Psychiatric and Cognitive Symptoms Associated with Niemann-Pick Type C Disease: Neurobiology and Management View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-02

AUTHORS

Thomas Rego, Sarah Farrand, Anita M. Y. Goh, Dhamidhu Eratne, Wendy Kelso, Simone Mangelsdorf, Dennis Velakoulis, Mark Walterfang

ABSTRACT

Niemann-Pick disease type C (NPC) is a lysosomal storage disorder that presents with a spectrum of clinical manifestations from infancy and childhood or in early or mid-adulthood. Progressive neurological symptoms including ataxia, dystonia and vertical gaze palsy are a hallmark of the disease, and psychiatric symptoms such as psychosis and mood disorders are common. These latter symptoms often present early in the course of NPC and thus these patients are often diagnosed with a major psychotic or affective disorder before neurological and cognitive signs present and the diagnosis is revised. The commonalities and characteristics of psychotic symptoms in both NPC and schizophrenia may share neuronal pathways and mechanisms and provide potential targets for research in both disorders. The neurobiology of NPC and its relationship to the pattern of neuropsychiatric and cognitive symptoms is described in this review. A number of neurobiological models are proposed as mechanisms by which NPC causes psychiatric and cognitive symptoms, informed from models proposed in schizophrenia and other metabolic disorders. There are a number of symptomatic and illness-modifying treatments for NPC currently available. The current evidence is discussed; focussing on two medications which have shown promise, miglustat and hydroxypropyl-β-cyclodextrin. More... »

PAGES

125-142

References to SciGraph publications

  • 2010-12. Niemann-Pick disease type C in ORPHANET JOURNAL OF RARE DISEASES
  • 2016-12. Altered localization and functionality of TAR DNA Binding Protein 43 (TDP-43) in niemann- pick disease type C in ACTA NEUROPATHOLOGICA COMMUNICATIONS
  • 2013-02. Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy in NATURE REVIEWS NEUROLOGY
  • 2018-12. Miglustat in Niemann-Pick disease type C patients: a review in ORPHANET JOURNAL OF RARE DISEASES
  • 1993-01. Cerebellar degeneration in the Niemann-Pick type C mouse in ACTA NEUROPATHOLOGICA
  • 1995-03. Neurofibrillary tangles in Niemann-Pick disease type C in ACTA NEUROPATHOLOGICA
  • 2006-07. The primate cortico-cerebellar system: anatomy and function in NATURE REVIEWS NEUROSCIENCE
  • 2013-12. Disease and patient characteristics in NP-C patients: findings from an international disease registry in ORPHANET JOURNAL OF RARE DISEASES
  • 2002-11. Niemann–Pick disease type C in adults in JOURNAL OF INHERITED METABOLIC DISEASE
  • 2015-12. Longitudinal assessment of reflexive and volitional saccades in Niemann-Pick Type C disease during treatment with miglustat in ORPHANET JOURNAL OF RARE DISEASES
  • 2007-09. Cerebellar involvement in executive control in THE CEREBELLUM
  • 2015-12. Long term follow-up to evaluate the efficacy of miglustat treatment in Italian patients with Niemann-Pick disease type C in ORPHANET JOURNAL OF RARE DISEASES
  • 2016-01. High incidence of unrecognized visceral/neurological late-onset Niemann-Pick disease, type C1, predicted by analysis of massively parallel sequencing data sets in GENETICS IN MEDICINE
  • 2016-12. Ataxia, dystonia and myoclonus in adult patients with Niemann-Pick type C in ORPHANET JOURNAL OF RARE DISEASES
  • 1995-12. Paired helical filament tau (PHFtau) in Niemann-Pick type C disease is similar to PHFtau in Alzheimer's disease in ACTA NEUROPATHOLOGICA
  • 2009-12. Gender dimorphism in siblings with schizophrenia-like psychosis due to Niemann-Pick disease type C in JOURNAL OF INHERITED METABOLIC DISEASE
  • 2017-12. Evolution of structural neuroimaging biomarkers in a series of adult patients with Niemann-Pick type C under treatment in ORPHANET JOURNAL OF RARE DISEASES
  • 2007-10. Treatment of Niemann–Pick disease type C in two children with miglustat: Initial responses and maintenance of effects over 1 year in JOURNAL OF INHERITED METABOLIC DISEASE
  • 2008-12. Treatment of a child diagnosed with Niemann–Pick disease type C with miglustat: A case report in Brazil in JOURNAL OF INHERITED METABOLIC DISEASE
  • 2002-05. Hippocampal neurons in schizophrenia in JOURNAL OF NEURAL TRANSMISSION
  • 2009-09. Niemann–Pick disease type C1 presenting with psychosis in an adolescent male in EUROPEAN CHILD & ADOLESCENT PSYCHIATRY
  • 2015-12. Observational cohort study of the natural history of Niemann-Pick disease type C in the UK: a 5-year update from the UK clinical database in BMC NEUROLOGY
  • 2017-05. Early experience with compassionate use of 2 hydroxypropyl-beta-cyclodextrin for Niemann–Pick type C disease: review of initial published cases in NEUROLOGICAL SCIENCES
  • 2013-01. Long-term efficacy of miglustat in paediatric patients with Niemann-Pick disease type C in JOURNAL OF INHERITED METABOLIC DISEASE
  • 2000-10. Regional distribution of NPC1 protein in monkey brain in BRAIN CELL BIOLOGY
  • 2018-12. Phenotypic variability of Niemann-Pick disease type C including a case with clinically pure schizophrenia: a case report in BMC NEUROLOGY
  • 2015-09. Longitudinal changes in cerebellar and subcortical volumes in adult-onset Niemann–Pick disease type C patients treated with miglustat in JOURNAL OF NEUROLOGY
  • 2014-12. Psychosis in an adolescent girl: a common manifestation in Niemann-Pick Type C disease in CHILD AND ADOLESCENT PSYCHIATRY AND MENTAL HEALTH
  • 2009-01. Perceiving is believing: a Bayesian approach to explaining the positive symptoms of schizophrenia in NATURE REVIEWS NEUROSCIENCE
  • 2015-12. An evaluation of variation in published estimates of schizophrenia prevalence from 1990─2013: a systematic literature review in BMC PSYCHIATRY
  • 2017-12. Thalamic functions in distributed cognitive control in NATURE NEUROSCIENCE
  • 2017. Longitudinal Changes in White Matter Fractional Anisotropy in Adult-Onset Niemann-Pick Disease Type C Patients Treated with Miglustat in JIMD REPORTS, VOLUME 39
  • 2017-12. Cognitive impairment profile in adult patients with Niemann pick type C disease in ORPHANET JOURNAL OF RARE DISEASES
  • 2009-10. Neurometabolic disorders in JOURNAL OF INHERITED METABOLIC DISEASE
  • 2008-08. Corollary discharge across the animal kingdom in NATURE REVIEWS NEUROSCIENCE
  • 2013-12. MRI characterisation of adult onset alpha-methylacyl-coA racemase deficiency diagnosed by exome sequencing in ORPHANET JOURNAL OF RARE DISEASES
  • 2003-03. Mapping cortical change across the human life span in NATURE NEUROSCIENCE
  • 2018-08. Hippocampal dysfunction in the pathophysiology of schizophrenia: a selective review and hypothesis for early detection and intervention in MOLECULAR PSYCHIATRY
  • 2007-10. Psychiatric manifestations revealing inborn errors of metabolism in adolescents and adults in JOURNAL OF INHERITED METABOLIC DISEASE
  • 2014-12. Observational, retrospective study of a large cohort of patients with Niemann-Pick disease type C in the Czech Republic: a surprisingly stable diagnostic rate spanning almost 40 years in ORPHANET JOURNAL OF RARE DISEASES
  • 2018-12. Distinguishing neurocognitive deficits in adult patients with NP-C from early onset Alzheimer’s dementia in ORPHANET JOURNAL OF RARE DISEASES
  • 2014-12. Diagnostic and treatment implications of psychosis secondary to treatable metabolic disorders in adults: a systematic review in ORPHANET JOURNAL OF RARE DISEASES
  • 2007-02. Neuropsychological profile of adult patients with Niemann–Pick C1 (NPC1) mutations in JOURNAL OF INHERITED METABOLIC DISEASE
  • 2015-01. Complex lipid trafficking in Niemann-Pick disease type C in JOURNAL OF INHERITED METABOLIC DISEASE
  • 2010-12. Post-ictal psychosis in adolescent Niemann-Pick disease type C in JOURNAL OF INHERITED METABOLIC DISEASE
  • 2013-07. The neuropsychiatry of inborn errors of metabolism in JOURNAL OF INHERITED METABOLIC DISEASE
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s40263-018-0599-0

