A new peptide nucleotide acid biosensor for electrochemical detection of single nucleotide polymorphism in duplex DNA via triplex structure formation View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2013-12

AUTHORS

Ezat Hamidi-Asl, Jahan Bakhsh Raoof, Reza Ojani, Seyed Mahdi Golabi, Mohammad Saeid Hejazi

ABSTRACT

In this paper, we report a new PNA biosensor for electrochemical detection of point mutation or single nucleotide polymorphism (SNP) in p53 gene corresponding oligonucleotide based on PNA/ds-DNA triplex formation following hybridization of PNA probe with double-stranded DNA (ds-DNA) sample without denaturing the ds-DNA into single-stranded DNA (ss-DNA). As p53 gene is mutated in many human tumors, this research is useful for cancer therapy and genomic study. In this approach, methylene blue (MB) is used for electrochemical signal generation and the interaction between MB and oligonucleotides is studied by differential pulse voltammety (DPV). Probe-modified electrode is prepared by self-assembled monolayer (SAM) formation of thiolated PNA molecules on the surface of Au electrode. A significant increase in the reduction signal of MB following hybridization of the probe with the complementary double-stranded oligonucleotide (ds-oligonucleotide) confirms the function of the biosensor. The selectivity of the PNA sensor is investigated by non-complementary ds-oligonucleotides and the results support the ability of the sensor to detect single-base mismatch directly on ds-oligonucleotide. The influence of probe and ds-DNA concentrations on the effective discrimination against complementary sequence and point mutation is studied and the concentration of 10−6 M is selected as appropriate concentration. Diagnostic performance of the biosensor is described and the detection limit is found to be 4.15 × 10−12 M. More... »

PAGES

1075-1083

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s13738-013-0254-0

DOI

http://dx.doi.org/10.1007/s13738-013-0254-0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1013666247


