A case of intracranial hypotension caused by docetaxel treatment for metastatic breast cancer View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2014-10-22

AUTHORS

Hiroshi Nakagomi, Kazushige Furuya, Yuko Nakayama, Kazunori Takahashi, Masahiro Maruyama, Atushi Takano, Hidemitu Sugai, Masao Hada, Yoshiaki Miyasaka, Akitoshi Saito

ABSTRACT

Intracranial hypotension (IH) is noted to be a cause of postural headache. Progress in diagnostic imaging modalities, such as magnetic resonance imaging (MRI) had contributed to the diagnosis for IH (Thomke et al., Nervenarzt 70:909–915, 1999), revealing the presences of IH in various situations. A 48-year-old female with left breast cancer underwent the breast conserving surgery in April 2003, and mastectomy for ipsilateral breast cancer in December 2007. Multiple lung metastases were found in both lungs over the next year. After receiving an EC regimen for five cycles, the patient’s lung metastases were improved. Subsequently, she received docetaxel according to a weekly regimen. Following the administration of docetaxel for 10 months, the patient suffered from dyspnea, headache, vertigo, and diplopia, and was diagnosed with IH based on the MRI findings. Her symptoms improved with bed rest, hydration and the administration of dexamethasone. In this case, the patient developed IH under conditions of severe fluid retention as a side effect of docetaxel. We herein report this rare case of IH related to cancer therapy. More... »

PAGES

184-187

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s13691-014-0196-0

DOI

http://dx.doi.org/10.1007/s13691-014-0196-0

DIMENSIONS

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