HBsAg-negative/anti-HBc-positive patients treated with rituximab: prophylaxis or monitoring to prevent hepatitis B reactivation? View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-04

AUTHORS

Linda Drößler, Clara Lehmann, Karin Töpelt, Dirk Nierhoff, Jörg J. Vehreschild, Jan Rybniker, Michael Hallek, Julia Fischer, Verena Stormberg, Gerd Fätkenheuer, Ulrike Wieland, Norma Jung

ABSTRACT

Rituximab (RTX) has been classified as a drug associated with a high risk for hepatitis B virus (HBV) reactivation in HbsAg-negative/anti-HBc-positive patients. However, data on frequency of HBV reactivation are limited especially for RTX monotherapy. Several new recommendations for screening, monitoring and prophylactic antiviral treatment have been published recently. Here, we report the real-life experience in the management and reactivation rate of HbsAg-negative/anti-HBc-positive patients treated with RTX with or without chemotherapy from a large cohort and discuss our results in the light of updated recommendations. More... »

PAGES

293-300

References to SciGraph publications

Journal

TITLE

Infection

ISSUE

2

VOLUME

47

Author Affiliations

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s15010-019-01271-z

DOI

http://dx.doi.org/10.1007/s15010-019-01271-z

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1111682529

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30689161


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