    DOI

    http://dx.doi.org/10.1007/s40263-018-0599-0

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1111314817

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/30632019


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Clinical Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Medical and Health Sciences", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "University of Melbourne", 
              "id": "https://www.grid.ac/institutes/grid.1008.9", 
              "name": [
                "Neuropsychiatry Unit, The Royal Melbourne Hospital, Melbourne, VIC, Australia", 
                "Department of Psychiatry, The University of Melbourne, Melbourne, VIC, Australia"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Rego", 
            "givenName": "Thomas", 
            "id": "sg:person.016220044217.83", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016220044217.83"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Royal Melbourne Hospital", 
              "id": "https://www.grid.ac/institutes/grid.416153.4", 
              "name": [
                "Neuropsychiatry Unit, The Royal Melbourne Hospital, Melbourne, VIC, Australia"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Farrand", 
            "givenName": "Sarah", 
            "id": "sg:person.014732154503.21", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014732154503.21"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "National Ageing Research Institute", 
              "id": "https://www.grid.ac/institutes/grid.429568.4", 
              "name": [
                "Neuropsychiatry Unit, The Royal Melbourne Hospital, Melbourne, VIC, Australia", 
                "Department of Psychiatry, The University of Melbourne, Melbourne, VIC, Australia", 
                "National Ageing Research Institute, Melbourne, VIC, Australia"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Goh", 
            "givenName": "Anita M. Y.", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Melbourne Health", 
              "id": "https://www.grid.ac/institutes/grid.429299.d", 
              "name": [
                "Neuropsychiatry Unit, The Royal Melbourne Hospital, Melbourne, VIC, Australia", 
                "Department of Psychiatry, The University of Melbourne, Melbourne, VIC, Australia", 
                "Melbourne Neuropsychiatry Centre, University of Melbourne and Melbourne Health, Melbourne, VIC, Australia"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Eratne", 
            "givenName": "Dhamidhu", 
            "id": "sg:person.010260657672.56", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010260657672.56"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Royal Melbourne Hospital", 
              "id": "https://www.grid.ac/institutes/grid.416153.4", 
              "name": [
                "Neuropsychiatry Unit, The Royal Melbourne Hospital, Melbourne, VIC, Australia"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Kelso", 
            "givenName": "Wendy", 
            "id": "sg:person.01365370434.61", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01365370434.61"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Monash Health", 
              "id": "https://www.grid.ac/institutes/grid.419789.a", 
              "name": [
                "Neuropsychiatry Unit, The Royal Melbourne Hospital, Melbourne, VIC, Australia", 
                "Movement Disorders Clinic, Kingston Centre, Monash Health, Cheltenham, VIC, Australia"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Mangelsdorf", 
            "givenName": "Simone", 
            "id": "sg:person.016325115503.17", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016325115503.17"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Melbourne Health", 
              "id": "https://www.grid.ac/institutes/grid.429299.d", 
              "name": [
                "Neuropsychiatry Unit, The Royal Melbourne Hospital, Melbourne, VIC, Australia", 
                "Department of Psychiatry, The University of Melbourne, Melbourne, VIC, Australia", 
                "Melbourne Neuropsychiatry Centre, University of Melbourne and Melbourne Health, Melbourne, VIC, Australia"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Velakoulis", 
            "givenName": "Dennis", 
            "id": "sg:person.01057416603.38", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01057416603.38"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Florey Institute of Neuroscience and Mental Health", 
              "id": "https://www.grid.ac/institutes/grid.418025.a", 
              "name": [
                "Neuropsychiatry Unit, The Royal Melbourne Hospital, Melbourne, VIC, Australia", 
                "Department of Psychiatry, The University of Melbourne, Melbourne, VIC, Australia", 
                "Melbourne Neuropsychiatry Centre, University of Melbourne and Melbourne Health, Melbourne, VIC, Australia", 
                "Florey Institute of Neuroscience and Mental Health, Melbourne, VIC, Australia"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Walterfang", 
            "givenName": "Mark", 
            "id": "sg:person.01057637507.24", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01057637507.24"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "https://doi.org/10.1098/rstb.2000.0734", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000408105"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ejpn.2013.08.002", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000495295"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3389/fnbeh.2014.00393", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001258651"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.neuroscience.2010.02.033", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002124561"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1001/archpsyc.63.2.139", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003707565"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/hipo.20741", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004028004"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1750-1172-9-65", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004064849", 
              "https://doi.org/10.1186/1750-1172-9-65"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s40478-016-0325-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004071962", 
              "https://doi.org/10.1186/s40478-016-0325-4"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1192/apt.6.3.161", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004192359"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ymgme.2009.12.006", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004339200"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10545-008-0923-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005240517", 
              "https://doi.org/10.1007/s10545-008-0923-9"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3174/ajnr.a3356", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005616940"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1750-1172-5-16", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005623887", 
              "https://doi.org/10.1186/1750-1172-5-16"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1750-1172-8-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005649083", 
              "https://doi.org/10.1186/1750-1172-8-1"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrneurol.2012.263", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005735277", 
              "https://doi.org/10.1038/nrneurol.2012.263"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/0891988713490992", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005905896"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/0891988713490992", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005905896"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0306-4522(01)00517-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006273125"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1006/nbdi.2002.0551", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006567192"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1006/nbdi.2002.0551", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006567192"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10545-012-9479-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006601850", 
              "https://doi.org/10.1007/s10545-012-9479-9"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1136/jnnp.74.4.528", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006640927"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ymgme.2016.06.004", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007294971"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.neubiorev.2015.01.013", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007366619"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.0402680101", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008422748"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ymgme.2009.06.008", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009639965"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/gim.2015.25", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009690156", 
              "https://doi.org/10.1038/gim.2015.25"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pgen.1003462", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009838002"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00318566", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010142660", 
              "https://doi.org/10.1007/bf00318566"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00318566", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010142660", 
              "https://doi.org/10.1007/bf00318566"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ymgme.2009.07.003", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011314186"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.encep.2015.11.003", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011749481"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1753-2000-8-20", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011764882", 
              "https://doi.org/10.1186/1753-2000-8-20"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1753-2000-8-20", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011764882", 
              "https://doi.org/10.1186/1753-2000-8-20"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrn1953", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011915611", 
              "https://doi.org/10.1038/nrn1953"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrn1953", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011915611", 
              "https://doi.org/10.1038/nrn1953"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/scitranslmed.3010101", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012551405"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1750-1172-8-12", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013643784", 
              "https://doi.org/10.1186/1750-1172-8-12"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s13023-014-0140-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014419105", 
              "https://doi.org/10.1186/s13023-014-0140-6"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s13023-014-0140-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014419105", 
              "https://doi.org/10.1186/s13023-014-0140-6"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00787-009-0010-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014562227", 
              "https://doi.org/10.1007/s00787-009-0010-2"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00787-009-0010-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014562227", 
              "https://doi.org/10.1007/s00787-009-0010-2"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00787-009-0010-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014562227", 
              "https://doi.org/10.1007/s00787-009-0010-2"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.schres.2014.09.034", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015070478"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/schbul/4.4.636", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015558231"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/glia.22665", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016844818"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.neuron.2013.10.044", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017161088"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s13023-015-0240-y", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017195893", 
              "https://doi.org/10.1186/s13023-015-0240-y"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s13023-015-0240-y", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017195893", 
              "https://doi.org/10.1186/s13023-015-0240-y"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10545-006-0417-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017657360", 
              "https://doi.org/10.1007/s10545-006-0417-6"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s12883-015-0511-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017880510", 
              "https://doi.org/10.1186/s12883-015-0511-1"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1001/archpsyc.57.11.1033", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018494705"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1023/a:1021259403196", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018560755", 
              "https://doi.org/10.1023/a:1021259403196"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/jnen/63.6.660", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019053843"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.concog.2016.02.005", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019067841"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s007020200073", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019105983", 
              "https://doi.org/10.1007/s007020200073"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00415-015-7819-z", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021043015", 
              "https://doi.org/10.1007/s00415-015-7819-z"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.mcn.2014.06.003", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021062259"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/brain/awh035", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021130268"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00227765", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021376406", 
              "https://doi.org/10.1007/bf00227765"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00227765", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021376406", 
              "https://doi.org/10.1007/bf00227765"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.pediatrneurol.2014.07.028", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021565195"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1080/14734220601169707", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021697120", 
              "https://doi.org/10.1080/14734220601169707"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10545-009-9958-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021799935", 
              "https://doi.org/10.1007/s10545-009-9958-9"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10545-009-9958-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021799935", 
              "https://doi.org/10.1007/s10545-009-9958-9"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s1474-4422(07)70194-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021955671"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/jnen/60.1.49", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021971309"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ymgme.2012.11.009", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022284482"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s13023-015-0377-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022621804", 
              "https://doi.org/10.1186/s13023-015-0377-8"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0022-510x(91)90208-o", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022861051"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0022-510x(91)90208-o", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022861051"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1023/a:1010942521671", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023033081", 
              "https://doi.org/10.1023/a:1010942521671"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10545-014-9794-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024135245", 
              "https://doi.org/10.1007/s10545-014-9794-4"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1001/archneur.1991.00530230086029", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024534482"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jns.2013.07.2434", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024636367"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/schbul/sbq105", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024710792"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1083/jcb.201407122", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025837712"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.biopsych.2010.08.022", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025983222"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3389/fnins.2015.00177", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1026485821"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3390/diseases4030029", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1026540870"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/brain/121.4.561", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1026910492"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ymgme.2012.03.012", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027225530"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nn1008", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027517528", 
              "https://doi.org/10.1038/nn1008"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nn1008", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027517528", 
              "https://doi.org/10.1038/nn1008"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.encep.2014.08.007", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027547472"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.nbd.2011.12.027", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028077223"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0920-9964(00)00028-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028723164"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/hmg/ddm100", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028741317"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1039/c3mt00308f", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028853123"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.nbd.2014.03.001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029333028"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10545-009-1173-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029456353", 
              "https://doi.org/10.1007/s10545-009-1173-1"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1155/2016/3830424", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030323750"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1471-4159.2008.05657.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030364055"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3389/fnsys.2015.00039", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030865365"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s13023-016-0502-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032637140", 
              "https://doi.org/10.1186/s13023-016-0502-3"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s13023-016-0502-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032637140", 
              "https://doi.org/10.1186/s13023-016-0502-3"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.schres.2016.07.014", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035043227"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.eurpsy.2007.02.006", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037546036"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00309338", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037789411", 
