Effect of Primary Hypertension on Treatment Outcomes of Patients with Postmenopausal Osteoporosis: A 5 Year Follow Up Retrospective Study View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2018-11-22

AUTHORS

Volkan Yilmaz, Ebru Umay, Ibrahim Gundogdu, Fatma Aytul Cakcı

ABSTRACT

AimTo investigate the efficacy of primary hypertension (HTN) on the treatment prognosis of patients with postmenopausal osteoporosis (PMOP).Methods45 patients who were diagnosed as PMOP with lumbar and/or femur neck bone mineral density screening (BMD) but have no history of PMOP treatment including calcium and vitamin D, have comorbid primary HTN and treated with a vasodilator antihypertensive drug at least a year were included to the study. Control group was constituted with 44 patients with PMOP at same age but have no comorbidity. Demographic features including age, height, weight, occupation, educational level menarche and menopause age, clothing style, daily intake of calcium, smoking and/or alcohol consumption, daily physical activity level, personal history of fragility fracture or in mother and duration of primary HTN diagnosis were recorded. Biochemical parameters were also recorded. Patients were treated with bisphosphonate, calcium and vitamin D and same parameters were evaluated at the end of first and fifth year.ResultsDemographic and disease characteristics were not different between groups before treatment (p > 0.05). In group analysis, there was significant improvement in lumbar and femur neck T scores of PMOP + HT and PMOP groups after 1 and 5 years of treatment compared to baseline (p < 0.05) Lumbar and femur neck T score variations between the baseline, first and fifth years of treatment were not significantly different in PMOP + HT and PMOP groups (p < 0.05).ConclusionsAlthough the results vary between populations, primary HTN does not have an impact on the prognosis of PMOP treatment in Turkish population. More... »

PAGES

61-67

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s40292-018-0291-y

DOI

http://dx.doi.org/10.1007/s40292-018-0291-y

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1110133119

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30467637


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