Evaluation of the flow of cerebrospinal fluid as well as gender and age characteristics in patients with communicating hydrocephalus, using ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2016-12

AUTHORS

Olga Bogomyakova, Yu. Stankevich, N. Mesropyan, L. Shaybman, A. Tulupov

ABSTRACT

To determine the difference in the velocity parameters of cerebrospinal fluid flow in patients with varying severity of communicating hydrocephalus compared to a group of healthy volunteers without hydrodynamic disorders. The study involved 35 subjects with communicating hydrocephalus (25 subjects with Evans index of 0.31; 10 subject with Evans index of 0.46) and 62 healthy volunteers. The mean, volume, and peak flow velocities were determined at the different intracranial levels. Also were made an assessment of gender and age differences. Analysis of the differences between the mean values showed the progressive inhibition of cerebrospinal fluid outflow from the cranial cavity [in moderate communicating hydrocephalus-at 1.5 times (p < 0.05), in severe communicating hydrocephalus at 2-2.5 times (p < 0.01)], depending on the severity of enlargement of the ventricular system and, most likely, related to inhibition of its reabsorption. These changes may explain the clinical symptoms of subjects and serve as diagnostic criteria. Also it was revealed a significant influence of the factor of age on speed characteristics of the cerebrospinal fluid flow (F = 5.3303, p = 0.0003, for mean velocity). More... »

PAGES

495-501

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s13760-016-0608-3

DOI

http://dx.doi.org/10.1007/s13760-016-0608-3

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1025379448

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/26848963


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