chemistry
    261 rdf:type schema:DefinedTerm
    262 sg:grant.3133026 http://pending.schema.org/fundedItem sg:pub.10.1007/s41664-019-00092-1
    263 rdf:type schema:MonetaryGrant
    264 sg:grant.7703871 http://pending.schema.org/fundedItem sg:pub.10.1007/s41664-019-00092-1
    265 rdf:type schema:MonetaryGrant
    266 sg:journal.1290430 schema:issn 2096-241X
    267 2509-4696
    268 schema:name Journal of Analysis and Testing
    269 rdf:type schema:Periodical
    270 sg:pub.10.1007/s00216-001-1189-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000886980
    271 https://doi.org/10.1007/s00216-001-1189-3
    272 rdf:type schema:CreativeWork
    273 sg:pub.10.1007/s00216-008-2412-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034004162
    274 https://doi.org/10.1007/s00216-008-2412-2
    275 rdf:type schema:CreativeWork
    276 sg:pub.10.1038/35084037 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045265151
    277 https://doi.org/10.1038/35084037
    278 rdf:type schema:CreativeWork
    279 sg:pub.10.1038/355564a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000063370
    280 https://doi.org/10.1038/355564a0
    281 rdf:type schema:CreativeWork
    282 sg:pub.10.1038/79275 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027719967
    283 https://doi.org/10.1038/79275
    284 rdf:type schema:CreativeWork
    285 sg:pub.10.1038/cdd.2013.50 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046171448
    286 https://doi.org/10.1038/cdd.2013.50
    287 rdf:type schema:CreativeWork
    288 sg:pub.10.1038/nature16996 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047444576
    289 https://doi.org/10.1038/nature16996
    290 rdf:type schema:CreativeWork
    291 sg:pub.10.1038/nature21901 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084128623
    292 https://doi.org/10.1038/nature21901
    293 rdf:type schema:CreativeWork
    294 sg:pub.10.1038/nbt.1495 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037155475
    295 https://doi.org/10.1038/nbt.1495
    296 rdf:type schema:CreativeWork
    297 sg:pub.10.1038/nbt1001-913 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051860859
    298 https://doi.org/10.1038/nbt1001-913
    299 rdf:type schema:CreativeWork
    300 sg:pub.10.1038/nbt1407 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034846157
    301 https://doi.org/10.1038/nbt1407
    302 rdf:type schema:CreativeWork
    303 sg:pub.10.1038/nchembio0609-368 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040044976
    304 https://doi.org/10.1038/nchembio0609-368
    305 rdf:type schema:CreativeWork
    306 sg:pub.10.1038/nmat1933 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043783923
    307 https://doi.org/10.1038/nmat1933
    308 rdf:type schema:CreativeWork
    309 sg:pub.10.1038/nmat941 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030841250
    310 https://doi.org/10.1038/nmat941
    311 rdf:type schema:CreativeWork
    312 sg:pub.10.1038/nmat965 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043496789
    313 https://doi.org/10.1038/nmat965
    314 rdf:type schema:CreativeWork
    315 sg:pub.10.1038/nmeth1021 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014966509
    316 https://doi.org/10.1038/nmeth1021
    317 rdf:type schema:CreativeWork
    318 sg:pub.10.1038/nnano.2009.379 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000093273
    319 https://doi.org/10.1038/nnano.2009.379
    320 rdf:type schema:CreativeWork
    321 sg:pub.10.1038/nnano.2011.12 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037237720
    322 https://doi.org/10.1038/nnano.2011.12
    323 rdf:type schema:CreativeWork
    324 sg:pub.10.1038/nnano.2015.320 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048522255
    325 https://doi.org/10.1038/nnano.2015.320
    326 rdf:type schema:CreativeWork
    327 sg:pub.10.1038/nnano.2016.267 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031235323
    328 https://doi.org/10.1038/nnano.2016.267
    329 rdf:type schema:CreativeWork
    330 sg:pub.10.1038/nrc3982 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036508003
    331 https://doi.org/10.1038/nrc3982
    332 rdf:type schema:CreativeWork