              "https://doi.org/10.1007/bf00309338"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00309338", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037789411", 
              "https://doi.org/10.1007/bf00309338"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10545-013-9618-y", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037853603", 
              "https://doi.org/10.1007/s10545-013-9618-y"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/ajmg.a.35395", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038154387"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.neulet.2011.03.097", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038171674"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1523/jneurosci.5981-10.2011", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038491996"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s12888-015-0578-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038690000", 
              "https://doi.org/10.1186/s12888-015-0578-7"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1001/archneur.1992.00530280095028", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038853967"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/mds.870100304", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038859053"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.4324/9781315785011", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039597806"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.nbd.2014.05.033", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039785101"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1469-8749.1998.tb15374.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040699414"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1469-8749.1998.tb15374.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040699414"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.eurpsy.2016.01.1698", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041086983"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.eurpsy.2016.01.1698", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041086983"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.eurpsy.2016.01.1698", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041086983"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10545-009-9021-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041419908", 
              "https://doi.org/10.1007/s10545-009-9021-x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/path.1345", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041594591"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/nen.0000000000000045", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041867131"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.encep.2013.04.013", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041964570"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pone.0001049", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042196054"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrn2536", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042265458", 
              "https://doi.org/10.1038/nrn2536"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.neubiorev.2008.09.002", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042321270"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0022-510x(05)80295-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043197479"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0387-7604(01)00252-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043489527"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1001/jama.1996.03540070057031", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043600999"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/jnc.13138", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043717834"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10545-007-0661-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044326634", 
              "https://doi.org/10.1007/s10545-007-0661-4"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1440-1614.2005.01678.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044568580"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.brainres.2011.04.020", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044902591"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1586/ern.11.135", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045592968"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/(sici)1097-4547(19970801)49:3<389::aid-jnr14>3.0.co;2-v", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046249120"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0042-6989(96)00066-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046292838"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.1303346110", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046538513"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.neuron.2010.02.014", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046952802"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/cne.1149", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047009138"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1001/archpsyc.62.6.593", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047074916"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.expneurol.2008.04.019", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047462755"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1001/jamapsychiatry.2013.1328", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047797358"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0387-7604(01)00209-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047871344"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1468-1331.2011.03545.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048004560"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.neubiorev.2009.12.009", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048604076"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1440-1614.2006.01923.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049525771"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.neubiorev.2006.02.001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049601327"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1192/bjp.bp.108.057034", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050244785"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1001/archneur.1997.00550240084016", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050500655"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.pediatrneurol.2005.05.004", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050727689"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrn2457", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051119996", 
              "https://doi.org/10.1038/nrn2457"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2217/clp.12.31", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052114177"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.schres.2012.06.032", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052157932"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1523/jneurosci.1868-09.2009", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052175671"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10545-007-0630-y", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052560957", 
              "https://doi.org/10.1007/s10545-007-0630-y"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/brain/awl260", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052588466"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0014-4886(03)00345-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053067760"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0014-4886(03)00345-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053067760"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0074-7742(08)60346-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053342105"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/brain/awu132", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053727728"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1017/s0033291713000263", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053902670"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/brain/118.1.119", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1059439416"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/schbul/sbw100", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1060024125"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1101/mcs.a001222", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1060407680"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.283.5409.1908", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1062564566"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1176/appi.ajp.162.5.1021-a", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1063496620"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1176/appi.ajp.2010.09081187", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1063498911"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1176/appi.ajp.2013.13070981", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1063500115"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1176/jnp.10.1.10", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1063511468"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1176/jnp.15.3.289", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1063511980"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1176/jnp.2006.18.2.158", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1063512344"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1212/01.wnl.0000345040.01917.9d", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064351055"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1212/01.wnl.0000345040.01917.9d", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064351055"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1212/01.wnl.0000345040.01917.9d", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064351055"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1212/wnl.0b013e3181e6210e", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064355370"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1212/wnl.0b013e3181e6210e", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064355370"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1212/wnl.0b013e3181e6210e", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064355370"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1212/wnl.0b013e3182563b82", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064356925"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1212/wnl.0b013e3182563b82", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064356925"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1212/wnl.0b013e3182563b82", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064356925"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1212/wnl.45.9.1739", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064373540"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1212/wnl.45.9.1739", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064373540"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1212/wnl.45.9.1739", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064373540"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2147/nedt.2006.2.4.531", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1069103305"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1079295907", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1082423652", 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s13023-017-0579-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1083403203", 
              "https://doi.org/10.1186/s13023-017-0579-3"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s13023-017-0579-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1083403203", 
              "https://doi.org/10.1186/s13023-017-0579-3"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10072-017-2833-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1083424613", 
              "https://doi.org/10.1007/s10072-017-2833-9"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10072-017-2833-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1083424613", 
              "https://doi.org/10.1007/s10072-017-2833-9"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1080/03007995.2017.1294054", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1083777828"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1192/pb.bp.116.054072", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1084737802"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1080/02643294.2017.1340264", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1090391568"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1080/02643294.2017.1340264", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1090391568"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/8904_2017_42", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1090659534", 
              "https://doi.org/10.1007/8904_2017_42"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0140-6736(17)31465-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1091146813"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1080/15622975.2017.1379610", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1091787586"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s13023-017-0714-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1092273615", 
              "https://doi.org/10.1186/s13023-017-0714-1"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/s41593-017-0020-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1092621925", 
              "https://doi.org/10.1038/s41593-017-0020-1"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.biopsych.2017.11.008", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1092728036"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.biopsych.2017.11.008", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1092728036"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3389/fnmol.2017.00382", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1092743987"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.pediatrneurol.2017.12.014", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1100248593"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.pediatrneurol.2017.12.014", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1100248593"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/mp.2017.249", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1100269066", 
              "https://doi.org/10.1038/mp.2017.249"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/mp.2017.249", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1100269066", 
              "https://doi.org/10.1038/mp.2017.249"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/mp.2017.249", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1100269066", 
              "https://doi.org/10.1038/mp.2017.249"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/mp.2017.249", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1100269066", 
              "https://doi.org/10.1038/mp.2017.249"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.12688/f1000research.12361.1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1101066894"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.12688/f1000research.12361.1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1101066894"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1080/15622975.2018.1441548", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1101114427"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s13023-018-0833-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1104405286", 
              "https://doi.org/10.1186/s13023-018-0833-3"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s13023-018-0833-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1104405286", 
              "https://doi.org/10.1186/s13023-018-0833-3"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1017/s1092852918001013", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1105212416"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1017/s1092852918001013", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1105212416"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s13023-018-0844-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1106151479", 
              "https://doi.org/10.1186/s13023-018-0844-0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s13023-018-0844-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1106151479", 
              "https://doi.org/10.1186/s13023-018-0844-0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s13023-018-0844-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1106151479", 
              "https://doi.org/10.1186/s13023-018-0844-0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s12883-018-1124-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1106156018", 
              "https://doi.org/10.1186/s12883-018-1124-2"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1017/cbo9781139003872", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1108553816"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2019-02", 
        "datePublishedReg": "2019-02-01", 
        "description": "Niemann-Pick disease type C (NPC) is a lysosomal storage disorder that presents with a spectrum of clinical manifestations from infancy and childhood or in early or mid-adulthood. Progressive neurological symptoms including ataxia, dystonia and vertical gaze palsy are a hallmark of the disease, and psychiatric symptoms such as psychosis and mood disorders are common. These latter symptoms often present early in the course of NPC and thus these patients are often diagnosed with a major psychotic or affective disorder before neurological and cognitive signs present and the diagnosis is revised. The commonalities and characteristics of psychotic symptoms in both NPC and schizophrenia may share neuronal pathways and mechanisms and provide potential targets for research in both disorders. The neurobiology of NPC and its relationship to the pattern of neuropsychiatric and cognitive symptoms is described in this review. A number of neurobiological models are proposed as mechanisms by which NPC causes psychiatric and cognitive symptoms, informed from models proposed in schizophrenia and other metabolic disorders. There are a number of symptomatic and illness-modifying treatments for NPC currently available. The current evidence is discussed; focussing on two medications which have shown promise, miglustat and hydroxypropyl-\u03b2-cyclodextrin.", 
        "genre": "research_article", 
        "id": "sg:pub.10.1007/s40263-018-0599-0", 
        "inLanguage": [
          "en"
        ], 
        "isAccessibleForFree": false, 
        "isPartOf": [
          {
            "id": "sg:journal.1111875", 
            "issn": [
              "1172-7047", 
              "1179-1934"
            ], 
            "name": "CNS Drugs", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "2", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "33"
          }
        ], 
        "name": "Psychiatric and Cognitive Symptoms Associated with Niemann-Pick Type C Disease: Neurobiology and Management", 
        "pagination": "125-142", 
        "productId": [
          {
            "name": "readcube_id", 
            "type": "PropertyValue", 
            "value": [
              "08281ea87163a562fdba4420288cefd6c6f4d5a15fcdb5dcb26d2f45cf5a8d62"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "30632019"
            ]
          }, 
          {
            "name": "nlm_unique_id", 
            "type": "PropertyValue", 
            "value": [
              "9431220"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1007/s40263-018-0599-0"
            ]
          }, 
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1111314817"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1007/s40263-018-0599-0", 
          "https://app.dimensions.ai/details/publication/pub.1111314817"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2019-04-11T11:14", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000353_0000000353/records_45376_00000002.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "https://link.springer.com/10.1007%2Fs40263-018-0599-0"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s40263-018-0599-0'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s40263-018-0599-0'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s40263-018-0599-0'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s40263-018-0599-0'


