Scleroderma renal crisis in a newly diagnosed mixed connective tissue disease resulting in dialysis-dependent chronic kidney disease despite angiotensin-converting enzyme ... View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2013-05

AUTHORS

Muhammad Abdul Mabood Khalil, Nadia Iftikhar, Syed Ather Hussain, Jackson Tan

ABSTRACT

Mixed connective tissue disease (MCTD) is a rheumatic disease with a combination of multiple connective tissue disorders, which includes dermatomyositis or polymyositis, systemic sclerosis, systemic lupus erythematosus, rheumatoid arthritis and Sjögren's syndrome. It affects various organs of the body, which includes the lungs, heart, kidneys, joints, muscles and the haematological system. Here, we report a case of MCTD consisting of scleroderma, Sjögren's syndrome and polymyositis complicated by scleroderma renal crisis (SRC) but with negative anti-nuclear antibody (ANA), anti-Scl 70 and anti-centromere antibodies. The patient was started on captopril for the treatment of SRC but developed chronic kidney disease despite adequate blood pressure control with angiotensin-converting enzyme inhibitor (ACEi). More... »

PAGES

41-45

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s13730-012-0036-z

DOI

http://dx.doi.org/10.1007/s13730-012-0036-z

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1047890007

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/28509217


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