    333 sg:pub.10.1038/nrd2852 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003755355
    334 https://doi.org/10.1038/nrd2852
    335 rdf:type schema:CreativeWork
    336 sg:pub.10.1038/nrmicro1458 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000514347
    337 https://doi.org/10.1038/nrmicro1458
    338 rdf:type schema:CreativeWork
    339 sg:pub.10.1038/nrmicro841 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024064458
    340 https://doi.org/10.1038/nrmicro841
    341 rdf:type schema:CreativeWork
    342 sg:pub.10.1038/s41467-018-03439-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1101436482
    343 https://doi.org/10.1038/s41467-018-03439-x
    344 rdf:type schema:CreativeWork
    345 sg:pub.10.1038/s41467-018-05751-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1106100326
    346 https://doi.org/10.1038/s41467-018-05751-y
    347 rdf:type schema:CreativeWork
    348 sg:pub.10.1038/s41565-018-0236-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1106432298
    349 https://doi.org/10.1038/s41565-018-0236-6
    350 rdf:type schema:CreativeWork
    351 sg:pub.10.1038/s41598-017-18364-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1099733334
    352 https://doi.org/10.1038/s41598-017-18364-0
    353 rdf:type schema:CreativeWork
    354 sg:pub.10.1038/s41598-018-33086-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1107306582
    355 https://doi.org/10.1038/s41598-018-33086-7
    356 rdf:type schema:CreativeWork
    357 sg:pub.10.1038/srep01638 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007697893
    358 https://doi.org/10.1038/srep01638
    359 rdf:type schema:CreativeWork
    360 sg:pub.10.1186/1471-2105-8-s7-s9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029298906
    361 https://doi.org/10.1186/1471-2105-8-s7-s9
    362 rdf:type schema:CreativeWork
    363 sg:pub.10.2165/11530550-000000000-00000 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025543499
    364 https://doi.org/10.2165/11530550-000000000-00000
    365 rdf:type schema:CreativeWork
    366 https://app.dimensions.ai/details/publication/pub.1074515144 schema:CreativeWork
    367 https://doi.org/10.1002/adfm.201807555 schema:sameAs https://app.dimensions.ai/details/publication/pub.1110223990
    368 rdf:type schema:CreativeWork
    369 https://doi.org/10.1002/adma.201704680 schema:sameAs https://app.dimensions.ai/details/publication/pub.1106897463
    370 rdf:type schema:CreativeWork
    371 https://doi.org/10.1002/anie.201205687 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022008360
    372 rdf:type schema:CreativeWork
    373 https://doi.org/10.1002/cbic.200500064 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036358057
    374 rdf:type schema:CreativeWork
    375 https://doi.org/10.1002/cbic.200900526 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042880151
    376 rdf:type schema:CreativeWork
    377 https://doi.org/10.1002/elps.201400612 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032481811
    378 rdf:type schema:CreativeWork
    379 https://doi.org/10.1002/elps.201500561 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020999179
    380 rdf:type schema:CreativeWork
    381 https://doi.org/10.1002/elps.201700299 schema:sameAs https://app.dimensions.ai/details/publication/pub.1092655183
    382 rdf:type schema:CreativeWork
    383 https://doi.org/10.1002/smll.200700106 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036184351
    384 rdf:type schema:CreativeWork
    385 https://doi.org/10.1002/smll.200901435 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000351901
    386 rdf:type schema:CreativeWork
    387 https://doi.org/10.1002/smll.201000253 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046517910
    388 rdf:type schema:CreativeWork
    389 https://doi.org/10.1002/smll.201001428 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038308773
    390 rdf:type schema:CreativeWork
    391 https://doi.org/10.1002/smll.201303602 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002744639
    392 rdf:type schema:CreativeWork
    393 https://doi.org/10.1006/jmbi.1997.1275 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020188010
    394 rdf:type schema:CreativeWork
