Anti-Anginal and Metabolic Effects of Carvedilol and Atenolol in Patients with Stable Angina Pectoris: A Prospective, Randomized, Parallel, Open-Label Study View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2016-06

AUTHORS

Pyung Chun Oh, Woong Chol Kang, Jeonggeun Moon, Yae Min Park, Sihun Kim, Myeong Gun Kim, Kyounghoon Lee, Taehoon Ahn, Eak Kyun Shin

ABSTRACT

BACKGROUND: While recent guidelines have suggested the potential for beta-blockers as first-line agents in chronic stable angina, few data regarding comparative anti-anginal and metabolic effects between beta-blockers with and without vasodilating properties have been reported, particularly in patients with angina pectoris. OBJECTIVE: Our objective was to compare the anti-anginal and metabolic effects of carvedilol and atenolol in patients with stable angina pectoris. METHODS: A total of 89 patients (mean age 54.9 ± 9.3 years; male 53.9 %) with stable angina pectoris were randomly assigned to carvedilol (n = 43) or atenolol (n = 46). The subjects undertook an exercise treadmill test and completed the Seattle Angina Questionnaire (SAQ); metabolic parameters were measured at baseline and 6 months after treatment. RESULTS: The baseline characteristics of both groups were well balanced. Both carvedilol and atenolol significantly reduced heart rate from baseline (76 ± 11 to 66 ± 9 beat/min, p < 0.001; 74 ± 9 to 64 ± 9 beat/min, p < 0.001, respectively) with no significant changes in systolic and diastolic blood pressure. Improvement of time to ST-segment depression during the treadmill exercise and the SAQ scores for angina stability and frequency after 6 months of treatment were similar between groups. There was no significant change from baseline in the level of fasting glucose, insulin, or glycated hemoglobin in either group. However, total cholesterol and low-density lipoprotein cholesterol levels significantly reduced to a greater extent with carvedilol than with atenolol (-23 vs. -10 and -38 vs. -24 %, respectively, p < 0.05 for both), although the rate of statin use was comparable. No changes were seen in high-density lipoprotein cholesterol and triglyceride levels after 6 months of treatment in both groups compared with baseline. CONCLUSIONS: Both carvedilol and atenolol had a similar anti-anginal effect. Compared with atenolol, carvedilol might have more beneficial effects on lipid metabolism in patients with stable angina pectoris [ClinicalTrials.gov identifier: NCT02547597]. More... »

