A Gelucire 44/14 and labrasol based solid self emulsifying drug delivery system: formulation and evaluation View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2013-06

AUTHORS

Venkata Raman Kallakunta, Basanth Babu Eedara, Raju Jukanti, Ram Kishan Ajmeera, Suresh Bandari

ABSTRACT

A solid self emulsifying formulation (S-SEF) has been developed with an intention to improve the dissolution characteristics of poorly water soluble lercanidipine hydrochloride (LH). Suitable components for the formulation of liquid self emulsifying drug delivery systems (SEDDS) were selected after screening various vehicles via solubility studies. Formulations were designed with Gelucire® 44/14 as oil, labrasol as surfactant and transcutol-P as co surfactant. The prepared formulations were evaluated for self emulsifying efficiency and ternary phase diagram was used to designate optimum systems in the emulsifying domain. These systems were further investigated for robustness towards different pH conditions, globule size, thermodynamic stability, surface morphology, cloud point and in vitro drug release. The optimized LH loaded formulation possessed a mean globule size of 142.5 ± 5.37 nm and cloud point of 72 ± 2.66 °C. The liquid SEDDS was transformed into free flowing S-SEF by adsorbing on to an inert carrier, Neusilin US2®. The results revealed no difference in globule size and emulsification characteristics between liquid SEDDS and S-SEF. The solid state characterization studies indicated loss of crystallinity for the drug. Significant improvement in dissolution characteristics of LH for prepared S-SEF was observed compared with pure drug. More... »

