Ontology type: schema:ScholarlyArticle
2018-08-31
AUTHORSA. Shadi, A. Oujifard
ABSTRACTIn the present report, we focused on the screening of antibacterial, hemolytic and cytotoxic activities of Holothuria parva sea cucumber from the Persian Gulf for potential application in nutraceutical and pharmaceutical products. Ethanol, methanol and aqueous extracts of H. parva were prepared by maceration of milled body wall pieces. Cytotoxicity of extracts was tested using brine shrimp lethality assay. Antibacterial activity of extracts was tested against Vibrio alginolyticus, Vibrio parahaemolyticus, Shigella flexneri Salmonella group D, Escherichia coli and Staphylococcus aureus by serial dilution method. Hemolytic activity of extracts was performed using human erythrocytes. Results showed bacterial inhibition of ethanolic and methanolic extracts against E. coli, V. parahaemolyticus and S. aureus at concentrations higher than 20 µg/ml and minimum bactericidal concentration was observed for ethanolic and methanolic extracts at 500 mg/µl against E. coli. The median lethal concentration for brine shrimp was lowest (61.25 ± 8.53) for methanolic extracts, which shows this extract is more toxic against tested organisms. The methanolic and ethanolic extracts of H. parva showed a high level of hemolytic activity (0.62 ± 0.12 and 0.54 ± 0.9) to tested erythrocytes and were comparable to standard pure saponin, but no such activity was found in aqueous extracts. More... »
PAGES1-8
http://scigraph.springernature.com/pub.10.1007/s13762-018-1956-8
DOIhttp://dx.doi.org/10.1007/s13762-018-1956-8
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1106470062
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0605",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Microbiology",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Biological Sciences",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "Persian Gulf University",
"id": "https://www.grid.ac/institutes/grid.412491.b",
"name": [
"Department of Marine Biotechnology, Faculty of Marine Science and Technology, Persian Gulf University, Bushehr, Iran"
],
"type": "Organization"
},
"familyName": "Shadi",
"givenName": "A.",
"type": "Person"
},
{
"affiliation": {
"alternateName": "Persian Gulf University",
"id": "https://www.grid.ac/institutes/grid.412491.b",
"name": [
"Department of Fisheries, Faculty of Agriculture and Natural Resources, Persian Gulf University, Bushehr, Iran"
],
"type": "Organization"
},
"familyName": "Oujifard",
"givenName": "A.",
"id": "sg:person.01271734701.94",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01271734701.94"
],
"type": "Person"
}
],
"citation": [
{
"id": "https://doi.org/10.3390/md14080147",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1013496424"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/ecam/neh030",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1014013793"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.foodchem.2007.01.016",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1015113142"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.5812/jjm.8708",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1017330649"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00343-016-4334-8",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1020435376",
"https://doi.org/10.1007/s00343-016-4334-8"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.3390/md9101761",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1024041184"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.cbpb.2013.09.002",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1025131354"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.3390/md12084539",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1033368949"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0022-2011(02)00153-2",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1038935860"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0022-2011(02)00153-2",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1038935860"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.3109/13880209.2015.1075047",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1040243779"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.mycmed.2008.01.002",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1040285539"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/jsfa.4108",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1045920901"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/jsfa.4108",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1045920901"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.3923/ijp.2009.228.231",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1046153333"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1128/jcm.39.12.4283-4287.2001",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1046246830"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1073/pnas.0811143106",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1050592447"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1017/s0025315412001889",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1054814946"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1021/np010332x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1056228306"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1021/np010332x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1056228306"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1055/s-2007-971236",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1057503704"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.12980/jclm.2.2014jclm-2014-0056",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1064850558"
],
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1079244074",
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.5812/jjnpp.32422",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1090999685"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.3390/md15100317",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1092242758"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1201/9781420052640",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1109725818"
],
"type": "CreativeWork"
}
],
"datePublished": "2018-08-31",
"datePublishedReg": "2018-08-31",
"description": "In the present report, we focused on the screening of antibacterial, hemolytic and cytotoxic activities of Holothuria parva sea cucumber from the Persian Gulf for potential application in nutraceutical and pharmaceutical products. Ethanol, methanol and aqueous extracts of H. parva were prepared by maceration of milled body wall pieces. Cytotoxicity of extracts was tested using brine shrimp lethality assay. Antibacterial activity of extracts was tested against Vibrio alginolyticus, Vibrio parahaemolyticus, Shigella flexneri Salmonella group D, Escherichia coli and Staphylococcus aureus by serial dilution method. Hemolytic activity of extracts was performed using human erythrocytes. Results showed bacterial inhibition of ethanolic and methanolic extracts against E. coli, V. parahaemolyticus and S. aureus at concentrations higher than 20 \u00b5g/ml and minimum bactericidal concentration was observed for ethanolic and methanolic extracts at 500 mg/\u00b5l against E. coli. The median lethal concentration for brine shrimp was lowest (61.25 \u00b1 8.53) for methanolic extracts, which shows this extract is more toxic against tested organisms. The methanolic and ethanolic extracts of H. parva showed a high level of hemolytic activity (0.62 \u00b1 0.12 and 0.54 \u00b1 0.9) to tested erythrocytes and were comparable to standard pure saponin, but no such activity was found in aqueous extracts.",
"genre": "research_article",
"id": "sg:pub.10.1007/s13762-018-1956-8",
"inLanguage": [
"en"
],
"isAccessibleForFree": false,
"isPartOf": [
{
"id": "sg:journal.1036943",
"issn": [
"1735-1472",
"1735-2630"
],
"name": "International Journal of Environmental Science and Technology",
"type": "Periodical"
}
],
"name": "Antibacterial, cytotoxic and hemolytic activity of Holothuria parva sea cucumber from north Persian Gulf",
"pagination": "1-8",
"productId": [
{
"name": "readcube_id",
"type": "PropertyValue",
"value": [
"84426eb825df07b01d57e0ea9c58d5e1d687f6a8a373adf5499b6f915d571f1f"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1007/s13762-018-1956-8"
]
},
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1106470062"
]
}
],
"sameAs": [
"https://doi.org/10.1007/s13762-018-1956-8",
"https://app.dimensions.ai/details/publication/pub.1106470062"
],
"sdDataset": "articles",
"sdDatePublished": "2019-04-10T13:32",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8659_00000605.jsonl",
"type": "ScholarlyArticle",
"url": "https://link.springer.com/10.1007%2Fs13762-018-1956-8"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s13762-018-1956-8'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s13762-018-1956-8'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s13762-018-1956-8'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s13762-018-1956-8'
This table displays all metadata directly associated to this object as RDF triples.
131 TRIPLES
21 PREDICATES
47 URIs
16 LITERALS
5 BLANK NODES