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0306", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Physical Chemistry (incl. Structural)", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/03", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Chemical Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "University of Mazandaran", 
          "id": "https://www.grid.ac/institutes/grid.411622.2", 
          "name": [
            "Eletroanalytical Chemistry Research Laboratory, Department of Analytical Chemistry, Faculty of Chemistry, University of Mazandaran, Babolsar, Iran"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hamidi-Asl", 
        "givenName": "Ezat", 
        "id": "sg:person.01224603471.71", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01224603471.71"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Mazandaran", 
          "id": "https://www.grid.ac/institutes/grid.411622.2", 
          "name": [
            "Eletroanalytical Chemistry Research Laboratory, Department of Analytical Chemistry, Faculty of Chemistry, University of Mazandaran, Babolsar, Iran"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Raoof", 
        "givenName": "Jahan Bakhsh", 
        "id": "sg:person.013640435726.13", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013640435726.13"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Mazandaran", 
          "id": "https://www.grid.ac/institutes/grid.411622.2", 
          "name": [
            "Eletroanalytical Chemistry Research Laboratory, Department of Analytical Chemistry, Faculty of Chemistry, University of Mazandaran, Babolsar, Iran"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ojani", 
        "givenName": "Reza", 
        "id": "sg:person.013730623371.81", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013730623371.81"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Eletroanalytical Chemistry Research Laboratory, Department of Analytical Chemistry, Faculty of Chemistry, Tabriz University, Tabriz, Iran"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Golabi", 
        "givenName": "Seyed Mahdi", 
        "id": "sg:person.0641027031.21", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0641027031.21"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Tabriz University of Medical Sciences", 
          "id": "https://www.grid.ac/institutes/grid.412888.f", 
          "name": [
            "Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran", 
            "Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hejazi", 
        "givenName": "Mohammad Saeid", 
        "id": "sg:person.0775060577.00", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0775060577.00"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/j.talanta.2006.08.010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001373833"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.snb.2011.03.049", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008202223"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf03246208", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009188929", 
          "https://doi.org/10.1007/bf03246208"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0003-2670(02)00470-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010927374"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.semcdb.2009.01.015", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013539548"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.electacta.2010.11.092", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015735213"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0927-7757(00)00537-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018934957"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.snb.2013.02.026", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018968772"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.aca.2006.04.067", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019258869"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0169-409x(02)00182-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020346716"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0169-409x(02)00182-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020346716"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf03254292", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022634722", 
          "https://doi.org/10.1007/bf03254292"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-1-4614-0935-9_7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025792222", 
          "https://doi.org/10.1007/978-1-4614-0935-9_7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00216-012-6476-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026741300", 
          "https://doi.org/10.1007/s00216-012-6476-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf03246017", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027001134", 
          "https://doi.org/10.1007/bf03246017"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bios.2009.06.012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027102752"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jcis.2008.02.010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027252296"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf03245868", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028411391", 
          "https://doi.org/10.1007/bf03245868"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bbrc.2005.03.149", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028515863"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bios.2004.08.002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034908263"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cjoc.201180427", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035511723"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bios.2008.01.021", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036397179"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf03246202", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036733052", 
          "https://doi.org/10.1007/bf03246202"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ja905068s", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039162789"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ja905068s", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039162789"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1529/biophysj.104.051656", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040177344"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/elan.200603746", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040655236"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bioelechem.2010.02.004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041405528"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bbrc.2005.03.152", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043131799"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf03246086", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045259061", 
          "https://doi.org/10.1007/bf03246086"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bioelechem.2009.09.004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046148830"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bios.2008.05.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046846444"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bios.2009.08.032", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047513003"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.anngen.2004.07.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049111571"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ja0041324", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049180992"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ja0041324", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049180992"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1146/annurev.bi.64.070195.000433", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050414976"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ac1024528", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055000991"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ac1024528", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055000991"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi00105a015", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055161069"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ja060069s", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055841429"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ja060069s", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055841429"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2013-12", 
    "datePublishedReg": "2013-12-01", 
    "description": "In this paper, we report a new PNA biosensor for electrochemical detection of point mutation or single nucleotide polymorphism (SNP) in p53 gene corresponding oligonucleotide based on PNA/ds-DNA triplex formation following hybridization of PNA probe with double-stranded DNA (ds-DNA) sample without denaturing the ds-DNA into single-stranded DNA (ss-DNA). As p53 gene is mutated in many human tumors, this research is useful for cancer therapy and genomic study. In this approach, methylene blue (MB) is used for electrochemical signal generation and the interaction between MB and oligonucleotides is studied by differential pulse voltammety (DPV). Probe-modified electrode is prepared by self-assembled monolayer (SAM) formation of thiolated PNA molecules on the surface of Au electrode. A significant increase in the reduction signal of MB following hybridization of the probe with the complementary double-stranded oligonucleotide (ds-oligonucleotide) confirms the function of the biosensor. The selectivity of the PNA sensor is investigated by non-complementary ds-oligonucleotides and the results support the ability of the sensor to detect single-base mismatch directly on ds-oligonucleotide. The influence of probe and ds-DNA concentrations on the effective discrimination against complementary sequence and point mutation is studied and the concentration of 10\u22126 M is selected as appropriate concentration. Diagnostic performance of the biosensor is described and the detection limit is found to be 4.15 \u00d7 10\u221212 M.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s13738-013-0254-0", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1037017", 
        "issn": [
          "1735-207X", 
          "1735-2428"
        ], 
        "name": "Journal of the Iranian Chemical Society", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "6", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "10"
      }
    ], 
    "name": "A new peptide nucleotide acid biosensor for electrochemical detection of single nucleotide polymorphism in duplex DNA via triplex structure formation", 
    "pagination": "1075-1083", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "411a46ddce20f76488d99513657de57986c51379410e3883bff1fe794d7a0fac"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s13738-013-0254-0"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1013666247"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s13738-013-0254-0", 
      "https://app.dimensions.ai/details/publication/pub.1013666247"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T14:12", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8660_00000521.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007%2Fs13738-013-0254-0"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s13738-013-0254-0'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s13738-013-0254-0'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s13738-013-0254-0'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s13738-013-0254-0'


 

This table displays all metadata directly associated to this object as RDF triples.