     

    This table displays all metadata directly associated to this object as RDF triples.

    710 TRIPLES      21 PREDICATES      204 URIs      21 LITERALS      9 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1007/s40263-018-0599-0 schema:about anzsrc-for:11
    2 anzsrc-for:1103
    3 schema:author N1f8b9e5cc58b4ece9d8b2c05548b5b31
    4 schema:citation sg:pub.10.1007/8904_2017_42
    5 sg:pub.10.1007/bf00227765
    6 sg:pub.10.1007/bf00309338
    7 sg:pub.10.1007/bf00318566
    8 sg:pub.10.1007/s00415-015-7819-z
    9 sg:pub.10.1007/s007020200073
    10 sg:pub.10.1007/s00787-009-0010-2
    11 sg:pub.10.1007/s10072-017-2833-9
    12 sg:pub.10.1007/s10545-006-0417-6
    13 sg:pub.10.1007/s10545-007-0630-y
    14 sg:pub.10.1007/s10545-007-0661-4
    15 sg:pub.10.1007/s10545-008-0923-9
    16 sg:pub.10.1007/s10545-009-1173-1
    17 sg:pub.10.1007/s10545-009-9021-x
    18 sg:pub.10.1007/s10545-009-9958-9
    19 sg:pub.10.1007/s10545-012-9479-9
    20 sg:pub.10.1007/s10545-013-9618-y
    21 sg:pub.10.1007/s10545-014-9794-4
    22 sg:pub.10.1023/a:1010942521671
    23 sg:pub.10.1023/a:1021259403196
    24 sg:pub.10.1038/gim.2015.25
    25 sg:pub.10.1038/mp.2017.249
    26 sg:pub.10.1038/nn1008
    27 sg:pub.10.1038/nrn1953
    28 sg:pub.10.1038/nrn2457
    29 sg:pub.10.1038/nrn2536
    30 sg:pub.10.1038/nrneurol.2012.263
    31 sg:pub.10.1038/s41593-017-0020-1
    32 sg:pub.10.1080/14734220601169707
    33 sg:pub.10.1186/1750-1172-5-16
    34 sg:pub.10.1186/1750-1172-8-1
    35 sg:pub.10.1186/1750-1172-8-12
    36 sg:pub.10.1186/1750-1172-9-65
    37 sg:pub.10.1186/1753-2000-8-20
    38 sg:pub.10.1186/s12883-015-0511-1
    39 sg:pub.10.1186/s12883-018-1124-2
    40 sg:pub.10.1186/s12888-015-0578-7
    41 sg:pub.10.1186/s13023-014-0140-6
    42 sg:pub.10.1186/s13023-015-0240-y
    43 sg:pub.10.1186/s13023-015-0377-8
    44 sg:pub.10.1186/s13023-016-0502-3
    45 sg:pub.10.1186/s13023-017-0579-3
    46 sg:pub.10.1186/s13023-017-0714-1
    47 sg:pub.10.1186/s13023-018-0833-3
    48 sg:pub.10.1186/s13023-018-0844-0
    49 sg:pub.10.1186/s40478-016-0325-4
    50 https://app.dimensions.ai/details/publication/pub.1079295907
    51 https://app.dimensions.ai/details/publication/pub.1082423652
    52 https://doi.org/10.1001/archneur.1991.00530230086029
    53 https://doi.org/10.1001/archneur.1992.00530280095028
    54 https://doi.org/10.1001/archneur.1997.00550240084016
    55 https://doi.org/10.1001/archpsyc.57.11.1033
    56 https://doi.org/10.1001/archpsyc.62.6.593
    57 https://doi.org/10.1001/archpsyc.63.2.139
    58 https://doi.org/10.1001/jama.1996.03540070057031
    59 https://doi.org/10.1001/jamapsychiatry.2013.1328
    60 https://doi.org/10.1002/(sici)1097-4547(19970801)49:3<389::aid-jnr14>3.0.co;2-v
    61 https://doi.org/10.1002/ajmg.a.35395
    62 https://doi.org/10.1002/cne.1149
    63 https://doi.org/10.1002/glia.22665
    64 https://doi.org/10.1002/hipo.20741
    65 https://doi.org/10.1002/mds.870100304
    66 https://doi.org/10.1002/path.1345
    67 https://doi.org/10.1006/nbdi.2002.0551
    68 https://doi.org/10.1016/0022-510x(91)90208-o
    69 https://doi.org/10.1016/j.biopsych.2010.08.022
    70 https://doi.org/10.1016/j.biopsych.2017.11.008
    71 https://doi.org/10.1016/j.brainres.2011.04.020
    72 https://doi.org/10.1016/j.concog.2016.02.005
    73 https://doi.org/10.1016/j.ejpn.2013.08.002
    74 https://doi.org/10.1016/j.encep.2013.04.013
    75 https://doi.org/10.1016/j.encep.2014.08.007
    76 https://doi.org/10.1016/j.encep.2015.11.003
    77 https://doi.org/10.1016/j.eurpsy.2007.02.006
    78 https://doi.org/10.1016/j.eurpsy.2016.01.1698
    79 https://doi.org/10.1016/j.expneurol.2008.04.019
    80 https://doi.org/10.1016/j.jns.2013.07.2434
    81 https://doi.org/10.1016/j.mcn.2014.06.003
    82 https://doi.org/10.1016/j.nbd.2011.12.027
    83 https://doi.org/10.1016/j.nbd.2014.03.001
    84 https://doi.org/10.1016/j.nbd.2014.05.033
    85 https://doi.org/10.1016/j.neubiorev.2006.02.001
    86 https://doi.org/10.1016/j.neubiorev.2008.09.002
    87 https://doi.org/10.1016/j.neubiorev.2009.12.009
    88 https://doi.org/10.1016/j.neubiorev.2015.01.013
    89 https://doi.org/10.1016/j.neulet.2011.03.097
    90 https://doi.org/10.1016/j.neuron.2010.02.014
    91 https://doi.org/10.1016/j.neuron.2013.10.044
    92 https://doi.org/10.1016/j.neuroscience.2010.02.033
    93 https://doi.org/10.1016/j.pediatrneurol.2005.05.004
    94 https://doi.org/10.1016/j.pediatrneurol.2014.07.028
    95 https://doi.org/10.1016/j.pediatrneurol.2017.12.014
    96 https://doi.org/10.1016/j.schres.2012.06.032
    97 https://doi.org/10.1016/j.schres.2014.09.034
    98 https://doi.org/10.1016/j.schres.2016.07.014
    99 https://doi.org/10.1016/j.ymgme.2009.06.008
    100 https://doi.org/10.1016/j.ymgme.2009.07.003
    101 https://doi.org/10.1016/j.ymgme.2009.12.006
    102 https://doi.org/10.1016/j.ymgme.2012.03.012
    103 https://doi.org/10.1016/j.ymgme.2012.11.009
    104 https://doi.org/10.1016/j.ymgme.2016.06.004
    105 https://doi.org/10.1016/s0014-4886(03)00345-5
    106 https://doi.org/10.1016/s0022-510x(05)80295-3
    107 https://doi.org/10.1016/s0042-6989(96)00066-1
    108 https://doi.org/10.1016/s0074-7742(08)60346-3
    109 https://doi.org/10.1016/s0140-6736(17)31465-4
    110 https://doi.org/10.1016/s0306-4522(01)00517-6
    111 https://doi.org/10.1016/s0387-7604(01)00209-1
    112 https://doi.org/10.1016/s0387-7604(01)00252-2
    113 https://doi.org/10.1016/s0920-9964(00)00028-1
    114 https://doi.org/10.1016/s1474-4422(07)70194-1
    115 https://doi.org/10.1017/cbo9781139003872
    116 https://doi.org/10.1017/s0033291713000263
    117 https://doi.org/10.1017/s1092852918001013
    118 https://doi.org/10.1039/c3mt00308f
    119 https://doi.org/10.1073/pnas.0402680101
    120 https://doi.org/10.1073/pnas.1303346110
    121 https://doi.org/10.1080/02643294.2017.1340264
    122 https://doi.org/10.1080/03007995.2017.1294054
    123 https://doi.org/10.1080/15622975.2017.1379610
    124 https://doi.org/10.1080/15622975.2018.1441548
    125 https://doi.org/10.1083/jcb.201407122
    126 https://doi.org/10.1093/brain/118.1.119
    127 https://doi.org/10.1093/brain/121.4.561
    128 https://doi.org/10.1093/brain/awh035
    129 https://doi.org/10.1093/brain/awl260
    130 https://doi.org/10.1093/brain/awu132
    131 https://doi.org/10.1093/hmg/ddm100
    132 https://doi.org/10.1093/jnen/60.1.49
    133 https://doi.org/10.1093/jnen/63.6.660
    134 https://doi.org/10.1093/schbul/4.4.636
    135 https://doi.org/10.1093/schbul/sbq105
    136 https://doi.org/10.1093/schbul/sbw100
    137 https://doi.org/10.1097/nen.0000000000000045
    138 https://doi.org/10.1098/rstb.2000.0734
    139 https://doi.org/10.1101/mcs.a001222
    140 https://doi.org/10.1111/j.1440-1614.2005.01678.x
    141 https://doi.org/10.1111/j.1440-1614.2006.01923.x
    142 https://doi.org/10.1111/j.1468-1331.2011.03545.x
    143 https://doi.org/10.1111/j.1469-8749.1998.tb15374.x
    144 https://doi.org/10.1111/j.1471-4159.2008.05657.x
    145 https://doi.org/10.1111/jnc.13138
    146 https://doi.org/10.1126/science.283.5409.1908
    147 https://doi.org/10.1126/scitranslmed.3010101
    148 https://doi.org/10.1136/jnnp.74.4.528
    149 https://doi.org/10.1155/2016/3830424
    150 https://doi.org/10.1176/appi.ajp.162.5.1021-a
    151 https://doi.org/10.1176/appi.ajp.2010.09081187
    152 https://doi.org/10.1176/appi.ajp.2013.13070981
    153 https://doi.org/10.1176/jnp.10.1.10
    154 https://doi.org/10.1176/jnp.15.3.289
    155 https://doi.org/10.1176/jnp.2006.18.2.158
    156 https://doi.org/10.1177/0891988713490992
    157 https://doi.org/10.1192/apt.6.3.161
    158 https://doi.org/10.1192/bjp.bp.108.057034
    159 https://doi.org/10.1192/pb.bp.116.054072
    160 https://doi.org/10.1212/01.wnl.0000345040.01917.9d
    161 https://doi.org/10.1212/wnl.0b013e3181e6210e
    162 https://doi.org/10.1212/wnl.0b013e3182563b82
    163 https://doi.org/10.1212/wnl.45.9.1739
    164 https://doi.org/10.12688/f1000research.12361.1
    165 https://doi.org/10.1371/journal.pgen.1003462
    166 https://doi.org/10.1371/journal.pone.0001049
    167 https://doi.org/10.1523/jneurosci.1868-09.2009
    168 https://doi.org/10.1523/jneurosci.5981-10.2011
    169 https://doi.org/10.1586/ern.11.135
    170 https://doi.org/10.2147/nedt.2006.2.4.531
    171 https://doi.org/10.2217/clp.12.31
    172 https://doi.org/10.3174/ajnr.a3356
    173 https://doi.org/10.3389/fnbeh.2014.00393
    174 https://doi.org/10.3389/fnins.2015.00177
    175 https://doi.org/10.3389/fnmol.2017.00382
    176 https://doi.org/10.3389/fnsys.2015.00039
    177 https://doi.org/10.3390/diseases4030029
    178 https://doi.org/10.4324/9781315785011
    179 schema:datePublished 2019-02
    180 schema:datePublishedReg 2019-02-01
