Prosopis farcta Extract Potentiates the Scolicidal Activity Against Protoscolices of Hydatid Cysts View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2021-11-16

AUTHORS

Mohammad Hasan Namaei, Rahmat Solgi, Amir Tavakoli Kareshk

ABSTRACT

This study aimed to assess the efficacy of methanolic extract of Prosopis farcta (P. farcta) against protoscolices. In this study, the liver of sheep infected with hydatid cyst was collected from Birjand abattoir and after isolation of hydatid cyst protoscolices, to assess the protoscolicidal effect of P. farcta, concentrations of 250, 500, 1000 mg/ml Lit a liter of plant extract with a suspension of protoscolices and their mortality was calculated in 5 to 30 min. The metabolites in the P. farcta extract were characterized by gas chromatography-mass spectrometry (GC–MS). The average of the mortality protoscoleces was 100% after 5 min of incubation with the concentration of 1000 mg/ml of P. farcta extract. The mean of the mortality of protoscoleces after 10 min of incubation with the concentration of 500 mg/ml of P. farcta extract was 100%. That is, P. farcta extract requires a longer length of time to display potent protoscolicidal effects. The results of this investigation revealed that P. farcta extract could have a significant scolicidal activity on hydatid cyst protoscoleces. However, further research that must be accomplished particularly in human and animal subjects is required to reach this conclusion. More... »

PAGES

57-62

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s40011-021-01274-7

DOI

http://dx.doi.org/10.1007/s40011-021-01274-7

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1142610516


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