    395 https://doi.org/10.1016/j.bbrc.2011.07.121 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050069398
    396 rdf:type schema:CreativeWork
    397 https://doi.org/10.1016/j.bios.2012.05.013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041710109
    398 rdf:type schema:CreativeWork
    399 https://doi.org/10.1016/j.cis.2017.09.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1091733766
    400 rdf:type schema:CreativeWork
    401 https://doi.org/10.1016/j.copbio.2010.05.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013285653
    402 rdf:type schema:CreativeWork
    403 https://doi.org/10.1016/j.elecom.2013.09.009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043783467
    404 rdf:type schema:CreativeWork
    405 https://doi.org/10.1016/j.electacta.2010.03.051 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034586559
    406 rdf:type schema:CreativeWork
    407 https://doi.org/10.1016/j.nantod.2012.12.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035860670
    408 rdf:type schema:CreativeWork
    409 https://doi.org/10.1016/j.plrev.2012.05.010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050778379
    410 rdf:type schema:CreativeWork
    411 https://doi.org/10.1016/j.snb.2011.12.070 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048001547
    412 rdf:type schema:CreativeWork
    413 https://doi.org/10.1016/s0006-3495(02)75442-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053541079
    414 rdf:type schema:CreativeWork
    415 https://doi.org/10.1016/s0165-9936(03)01208-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023219987
    416 rdf:type schema:CreativeWork
    417 https://doi.org/10.1016/s0301-4622(99)00108-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006655249
    418 rdf:type schema:CreativeWork
    419 https://doi.org/10.1021/ac00109a003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1054972453
    420 rdf:type schema:CreativeWork
    421 https://doi.org/10.1021/ac101269u schema:sameAs https://app.dimensions.ai/details/publication/pub.1055000520
    422 rdf:type schema:CreativeWork
    423 https://doi.org/10.1021/ac200195n schema:sameAs https://app.dimensions.ai/details/publication/pub.1011570766
    424 rdf:type schema:CreativeWork
    425 https://doi.org/10.1021/ac2010857 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025516081
    426 rdf:type schema:CreativeWork
    427 https://doi.org/10.1021/ac300129e schema:sameAs https://app.dimensions.ai/details/publication/pub.1031308457
    428 rdf:type schema:CreativeWork
    429 https://doi.org/10.1021/ac4020929 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055004703
    430 rdf:type schema:CreativeWork
    431 https://doi.org/10.1021/ac403969n schema:sameAs https://app.dimensions.ai/details/publication/pub.1055005269
    432 rdf:type schema:CreativeWork
    433 https://doi.org/10.1021/ac501089m schema:sameAs https://app.dimensions.ai/details/publication/pub.1055016073
    434 rdf:type schema:CreativeWork
    435 https://doi.org/10.1021/ac502596m schema:sameAs https://app.dimensions.ai/details/publication/pub.1022753337
    436 rdf:type schema:CreativeWork
    437 https://doi.org/10.1021/ac504180h schema:sameAs https://app.dimensions.ai/details/publication/pub.1039901320
    438 rdf:type schema:CreativeWork
    439 https://doi.org/10.1021/ac504186m schema:sameAs https://app.dimensions.ai/details/publication/pub.1037026856
    440 rdf:type schema:CreativeWork
    441 https://doi.org/10.1021/ac9006705 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028681973
    442 rdf:type schema:CreativeWork
    443 https://doi.org/10.1021/acs.analchem.5b01167 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006902654
    444 rdf:type schema:CreativeWork
    445 https://doi.org/10.1021/acs.analchem.5b02611 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055078882
    446 rdf:type schema:CreativeWork
    447 https://doi.org/10.1021/acs.analchem.5b03347 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055079095
    448 rdf:type schema:CreativeWork
    449 https://doi.org/10.1021/acs.analchem.6b04260 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018324181
    450 rdf:type schema:CreativeWork