    181 schema:description Niemann-Pick disease type C (NPC) is a lysosomal storage disorder that presents with a spectrum of clinical manifestations from infancy and childhood or in early or mid-adulthood. Progressive neurological symptoms including ataxia, dystonia and vertical gaze palsy are a hallmark of the disease, and psychiatric symptoms such as psychosis and mood disorders are common. These latter symptoms often present early in the course of NPC and thus these patients are often diagnosed with a major psychotic or affective disorder before neurological and cognitive signs present and the diagnosis is revised. The commonalities and characteristics of psychotic symptoms in both NPC and schizophrenia may share neuronal pathways and mechanisms and provide potential targets for research in both disorders. The neurobiology of NPC and its relationship to the pattern of neuropsychiatric and cognitive symptoms is described in this review. A number of neurobiological models are proposed as mechanisms by which NPC causes psychiatric and cognitive symptoms, informed from models proposed in schizophrenia and other metabolic disorders. There are a number of symptomatic and illness-modifying treatments for NPC currently available. The current evidence is discussed; focussing on two medications which have shown promise, miglustat and hydroxypropyl-β-cyclodextrin.
    182 schema:genre research_article
    183 schema:inLanguage en
    184 schema:isAccessibleForFree false
    185 schema:isPartOf N5d7cfbeded8743a8a75452f10cfc333c
    186 Nce26667a444b42bea2b7dcb48fd57c33
    187 sg:journal.1111875
    188 schema:name Psychiatric and Cognitive Symptoms Associated with Niemann-Pick Type C Disease: Neurobiology and Management
    189 schema:pagination 125-142
    190 schema:productId N37a62c8155c8404fb07235fc9eb2ac4f
    191 N44c2cb64e29e4f0ca52f6774982c3ed5
    192 N6ccd928993454859b3ff187da0a50c29
    193 N79ea2f75418841a2833fb72e9ad2d671
    194 Ne752e4b25d10469186269124eed34fb6
    195 schema:sameAs https://app.dimensions.ai/details/publication/pub.1111314817
    196 https://doi.org/10.1007/s40263-018-0599-0
    197 schema:sdDatePublished 2019-04-11T11:14
    198 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    199 schema:sdPublisher N058e111560c04dd399bf3d382273403c
    200 schema:url https://link.springer.com/10.1007%2Fs40263-018-0599-0
    201 sgo:license sg:explorer/license/
    202 sgo:sdDataset articles
    203 rdf:type schema:ScholarlyArticle
    204 N058e111560c04dd399bf3d382273403c schema:name Springer Nature - SN SciGraph project
    205 rdf:type schema:Organization
    206 N0df542fb3fee45ffaeb4e27a75f2b233 rdf:first sg:person.01057637507.24
    207 rdf:rest rdf:nil
    208 N1f8b9e5cc58b4ece9d8b2c05548b5b31 rdf:first sg:person.016220044217.83
    209 rdf:rest N41d6abf9b9e541a9b90980a5c3f9b46f
    210 N348e537594b84ae5906aa6d384caf0da schema:affiliation https://www.grid.ac/institutes/grid.429568.4
    211 schema:familyName Goh
    212 schema:givenName Anita M. Y.
    213 rdf:type schema:Person
    214 N37a62c8155c8404fb07235fc9eb2ac4f schema:name readcube_id
    215 schema:value 08281ea87163a562fdba4420288cefd6c6f4d5a15fcdb5dcb26d2f45cf5a8d62
    216 rdf:type schema:PropertyValue
    217 N41d6abf9b9e541a9b90980a5c3f9b46f rdf:first sg:person.014732154503.21
    218 rdf:rest Nadd9dfa4743a4d21a2bed0cf94d2fca7
    219 N44c2cb64e29e4f0ca52f6774982c3ed5 schema:name pubmed_id
    220 schema:value 30632019
    221 rdf:type schema:PropertyValue
    222 N5d7cfbeded8743a8a75452f10cfc333c schema:issueNumber 2
    223 rdf:type schema:PublicationIssue
    224 N6ccd928993454859b3ff187da0a50c29 schema:name doi
    225 schema:value 10.1007/s40263-018-0599-0
    226 rdf:type schema:PropertyValue
    227 N79ea2f75418841a2833fb72e9ad2d671 schema:name nlm_unique_id
    228 schema:value 9431220
    229 rdf:type schema:PropertyValue
    230 N7ebd5a2992d247a4a98021eba891a3d5 rdf:first sg:person.016325115503.17
    231 rdf:rest Ncfc9a4cdd1b24cc3a7ffa18348614f4e
    232 Nadd9dfa4743a4d21a2bed0cf94d2fca7 rdf:first N348e537594b84ae5906aa6d384caf0da
    233 rdf:rest Ncf3310742c594b8581f9b3ecf9d378dc
    234 Nce26667a444b42bea2b7dcb48fd57c33 schema:volumeNumber 33
    235 rdf:type schema:PublicationVolume
    236 Ncf3310742c594b8581f9b3ecf9d378dc rdf:first sg:person.010260657672.56
    237 rdf:rest Nf0d1b69205db4c7ea22bdfda0b882fd0
    238 Ncfc9a4cdd1b24cc3a7ffa18348614f4e rdf:first sg:person.01057416603.38
    239 rdf:rest N0df542fb3fee45ffaeb4e27a75f2b233
    240 Ne752e4b25d10469186269124eed34fb6 schema:name dimensions_id
    241 schema:value pub.1111314817
    242 rdf:type schema:PropertyValue
    243 Nf0d1b69205db4c7ea22bdfda0b882fd0 rdf:first sg:person.01365370434.61
    244 rdf:rest N7ebd5a2992d247a4a98021eba891a3d5
    245 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
    246 schema:name Medical and Health Sciences
    247 rdf:type schema:DefinedTerm
    248 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
    249 schema:name Clinical Sciences
    250 rdf:type schema:DefinedTerm
    251 sg:journal.1111875 schema:issn 1172-7047
    252 1179-1934
    253 schema:name CNS Drugs
    254 rdf:type schema:Periodical
    255 sg:person.010260657672.56 schema:affiliation https://www.grid.ac/institutes/grid.429299.d
    256 schema:familyName Eratne
    257 schema:givenName Dhamidhu
    258 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010260657672.56
    259 rdf:type schema:Person
    260 sg:person.01057416603.38 schema:affiliation https://www.grid.ac/institutes/grid.429299.d
    261 schema:familyName Velakoulis
    262 schema:givenName Dennis
    263 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01057416603.38
    264 rdf:type schema:Person
    265 sg:person.01057637507.24 schema:affiliation https://www.grid.ac/institutes/grid.418025.a
    266 schema:familyName Walterfang
    267 schema:givenName Mark
    268 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01057637507.24
    269 rdf:type schema:Person
    270 sg:person.01365370434.61 schema:affiliation https://www.grid.ac/institutes/grid.416153.4
    271 schema:familyName Kelso
    272 schema:givenName Wendy
    273 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01365370434.61
    274 rdf:type schema:Person
    275 sg:person.014732154503.21 schema:affiliation https://www.grid.ac/institutes/grid.416153.4
    276 schema:familyName Farrand
    277 schema:givenName Sarah
    278 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014732154503.21
    279 rdf:type schema:Person
    280 sg:person.016220044217.83 schema:affiliation https://www.grid.ac/institutes/grid.1008.9
    281 schema:familyName Rego
    282 schema:givenName Thomas
    283 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016220044217.83
    284 rdf:type schema:Person
    285 sg:person.016325115503.17 schema:affiliation https://www.grid.ac/institutes/grid.419789.a
    286 schema:familyName Mangelsdorf
    287 schema:givenName Simone
    288 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016325115503.17
    289 rdf:type schema:Person
    290 sg:pub.10.1007/8904_2017_42 schema:sameAs https://app.dimensions.ai/details/publication/pub.1090659534
    291 https://doi.org/10.1007/8904_2017_42
    292 rdf:type schema:CreativeWork
    293 sg:pub.10.1007/bf00227765 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021376406
    294 https://doi.org/10.1007/bf00227765
    295 rdf:type schema:CreativeWork
    296 sg:pub.10.1007/bf00309338 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037789411
    297 https://doi.org/10.1007/bf00309338
    298 rdf:type schema:CreativeWork
    299 sg:pub.10.1007/bf00318566 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010142660
    300 https://doi.org/10.1007/bf00318566
    301 rdf:type schema:CreativeWork
    302 sg:pub.10.1007/s00415-015-7819-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1021043015
    303 https://doi.org/10.1007/s00415-015-7819-z
    304 rdf:type schema:CreativeWork
    305 sg:pub.10.1007/s007020200073 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019105983
    306 https://doi.org/10.1007/s007020200073
    307 rdf:type schema:CreativeWork
    308 sg:pub.10.1007/s00787-009-0010-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014562227
    309 https://doi.org/10.1007/s00787-009-0010-2
    310 rdf:type schema:CreativeWork
    311 sg:pub.10.1007/s10072-017-2833-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083424613
    312 https://doi.org/10.1007/s10072-017-2833-9
    313 rdf:type schema:CreativeWork
    314 sg:pub.10.1007/s10545-006-0417-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017657360
    315 https://doi.org/10.1007/s10545-006-0417-6
    316 rdf:type schema:CreativeWork
    317 sg:pub.10.1007/s10545-007-0630-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1052560957
    318 https://doi.org/10.1007/s10545-007-0630-y
    319 rdf:type schema:CreativeWork
    320 sg:pub.10.1007/s10545-007-0661-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044326634
    321 https://doi.org/10.1007/s10545-007-0661-4
    322 rdf:type schema:CreativeWork
    323 sg:pub.10.1007/s10545-008-0923-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005240517
    324 https://doi.org/10.1007/s10545-008-0923-9
    325 rdf:type schema:CreativeWork
    326 sg:pub.10.1007/s10545-009-1173-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029456353
    327 https://doi.org/10.1007/s10545-009-1173-1
    328 rdf:type schema:CreativeWork
    329 sg:pub.10.1007/s10545-009-9021-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1041419908
    330 https://doi.org/10.1007/s10545-009-9021-x
    331 rdf:type schema:CreativeWork