214 TRIPLES      21 PREDICATES      64 URIs      19 LITERALS      7 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s13738-013-0254-0 schema:about anzsrc-for:03
2 anzsrc-for:0306
3 schema:author N3025b6b7a6384cdba506222385dc0891
4 schema:citation sg:pub.10.1007/978-1-4614-0935-9_7
5 sg:pub.10.1007/bf03245868
6 sg:pub.10.1007/bf03246017
7 sg:pub.10.1007/bf03246086
8 sg:pub.10.1007/bf03246202
9 sg:pub.10.1007/bf03246208
10 sg:pub.10.1007/bf03254292
11 sg:pub.10.1007/s00216-012-6476-7
12 https://doi.org/10.1002/cjoc.201180427
13 https://doi.org/10.1002/elan.200603746
14 https://doi.org/10.1016/j.aca.2006.04.067
15 https://doi.org/10.1016/j.anngen.2004.07.001
16 https://doi.org/10.1016/j.bbrc.2005.03.149
17 https://doi.org/10.1016/j.bbrc.2005.03.152
18 https://doi.org/10.1016/j.bioelechem.2009.09.004
19 https://doi.org/10.1016/j.bioelechem.2010.02.004
20 https://doi.org/10.1016/j.bios.2004.08.002
21 https://doi.org/10.1016/j.bios.2008.01.021
22 https://doi.org/10.1016/j.bios.2008.05.008
23 https://doi.org/10.1016/j.bios.2009.06.012
24 https://doi.org/10.1016/j.bios.2009.08.032
25 https://doi.org/10.1016/j.electacta.2010.11.092
26 https://doi.org/10.1016/j.jcis.2008.02.010
27 https://doi.org/10.1016/j.semcdb.2009.01.015
28 https://doi.org/10.1016/j.snb.2011.03.049
29 https://doi.org/10.1016/j.snb.2013.02.026
30 https://doi.org/10.1016/j.talanta.2006.08.010
31 https://doi.org/10.1016/s0003-2670(02)00470-1
32 https://doi.org/10.1016/s0169-409x(02)00182-5
33 https://doi.org/10.1016/s0927-7757(00)00537-9
34 https://doi.org/10.1021/ac1024528
35 https://doi.org/10.1021/bi00105a015
36 https://doi.org/10.1021/ja0041324
37 https://doi.org/10.1021/ja060069s
38 https://doi.org/10.1021/ja905068s
39 https://doi.org/10.1146/annurev.bi.64.070195.000433
40 https://doi.org/10.1529/biophysj.104.051656
41 schema:datePublished 2013-12
42 schema:datePublishedReg 2013-12-01
43 schema:description In this paper, we report a new PNA biosensor for electrochemical detection of point mutation or single nucleotide polymorphism (SNP) in p53 gene corresponding oligonucleotide based on PNA/ds-DNA triplex formation following hybridization of PNA probe with double-stranded DNA (ds-DNA) sample without denaturing the ds-DNA into single-stranded DNA (ss-DNA). As p53 gene is mutated in many human tumors, this research is useful for cancer therapy and genomic study. In this approach, methylene blue (MB) is used for electrochemical signal generation and the interaction between MB and oligonucleotides is studied by differential pulse voltammety (DPV). Probe-modified electrode is prepared by self-assembled monolayer (SAM) formation of thiolated PNA molecules on the surface of Au electrode. A significant increase in the reduction signal of MB following hybridization of the probe with the complementary double-stranded oligonucleotide (ds-oligonucleotide) confirms the function of the biosensor. The selectivity of the PNA sensor is investigated by non-complementary ds-oligonucleotides and the results support the ability of the sensor to detect single-base mismatch directly on ds-oligonucleotide. The influence of probe and ds-DNA concentrations on the effective discrimination against complementary sequence and point mutation is studied and the concentration of 10−6 M is selected as appropriate concentration. Diagnostic performance of the biosensor is described and the detection limit is found to be 4.15 × 10−12 M.
44 schema:genre research_article
45 schema:inLanguage en
46 schema:isAccessibleForFree false
47 schema:isPartOf N16913980ec1146dbb55982fc4fef8902
48 N2653ce32ede64608a4017957f385c9a7
49 sg:journal.1037017
50 schema:name A new peptide nucleotide acid biosensor for electrochemical detection of single nucleotide polymorphism in duplex DNA via triplex structure formation
51 schema:pagination 1075-1083
52 schema:productId N505ad9f982604bd9bd7fcb942dc1dc4b
53 Nc16566b660e440149672a5d9c8293c1e
54 Ne2a152108d9c4d66b6479012872ed305
55 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013666247
56 https://doi.org/10.1007/s13738-013-0254-0
57 schema:sdDatePublished 2019-04-10T14:12
58 schema:sdLicense https://scigraph.springernature.com/explorer/license/
59 schema:sdPublisher N2c2baee20d724c819d04a8f050d63fc4
60 schema:url http://link.springer.com/10.1007%2Fs13738-013-0254-0
61 sgo:license sg:explorer/license/
62 sgo:sdDataset articles
63 rdf:type schema:ScholarlyArticle
64 N16913980ec1146dbb55982fc4fef8902 schema:volumeNumber 10
65 rdf:type schema:PublicationVolume
66 N2653ce32ede64608a4017957f385c9a7 schema:issueNumber 6
