Ontology type: schema:ScholarlyArticle Open Access: True
2018-02
AUTHORSMette Heringa, Annemieke Floor-Schreudering, Hans Wouters, Peter A. G. M. De Smet, Marcel L. Bouvy
ABSTRACTINTRODUCTION: The management of drug-drug interactions (DDIs) is a complex process in which risk-benefit assessments should be combined with the patient's perspective. OBJECTIVE: The aim of this study was to determine patients' and pharmacists' preferences regarding DDI management. METHODS: We conducted a choice-based conjoint survey about a fictitious DDI concerning the combination of a cardiovascular drug and an antibiotic for pneumonia. Patients and pharmacists had to choose 12 times between two management options. The options were described by five attributes, including risk, benefit and practical consequences. Each attribute could have two different levels, which were varied over the choice tasks. Latent class analysis was used to identify potential classes of respondents with distinct patterns of similar preferences. RESULTS: In total, 298 patients and 178 pharmacists completed the questionnaire. The latent class model for both patients and pharmacists resulted in three classes. For patients, in one class the most importance was attached to avoiding switch of medication (class probability 20%), in a second class to fewer adverse events (41%), and in a third class to blood sampling (39%). For pharmacists, again one class attached the highest importance to avoiding switch of medication (31%). The other classes gave priority to curing pneumonia (31%) and avoiding blood sampling (38%). CONCLUSION: The results showed diverging preferences regarding DDI management among both patients and pharmacists. Different groups attached different value to risk and benefit versus practical considerations. Awareness of existing variability in preferences among and between pharmacists and patients is a step towards shared decision making in DDI management. More... »
PAGES179-189
http://scigraph.springernature.com/pub.10.1007/s40264-017-0601-7
DOIhttp://dx.doi.org/10.1007/s40264-017-0601-7
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1092001961
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/28965265
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Clinical Sciences",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Medical and Health Sciences",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Anti-Bacterial Agents",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Cardiovascular Agents",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Drug Interactions",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Drug-Related Side Effects and Adverse Reactions",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Female",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Humans",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Male",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Middle Aged",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Pharmacists",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Pneumonia",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Risk",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Surveys and Questionnaires",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "Utrecht University",
"id": "https://www.grid.ac/institutes/grid.5477.1",
"name": [
"SIR Institute for Pharmacy Practice and Policy, Theda Mansholtstraat 5B, 2331 JE, Leiden, The Netherlands",
"Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands",
"Health Base Foundation, Houten, The Netherlands"
],
"type": "Organization"
},
"familyName": "Heringa",
"givenName": "Mette",
"id": "sg:person.01115203500.03",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01115203500.03"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Utrecht University",
"id": "https://www.grid.ac/institutes/grid.5477.1",
"name": [
"SIR Institute for Pharmacy Practice and Policy, Theda Mansholtstraat 5B, 2331 JE, Leiden, The Netherlands",
"Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands"
],
"type": "Organization"
},
"familyName": "Floor-Schreudering",
"givenName": "Annemieke",
"id": "sg:person.01260465553.31",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01260465553.31"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Groningen",
"id": "https://www.grid.ac/institutes/grid.4830.f",
"name": [
"Department of Pharmacotherapy, -Epidemiology and -Economics, Groningen University, Groningen, The Netherlands"
],
"type": "Organization"
},
"familyName": "Wouters",
"givenName": "Hans",
"id": "sg:person.01005720575.12",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01005720575.12"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Radboud University Nijmegen Medical Centre",
"id": "https://www.grid.ac/institutes/grid.10417.33",
"name": [
"Departments of Clinical Pharmacy and IQ Healthcare, University Medical Centre St Radboud, Nijmegen, The Netherlands"
],
"type": "Organization"
},
"familyName": "De Smet",
"givenName": "Peter A. G. M.",
"id": "sg:person.0701513410.65",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0701513410.65"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Utrecht University",
"id": "https://www.grid.ac/institutes/grid.5477.1",
"name": [
"SIR Institute for Pharmacy Practice and Policy, Theda Mansholtstraat 5B, 2331 JE, Leiden, The Netherlands",
"Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands"
],
"type": "Organization"
},
"familyName": "Bouvy",
"givenName": "Marcel L.",
"id": "sg:person.0661624471.77",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0661624471.77"
],
"type": "Person"
}
],
"citation": [
{
"id": "https://doi.org/10.1177/0272989x16683934",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1001994468"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1177/0272989x16683934",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1001994468"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1177/0272989x10391672",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1002828299"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1177/0272989x10391672",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1002828299"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1037/a0022723",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1002931714"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1136/bmj.e256",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1004050681"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1080/10810730802202169",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1009149337"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.jclinepi.2015.11.017",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1011221746"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s40264-014-0262-8",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1011280266",
"https://doi.org/10.1007/s40264-014-0262-8"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.2337/dc07-1932",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1013763474"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.urolonc.2007.12.006",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1014053064"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.pec.2014.11.004",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1015777120"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.pec.2015.05.004",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1016532901"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.pec.2015.04.007",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1017265410"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00228-013-1612-7",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1018579537",