    451 https://doi.org/10.1021/acs.analchem.8b04136 schema:sameAs https://app.dimensions.ai/details/publication/pub.1109812859
    452 rdf:type schema:CreativeWork
    453 https://doi.org/10.1021/acsami.6b10045 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055131849
    454 rdf:type schema:CreativeWork
    455 https://doi.org/10.1021/acsami.6b12720 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055132514
    456 rdf:type schema:CreativeWork
    457 https://doi.org/10.1021/acsanm.7b00385 schema:sameAs https://app.dimensions.ai/details/publication/pub.1100522882
    458 rdf:type schema:CreativeWork
    459 https://doi.org/10.1021/acscentsci.7b00576 schema:sameAs https://app.dimensions.ai/details/publication/pub.1100422592
    460 rdf:type schema:CreativeWork
    461 https://doi.org/10.1021/acssensors.6b00564 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027952981
    462 rdf:type schema:CreativeWork
    463 https://doi.org/10.1021/am4026455 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045953260
    464 rdf:type schema:CreativeWork
    465 https://doi.org/10.1021/am501971n schema:sameAs https://app.dimensions.ai/details/publication/pub.1055145644
    466 rdf:type schema:CreativeWork
    467 https://doi.org/10.1021/am800121d schema:sameAs https://app.dimensions.ai/details/publication/pub.1036339080
    468 rdf:type schema:CreativeWork
    469 https://doi.org/10.1021/ar700229r schema:sameAs https://app.dimensions.ai/details/publication/pub.1055151723
    470 rdf:type schema:CreativeWork
    471 https://doi.org/10.1021/ar900165x schema:sameAs https://app.dimensions.ai/details/publication/pub.1032386937
    472 rdf:type schema:CreativeWork
    473 https://doi.org/10.1021/cb2004737 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055226111
    474 rdf:type schema:CreativeWork
    475 https://doi.org/10.1021/cb300449t schema:sameAs https://app.dimensions.ai/details/publication/pub.1055226272
    476 rdf:type schema:CreativeWork
    477 https://doi.org/10.1021/cr300381m schema:sameAs https://app.dimensions.ai/details/publication/pub.1038313680
    478 rdf:type schema:CreativeWork
    479 https://doi.org/10.1021/cr980099g schema:sameAs https://app.dimensions.ai/details/publication/pub.1026153115
    480 rdf:type schema:CreativeWork
    481 https://doi.org/10.1021/cr990343j schema:sameAs https://app.dimensions.ai/details/publication/pub.1053968440
    482 rdf:type schema:CreativeWork
    483 https://doi.org/10.1021/ja043910f schema:sameAs https://app.dimensions.ai/details/publication/pub.1024547443
    484 rdf:type schema:CreativeWork
    485 https://doi.org/10.1021/ja063485l schema:sameAs https://app.dimensions.ai/details/publication/pub.1028824814
    486 rdf:type schema:CreativeWork
    487 https://doi.org/10.1021/ja0739943 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007341840
    488 rdf:type schema:CreativeWork
    489 https://doi.org/10.1021/ja2026085 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052501552
    490 rdf:type schema:CreativeWork
    491 https://doi.org/10.1021/ja4053398 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053288285
    492 rdf:type schema:CreativeWork
    493 https://doi.org/10.1021/jm030176m schema:sameAs https://app.dimensions.ai/details/publication/pub.1055947958
    494 rdf:type schema:CreativeWork
    495 https://doi.org/10.1021/jp0775911 schema:sameAs https://app.dimensions.ai/details/publication/pub.1056074963
    496 rdf:type schema:CreativeWork
    497 https://doi.org/10.1021/jp305381j schema:sameAs https://app.dimensions.ai/details/publication/pub.1056090106
    498 rdf:type schema:CreativeWork
    499 https://doi.org/10.1021/la400716c schema:sameAs https://app.dimensions.ai/details/publication/pub.1056157817
    500 rdf:type schema:CreativeWork
    501 https://doi.org/10.1021/nl050925i schema:sameAs https://app.dimensions.ai/details/publication/pub.1029757745
    502 rdf:type schema:CreativeWork
    503 https://doi.org/10.1021/nl052107w schema:sameAs https://app.dimensions.ai/details/publication/pub.1012253571
    504 rdf:type schema:CreativeWork
    505 https://doi.org/10.1021/nl070462b schema:sameAs https://app.dimensions.ai/details/publication/pub.1013352629
