Polyurethane synthesis for vascular application View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2018-12

AUTHORS

Zahra Zaredar, Fahimeh Askari, Parvin Shokrolahi

ABSTRACT

Three polyurethane formulations were prepared on the basis of siloxane; two formulations contained 1% and 3% of a hydroxyl functionalized polyhedral oligomeric silsesquioxane [POSS (ROH)2] nano-particles (as a co-chain extender) and one was without nano-particle. Structures of the polyurethanes were characterized by FTIR and SEM. The effect of POSS nano-particles on properties of the synthesized PUs was examined for vascular applications by tensile test, contact angle, SEM, AFM and endothelial cells viability evaluation. Properties of the polyurethane with 1% POSS were compared with those of PU without POSS and the results showed 66% increase in the elongation-at-break, 53% increase in tensile strength and 33% increase in modulus, 9.45% increase in contact angle, 76.7% reduction in surface roughness and 9.46% increase in cell viability. It was also shown that a polyurethane containing 1% of POSS nano-particles in its structure developed the highest hydrophobicity, which resulted in its lowest potential for thrombosis. More... »

PAGES

1-10

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s40204-018-0101-6

DOI

http://dx.doi.org/10.1007/s40204-018-0101-6

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1107768353

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30349979


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