PAGES

221-228

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s40256-016-0168-1

DOI

http://dx.doi.org/10.1007/s40256-016-0168-1

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1040442141

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/27021556


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adrenergic beta-1 Receptor Antagonists", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Angina, Stable", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Atenolol", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Carbazoles", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cardiotonic Agents", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cholesterol", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Exercise Test", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Heart", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Heart Rate", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hydroxymethylglutaryl-CoA Reductase Inhibitors", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hypercholesterolemia", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Insulin Resistance", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Myocardial Infarction", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Propanolamines", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Republic of Korea", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Risk", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Self Report", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Vasodilator Agents", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Gachon University Gil Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.411653.4", 
          "name": [
            "Cardiology, Gil Medical Center, Gachon University, 1198 Guwol-dong, Namdong-gu, 405-760, Incheon, Republic of Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Oh", 
        "givenName": "Pyung Chun", 
        "id": "sg:person.01356475310.58", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01356475310.58"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Gachon University Gil Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.411653.4", 
          "name": [
            "Cardiology, Gil Medical Center, Gachon University, 1198 Guwol-dong, Namdong-gu, 405-760, Incheon, Republic of Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kang", 
        "givenName": "Woong Chol", 
        "id": "sg:person.01236314066.78", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01236314066.78"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Gachon University Gil Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.411653.4", 
          "name": [
            "Cardiology, Gil Medical Center, Gachon University, 1198 Guwol-dong, Namdong-gu, 405-760, Incheon, Republic of Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Moon", 
        "givenName": "Jeonggeun", 
        "id": "sg:person.013757245472.76", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013757245472.76"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Gachon University Gil Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.411653.4", 
          "name": [
            "Cardiology, Gil Medical Center, Gachon University, 1198 Guwol-dong, Namdong-gu, 405-760, Incheon, Republic of Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Park", 
        "givenName": "Yae Min", 
        "id": "sg:person.01100320152.35", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01100320152.35"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Gachon University Gil Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.411653.4", 
          "name": [
            "Cardiology, Gil Medical Center, Gachon University, 1198 Guwol-dong, Namdong-gu, 405-760, Incheon, Republic of Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kim", 
        "givenName": "Sihun", 
        "id": "sg:person.01223166103.76", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01223166103.76"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Gachon University Gil Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.411653.4", 
          "name": [
            "Cardiology, Gil Medical Center, Gachon University, 1198 Guwol-dong, Namdong-gu, 405-760, Incheon, Republic of Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kim", 
        "givenName": "Myeong Gun", 
        "id": "sg:person.0640525571.48", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0640525571.48"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Gachon University Gil Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.411653.4", 
          "name": [
            "Cardiology, Gil Medical Center, Gachon University, 1198 Guwol-dong, Namdong-gu, 405-760, Incheon, Republic of Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lee", 
        "givenName": "Kyounghoon", 
        "id": "sg:person.01231067413.56", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01231067413.56"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Gachon University Gil Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.411653.4", 
          "name": [
            "Cardiology, Gil Medical Center, Gachon University, 1198 Guwol-dong, Namdong-gu, 405-760, Incheon, Republic of Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ahn", 
        "givenName": "Taehoon", 
        "id": "sg:person.07361634522.97", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07361634522.97"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Gachon University Gil Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.411653.4", 
          "name": [
            "Cardiology, Gil Medical Center, Gachon University, 1198 Guwol-dong, Namdong-gu, 405-760, Incheon, Republic of Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Shin", 
        "givenName": "Eak Kyun", 
        "id": "sg:person.015007160412.44", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015007160412.44"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1185/030079905x53306", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000196817"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1185/030079905x53306", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000196817"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejm200003303421301", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003405077"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/eurheartj/ehl001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011413064"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/qjmed/hcl059", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016004249"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0002-9343(80)90361-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017703105"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0002-9149(86)80010-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020584455"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/080370598437556", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021674674"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(86)90985-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026098042"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