"https://doi.org/10.1007/s00228-013-1612-7"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.pec.2012.07.014",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1019197264"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1177/0272989x15584332",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1020941842"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1177/0272989x15584332",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1020941842"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1186/1472-6947-13-s2-s7",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1024656289",
"https://doi.org/10.1186/1472-6947-13-s2-s7"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1177/0272989x07303824",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1028783793"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1177/0272989x07303824",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1028783793"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.jval.2010.11.013",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1030781921"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/cpt.332",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1031582725"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1136/bmj.i2089",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1033178443"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.socscimed.2012.11.020",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1034690813"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1136/bmjqs-2012-001502",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1035322559"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1136/bmjqs-2012-001502",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1035322559"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.jval.2012.08.2223",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1037115565"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.pec.2010.07.027",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1037395954"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s11096-014-9954-5",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1039538552",
"https://doi.org/10.1007/s11096-014-9954-5"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1177/0272989x08327492",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1039995204"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1177/0272989x08327492",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1039995204"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1136/bmj.39493.646875.ae",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1042483764"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s11096-015-0221-1",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043094793",
"https://doi.org/10.1007/s11096-015-0221-1"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/hec.1369",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043569065"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1634/theoncologist.2010-s1-5",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043933903"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.pec.2010.05.021",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1046710565"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1136/bmj.g3725",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1047790732"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/pds.3915",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1048539455"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.jval.2016.04.004",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1049866368"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1177/0272989x07304449",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1050186032"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1177/0272989x07304449",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1050186032"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.socscimed.2014.10.024",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1051706100"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/hec.1104",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1052305668"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1136/bmj.e3996",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1052549100"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/jamia/ocv011",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1059743912"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/rheumatology/kew280",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1060012851"
],
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1079272255",
"type": "CreativeWork"
}
],
"datePublished": "2018-02",
"datePublishedReg": "2018-02-01",
"description": "INTRODUCTION: The management of drug-drug interactions (DDIs) is a complex process in which risk-benefit assessments should be combined with the patient's perspective.\nOBJECTIVE: The aim of this study was to determine patients' and pharmacists' preferences regarding DDI management.\nMETHODS: We conducted a choice-based conjoint survey about a fictitious DDI concerning the combination of a cardiovascular drug and an antibiotic for pneumonia. Patients and pharmacists had to choose 12 times between two management options. The options were described by five attributes, including risk, benefit and practical consequences. Each attribute could have two different levels, which were varied over the choice tasks. Latent class analysis was used to identify potential classes of respondents with distinct patterns of similar preferences.\nRESULTS: In total, 298 patients and 178 pharmacists completed the questionnaire. The latent class model for both patients and pharmacists resulted in three classes. For patients, in one class the most importance was attached to avoiding switch of medication (class probability 20%), in a second class to fewer adverse events (41%), and in a third class to blood sampling (39%). For pharmacists, again one class attached the highest importance to avoiding switch of medication (31%). The other classes gave priority to curing pneumonia (31%) and avoiding blood sampling (38%).\nCONCLUSION: The results showed diverging preferences regarding DDI management among both patients and pharmacists. Different groups attached different value to risk and benefit versus practical considerations. Awareness of existing variability in preferences among and between pharmacists and patients is a step towards shared decision making in DDI management.",
"genre": "research_article",
"id": "sg:pub.10.1007/s40264-017-0601-7",
"inLanguage": [
"en"
],
"isAccessibleForFree": true,
"isPartOf": [
{
"id": "sg:journal.1096281",
"issn": [
"0114-5916",
"1179-1942"
],
"name": "Drug Safety",
"type": "Periodical"
},
{
"issueNumber": "2",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "41"
}
],
"name": "Preferences of Patients and Pharmacists with Regard to the Management of Drug\u2013Drug Interactions: A Choice-Based Conjoint Analysis",
"pagination": "179-189",
"productId": [
{
"name": "readcube_id",
"type": "PropertyValue",
"value": [
"9bdd48627bd8aeb46933e128a5d73c2025693c455e33cc3463271ba22e320f34"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"28965265"
]
},
{
"name": "nlm_unique_id",
"type": "PropertyValue",
"value": [
"9002928"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1007/s40264-017-0601-7"
]
},
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1092001961"
]
}
],
"sameAs": [
"https://doi.org/10.1007/s40264-017-0601-7",
"https://app.dimensions.ai/details/publication/pub.1092001961"
],
"sdDataset": "articles",
"sdDatePublished": "2019-04-10T20:04",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8681_00000555.jsonl",
"type": "ScholarlyArticle",
"url": "https://link.springer.com/10.1007%2Fs40264-017-0601-7"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s40264-017-0601-7'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s40264-017-0601-7'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s40264-017-0601-7'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s40264-017-0601-7'
This table displays all metadata directly associated to this object as RDF triples.
280 TRIPLES
21 PREDICATES
82 URIs
33 LITERALS
21 BLANK NODES