Evaluation of effectiveness of palliative radiotherapy for bone metastases: a prospective cohort study View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2018-12

AUTHORS

Joanne M. van der Velden, Yvette M. van der Linden, Anne L. Versteeg, Jorrit-Jan Verlaan, A. Sophie Gerlich, Bart J. Pielkenrood, Nicolien Kasperts, Helena M. Verkooijen

ABSTRACT

Objective: Radiotherapy is the standard local treatment for patients with painful bone metastases, but effectiveness has primarily been evaluated in trial populations. The aim of this study was to study pain response to palliative radiotherapy in a prospective cohort of unselected patients with bone metastases. Methods: Patients with painful bone metastases referred to the UMC Utrecht for radiotherapy and enrolled in the PRESENT cohort were included in this study. For all patients, pain response to radiotherapy was assessed, and responders were defined as patients with a complete or partial pain response. Patients with stable pain scores, pain increase, or undetermined response were regarded non-responders. Pain scores obtained at baseline and after 2, 4, 6, 8, and 12 weeks following radiotherapy were obtained. Pain response rates of the total treated population, as well as response rates of the assessable patients, were calculated. To measure the percentage of the remaining time spent with pain relief, the net pain relief (NPR) was calculated by dividing the period of pain relief by the period of survival. Results: Of the 432 patients enrolled in this study, 262 patients (61%) experienced a complete or partial response. In the 390 assessable patients, this percentage was 67%. Median time to response was 4 weeks (range 1-15 weeks), and the NPR was 64%. Conclusion: Compared to randomized trial populations, palliative radiotherapy in our unselected patients with bone metastases showed similar pain response rates (61%), with a reasonable duration of this effect. More... »