/archinte.159.6.551", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028919916"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jama.1988.03410140100032", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031615738"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0735-1097(02)02848-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034024908"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0735-1097(02)02848-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034024908"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejm198903163201105", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034071791"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1185/03007990903533681", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039695163"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.cir.88.4.1421", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044704145"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jama.292.18.2227", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048057103"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.cir.90.2.762", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048130178"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0735-1097(94)00397-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050546444"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(81)91101-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050590448"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(81)91101-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050590448"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0026-0495(94)90076-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051233469"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1055/s-2004-820915", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1057432084"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/eurheartj/12.suppl_d.60", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059574014"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00005344-199604000-00012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060205663"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00005344-199604000-00012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060205663"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00005344-199604000-00012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060205663"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/jcem.85.7.6661", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064323593"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/jcem.85.7.6661", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064323593"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2337/diacare.16.2.434", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1070745939"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.5688/aj710595", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1073069922"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074253405", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1080849747", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/ajh/7.2.129", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1082561308"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2016-06", 
    "datePublishedReg": "2016-06-01", 
    "description": "BACKGROUND: While recent guidelines have suggested the potential for beta-blockers as first-line agents in chronic stable angina, few data regarding comparative anti-anginal and metabolic effects between beta-blockers with and without vasodilating properties have been reported, particularly in patients with angina pectoris.\nOBJECTIVE: Our objective was to compare the anti-anginal and metabolic effects of carvedilol and atenolol in patients with stable angina pectoris.\nMETHODS: A total of 89 patients (mean age 54.9\u00a0\u00b1\u00a09.3\u00a0years; male 53.9\u00a0%) with stable angina pectoris were randomly assigned to carvedilol (n\u00a0=\u00a043) or atenolol (n\u00a0=\u00a046). The subjects undertook an exercise treadmill test and completed the Seattle Angina Questionnaire (SAQ); metabolic parameters were measured at baseline and 6\u00a0months after treatment.\nRESULTS: The baseline characteristics of both groups were well balanced. Both carvedilol and atenolol significantly reduced heart rate from baseline (76 \u00b1 11 to 66 \u00b1 9 beat/min, p < 0.001; 74 \u00b1 9 to 64 \u00b1 9 beat/min, p < 0.001, respectively) with no significant changes in systolic and diastolic blood pressure. Improvement of time to ST-segment depression during the treadmill exercise and the SAQ scores for angina stability and frequency after 6\u00a0months of treatment were similar between groups. There was no significant change from baseline in the level of fasting glucose, insulin, or glycated hemoglobin in either group. However, total cholesterol and low-density lipoprotein cholesterol levels significantly reduced to a greater extent with carvedilol than with atenolol (-23 vs. -10 and -38 vs. -24 %, respectively, p\u00a0<\u00a00.05 for both), although the rate of statin use was comparable. No changes were seen in high-density lipoprotein cholesterol and triglyceride levels after 6\u00a0months of treatment in both groups compared with baseline.\nCONCLUSIONS: Both carvedilol and atenolol had a similar anti-anginal effect. Compared with atenolol, carvedilol might have more beneficial effects on lipid metabolism in patients with stable angina pectoris [ClinicalTrials.gov identifier: NCT02547597].", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s40256-016-0168-1", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1024601", 
        "issn": [
          "1175-3277", 
          "1179-187X"
        ], 
        "name": "American Journal of Cardiovascular Drugs", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "3", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "16"
      }
    ], 
    "name": "Anti-Anginal and Metabolic Effects of Carvedilol and Atenolol in Patients with Stable Angina Pectoris: A Prospective, Randomized, Parallel, Open-Label Study", 
    "pagination": "221-228", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "c0a61f57ae9d4f24caf8164f275af59be51360f046cc2353fc5a5d728bfb79a7"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "27021556"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "100967755"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s40256-016-0168-1"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1040442141"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s40256-016-0168-1", 
      "https://app.dimensions.ai/details/publication/pub.1040442141"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T19:11", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8678_00000523.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007%2Fs40256-016-0168-1"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s40256-016-0168-1'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s40256-016-0168-1'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s40256-016-0168-1'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s40256-016-0168-1'