PAGES

185-196

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s40005-013-0060-9

DOI

http://dx.doi.org/10.1007/s40005-013-0060-9

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1037818326


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0306", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Physical Chemistry (incl. Structural)", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/03", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Chemical Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Kakatiya University", 
          "id": "https://www.grid.ac/institutes/grid.411990.4", 
          "name": [
            "Department of Pharmaceutics, St. Peter\u2019s Institute of Pharmaceutical Sciences, Hanamkonda, Vidyanagar, 506001, Warangal, Andhra Pradesh, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kallakunta", 
        "givenName": "Venkata Raman", 
        "id": "sg:person.010136420127.24", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010136420127.24"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kakatiya University", 
          "id": "https://www.grid.ac/institutes/grid.411990.4", 
          "name": [
            "Department of Pharmaceutics, St. Peter\u2019s Institute of Pharmaceutical Sciences, Hanamkonda, Vidyanagar, 506001, Warangal, Andhra Pradesh, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Eedara", 
        "givenName": "Basanth Babu", 
        "id": "sg:person.01314563300.01", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01314563300.01"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kakatiya University", 
          "id": "https://www.grid.ac/institutes/grid.411990.4", 
          "name": [
            "Department of Pharmaceutics, St. Peter\u2019s Institute of Pharmaceutical Sciences, Hanamkonda, Vidyanagar, 506001, Warangal, Andhra Pradesh, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Jukanti", 
        "givenName": "Raju", 
        "id": "sg:person.0725567676.59", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0725567676.59"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kakatiya University", 
          "id": "https://www.grid.ac/institutes/grid.411990.4", 
          "name": [
            "Department of Pharmaceutics, St. Peter\u2019s Institute of Pharmaceutical Sciences, Hanamkonda, Vidyanagar, 506001, Warangal, Andhra Pradesh, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ajmeera", 
        "givenName": "Ram Kishan", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kakatiya University", 
          "id": "https://www.grid.ac/institutes/grid.411990.4", 
          "name": [
            "Department of Pharmaceutics, St. Peter\u2019s Institute of Pharmaceutical Sciences, Hanamkonda, Vidyanagar, 506001, Warangal, Andhra Pradesh, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bandari", 
        "givenName": "Suresh", 
        "id": "sg:person.01207730101.26", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01207730101.26"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1208/pt050342", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000740796", 
          "https://doi.org/10.1208/pt050342"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1527-3466.1997.tb00331.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001127991"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1527-3466.1997.tb00331.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001127991"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0169-409x(00)00129-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006677292"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3109/03639049709150551", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007277854"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.addr.2007.05.006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008039331"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02977782", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011279324", 
          "https://doi.org/10.1007/bf02977782"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02977782", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011279324", 
          "https://doi.org/10.1007/bf02977782"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.biopha.2004.02.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012015777"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jconrel.2006.05.010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012699535"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0939-6411(00)00087-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013506980"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ejpb.2006.10.014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016279393"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1081/ddc-100101263", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016583559"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ejps.2009.12.004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017607757"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0378-5173(94)00222-q", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020243805"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.colsurfb.2009.01.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020299861"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0169-409x(00)00103-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022127682"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0939-6411(03)00142-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026253698"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0939-6411(03)00142-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026253698"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.2042-7158.1975.tb09378.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027829664"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0168-3659(02)00050-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029061926"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0378-5173(90)90381-d", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030419691"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0378-5173(90)90381-d", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030419691"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0024-3205(01)01375-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032375929"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ejpb.2005.12.005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032501114"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1023/a:1018987928936", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034450606", 
          "https://doi.org/10.1023/a:1018987928936"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/10408390591000884", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034820372"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0169-409x(96)00494-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037307232"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jps.2600550409", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037523533"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jps.2600821002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038157945"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ijpharm.2007.12.026", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038515955"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ejps.2008.06.013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040520971"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ijpharm.2009.07.015", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043103882"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11095-007-9304-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045071125", 
          "https://doi.org/10.1007/s11095-007-9304-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1749-6632.1961.tb44987.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046472609"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ejps.2004.08.003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052134817"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0168-3659(03)00261-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052820587"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0168-3659(03)00261-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052820587"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/la000493l", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1056139367"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/la000493l", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1056139367"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/la990856l", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1056171482"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/la990856l", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1056171482"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083391384", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2013-06", 
    "datePublishedReg": "2013-06-01", 
    "description": "A solid self emulsifying formulation (S-SEF) has been developed with an intention to improve the dissolution characteristics of poorly water soluble lercanidipine hydrochloride (LH). Suitable components for the formulation of liquid self emulsifying drug delivery systems (SEDDS) were selected after screening various vehicles via solubility studies. Formulations were designed with Gelucire\u00ae 44/14 as oil, labrasol as surfactant and transcutol-P as co surfactant. The prepared formulations were evaluated for self emulsifying efficiency and ternary phase diagram was used to designate optimum systems in the emulsifying domain. These systems were further investigated for robustness towards different pH conditions, globule size, thermodynamic stability, surface morphology, cloud point and in vitro drug release. The optimized LH loaded formulation possessed a mean globule size of 142.5 \u00b1 5.37 nm and cloud point of 72 \u00b1 2.66 \u00b0C. The liquid SEDDS was transformed into free flowing S-SEF by adsorbing on to an inert carrier, Neusilin US2\u00ae. The results revealed no difference in globule size and emulsification characteristics between liquid SEDDS and S-SEF. The solid state characterization studies indicated loss of crystallinity for the drug. Significant improvement in dissolution characteristics of LH for prepared S-SEF was observed compared with pure drug.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s40005-013-0060-9", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1044391", 
        "issn": [
          "2093-5552", 
          "2093-6214"
        ], 
        "name": "Journal of Pharmaceutical Investigation", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "3", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "43"
      }
    ], 
    "name": "A Gelucire 44/14 and labrasol based solid self emulsifying drug delivery system: formulation and evaluation", 
    "pagination": "185-196", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "b42828c76f00d066bddc82103c3c208be2417c3f1909527d1b212f36865f2e1f"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s40005-013-0060-9"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1037818326"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s40005-013-0060-9", 
      "https://app.dimensions.ai/details/publication/pub.1037818326"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T17:34", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8672_00000523.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007%2Fs40005-013-0060-9"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s40005-013-0060-9'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s40005-013-0060-9'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s40005-013-0060-9'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s40005-013-0060-9'


 

This table displays all metadata directly associated to this object as RDF triples.