    506 rdf:type schema:CreativeWork
    507 https://doi.org/10.1021/nl100861c schema:sameAs https://app.dimensions.ai/details/publication/pub.1006025111
    508 rdf:type schema:CreativeWork
    509 https://doi.org/10.1021/nl301412b schema:sameAs https://app.dimensions.ai/details/publication/pub.1030008858
    510 rdf:type schema:CreativeWork
    511 https://doi.org/10.1021/nl404183t schema:sameAs https://app.dimensions.ai/details/publication/pub.1023961623
    512 rdf:type schema:CreativeWork
    513 https://doi.org/10.1021/nl802218f schema:sameAs https://app.dimensions.ai/details/publication/pub.1008946858
    514 rdf:type schema:CreativeWork
    515 https://doi.org/10.1021/nn301125y schema:sameAs https://app.dimensions.ai/details/publication/pub.1056224322
    516 rdf:type schema:CreativeWork
    517 https://doi.org/10.1021/nn301672g schema:sameAs https://app.dimensions.ai/details/publication/pub.1056224409
    518 rdf:type schema:CreativeWork
    519 https://doi.org/10.1021/nn3031047 schema:sameAs https://app.dimensions.ai/details/publication/pub.1056224648
    520 rdf:type schema:CreativeWork
    521 https://doi.org/10.1021/nn303900y schema:sameAs https://app.dimensions.ai/details/publication/pub.1056224759
    522 rdf:type schema:CreativeWork
    523 https://doi.org/10.1021/nn3051677 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039769464
    524 rdf:type schema:CreativeWork
    525 https://doi.org/10.1021/nn401759r schema:sameAs https://app.dimensions.ai/details/publication/pub.1056225253
    526 rdf:type schema:CreativeWork
    527 https://doi.org/10.1021/nn405045x schema:sameAs https://app.dimensions.ai/details/publication/pub.1025900472
    528 rdf:type schema:CreativeWork
    529 https://doi.org/10.1021/nn5042398 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047632012
    530 rdf:type schema:CreativeWork
    531 https://doi.org/10.1021/nn506572r schema:sameAs https://app.dimensions.ai/details/publication/pub.1007502029
    532 rdf:type schema:CreativeWork
    533 https://doi.org/10.1021/nn900713a schema:sameAs https://app.dimensions.ai/details/publication/pub.1043712272
    534 rdf:type schema:CreativeWork
    535 https://doi.org/10.1039/b504827c schema:sameAs https://app.dimensions.ai/details/publication/pub.1016163254
    536 rdf:type schema:CreativeWork
    537 https://doi.org/10.1039/b607360c schema:sameAs https://app.dimensions.ai/details/publication/pub.1037488044
    538 rdf:type schema:CreativeWork
    539 https://doi.org/10.1039/b708725j schema:sameAs https://app.dimensions.ai/details/publication/pub.1027637706
    540 rdf:type schema:CreativeWork
    541 https://doi.org/10.1039/b813796j schema:sameAs https://app.dimensions.ai/details/publication/pub.1005776619
    542 rdf:type schema:CreativeWork
    543 https://doi.org/10.1039/b819896a schema:sameAs https://app.dimensions.ai/details/publication/pub.1024172237
    544 rdf:type schema:CreativeWork
    545 https://doi.org/10.1039/b900409m schema:sameAs https://app.dimensions.ai/details/publication/pub.1031648657
    546 rdf:type schema:CreativeWork
    547 https://doi.org/10.1039/b9nr00275h schema:sameAs https://app.dimensions.ai/details/publication/pub.1027381592
    548 rdf:type schema:CreativeWork
    549 https://doi.org/10.1039/c0cc02649b schema:sameAs https://app.dimensions.ai/details/publication/pub.1037502556
    550 rdf:type schema:CreativeWork
    551 https://doi.org/10.1039/c0cs00053a schema:sameAs https://app.dimensions.ai/details/publication/pub.1026644173
    552 rdf:type schema:CreativeWork
    553 https://doi.org/10.1039/c1nr00003a schema:sameAs https://app.dimensions.ai/details/publication/pub.1021748414
    554 rdf:type schema:CreativeWork
    555 https://doi.org/10.1039/c2cc17277a schema:sameAs https://app.dimensions.ai/details/publication/pub.1028397297
    556 rdf:type schema:CreativeWork
    557 https://doi.org/10.1039/c2cs35286a schema:sameAs https://app.dimensions.ai/details/publication/pub.1008476698
    558 rdf:type schema:CreativeWork
    559 https://doi.org/10.1039/c3lc50069a schema:sameAs https://app.dimensions.ai/details/publication/pub.1001986324
    560 rdf:type schema:CreativeWork
    561 https://doi.org/10.1039/c3nr02105j schema:sameAs https://app.dimensions.ai/details/publication/pub.1052108454