 

This table displays all metadata directly associated to this object as RDF triples.

299 TRIPLES      21 PREDICATES      80 URIs      44 LITERALS      32 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s40256-016-0168-1 schema:about N09875957f8014e66aecbcd501b6c497e
2 N0b0cb58550824be48dfe4af9974e5a7e
3 N37f3a218a33d46d48c21029b4ca4c9aa
4 N3de747e1119d46c29e23d29bbc5dc1b4
5 N45e70b8691e1405bb1fe3a47ff06434c
6 N5134c39236d34d50bd9b78563b0878d8
7 N572d498a36bf41a2a09d8868b2f35f2a
8 N5d91cea93bb04547a1100ec073cf0dbd
9 N6b135e33abbc45bc82353f0297bb4ff7
10 N6b3377ca5c554b0ea5721ff202b489d3
11 N7c3d441a41384a478a3db951f899209c
12 N9def1bec1d0a45e39b4279895797f2e8
13 Na5779eda997e4ac086ae77cd37506dc5
14 Nab66864dcf204ec48b854f2dd45e792b
15 Nd40916c324cc4d3ca70a6d20f5b73abe
16 Nda4ef0f8df3e459bbc71f828382d2c7d
17 Ndd90f699e9ac4dbeac97f77cdfe5ae58
18 Ndf3847602af245e48d676ca3909c0b48
19 Ne74218fa438a4ff79b6db5e0b1ac70af
20 Nebf83aa97df04e2b8ba6d15250294621
21 Nee3696a28b1a454691e503a5c339c763
22 Nf330700955cc4a93b787357de8bded2f
23 Nf88d6b7c2b504b03814fe4a8bef8d426
24 anzsrc-for:11
25 anzsrc-for:1103
26 schema:author N4016399dcdf149eabdbb8c1443c84dec
27 schema:citation https://app.dimensions.ai/details/publication/pub.1074253405
28 https://app.dimensions.ai/details/publication/pub.1080849747
29 https://doi.org/10.1001/archinte.159.6.551
30 https://doi.org/10.1001/jama.1988.03410140100032
31 https://doi.org/10.1001/jama.292.18.2227
32 https://doi.org/10.1016/0002-9343(80)90361-7
33 https://doi.org/10.1016/0026-0495(94)90076-0
34 https://doi.org/10.1016/0735-1097(94)00397-9
35 https://doi.org/10.1016/s0002-9149(86)80010-8
36 https://doi.org/10.1016/s0140-6736(81)91101-6
37 https://doi.org/10.1016/s0140-6736(86)90985-2
38 https://doi.org/10.1016/s0735-1097(02)02848-6
39 https://doi.org/10.1055/s-2004-820915
40 https://doi.org/10.1056/nejm198903163201105
41 https://doi.org/10.1056/nejm200003303421301
42 https://doi.org/10.1080/080370598437556
43 https://doi.org/10.1093/ajh/7.2.129
44 https://doi.org/10.1093/eurheartj/12.suppl_d.60
45 https://doi.org/10.1093/eurheartj/ehl001
46 https://doi.org/10.1093/qjmed/hcl059
47 https://doi.org/10.1097/00005344-199604000-00012
48 https://doi.org/10.1161/01.cir.88.4.1421
49 https://doi.org/10.1161/01.cir.90.2.762
50 https://doi.org/10.1185/030079905x53306
51 https://doi.org/10.1185/03007990903533681
52 https://doi.org/10.1210/jcem.85.7.6661
53 https://doi.org/10.2337/diacare.16.2.434
54 https://doi.org/10.5688/aj710595
55 schema:datePublished 2016-06
56 schema:datePublishedReg 2016-06-01
57 schema:description BACKGROUND: While recent guidelines have suggested the potential for beta-blockers as first-line agents in chronic stable angina, few data regarding comparative anti-anginal and metabolic effects between beta-blockers with and without vasodilating properties have been reported, particularly in patients with angina pectoris. OBJECTIVE: Our objective was to compare the anti-anginal and metabolic effects of carvedilol and atenolol in patients with stable angina pectoris. METHODS: A total of 89 patients (mean age 54.9 ± 9.3 years; male 53.9 %) with stable angina pectoris were randomly assigned to carvedilol (n = 43) or atenolol (n = 46). The subjects undertook an exercise treadmill test and completed the Seattle Angina Questionnaire (SAQ); metabolic parameters were measured at baseline and 6 months after treatment. RESULTS: The baseline characteristics of both groups were well balanced. Both carvedilol and atenolol significantly reduced heart rate from baseline (76 ± 11 to 66 ± 9 beat/min, p < 0.001; 74 ± 9 to 64 ± 9 beat/min, p < 0.001, respectively) with no significant changes in systolic and diastolic blood pressure. Improvement of time to ST-segment depression during the treadmill exercise and the SAQ scores for angina stability and frequency after 6 months of treatment were similar between groups. There was no significant change from baseline in the level of fasting glucose, insulin, or glycated hemoglobin in either group. However, total cholesterol and low-density lipoprotein cholesterol levels significantly reduced to a greater extent with carvedilol than with atenolol (-23 vs. -10 and -38 vs. -24 %, respectively, p < 0.05 for both), although the rate of statin use was comparable. No changes were seen in high-density lipoprotein cholesterol and triglyceride levels after 6 months of treatment in both groups compared with baseline. CONCLUSIONS: Both carvedilol and atenolol had a similar anti-anginal effect. Compared with atenolol, carvedilol might have more beneficial effects on lipid metabolism in patients with stable angina pectoris [ClinicalTrials.gov identifier: NCT02547597].