199 TRIPLES      21 PREDICATES      63 URIs      19 LITERALS      7 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s40005-013-0060-9 schema:about anzsrc-for:03
2 anzsrc-for:0306
3 schema:author Nae4100d3e6d6441aaac6232ff3e2dc3b
4 schema:citation sg:pub.10.1007/bf02977782
5 sg:pub.10.1007/s11095-007-9304-6
6 sg:pub.10.1023/a:1018987928936
7 sg:pub.10.1208/pt050342
8 https://app.dimensions.ai/details/publication/pub.1083391384
9 https://doi.org/10.1002/jps.2600550409
10 https://doi.org/10.1002/jps.2600821002
11 https://doi.org/10.1016/0378-5173(90)90381-d
12 https://doi.org/10.1016/0378-5173(94)00222-q
13 https://doi.org/10.1016/j.addr.2007.05.006
14 https://doi.org/10.1016/j.biopha.2004.02.001
15 https://doi.org/10.1016/j.colsurfb.2009.01.008
16 https://doi.org/10.1016/j.ejpb.2005.12.005
17 https://doi.org/10.1016/j.ejpb.2006.10.014
18 https://doi.org/10.1016/j.ejps.2004.08.003
19 https://doi.org/10.1016/j.ejps.2008.06.013
20 https://doi.org/10.1016/j.ejps.2009.12.004
21 https://doi.org/10.1016/j.ijpharm.2007.12.026
22 https://doi.org/10.1016/j.ijpharm.2009.07.015
23 https://doi.org/10.1016/j.jconrel.2006.05.010
24 https://doi.org/10.1016/s0024-3205(01)01375-3
25 https://doi.org/10.1016/s0168-3659(02)00050-0
26 https://doi.org/10.1016/s0168-3659(03)00261-x
27 https://doi.org/10.1016/s0169-409x(00)00103-4
28 https://doi.org/10.1016/s0169-409x(00)00129-0
29 https://doi.org/10.1016/s0169-409x(96)00494-2
30 https://doi.org/10.1016/s0939-6411(00)00087-4
31 https://doi.org/10.1016/s0939-6411(03)00142-5
32 https://doi.org/10.1021/la000493l
33 https://doi.org/10.1021/la990856l
34 https://doi.org/10.1080/10408390591000884
35 https://doi.org/10.1081/ddc-100101263
36 https://doi.org/10.1111/j.1527-3466.1997.tb00331.x
37 https://doi.org/10.1111/j.1749-6632.1961.tb44987.x
38 https://doi.org/10.1111/j.2042-7158.1975.tb09378.x
39 https://doi.org/10.3109/03639049709150551
40 schema:datePublished 2013-06
41 schema:datePublishedReg 2013-06-01
42 schema:description A solid self emulsifying formulation (S-SEF) has been developed with an intention to improve the dissolution characteristics of poorly water soluble lercanidipine hydrochloride (LH). Suitable components for the formulation of liquid self emulsifying drug delivery systems (SEDDS) were selected after screening various vehicles via solubility studies. Formulations were designed with Gelucire® 44/14 as oil, labrasol as surfactant and transcutol-P as co surfactant. The prepared formulations were evaluated for self emulsifying efficiency and ternary phase diagram was used to designate optimum systems in the emulsifying domain. These systems were further investigated for robustness towards different pH conditions, globule size, thermodynamic stability, surface morphology, cloud point and in vitro drug release. The optimized LH loaded formulation possessed a mean globule size of 142.5 ± 5.37 nm and cloud point of 72 ± 2.66 °C. The liquid SEDDS was transformed into free flowing S-SEF by adsorbing on to an inert carrier, Neusilin US2®. The results revealed no difference in globule size and emulsification characteristics between liquid SEDDS and S-SEF. The solid state characterization studies indicated loss of crystallinity for the drug. Significant improvement in dissolution characteristics of LH for prepared S-SEF was observed compared with pure drug.
43 schema:genre research_article
44 schema:inLanguage en
45 schema:isAccessibleForFree false
46 schema:isPartOf N8a2ff5c873034ad3bb2e69379e307d40
47 Nc99aebe167d5480abcef389aa7789074
48 sg:journal.1044391
49 schema:name A Gelucire 44/14 and labrasol based solid self emulsifying drug delivery system: formulation and evaluation
50 schema:pagination 185-196
51 schema:productId N00da286f203842cbaf1ef39d9e62935f
52 N05c32c6667a140448a1e7ede77edbe03
53 N96d6abbd638a406385b78d26f7be9927
54 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037818326
55 https://doi.org/10.1007/s40005-013-0060-9
56 schema:sdDatePublished 2019-04-10T17:34
57 schema:sdLicense https://scigraph.springernature.com/explorer/license/
58 schema:sdPublisher N449f71c6d19c44fcaf1ddf1da32905d6
59 schema:url http://link.springer.com/10.1007%2Fs40005-013-0060-9
60 sgo:license sg:explorer/license/
61 sgo:sdDataset articles
