Influence of a strictly perioperative antibiotic prophylaxis vs a prolonged postoperative prophylaxis on surgical site infections in maxillofacial surgery View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2017-12-18

AUTHORS

Alexander K. Bartella, Sebastian Lemmen, Aida Burnic, Anita Kloss-Brandstätter, Mohammad Kamal, Thomas Breisach, Frank Hölzle, Bernd Lethaus

ABSTRACT

PurposeThe adequate perioperative antibiotic prophylaxis in maxillofacial surgery is still under discussion due to the wide range of hard and soft tissue procedures as well as contaminated, semi-contaminated and clean surgical sides. Perioperative antibiosis is an easy applicable tool that can be used to decrease nosocomial morbidity and mortality by reducing the rate of infections. We compared strictly perioperative antibiosis with an extended postoperative prophylactic antibiosis.Materials and methodsIn this study, 901 consecutive patients, from a tertiary care maxillofacial surgery department were included and distributed into two groups: The first group received peri- and postoperative antibiotic prophylaxis (PP; n = 365) from the day of operation until the fifth day postoperatively. The second group was treated with single shot prophylaxis with intraoperative repetition as needed (SSP; n = 536) only. Furthermore, the patients were grouped according to their main diagnosis and surgical procedure. For comparison, general anamnestic data, cultured bacteria and resistances, number of surgical site infections and duration of hospitalization were compared.ResultsThere were no statistically significant differences in general diseases or extent of surgery between the groups. There was no statistical difference in the surgical site infections between the groups regardless of their diagnosis. There were significant correlations between tracheotomised patients (p < 0.001) as well as patients with a higher BMI (p = 0.009) and the incidence of surgical site infections. Most common cultured bacteria were staphylococci.ConclusionBased on the findings of the study, we believe that a perioperative antibiosis delivers a sufficient prophylaxis for patients undergoing maxillofacial surgery procedures. More... »

PAGES

225-230

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s15010-017-1110-4

DOI

http://dx.doi.org/10.1007/s15010-017-1110-4

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1099710569

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/29250713


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