    332 sg:pub.10.1007/s10545-009-9958-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021799935
    333 https://doi.org/10.1007/s10545-009-9958-9
    334 rdf:type schema:CreativeWork
    335 sg:pub.10.1007/s10545-012-9479-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006601850
    336 https://doi.org/10.1007/s10545-012-9479-9
    337 rdf:type schema:CreativeWork
    338 sg:pub.10.1007/s10545-013-9618-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1037853603
    339 https://doi.org/10.1007/s10545-013-9618-y
    340 rdf:type schema:CreativeWork
    341 sg:pub.10.1007/s10545-014-9794-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024135245
    342 https://doi.org/10.1007/s10545-014-9794-4
    343 rdf:type schema:CreativeWork
    344 sg:pub.10.1023/a:1010942521671 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023033081
    345 https://doi.org/10.1023/a:1010942521671
    346 rdf:type schema:CreativeWork
    347 sg:pub.10.1023/a:1021259403196 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018560755
    348 https://doi.org/10.1023/a:1021259403196
    349 rdf:type schema:CreativeWork
    350 sg:pub.10.1038/gim.2015.25 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009690156
    351 https://doi.org/10.1038/gim.2015.25
    352 rdf:type schema:CreativeWork
    353 sg:pub.10.1038/mp.2017.249 schema:sameAs https://app.dimensions.ai/details/publication/pub.1100269066
    354 https://doi.org/10.1038/mp.2017.249
    355 rdf:type schema:CreativeWork
    356 sg:pub.10.1038/nn1008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027517528
    357 https://doi.org/10.1038/nn1008
    358 rdf:type schema:CreativeWork
    359 sg:pub.10.1038/nrn1953 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011915611
    360 https://doi.org/10.1038/nrn1953
    361 rdf:type schema:CreativeWork
    362 sg:pub.10.1038/nrn2457 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051119996
    363 https://doi.org/10.1038/nrn2457
    364 rdf:type schema:CreativeWork
    365 sg:pub.10.1038/nrn2536 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042265458
    366 https://doi.org/10.1038/nrn2536
    367 rdf:type schema:CreativeWork
    368 sg:pub.10.1038/nrneurol.2012.263 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005735277
    369 https://doi.org/10.1038/nrneurol.2012.263
    370 rdf:type schema:CreativeWork
    371 sg:pub.10.1038/s41593-017-0020-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1092621925
    372 https://doi.org/10.1038/s41593-017-0020-1
    373 rdf:type schema:CreativeWork
    374 sg:pub.10.1080/14734220601169707 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021697120
    375 https://doi.org/10.1080/14734220601169707
    376 rdf:type schema:CreativeWork
    377 sg:pub.10.1186/1750-1172-5-16 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005623887
    378 https://doi.org/10.1186/1750-1172-5-16
    379 rdf:type schema:CreativeWork
    380 sg:pub.10.1186/1750-1172-8-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005649083
    381 https://doi.org/10.1186/1750-1172-8-1
    382 rdf:type schema:CreativeWork
    383 sg:pub.10.1186/1750-1172-8-12 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013643784
    384 https://doi.org/10.1186/1750-1172-8-12
    385 rdf:type schema:CreativeWork
    386 sg:pub.10.1186/1750-1172-9-65 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004064849
    387 https://doi.org/10.1186/1750-1172-9-65
    388 rdf:type schema:CreativeWork
    389 sg:pub.10.1186/1753-2000-8-20 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011764882
    390 https://doi.org/10.1186/1753-2000-8-20
    391 rdf:type schema:CreativeWork
    392 sg:pub.10.1186/s12883-015-0511-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017880510
    393 https://doi.org/10.1186/s12883-015-0511-1
    394 rdf:type schema:CreativeWork
    395 sg:pub.10.1186/s12883-018-1124-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1106156018
    396 https://doi.org/10.1186/s12883-018-1124-2
    397 rdf:type schema:CreativeWork
    398 sg:pub.10.1186/s12888-015-0578-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038690000
    399 https://doi.org/10.1186/s12888-015-0578-7
    400 rdf:type schema:CreativeWork
    401 sg:pub.10.1186/s13023-014-0140-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014419105
    402 https://doi.org/10.1186/s13023-014-0140-6
    403 rdf:type schema:CreativeWork
    404 sg:pub.10.1186/s13023-015-0240-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1017195893
    405 https://doi.org/10.1186/s13023-015-0240-y
    406 rdf:type schema:CreativeWork
    407 sg:pub.10.1186/s13023-015-0377-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022621804
    408 https://doi.org/10.1186/s13023-015-0377-8
    409 rdf:type schema:CreativeWork
    410 sg:pub.10.1186/s13023-016-0502-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032637140
    411 https://doi.org/10.1186/s13023-016-0502-3
    412 rdf:type schema:CreativeWork
    413 sg:pub.10.1186/s13023-017-0579-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083403203
    414 https://doi.org/10.1186/s13023-017-0579-3
    415 rdf:type schema:CreativeWork
    416 sg:pub.10.1186/s13023-017-0714-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1092273615
    417 https://doi.org/10.1186/s13023-017-0714-1
    418 rdf:type schema:CreativeWork
    419 sg:pub.10.1186/s13023-018-0833-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1104405286
    420 https://doi.org/10.1186/s13023-018-0833-3
    421 rdf:type schema:CreativeWork
    422 sg:pub.10.1186/s13023-018-0844-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1106151479
    423 https://doi.org/10.1186/s13023-018-0844-0
    424 rdf:type schema:CreativeWork
    425 sg:pub.10.1186/s40478-016-0325-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004071962
    426 https://doi.org/10.1186/s40478-016-0325-4
    427 rdf:type schema:CreativeWork
    428 https://app.dimensions.ai/details/publication/pub.1079295907 schema:CreativeWork
    429 https://app.dimensions.ai/details/publication/pub.1082423652 schema:CreativeWork
    430 https://doi.org/10.1001/archneur.1991.00530230086029 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024534482
    431 rdf:type schema:CreativeWork
    432 https://doi.org/10.1001/archneur.1992.00530280095028 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038853967
    433 rdf:type schema:CreativeWork
    434 https://doi.org/10.1001/archneur.1997.00550240084016 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050500655
    435 rdf:type schema:CreativeWork
    436 https://doi.org/10.1001/archpsyc.57.11.1033 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018494705
    437 rdf:type schema:CreativeWork
    438 https://doi.org/10.1001/archpsyc.62.6.593 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047074916
    439 rdf:type schema:CreativeWork
    440 https://doi.org/10.1001/archpsyc.63.2.139 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003707565
    441 rdf:type schema:CreativeWork
    442 https://doi.org/10.1001/jama.1996.03540070057031 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043600999
    443 rdf:type schema:CreativeWork
    444 https://doi.org/10.1001/jamapsychiatry.2013.1328 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047797358
    445 rdf:type schema:CreativeWork
    446 https://doi.org/10.1002/(sici)1097-4547(19970801)49:3<389::aid-jnr14>3.0.co;2-v schema:sameAs https://app.dimensions.ai/details/publication/pub.1046249120
    447 rdf:type schema:CreativeWork
    448 https://doi.org/10.1002/ajmg.a.35395 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038154387
    449 rdf:type schema:CreativeWork
    450 https://doi.org/10.1002/cne.1149 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047009138
    451 rdf:type schema:CreativeWork
    452 https://doi.org/10.1002/glia.22665 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016844818
    453 rdf:type schema:CreativeWork
    454 https://doi.org/10.1002/hipo.20741 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004028004
    455 rdf:type schema:CreativeWork
    456 https://doi.org/10.1002/mds.870100304 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038859053
    457 rdf:type schema:CreativeWork
    458 https://doi.org/10.1002/path.1345 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041594591
    459 rdf:type schema:CreativeWork
    460 https://doi.org/10.1006/nbdi.2002.0551 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006567192
    461 rdf:type schema:CreativeWork
    462 https://doi.org/10.1016/0022-510x(91)90208-o schema:sameAs https://app.dimensions.ai/details/publication/pub.1022861051
    463 rdf:type schema:CreativeWork
    464 https://doi.org/10.1016/j.biopsych.2010.08.022 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025983222
    465 rdf:type schema:CreativeWork
    466 https://doi.org/10.1016/j.biopsych.2017.11.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1092728036
    467 rdf:type schema:CreativeWork
    468 https://doi.org/10.1016/j.brainres.2011.04.020 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044902591
    469 rdf:type schema:CreativeWork