58 schema:genre research_article
59 schema:inLanguage en
60 schema:isAccessibleForFree false
61 schema:isPartOf N8f51596130d14ac9848954adec336da9
62 Nf8765b29febf4008bb59628c88546f1d
63 sg:journal.1024601
64 schema:name Anti-Anginal and Metabolic Effects of Carvedilol and Atenolol in Patients with Stable Angina Pectoris: A Prospective, Randomized, Parallel, Open-Label Study
65 schema:pagination 221-228
66 schema:productId N1daeffd26b1d4816b6adfe30e4251a03
67 N4d27142a54f44b6eb7d302d08a35673d
68 N8c91901ab23849b2903da59133750f4a
69 Nb999a1a77588457a94b21bf01f1a91b6
70 Nc2b99eff4fcb4a009f4562a5d0387f45
71 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040442141
72 https://doi.org/10.1007/s40256-016-0168-1
73 schema:sdDatePublished 2019-04-10T19:11
74 schema:sdLicense https://scigraph.springernature.com/explorer/license/
75 schema:sdPublisher N013d3735b2c2471ea290eb9754e625b1
76 schema:url http://link.springer.com/10.1007%2Fs40256-016-0168-1
77 sgo:license sg:explorer/license/
78 sgo:sdDataset articles
79 rdf:type schema:ScholarlyArticle
80 N013d3735b2c2471ea290eb9754e625b1 schema:name Springer Nature - SN SciGraph project
81 rdf:type schema:Organization
82 N09875957f8014e66aecbcd501b6c497e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
83 schema:name Heart Rate
84 rdf:type schema:DefinedTerm
85 N0b0cb58550824be48dfe4af9974e5a7e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
86 schema:name Hypercholesterolemia
87 rdf:type schema:DefinedTerm
88 N1daeffd26b1d4816b6adfe30e4251a03 schema:name dimensions_id
89 schema:value pub.1040442141
90 rdf:type schema:PropertyValue
91 N28cf824bbc7c43d486d8aefd1ea79321 rdf:first sg:person.01236314066.78
92 rdf:rest N6fa2a12f88c941528e821d7eb1bcb61f
93 N34a49503c7d5471eb794d2e1fa294163 rdf:first sg:person.0640525571.48
94 rdf:rest N54d1b5b608764cbf87f9e0d50e393a18
95 N37f3a218a33d46d48c21029b4ca4c9aa schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
96 schema:name Adrenergic beta-1 Receptor Antagonists
97 rdf:type schema:DefinedTerm
98 N3de747e1119d46c29e23d29bbc5dc1b4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
99 schema:name Cardiotonic Agents
100 rdf:type schema:DefinedTerm
101 N4016399dcdf149eabdbb8c1443c84dec rdf:first sg:person.01356475310.58
102 rdf:rest N28cf824bbc7c43d486d8aefd1ea79321
103 N40fcf280fac54c6ba600a6c935b42a52 rdf:first sg:person.07361634522.97
104 rdf:rest Nad30c9d3f5af498cb7217bc8525ae6da
105 N45e70b8691e1405bb1fe3a47ff06434c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
106 schema:name Male
107 rdf:type schema:DefinedTerm
108 N4d27142a54f44b6eb7d302d08a35673d schema:name readcube_id
109 schema:value c0a61f57ae9d4f24caf8164f275af59be51360f046cc2353fc5a5d728bfb79a7
110 rdf:type schema:PropertyValue
111 N5134c39236d34d50bd9b78563b0878d8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
112 schema:name Hydroxymethylglutaryl-CoA Reductase Inhibitors
113 rdf:type schema:DefinedTerm
114 N54d1b5b608764cbf87f9e0d50e393a18 rdf:first sg:person.01231067413.56
115 rdf:rest N40fcf280fac54c6ba600a6c935b42a52
116 N572d498a36bf41a2a09d8868b2f35f2a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
117 schema:name Heart
118 rdf:type schema:DefinedTerm
119 N5d91cea93bb04547a1100ec073cf0dbd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
120 schema:name Middle Aged
121 rdf:type schema:DefinedTerm
122 N6b135e33abbc45bc82353f0297bb4ff7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
123 schema:name Self Report
124 rdf:type schema:DefinedTerm
125 N6b3377ca5c554b0ea5721ff202b489d3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
126 schema:name Vasodilator Agents
127 rdf:type schema:DefinedTerm
128 N6fa2a12f88c941528e821d7eb1bcb61f rdf:first sg:person.013757245472.76
129 rdf:rest Nb382d3e74804482bb40995f352e67201
130 N7c3d441a41384a478a3db951f899209c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
131 schema:name Risk
132 rdf:type schema:DefinedTerm
133 N8c91901ab23849b2903da59133750f4a schema:name pubmed_id
134 schema:value 27021556
135 rdf:type schema:PropertyValue
136 N8f51596130d14ac9848954adec336da9 schema:volumeNumber 16
137 rdf:type schema:PublicationVolume
138 N9def1bec1d0a45e39b4279895797f2e8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
139 schema:name Humans
140 rdf:type schema:DefinedTerm
141 Na5779eda997e4ac086ae77cd37506dc5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
142 schema:name Exercise Test
