Therapieziel molekulare Remission in der Praxisroutine View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2018-12

AUTHORS

Hans Tesch, Philipp Jost, Jolanta Dengler, Daniel Mardi, Jens Kisro, Rudolf Weide, Gregor Springer, Deutsche CML-Allianz

ABSTRACT

In Deutschland erkranken nach Angaben des Robert-Koch-Instituts jährlich etwa 1.200 Menschen neu an einer chronischen myeloischen Leukämie (CML). Durch die Einführung von Tyrosinkinaseinhibitoren, die sich gegen das Fusionsprotein BCR-ABL1, eine pathologische Tyrosinkinase mit konstitutiver Aktivität richten, hat sich die Prognose der Betroffenen deutlich gebessert. Für einen Teil der Patienten bietet sich möglicherweise sogar die Chance auf eine andauernde therapiefreie Remission. Wie steht es um die Therapie von CML-Patienten in Deutschland? More... »

PAGES

54-58

Journal

TITLE

InFo Onkologie

ISSUE

8

VOLUME

21

Author Affiliations

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s15004-018-6335-6

DOI

http://dx.doi.org/10.1007/s15004-018-6335-6

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1110507286


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