    470 https://doi.org/10.1016/j.concog.2016.02.005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019067841
    471 rdf:type schema:CreativeWork
    472 https://doi.org/10.1016/j.ejpn.2013.08.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000495295
    473 rdf:type schema:CreativeWork
    474 https://doi.org/10.1016/j.encep.2013.04.013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041964570
    475 rdf:type schema:CreativeWork
    476 https://doi.org/10.1016/j.encep.2014.08.007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027547472
    477 rdf:type schema:CreativeWork
    478 https://doi.org/10.1016/j.encep.2015.11.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011749481
    479 rdf:type schema:CreativeWork
    480 https://doi.org/10.1016/j.eurpsy.2007.02.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037546036
    481 rdf:type schema:CreativeWork
    482 https://doi.org/10.1016/j.eurpsy.2016.01.1698 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041086983
    483 rdf:type schema:CreativeWork
    484 https://doi.org/10.1016/j.expneurol.2008.04.019 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047462755
    485 rdf:type schema:CreativeWork
    486 https://doi.org/10.1016/j.jns.2013.07.2434 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024636367
    487 rdf:type schema:CreativeWork
    488 https://doi.org/10.1016/j.mcn.2014.06.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021062259
    489 rdf:type schema:CreativeWork
    490 https://doi.org/10.1016/j.nbd.2011.12.027 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028077223
    491 rdf:type schema:CreativeWork
    492 https://doi.org/10.1016/j.nbd.2014.03.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029333028
    493 rdf:type schema:CreativeWork
    494 https://doi.org/10.1016/j.nbd.2014.05.033 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039785101
    495 rdf:type schema:CreativeWork
    496 https://doi.org/10.1016/j.neubiorev.2006.02.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049601327
    497 rdf:type schema:CreativeWork
    498 https://doi.org/10.1016/j.neubiorev.2008.09.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042321270
    499 rdf:type schema:CreativeWork
    500 https://doi.org/10.1016/j.neubiorev.2009.12.009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048604076
    501 rdf:type schema:CreativeWork
    502 https://doi.org/10.1016/j.neubiorev.2015.01.013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007366619
    503 rdf:type schema:CreativeWork
    504 https://doi.org/10.1016/j.neulet.2011.03.097 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038171674
    505 rdf:type schema:CreativeWork
    506 https://doi.org/10.1016/j.neuron.2010.02.014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046952802
    507 rdf:type schema:CreativeWork
    508 https://doi.org/10.1016/j.neuron.2013.10.044 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017161088
    509 rdf:type schema:CreativeWork
    510 https://doi.org/10.1016/j.neuroscience.2010.02.033 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002124561
    511 rdf:type schema:CreativeWork
    512 https://doi.org/10.1016/j.pediatrneurol.2005.05.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050727689
    513 rdf:type schema:CreativeWork
    514 https://doi.org/10.1016/j.pediatrneurol.2014.07.028 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021565195
    515 rdf:type schema:CreativeWork
    516 https://doi.org/10.1016/j.pediatrneurol.2017.12.014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1100248593
    517 rdf:type schema:CreativeWork
    518 https://doi.org/10.1016/j.schres.2012.06.032 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052157932
    519 rdf:type schema:CreativeWork
    520 https://doi.org/10.1016/j.schres.2014.09.034 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015070478
    521 rdf:type schema:CreativeWork
    522 https://doi.org/10.1016/j.schres.2016.07.014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035043227
    523 rdf:type schema:CreativeWork
    524 https://doi.org/10.1016/j.ymgme.2009.06.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009639965
    525 rdf:type schema:CreativeWork
    526 https://doi.org/10.1016/j.ymgme.2009.07.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011314186
    527 rdf:type schema:CreativeWork
    528 https://doi.org/10.1016/j.ymgme.2009.12.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004339200
    529 rdf:type schema:CreativeWork
    530 https://doi.org/10.1016/j.ymgme.2012.03.012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027225530
    531 rdf:type schema:CreativeWork
    532 https://doi.org/10.1016/j.ymgme.2012.11.009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022284482
    533 rdf:type schema:CreativeWork
    534 https://doi.org/10.1016/j.ymgme.2016.06.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007294971
    535 rdf:type schema:CreativeWork
    536 https://doi.org/10.1016/s0014-4886(03)00345-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053067760
    537 rdf:type schema:CreativeWork
    538 https://doi.org/10.1016/s0022-510x(05)80295-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043197479
    539 rdf:type schema:CreativeWork
    540 https://doi.org/10.1016/s0042-6989(96)00066-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046292838
    541 rdf:type schema:CreativeWork
    542 https://doi.org/10.1016/s0074-7742(08)60346-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053342105
    543 rdf:type schema:CreativeWork
    544 https://doi.org/10.1016/s0140-6736(17)31465-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1091146813
    545 rdf:type schema:CreativeWork
    546 https://doi.org/10.1016/s0306-4522(01)00517-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006273125
    547 rdf:type schema:CreativeWork
    548 https://doi.org/10.1016/s0387-7604(01)00209-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047871344
    549 rdf:type schema:CreativeWork
    550 https://doi.org/10.1016/s0387-7604(01)00252-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043489527
    551 rdf:type schema:CreativeWork
    552 https://doi.org/10.1016/s0920-9964(00)00028-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028723164
    553 rdf:type schema:CreativeWork
    554 https://doi.org/10.1016/s1474-4422(07)70194-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021955671
    555 rdf:type schema:CreativeWork
    556 https://doi.org/10.1017/cbo9781139003872 schema:sameAs https://app.dimensions.ai/details/publication/pub.1108553816
    557 rdf:type schema:CreativeWork
    558 https://doi.org/10.1017/s0033291713000263 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053902670
    559 rdf:type schema:CreativeWork
    560 https://doi.org/10.1017/s1092852918001013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1105212416
    561 rdf:type schema:CreativeWork
    562 https://doi.org/10.1039/c3mt00308f schema:sameAs https://app.dimensions.ai/details/publication/pub.1028853123
    563 rdf:type schema:CreativeWork
    564 https://doi.org/10.1073/pnas.0402680101 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008422748
    565 rdf:type schema:CreativeWork
    566 https://doi.org/10.1073/pnas.1303346110 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046538513
    567 rdf:type schema:CreativeWork
    568 https://doi.org/10.1080/02643294.2017.1340264 schema:sameAs https://app.dimensions.ai/details/publication/pub.1090391568
    569 rdf:type schema:CreativeWork
    570 https://doi.org/10.1080/03007995.2017.1294054 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083777828
    571 rdf:type schema:CreativeWork
    572 https://doi.org/10.1080/15622975.2017.1379610 schema:sameAs https://app.dimensions.ai/details/publication/pub.1091787586
    573 rdf:type schema:CreativeWork
    574 https://doi.org/10.1080/15622975.2018.1441548 schema:sameAs https://app.dimensions.ai/details/publication/pub.1101114427
    575 rdf:type schema:CreativeWork
    576 https://doi.org/10.1083/jcb.201407122 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025837712
    577 rdf:type schema:CreativeWork
    578 https://doi.org/10.1093/brain/118.1.119 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059439416
    579 rdf:type schema:CreativeWork
    580 https://doi.org/10.1093/brain/121.4.561 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026910492
    581 rdf:type schema:CreativeWork
    582 https://doi.org/10.1093/brain/awh035 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021130268
    583 rdf:type schema:CreativeWork
    584 https://doi.org/10.1093/brain/awl260 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052588466
    585 rdf:type schema:CreativeWork
    586 https://doi.org/10.1093/brain/awu132 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053727728
    587 rdf:type schema:CreativeWork
    588 https://doi.org/10.1093/hmg/ddm100 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028741317
    589 rdf:type schema:CreativeWork
    590 https://doi.org/10.1093/jnen/60.1.49 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021971309
    591 rdf:type schema:CreativeWork