143 rdf:type schema:DefinedTerm
144 Nab66864dcf204ec48b854f2dd45e792b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
145 schema:name Propanolamines
146 rdf:type schema:DefinedTerm
147 Nad30c9d3f5af498cb7217bc8525ae6da rdf:first sg:person.015007160412.44
148 rdf:rest rdf:nil
149 Nb382d3e74804482bb40995f352e67201 rdf:first sg:person.01100320152.35
150 rdf:rest Nf353799d00db4c72a28cd3c1a496f50e
151 Nb999a1a77588457a94b21bf01f1a91b6 schema:name doi
152 schema:value 10.1007/s40256-016-0168-1
153 rdf:type schema:PropertyValue
154 Nc2b99eff4fcb4a009f4562a5d0387f45 schema:name nlm_unique_id
155 schema:value 100967755
156 rdf:type schema:PropertyValue
157 Nd40916c324cc4d3ca70a6d20f5b73abe schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
158 schema:name Angina, Stable
159 rdf:type schema:DefinedTerm
160 Nda4ef0f8df3e459bbc71f828382d2c7d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
161 schema:name Cholesterol
162 rdf:type schema:DefinedTerm
163 Ndd90f699e9ac4dbeac97f77cdfe5ae58 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
164 schema:name Carbazoles
165 rdf:type schema:DefinedTerm
166 Ndf3847602af245e48d676ca3909c0b48 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
167 schema:name Aged
168 rdf:type schema:DefinedTerm
169 Ne74218fa438a4ff79b6db5e0b1ac70af schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
170 schema:name Republic of Korea
171 rdf:type schema:DefinedTerm
172 Nebf83aa97df04e2b8ba6d15250294621 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
173 schema:name Myocardial Infarction
174 rdf:type schema:DefinedTerm
175 Nee3696a28b1a454691e503a5c339c763 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
176 schema:name Atenolol
177 rdf:type schema:DefinedTerm
178 Nf330700955cc4a93b787357de8bded2f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
179 schema:name Female
180 rdf:type schema:DefinedTerm
181 Nf353799d00db4c72a28cd3c1a496f50e rdf:first sg:person.01223166103.76
182 rdf:rest N34a49503c7d5471eb794d2e1fa294163
183 Nf8765b29febf4008bb59628c88546f1d schema:issueNumber 3
184 rdf:type schema:PublicationIssue
185 Nf88d6b7c2b504b03814fe4a8bef8d426 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
186 schema:name Insulin Resistance
187 rdf:type schema:DefinedTerm
188 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
189 schema:name Medical and Health Sciences
190 rdf:type schema:DefinedTerm
191 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
192 schema:name Clinical Sciences
193 rdf:type schema:DefinedTerm
194 sg:journal.1024601 schema:issn 1175-3277
195 1179-187X
196 schema:name American Journal of Cardiovascular Drugs
197 rdf:type schema:Periodical
198 sg:person.01100320152.35 schema:affiliation https://www.grid.ac/institutes/grid.411653.4
199 schema:familyName Park
200 schema:givenName Yae Min
201 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01100320152.35
202 rdf:type schema:Person
203 sg:person.01223166103.76 schema:affiliation https://www.grid.ac/institutes/grid.411653.4
204 schema:familyName Kim
205 schema:givenName Sihun
206 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01223166103.76
207 rdf:type schema:Person
208 sg:person.01231067413.56 schema:affiliation https://www.grid.ac/institutes/grid.411653.4
209 schema:familyName Lee
210 schema:givenName Kyounghoon
211 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01231067413.56
212 rdf:type schema:Person
213 sg:person.01236314066.78 schema:affiliation https://www.grid.ac/institutes/grid.411653.4
214 schema:familyName Kang
215 schema:givenName Woong Chol
216 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01236314066.78
217 rdf:type schema:Person
218 sg:person.01356475310.58 schema:affiliation https://www.grid.ac/institutes/grid.411653.4
219 schema:familyName Oh
220 schema:givenName Pyung Chun
221 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01356475310.58
222 rdf:type schema:Person
223 sg:person.013757245472.76 schema:affiliation https://www.grid.ac/institutes/grid.411653.4
224 schema:familyName Moon
225 schema:givenName Jeonggeun
226 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013757245472.76
227 rdf:type schema:Person
228 sg:person.015007160412.44 schema:affiliation https://www.grid.ac/institutes/grid.411653.4
229 schema:familyName Shin
230 schema:givenName Eak Kyun
231 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015007160412.44
232 rdf:type schema:Person
233 sg:person.0640525571.48 schema:affiliation https://www.grid.ac/institutes/grid.411653.4
234 schema:familyName Kim
235 schema:givenName Myeong Gun