67 rdf:type schema:PublicationIssue
68 N26e9fceb44414981917e22fd5e731f29 rdf:first sg:person.0641027031.21
69 rdf:rest Nda9a076a3c8a4f74a79e1fb3d44b0b41
70 N2c2baee20d724c819d04a8f050d63fc4 schema:name Springer Nature - SN SciGraph project
71 rdf:type schema:Organization
72 N3025b6b7a6384cdba506222385dc0891 rdf:first sg:person.01224603471.71
73 rdf:rest Ndddbf9d25d70424d997d16741d6c132b
74 N505ad9f982604bd9bd7fcb942dc1dc4b schema:name readcube_id
75 schema:value 411a46ddce20f76488d99513657de57986c51379410e3883bff1fe794d7a0fac
76 rdf:type schema:PropertyValue
77 N7fc62b9a77a54cbe84e26d0a9b890931 schema:name Eletroanalytical Chemistry Research Laboratory, Department of Analytical Chemistry, Faculty of Chemistry, Tabriz University, Tabriz, Iran
78 rdf:type schema:Organization
79 Nc16566b660e440149672a5d9c8293c1e schema:name doi
80 schema:value 10.1007/s13738-013-0254-0
81 rdf:type schema:PropertyValue
82 Nc3d5cb1985c5485881bfde8af2864181 rdf:first sg:person.013730623371.81
83 rdf:rest N26e9fceb44414981917e22fd5e731f29
84 Nda9a076a3c8a4f74a79e1fb3d44b0b41 rdf:first sg:person.0775060577.00
85 rdf:rest rdf:nil
86 Ndddbf9d25d70424d997d16741d6c132b rdf:first sg:person.013640435726.13
87 rdf:rest Nc3d5cb1985c5485881bfde8af2864181
88 Ne2a152108d9c4d66b6479012872ed305 schema:name dimensions_id
89 schema:value pub.1013666247
90 rdf:type schema:PropertyValue
91 anzsrc-for:03 schema:inDefinedTermSet anzsrc-for:
92 schema:name Chemical Sciences
93 rdf:type schema:DefinedTerm
94 anzsrc-for:0306 schema:inDefinedTermSet anzsrc-for:
95 schema:name Physical Chemistry (incl. Structural)
96 rdf:type schema:DefinedTerm
97 sg:journal.1037017 schema:issn 1735-207X
98 1735-2428
99 schema:name Journal of the Iranian Chemical Society
100 rdf:type schema:Periodical
101 sg:person.01224603471.71 schema:affiliation https://www.grid.ac/institutes/grid.411622.2
102 schema:familyName Hamidi-Asl
103 schema:givenName Ezat
104 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01224603471.71
105 rdf:type schema:Person
106 sg:person.013640435726.13 schema:affiliation https://www.grid.ac/institutes/grid.411622.2
107 schema:familyName Raoof
108 schema:givenName Jahan Bakhsh
109 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013640435726.13
110 rdf:type schema:Person
111 sg:person.013730623371.81 schema:affiliation https://www.grid.ac/institutes/grid.411622.2
112 schema:familyName Ojani
113 schema:givenName Reza
114 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013730623371.81
115 rdf:type schema:Person
116 sg:person.0641027031.21 schema:affiliation N7fc62b9a77a54cbe84e26d0a9b890931
117 schema:familyName Golabi
118 schema:givenName Seyed Mahdi
119 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0641027031.21
120 rdf:type schema:Person
121 sg:person.0775060577.00 schema:affiliation https://www.grid.ac/institutes/grid.412888.f
122 schema:familyName Hejazi
123 schema:givenName Mohammad Saeid
124 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0775060577.00
125 rdf:type schema:Person
126 sg:pub.10.1007/978-1-4614-0935-9_7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025792222
127 https://doi.org/10.1007/978-1-4614-0935-9_7
128 rdf:type schema:CreativeWork
129 sg:pub.10.1007/bf03245868 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028411391
130 https://doi.org/10.1007/bf03245868
131 rdf:type schema:CreativeWork
132 sg:pub.10.1007/bf03246017 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027001134
133 https://doi.org/10.1007/bf03246017
134 rdf:type schema:CreativeWork
135 sg:pub.10.1007/bf03246086 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045259061
136 https://doi.org/10.1007/bf03246086
137 rdf:type schema:CreativeWork
138 sg:pub.10.1007/bf03246202 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036733052
139 https://doi.org/10.1007/bf03246202
140 rdf:type schema:CreativeWork
141 sg:pub.10.1007/bf03246208 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009188929
142 https://doi.org/10.1007/bf03246208
143 rdf:type schema:CreativeWork
144 sg:pub.10.1007/bf03254292 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022634722
145 https://doi.org/10.1007/bf03254292
146 rdf:type schema:CreativeWork
147 sg:pub.10.1007/s00216-012-6476-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026741300
148 https://doi.org/10.1007/s00216-012-6476-7
149 rdf:type schema:CreativeWork
150 https://doi.org/10.1002/cjoc.201180427 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035511723
151 rdf:type schema:CreativeWork