    592 https://doi.org/10.1093/jnen/63.6.660 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019053843
    593 rdf:type schema:CreativeWork
    594 https://doi.org/10.1093/schbul/4.4.636 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015558231
    595 rdf:type schema:CreativeWork
    596 https://doi.org/10.1093/schbul/sbq105 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024710792
    597 rdf:type schema:CreativeWork
    598 https://doi.org/10.1093/schbul/sbw100 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060024125
    599 rdf:type schema:CreativeWork
    600 https://doi.org/10.1097/nen.0000000000000045 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041867131
    601 rdf:type schema:CreativeWork
    602 https://doi.org/10.1098/rstb.2000.0734 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000408105
    603 rdf:type schema:CreativeWork
    604 https://doi.org/10.1101/mcs.a001222 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060407680
    605 rdf:type schema:CreativeWork
    606 https://doi.org/10.1111/j.1440-1614.2005.01678.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1044568580
    607 rdf:type schema:CreativeWork
    608 https://doi.org/10.1111/j.1440-1614.2006.01923.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1049525771
    609 rdf:type schema:CreativeWork
    610 https://doi.org/10.1111/j.1468-1331.2011.03545.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1048004560
    611 rdf:type schema:CreativeWork
    612 https://doi.org/10.1111/j.1469-8749.1998.tb15374.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1040699414
    613 rdf:type schema:CreativeWork
    614 https://doi.org/10.1111/j.1471-4159.2008.05657.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1030364055
    615 rdf:type schema:CreativeWork
    616 https://doi.org/10.1111/jnc.13138 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043717834
    617 rdf:type schema:CreativeWork
    618 https://doi.org/10.1126/science.283.5409.1908 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062564566
    619 rdf:type schema:CreativeWork
    620 https://doi.org/10.1126/scitranslmed.3010101 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012551405
    621 rdf:type schema:CreativeWork
    622 https://doi.org/10.1136/jnnp.74.4.528 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006640927
    623 rdf:type schema:CreativeWork
    624 https://doi.org/10.1155/2016/3830424 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030323750
    625 rdf:type schema:CreativeWork
    626 https://doi.org/10.1176/appi.ajp.162.5.1021-a schema:sameAs https://app.dimensions.ai/details/publication/pub.1063496620
    627 rdf:type schema:CreativeWork
    628 https://doi.org/10.1176/appi.ajp.2010.09081187 schema:sameAs https://app.dimensions.ai/details/publication/pub.1063498911
    629 rdf:type schema:CreativeWork
    630 https://doi.org/10.1176/appi.ajp.2013.13070981 schema:sameAs https://app.dimensions.ai/details/publication/pub.1063500115
    631 rdf:type schema:CreativeWork
    632 https://doi.org/10.1176/jnp.10.1.10 schema:sameAs https://app.dimensions.ai/details/publication/pub.1063511468
    633 rdf:type schema:CreativeWork
    634 https://doi.org/10.1176/jnp.15.3.289 schema:sameAs https://app.dimensions.ai/details/publication/pub.1063511980
    635 rdf:type schema:CreativeWork
    636 https://doi.org/10.1176/jnp.2006.18.2.158 schema:sameAs https://app.dimensions.ai/details/publication/pub.1063512344
    637 rdf:type schema:CreativeWork
    638 https://doi.org/10.1177/0891988713490992 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005905896
    639 rdf:type schema:CreativeWork
    640 https://doi.org/10.1192/apt.6.3.161 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004192359
    641 rdf:type schema:CreativeWork
    642 https://doi.org/10.1192/bjp.bp.108.057034 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050244785
    643 rdf:type schema:CreativeWork
    644 https://doi.org/10.1192/pb.bp.116.054072 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084737802
    645 rdf:type schema:CreativeWork
    646 https://doi.org/10.1212/01.wnl.0000345040.01917.9d schema:sameAs https://app.dimensions.ai/details/publication/pub.1064351055
    647 rdf:type schema:CreativeWork
    648 https://doi.org/10.1212/wnl.0b013e3181e6210e schema:sameAs https://app.dimensions.ai/details/publication/pub.1064355370
    649 rdf:type schema:CreativeWork
    650 https://doi.org/10.1212/wnl.0b013e3182563b82 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064356925
    651 rdf:type schema:CreativeWork
    652 https://doi.org/10.1212/wnl.45.9.1739 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064373540
    653 rdf:type schema:CreativeWork
    654 https://doi.org/10.12688/f1000research.12361.1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1101066894
    655 rdf:type schema:CreativeWork
    656 https://doi.org/10.1371/journal.pgen.1003462 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009838002
    657 rdf:type schema:CreativeWork
    658 https://doi.org/10.1371/journal.pone.0001049 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042196054
    659 rdf:type schema:CreativeWork
    660 https://doi.org/10.1523/jneurosci.1868-09.2009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052175671
    661 rdf:type schema:CreativeWork
    662 https://doi.org/10.1523/jneurosci.5981-10.2011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038491996
    663 rdf:type schema:CreativeWork
    664 https://doi.org/10.1586/ern.11.135 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045592968
    665 rdf:type schema:CreativeWork
    666 https://doi.org/10.2147/nedt.2006.2.4.531 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069103305
    667 rdf:type schema:CreativeWork
    668 https://doi.org/10.2217/clp.12.31 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052114177
    669 rdf:type schema:CreativeWork
    670 https://doi.org/10.3174/ajnr.a3356 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005616940
    671 rdf:type schema:CreativeWork
    672 https://doi.org/10.3389/fnbeh.2014.00393 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001258651
    673 rdf:type schema:CreativeWork
    674 https://doi.org/10.3389/fnins.2015.00177 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026485821
    675 rdf:type schema:CreativeWork
    676 https://doi.org/10.3389/fnmol.2017.00382 schema:sameAs https://app.dimensions.ai/details/publication/pub.1092743987
    677 rdf:type schema:CreativeWork
    678 https://doi.org/10.3389/fnsys.2015.00039 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030865365
    679 rdf:type schema:CreativeWork
    680 https://doi.org/10.3390/diseases4030029 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026540870
    681 rdf:type schema:CreativeWork
    682 https://doi.org/10.4324/9781315785011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039597806
    683 rdf:type schema:CreativeWork
    684 https://www.grid.ac/institutes/grid.1008.9 schema:alternateName University of Melbourne
    685 schema:name Department of Psychiatry, The University of Melbourne, Melbourne, VIC, Australia
    686 Neuropsychiatry Unit, The Royal Melbourne Hospital, Melbourne, VIC, Australia
    687 rdf:type schema:Organization
    688 https://www.grid.ac/institutes/grid.416153.4 schema:alternateName Royal Melbourne Hospital
    689 schema:name Neuropsychiatry Unit, The Royal Melbourne Hospital, Melbourne, VIC, Australia
    690 rdf:type schema:Organization
    691 https://www.grid.ac/institutes/grid.418025.a schema:alternateName Florey Institute of Neuroscience and Mental Health
    692 schema:name Department of Psychiatry, The University of Melbourne, Melbourne, VIC, Australia
    693 Florey Institute of Neuroscience and Mental Health, Melbourne, VIC, Australia
    694 Melbourne Neuropsychiatry Centre, University of Melbourne and Melbourne Health, Melbourne, VIC, Australia
    695 Neuropsychiatry Unit, The Royal Melbourne Hospital, Melbourne, VIC, Australia
    696 rdf:type schema:Organization
    697 https://www.grid.ac/institutes/grid.419789.a schema:alternateName Monash Health
    698 schema:name Movement Disorders Clinic, Kingston Centre, Monash Health, Cheltenham, VIC, Australia
    699 Neuropsychiatry Unit, The Royal Melbourne Hospital, Melbourne, VIC, Australia
    700 rdf:type schema:Organization
    701 https://www.grid.ac/institutes/grid.429299.d schema:alternateName Melbourne Health
    702 schema:name Department of Psychiatry, The University of Melbourne, Melbourne, VIC, Australia
    703 Melbourne Neuropsychiatry Centre, University of Melbourne and Melbourne Health, Melbourne, VIC, Australia
    704 Neuropsychiatry Unit, The Royal Melbourne Hospital, Melbourne, VIC, Australia
    705 rdf:type schema:Organization
    706 https://www.grid.ac/institutes/grid.429568.4 schema:alternateName National Ageing Research Institute
    707 schema:name Department of Psychiatry, The University of Melbourne, Melbourne, VIC, Australia
    708 National Ageing Research Institute, Melbourne, VIC, Australia
    709 Neuropsychiatry Unit, The Royal Melbourne Hospital, Melbourne, VIC, Australia
    710 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...