A Timeout on the Antimicrobial Timeout: Where Does It Stand and What Is Its Future? View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2018-02-07

AUTHORS

Patrick Kinn, Michael Postelnick, Stephanie Schroeder, Lucas T Schulz

ABSTRACT

Opinion statementPurpose of reviewTo summarize literature describing the antimicrobial timeout, its rationale for use as an antimicrobial stewardship program (ASP) strategy, and its potential role in overall ASP strategy.Recent findingsStudies have correlated a formal antimicrobial timeout process with increased rates of therapy modification and reductions in use of select broad-spectrum antibiotics. There remains a need for further guidance on how to best implement a system-wide antimicrobial timeout.SummaryThe antimicrobial timeout is a stewardship tool that protocolizes review of objective clinical data and encourages stewardship practices, such as antimicrobial de-escalation, parenteral-to-enteral route interchange, dose optimization, and appropriate duration. Logically, the timeout encourages thoughtful reassessment of antimicrobial therapy and should produce positive antimicrobial utilization outcomes; however, clinical effectiveness data is conflicting, with more research necessary. Institutions should implement standardized processes by which their clinical services evaluate and thoughtfully assess use of antimicrobials among their patients whether they are being treated in the hospital or possibly, at home. Implementation of a formal timeout may allow a greater sharing of responsibility for antimicrobial stewardship among formal members of stewardship programs and front-line clinicians. More... »

PAGES

281-290

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s40506-018-0146-z

DOI

http://dx.doi.org/10.1007/s40506-018-0146-z

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1100859794


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