236 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0640525571.48
237 rdf:type schema:Person
238 sg:person.07361634522.97 schema:affiliation https://www.grid.ac/institutes/grid.411653.4
239 schema:familyName Ahn
240 schema:givenName Taehoon
241 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07361634522.97
242 rdf:type schema:Person
243 https://app.dimensions.ai/details/publication/pub.1074253405 schema:CreativeWork
244 https://app.dimensions.ai/details/publication/pub.1080849747 schema:CreativeWork
245 https://doi.org/10.1001/archinte.159.6.551 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028919916
246 rdf:type schema:CreativeWork
247 https://doi.org/10.1001/jama.1988.03410140100032 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031615738
248 rdf:type schema:CreativeWork
249 https://doi.org/10.1001/jama.292.18.2227 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048057103
250 rdf:type schema:CreativeWork
251 https://doi.org/10.1016/0002-9343(80)90361-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017703105
252 rdf:type schema:CreativeWork
253 https://doi.org/10.1016/0026-0495(94)90076-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051233469
254 rdf:type schema:CreativeWork
255 https://doi.org/10.1016/0735-1097(94)00397-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050546444
256 rdf:type schema:CreativeWork
257 https://doi.org/10.1016/s0002-9149(86)80010-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020584455
258 rdf:type schema:CreativeWork
259 https://doi.org/10.1016/s0140-6736(81)91101-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050590448
260 rdf:type schema:CreativeWork
261 https://doi.org/10.1016/s0140-6736(86)90985-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026098042
262 rdf:type schema:CreativeWork
263 https://doi.org/10.1016/s0735-1097(02)02848-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034024908
264 rdf:type schema:CreativeWork
265 https://doi.org/10.1055/s-2004-820915 schema:sameAs https://app.dimensions.ai/details/publication/pub.1057432084
266 rdf:type schema:CreativeWork
267 https://doi.org/10.1056/nejm198903163201105 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034071791
268 rdf:type schema:CreativeWork
269 https://doi.org/10.1056/nejm200003303421301 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003405077
270 rdf:type schema:CreativeWork
271 https://doi.org/10.1080/080370598437556 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021674674
272 rdf:type schema:CreativeWork
273 https://doi.org/10.1093/ajh/7.2.129 schema:sameAs https://app.dimensions.ai/details/publication/pub.1082561308
274 rdf:type schema:CreativeWork
275 https://doi.org/10.1093/eurheartj/12.suppl_d.60 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059574014
276 rdf:type schema:CreativeWork
277 https://doi.org/10.1093/eurheartj/ehl001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011413064
278 rdf:type schema:CreativeWork
279 https://doi.org/10.1093/qjmed/hcl059 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016004249
280 rdf:type schema:CreativeWork
281 https://doi.org/10.1097/00005344-199604000-00012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060205663
282 rdf:type schema:CreativeWork
283 https://doi.org/10.1161/01.cir.88.4.1421 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044704145
284 rdf:type schema:CreativeWork
285 https://doi.org/10.1161/01.cir.90.2.762 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048130178
286 rdf:type schema:CreativeWork
287 https://doi.org/10.1185/030079905x53306 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000196817
288 rdf:type schema:CreativeWork
289 https://doi.org/10.1185/03007990903533681 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039695163
290 rdf:type schema:CreativeWork
291 https://doi.org/10.1210/jcem.85.7.6661 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064323593
292 rdf:type schema:CreativeWork
293 https://doi.org/10.2337/diacare.16.2.434 schema:sameAs https://app.dimensions.ai/details/publication/pub.1070745939
294 rdf:type schema:CreativeWork
295 https://doi.org/10.5688/aj710595 schema:sameAs https://app.dimensions.ai/details/publication/pub.1073069922
296 rdf:type schema:CreativeWork
297 https://www.grid.ac/institutes/grid.411653.4 schema:alternateName Gachon University Gil Medical Center
298 schema:name Cardiology, Gil Medical Center, Gachon University, 1198 Guwol-dong, Namdong-gu, 405-760, Incheon, Republic of Korea
299 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...