62 rdf:type schema:ScholarlyArticle
63 N00da286f203842cbaf1ef39d9e62935f schema:name doi
64 schema:value 10.1007/s40005-013-0060-9
65 rdf:type schema:PropertyValue
66 N01c565fac1b6456fac7587a07d5b3ac2 rdf:first sg:person.0725567676.59
67 rdf:rest N1117c8eeec884389807d1a93ad3f8c15
68 N05c32c6667a140448a1e7ede77edbe03 schema:name dimensions_id
69 schema:value pub.1037818326
70 rdf:type schema:PropertyValue
71 N1117c8eeec884389807d1a93ad3f8c15 rdf:first Ne7cc9cba386b4a8bad28017077fe0d9b
72 rdf:rest N2035382cbc494fd3833ad61dfe1eb4ba
73 N2035382cbc494fd3833ad61dfe1eb4ba rdf:first sg:person.01207730101.26
74 rdf:rest rdf:nil
75 N449f71c6d19c44fcaf1ddf1da32905d6 schema:name Springer Nature - SN SciGraph project
76 rdf:type schema:Organization
77 N4945611be30144ee8ebe8d8bf96e60b4 rdf:first sg:person.01314563300.01
78 rdf:rest N01c565fac1b6456fac7587a07d5b3ac2
79 N8a2ff5c873034ad3bb2e69379e307d40 schema:issueNumber 3
80 rdf:type schema:PublicationIssue
81 N96d6abbd638a406385b78d26f7be9927 schema:name readcube_id
82 schema:value b42828c76f00d066bddc82103c3c208be2417c3f1909527d1b212f36865f2e1f
83 rdf:type schema:PropertyValue
84 Nae4100d3e6d6441aaac6232ff3e2dc3b rdf:first sg:person.010136420127.24
85 rdf:rest N4945611be30144ee8ebe8d8bf96e60b4
86 Nc99aebe167d5480abcef389aa7789074 schema:volumeNumber 43
87 rdf:type schema:PublicationVolume
88 Ne7cc9cba386b4a8bad28017077fe0d9b schema:affiliation https://www.grid.ac/institutes/grid.411990.4
89 schema:familyName Ajmeera
90 schema:givenName Ram Kishan
91 rdf:type schema:Person
92 anzsrc-for:03 schema:inDefinedTermSet anzsrc-for:
93 schema:name Chemical Sciences
94 rdf:type schema:DefinedTerm
95 anzsrc-for:0306 schema:inDefinedTermSet anzsrc-for:
96 schema:name Physical Chemistry (incl. Structural)
97 rdf:type schema:DefinedTerm
98 sg:journal.1044391 schema:issn 2093-5552
99 2093-6214
100 schema:name Journal of Pharmaceutical Investigation
101 rdf:type schema:Periodical
102 sg:person.010136420127.24 schema:affiliation https://www.grid.ac/institutes/grid.411990.4
103 schema:familyName Kallakunta
104 schema:givenName Venkata Raman
105 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010136420127.24
106 rdf:type schema:Person
107 sg:person.01207730101.26 schema:affiliation https://www.grid.ac/institutes/grid.411990.4
108 schema:familyName Bandari
109 schema:givenName Suresh
110 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01207730101.26
111 rdf:type schema:Person
112 sg:person.01314563300.01 schema:affiliation https://www.grid.ac/institutes/grid.411990.4
113 schema:familyName Eedara
114 schema:givenName Basanth Babu
115 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01314563300.01
116 rdf:type schema:Person
117 sg:person.0725567676.59 schema:affiliation https://www.grid.ac/institutes/grid.411990.4
118 schema:familyName Jukanti
119 schema:givenName Raju
120 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0725567676.59
121 rdf:type schema:Person
122 sg:pub.10.1007/bf02977782 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011279324
123 https://doi.org/10.1007/bf02977782
124 rdf:type schema:CreativeWork
125 sg:pub.10.1007/s11095-007-9304-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045071125
126 https://doi.org/10.1007/s11095-007-9304-6
127 rdf:type schema:CreativeWork
128 sg:pub.10.1023/a:1018987928936 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034450606
129 https://doi.org/10.1023/a:1018987928936
130 rdf:type schema:CreativeWork
131 sg:pub.10.1208/pt050342 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000740796
132 https://doi.org/10.1208/pt050342
133 rdf:type schema:CreativeWork
134 https://app.dimensions.ai/details/publication/pub.1083391384 schema:CreativeWork
135 https://doi.org/10.1002/jps.2600550409 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037523533
136 rdf:type schema:CreativeWork
137 https://doi.org/10.1002/jps.2600821002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038157945
138 rdf:type schema:CreativeWork
139 https://doi.org/10.1016/0378-5173(90)90381-d schema:sameAs https://app.dimensions.ai/details/publication/pub.1030419691
140 rdf:type schema:CreativeWork
141 https://doi.org/10.1016/0378-5173(94)00222-q schema:sameAs https://app.dimensions.ai/details/publication/pub.1020243805