    562 rdf:type schema:CreativeWork
    563 https://doi.org/10.1039/c4an01439a schema:sameAs https://app.dimensions.ai/details/publication/pub.1028909240
    564 rdf:type schema:CreativeWork
    565 https://doi.org/10.1039/c5an00075k schema:sameAs https://app.dimensions.ai/details/publication/pub.1037223398
    566 rdf:type schema:CreativeWork
    567 https://doi.org/10.1039/c6lc01173j schema:sameAs https://app.dimensions.ai/details/publication/pub.1034969996
    568 rdf:type schema:CreativeWork
    569 https://doi.org/10.1039/c6nr07339e schema:sameAs https://app.dimensions.ai/details/publication/pub.1035609121
    570 rdf:type schema:CreativeWork
    571 https://doi.org/10.1056/nejmoa0803200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004063974
    572 rdf:type schema:CreativeWork
    573 https://doi.org/10.1063/1.1404988 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049354159
    574 rdf:type schema:CreativeWork
    575 https://doi.org/10.1063/1.1684724 schema:sameAs https://app.dimensions.ai/details/publication/pub.1057760416
    576 rdf:type schema:CreativeWork
    577 https://doi.org/10.1063/1.3521411 schema:sameAs https://app.dimensions.ai/details/publication/pub.1057967116
    578 rdf:type schema:CreativeWork
    579 https://doi.org/10.1063/1.4794973 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013728574
    580 rdf:type schema:CreativeWork
    581 https://doi.org/10.1063/1.4921620 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036116999
    582 rdf:type schema:CreativeWork
    583 https://doi.org/10.1063/1.4948525 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032011820
    584 rdf:type schema:CreativeWork
    585 https://doi.org/10.1073/pnas.0911450106 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019576041
    586 rdf:type schema:CreativeWork
    587 https://doi.org/10.1073/pnas.1001831107 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014637542
    588 rdf:type schema:CreativeWork
    589 https://doi.org/10.1073/pnas.1002194107 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052252626
    590 rdf:type schema:CreativeWork
    591 https://doi.org/10.1073/pnas.93.24.13770 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016336761
    592 rdf:type schema:CreativeWork
    593 https://doi.org/10.1088/0953-8984/22/45/450301 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049534002
    594 rdf:type schema:CreativeWork
    595 https://doi.org/10.1088/0953-8984/22/45/454104 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050470100
    596 rdf:type schema:CreativeWork
    597 https://doi.org/10.1088/0953-8984/22/45/454133 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044582000
    598 rdf:type schema:CreativeWork
    599 https://doi.org/10.1088/0957-4484/18/30/305505 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040789246
    600 rdf:type schema:CreativeWork
    601 https://doi.org/10.1088/0957-4484/21/14/145102 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028137039
    602 rdf:type schema:CreativeWork
    603 https://doi.org/10.1088/0957-4484/22/31/315101 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028867644
    604 rdf:type schema:CreativeWork
    605 https://doi.org/10.1088/0957-4484/23/40/405301 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047112434
    606 rdf:type schema:CreativeWork
    607 https://doi.org/10.1088/0957-4484/23/43/435301 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012182887
    608 rdf:type schema:CreativeWork
    609 https://doi.org/10.1088/0960-1317/25/1/015011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025224032
    610 rdf:type schema:CreativeWork
    611 https://doi.org/10.1093/glycob/cwn026 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001710377
    612 rdf:type schema:CreativeWork
    613 https://doi.org/10.1103/physrevlett.102.256804 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060755594
    614 rdf:type schema:CreativeWork
    615 https://doi.org/10.1103/physrevlett.109.024501 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060760047
    616 rdf:type schema:CreativeWork