152 https://doi.org/10.1002/elan.200603746 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040655236
153 rdf:type schema:CreativeWork
154 https://doi.org/10.1016/j.aca.2006.04.067 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019258869
155 rdf:type schema:CreativeWork
156 https://doi.org/10.1016/j.anngen.2004.07.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049111571
157 rdf:type schema:CreativeWork
158 https://doi.org/10.1016/j.bbrc.2005.03.149 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028515863
159 rdf:type schema:CreativeWork
160 https://doi.org/10.1016/j.bbrc.2005.03.152 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043131799
161 rdf:type schema:CreativeWork
162 https://doi.org/10.1016/j.bioelechem.2009.09.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046148830
163 rdf:type schema:CreativeWork
164 https://doi.org/10.1016/j.bioelechem.2010.02.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041405528
165 rdf:type schema:CreativeWork
166 https://doi.org/10.1016/j.bios.2004.08.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034908263
167 rdf:type schema:CreativeWork
168 https://doi.org/10.1016/j.bios.2008.01.021 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036397179
169 rdf:type schema:CreativeWork
170 https://doi.org/10.1016/j.bios.2008.05.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046846444
171 rdf:type schema:CreativeWork
172 https://doi.org/10.1016/j.bios.2009.06.012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027102752
173 rdf:type schema:CreativeWork
174 https://doi.org/10.1016/j.bios.2009.08.032 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047513003
175 rdf:type schema:CreativeWork
176 https://doi.org/10.1016/j.electacta.2010.11.092 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015735213
177 rdf:type schema:CreativeWork
178 https://doi.org/10.1016/j.jcis.2008.02.010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027252296
179 rdf:type schema:CreativeWork
180 https://doi.org/10.1016/j.semcdb.2009.01.015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013539548
181 rdf:type schema:CreativeWork
182 https://doi.org/10.1016/j.snb.2011.03.049 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008202223
183 rdf:type schema:CreativeWork
184 https://doi.org/10.1016/j.snb.2013.02.026 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018968772
185 rdf:type schema:CreativeWork
186 https://doi.org/10.1016/j.talanta.2006.08.010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001373833
187 rdf:type schema:CreativeWork
188 https://doi.org/10.1016/s0003-2670(02)00470-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010927374
189 rdf:type schema:CreativeWork
190 https://doi.org/10.1016/s0169-409x(02)00182-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020346716
191 rdf:type schema:CreativeWork
192 https://doi.org/10.1016/s0927-7757(00)00537-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018934957
193 rdf:type schema:CreativeWork
194 https://doi.org/10.1021/ac1024528 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055000991
195 rdf:type schema:CreativeWork
196 https://doi.org/10.1021/bi00105a015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055161069
197 rdf:type schema:CreativeWork
198 https://doi.org/10.1021/ja0041324 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049180992
199 rdf:type schema:CreativeWork
200 https://doi.org/10.1021/ja060069s schema:sameAs https://app.dimensions.ai/details/publication/pub.1055841429
201 rdf:type schema:CreativeWork
202 https://doi.org/10.1021/ja905068s schema:sameAs https://app.dimensions.ai/details/publication/pub.1039162789
203 rdf:type schema:CreativeWork
204 https://doi.org/10.1146/annurev.bi.64.070195.000433 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050414976
205 rdf:type schema:CreativeWork
206 https://doi.org/10.1529/biophysj.104.051656 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040177344
207 rdf:type schema:CreativeWork
208 https://www.grid.ac/institutes/grid.411622.2 schema:alternateName University of Mazandaran
209 schema:name Eletroanalytical Chemistry Research Laboratory, Department of Analytical Chemistry, Faculty of Chemistry, University of Mazandaran, Babolsar, Iran
210 rdf:type schema:Organization
211 https://www.grid.ac/institutes/grid.412888.f schema:alternateName Tabriz University of Medical Sciences
212 schema:name Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
213 Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
214 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...