Abdominal Wall Transplantation View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2015-09

AUTHORS

Yash J. Avashia, Gina A. Mackert, Brian May, Detlev Erdmann, Kadiyala V. Ravindra

ABSTRACT

Abdominal wall vascularized composite allotransplantation (AW-VCA) is a relatively young field within transplantation with 21 reported cases to date in the last decade. All AW-VCAs have been performed on patients undergoing either simultaneous multivisceral transplantation (MVT) or intestinal transplantation (IT). The two approaches to AW-VCA described are macrovascular and microvascular approaches. While at the time that this review is written, only three institutions have performed this procedure; their outcomes have shown low allograft loss. In addition, acute rejection of the abdominal wall graft was uncommon and successfully treated with standard measures. A comparison of each institution’s operative technique, maintenance immunosuppression regimen, and rejection management provide insight regarding the feasibility of AW-VCAs. AW-VCA has proven to serve as a viable option for patients undergoing multivisceral or intestinal transplantation with a donor and recipient size mismatch. Further experience with AW-VCA will aid in better defining its indications and help standardize technique and management. More... »

PAGES

269-275

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s40472-015-0070-9

DOI

http://dx.doi.org/10.1007/s40472-015-0070-9

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1024538964


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39 schema:description Abdominal wall vascularized composite allotransplantation (AW-VCA) is a relatively young field within transplantation with 21 reported cases to date in the last decade. All AW-VCAs have been performed on patients undergoing either simultaneous multivisceral transplantation (MVT) or intestinal transplantation (IT). The two approaches to AW-VCA described are macrovascular and microvascular approaches. While at the time that this review is written, only three institutions have performed this procedure; their outcomes have shown low allograft loss. In addition, acute rejection of the abdominal wall graft was uncommon and successfully treated with standard measures. A comparison of each institution’s operative technique, maintenance immunosuppression regimen, and rejection management provide insight regarding the feasibility of AW-VCAs. AW-VCA has proven to serve as a viable option for patients undergoing multivisceral or intestinal transplantation with a donor and recipient size mismatch. Further experience with AW-VCA will aid in better defining its indications and help standardize technique and management.
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