    617 https://doi.org/10.1103/physrevlett.93.035901 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040946543
    618 rdf:type schema:CreativeWork
    619 https://doi.org/10.1103/revmodphys.80.839 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060839667
    620 rdf:type schema:CreativeWork
    621 https://doi.org/10.1109/84.546406 schema:sameAs https://app.dimensions.ai/details/publication/pub.1061240560
    622 rdf:type schema:CreativeWork
    623 https://doi.org/10.1126/science.1151298 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044477038
    624 rdf:type schema:CreativeWork
    625 https://doi.org/10.1126/science.1225624 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030772710
    626 rdf:type schema:CreativeWork
    627 https://doi.org/10.1126/science.1235681 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034393517
    628 rdf:type schema:CreativeWork
    629 https://doi.org/10.1126/science.274.5294.1859 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062555213
    630 rdf:type schema:CreativeWork
    631 https://doi.org/10.1126/science.291.5512.2364 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062573344
    632 rdf:type schema:CreativeWork
    633 https://doi.org/10.1126/science.291.5512.2370 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062573345
    634 rdf:type schema:CreativeWork
    635 https://doi.org/10.1177/0003702817715496 schema:sameAs https://app.dimensions.ai/details/publication/pub.1086055048
    636 rdf:type schema:CreativeWork
    637 https://doi.org/10.1177/153537020623100211 schema:sameAs https://app.dimensions.ai/details/publication/pub.1077181934
    638 rdf:type schema:CreativeWork
    639 https://doi.org/10.1209/0295-5075/82/48003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064232057
    640 rdf:type schema:CreativeWork
    641 https://doi.org/10.1371/journal.pone.0054982 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010514425
    642 rdf:type schema:CreativeWork
    643 https://doi.org/10.1371/journal.pone.0092880 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027623543
    644 rdf:type schema:CreativeWork
    645 https://doi.org/10.1529/biophysj.104.040212 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048744447
    646 rdf:type schema:CreativeWork
    647 https://doi.org/10.1529/biophysj.104.047274 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022535175
    648 rdf:type schema:CreativeWork
    649 https://doi.org/10.1529/biophysj.104.057406 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018863347
    650 rdf:type schema:CreativeWork
    651 https://doi.org/10.1529/biophysj.105.079111 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015056699
    652 rdf:type schema:CreativeWork
    653 https://doi.org/10.1529/biophysj.106.094060 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038919191
    654 rdf:type schema:CreativeWork
    655 https://doi.org/10.1529/biophysj.106.102855 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053058515
    656 rdf:type schema:CreativeWork
    657 https://doi.org/10.1529/biophysj.108.137760 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007694232
    658 rdf:type schema:CreativeWork
    659 https://doi.org/10.1529/biophysj.108.140475 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039688081
    660 rdf:type schema:CreativeWork
    661 https://doi.org/10.2217/17435889.2.4.459 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003026977
    662 rdf:type schema:CreativeWork
    663 https://doi.org/10.2217/17435889.2.6.875 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001374857
    664 rdf:type schema:CreativeWork
    665 https://www.grid.ac/institutes/grid.20431.34 schema:alternateName University of Rhode Island
    666 schema:name Department of Chemistry, University of Rhode Island, Richard E. Beaupre Center for Chemical and Forensic Sciences, 140 Flagg Rd., 02881, Kingston, RI, USA
    667 rdf:type schema:Organization
    668 https://www.grid.ac/institutes/grid.263864.d schema:alternateName Southern Methodist University
    669 schema:name Department of Mechanical Engineering, Lyle School of Engineering, Southern Methodist University, 75275, Dallas, TX, USA
    670 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...