Recommendations for treatment of hypothyroidism with levothyroxine and levotriiodothyronine: a 2016 position statement of the Italian Society of Endocrinology and ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2016-12

AUTHORS

B. Biondi, L. Bartalena, L. Chiovato, A. Lenzi, S. Mariotti, F. Pacini, A. Pontecorvi, P. Vitti, F. Trimarchi

ABSTRACT

Levothyroxine (L-T4) is recommended as lifelong replacement therapy for hypothyroidism. Recent clinical and experimental data support the addition of levotriiodothyronine (L-T3) treatment in some selected hypothyroid patients when their symptoms persist and their quality of life remains impaired despite adequate L-T4 monotherapy. An increase in L-T3 prescriptions has been recently observed in Italy due to availability of different L-T3 formulations, making it possible to clinicians to prescribe L-T3 alone or in combination with L-T4. The aim of the present position statement was to define the correct clinical indications, schedule, duration of treatment and contraindications of combined treatment with L-T4 and L-T3 in hypothyroid patients in an attempt to guide clinicians and to avoid potential adverse effects of overtreatment. More... »

PAGES

1465-1474

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s40618-016-0511-z

DOI

http://dx.doi.org/10.1007/s40618-016-0511-z

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1016772003

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/27473077


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