142 rdf:type schema:CreativeWork
143 https://doi.org/10.1016/j.addr.2007.05.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008039331
144 rdf:type schema:CreativeWork
145 https://doi.org/10.1016/j.biopha.2004.02.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012015777
146 rdf:type schema:CreativeWork
147 https://doi.org/10.1016/j.colsurfb.2009.01.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020299861
148 rdf:type schema:CreativeWork
149 https://doi.org/10.1016/j.ejpb.2005.12.005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032501114
150 rdf:type schema:CreativeWork
151 https://doi.org/10.1016/j.ejpb.2006.10.014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016279393
152 rdf:type schema:CreativeWork
153 https://doi.org/10.1016/j.ejps.2004.08.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052134817
154 rdf:type schema:CreativeWork
155 https://doi.org/10.1016/j.ejps.2008.06.013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040520971
156 rdf:type schema:CreativeWork
157 https://doi.org/10.1016/j.ejps.2009.12.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017607757
158 rdf:type schema:CreativeWork
159 https://doi.org/10.1016/j.ijpharm.2007.12.026 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038515955
160 rdf:type schema:CreativeWork
161 https://doi.org/10.1016/j.ijpharm.2009.07.015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043103882
162 rdf:type schema:CreativeWork
163 https://doi.org/10.1016/j.jconrel.2006.05.010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012699535
164 rdf:type schema:CreativeWork
165 https://doi.org/10.1016/s0024-3205(01)01375-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032375929
166 rdf:type schema:CreativeWork
167 https://doi.org/10.1016/s0168-3659(02)00050-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029061926
168 rdf:type schema:CreativeWork
169 https://doi.org/10.1016/s0168-3659(03)00261-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1052820587
170 rdf:type schema:CreativeWork
171 https://doi.org/10.1016/s0169-409x(00)00103-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022127682
172 rdf:type schema:CreativeWork
173 https://doi.org/10.1016/s0169-409x(00)00129-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006677292
174 rdf:type schema:CreativeWork
175 https://doi.org/10.1016/s0169-409x(96)00494-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037307232
176 rdf:type schema:CreativeWork
177 https://doi.org/10.1016/s0939-6411(00)00087-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013506980
178 rdf:type schema:CreativeWork
179 https://doi.org/10.1016/s0939-6411(03)00142-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026253698
180 rdf:type schema:CreativeWork
181 https://doi.org/10.1021/la000493l schema:sameAs https://app.dimensions.ai/details/publication/pub.1056139367
182 rdf:type schema:CreativeWork
183 https://doi.org/10.1021/la990856l schema:sameAs https://app.dimensions.ai/details/publication/pub.1056171482
184 rdf:type schema:CreativeWork
185 https://doi.org/10.1080/10408390591000884 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034820372
186 rdf:type schema:CreativeWork
187 https://doi.org/10.1081/ddc-100101263 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016583559
188 rdf:type schema:CreativeWork
189 https://doi.org/10.1111/j.1527-3466.1997.tb00331.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1001127991
190 rdf:type schema:CreativeWork
191 https://doi.org/10.1111/j.1749-6632.1961.tb44987.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1046472609
192 rdf:type schema:CreativeWork
193 https://doi.org/10.1111/j.2042-7158.1975.tb09378.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1027829664
194 rdf:type schema:CreativeWork
195 https://doi.org/10.3109/03639049709150551 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007277854
196 rdf:type schema:CreativeWork
197 https://www.grid.ac/institutes/grid.411990.4 schema:alternateName Kakatiya University
198 schema:name Department of Pharmaceutics, St. Peter’s Institute of Pharmaceutical Sciences, Hanamkonda, Vidyanagar, 506001, Warangal, Andhra Pradesh, India
199 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...