PAGES

325-333

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s13566-018-0363-6

DOI

http://dx.doi.org/10.1007/s13566-018-0363-6

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1109804364

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30595809


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "University Medical Center Utrecht", 
          "id": "https://www.grid.ac/institutes/grid.7692.a", 
          "name": [
            "Department of Radiation Oncology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands"
          ], 
          "type": "Organization"
        }, 
        "familyName": "van der Velden", 
        "givenName": "Joanne M.", 
        "id": "sg:person.01341533126.29", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01341533126.29"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Leiden University Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.10419.3d", 
          "name": [
            "Department of Radiation Oncology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands"
          ], 
          "type": "Organization"
        }, 
        "familyName": "van der Linden", 
        "givenName": "Yvette M.", 
        "id": "sg:person.01030615010.33", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01030615010.33"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University Medical Center Utrecht", 
          "id": "https://www.grid.ac/institutes/grid.7692.a", 
          "name": [
            "Department of Orthopedic Surgery, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Versteeg", 
        "givenName": "Anne L.", 
        "id": "sg:person.0767566320.70", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0767566320.70"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University Medical Center Utrecht", 
          "id": "https://www.grid.ac/institutes/grid.7692.a", 
          "name": [
            "Department of Orthopedic Surgery, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Verlaan", 
        "givenName": "Jorrit-Jan", 
        "id": "sg:person.01323471636.71", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01323471636.71"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University Medical Center Utrecht", 
          "id": "https://www.grid.ac/institutes/grid.7692.a", 
          "name": [
            "Department of Radiation Oncology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sophie Gerlich", 
        "givenName": "A.", 
        "id": "sg:person.015526332421.59", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015526332421.59"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University Medical Center Utrecht", 
          "id": "https://www.grid.ac/institutes/grid.7692.a", 
          "name": [
            "Department of Radiation Oncology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pielkenrood", 
        "givenName": "Bart J.", 
        "id": "sg:person.010670445420.04", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010670445420.04"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University Medical Center Utrecht", 
          "id": "https://www.grid.ac/institutes/grid.7692.a", 
          "name": [
            "Department of Radiation Oncology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kasperts", 
        "givenName": "Nicolien", 
        "id": "sg:person.01043072523.79", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01043072523.79"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University Medical Center Utrecht", 
          "id": "https://www.grid.ac/institutes/grid.7692.a", 
          "name": [
            "Department of Radiation Oncology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands", 
            "Department of Clinical Epidemiology, Julius Center for Health Sciences and Primary Care, Universiteitsweg 100, 3584 CG, Utrecht, The Netherlands"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Verkooijen", 
        "givenName": "Helena M.", 
        "id": "sg:person.01313710671.91", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01313710671.91"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/s10198-013-0502-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002728488", 
          "https://doi.org/10.1007/s10198-013-0502-3"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10198-013-0502-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002728488", 
          "https://doi.org/10.1007/s10198-013-0502-3"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ejca.2005.06.022", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005098077"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00520-011-1144-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006527808", 
          "https://doi.org/10.1007/s00520-011-1144-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1470-2045(11)70384-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007215007"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ijrobp.2016.03.032", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016151419"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1470-2045(08)70041-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017909316"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/1097-0142(19860701)58:1<29::aid-cncr2820580107>3.0.co;2-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018287865"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1634/theoncologist.9-5-571", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018998577"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ijrobp.2011.02.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022134713"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/ede.0000000000000435", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024662636"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/ede.0000000000000435", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024662636"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/ede.0000000000000435", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024662636"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0167-8140(99)00110-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024748534"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ijrobp.2012.05.028", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026799636"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cncr.27616", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032026969"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(07)61602-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036200026"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ijrobp.2015.06.024", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038894886"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0167-8140(01)00390-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040386382"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cncr.20756", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042006843"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/jnci/djv324", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045299061"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jama.297.11.1233", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049222902"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.clon.2007.09.009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049871467"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.radonc.2008.05.018", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052168336"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ijrobp.2003.10.006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052244641"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/bmj.c1066", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062804795"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/bmj.c1066", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062804795"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3310/hta9380", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1071139846"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082642225", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ijrobp.2017.07.029", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1090937694"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.radonc.2018.01.003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1100776054"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.radonc.2018.01.003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1100776054"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2018-12", 
    "datePublishedReg": "2018-12-01", 
    "description": "Objective: Radiotherapy is the standard local treatment for patients with painful bone metastases, but effectiveness has primarily been evaluated in trial populations. The aim of this study was to study pain response to palliative radiotherapy in a prospective cohort of unselected patients with bone metastases.\nMethods: Patients with painful bone metastases referred to the UMC Utrecht for radiotherapy and enrolled in the PRESENT cohort were included in this study. For all patients, pain response to radiotherapy was assessed, and responders were defined as patients with a complete or partial pain response. Patients with stable pain scores, pain increase, or undetermined response were regarded non-responders. Pain scores obtained at baseline and after 2, 4, 6, 8, and 12\u00a0weeks following radiotherapy were obtained. Pain response rates of the total treated population, as well as response rates of the assessable patients, were calculated. To measure the percentage of the remaining time spent with pain relief, the net pain relief (NPR) was calculated by dividing the period of pain relief by the period of survival.\nResults: Of the 432 patients enrolled in this study, 262 patients (61%) experienced a complete or partial response. In the 390 assessable patients, this percentage was 67%. Median time to response was 4\u00a0weeks (range 1-15\u00a0weeks), and the NPR was 64%.\nConclusion: Compared to randomized trial populations, palliative radiotherapy in our unselected patients with bone metastases showed similar pain response rates (61%), with a reasonable duration of this effect.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s13566-018-0363-6", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1047354", 
        "issn": [
          "1948-7894", 
          "1948-7908"
        ], 
        "name": "Journal of Radiation Oncology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "4", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "7"
      }
    ], 
    "name": "Evaluation of effectiveness of palliative radiotherapy for bone metastases: a prospective cohort study", 
    "pagination": "325-333", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "0c10fce5177103e754e8f43985d611bd0bc8ab62e503798dfb761e046b1e1621"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30595809"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101590774"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s13566-018-0363-6"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1109804364"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s13566-018-0363-6", 
      "https://app.dimensions.ai/details/publication/pub.1109804364"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T08:30", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000309_0000000309/records_106259_00000000.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://link.springer.com/10.1007%2Fs13566-018-0363-6"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s13566-018-0363-6'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s13566-018-0363-6'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s13566-018-0363-6'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s13566-018-0363-6'


 

This table displays all metadata directly associated to this object as RDF triples.

205 TRIPLES      21 PREDICATES      56 URIs      21 LITERALS      9 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s13566-018-0363-6 schema:about anzsrc-for:11
2 anzsrc-for:1103
3 schema:author N83df1d6e00c7416d91fb5b345945a47e
4 schema:citation sg:pub.10.1007/s00520-011-1144-6
5 sg:pub.10.1007/s10198-013-0502-3
6 https://app.dimensions.ai/details/publication/pub.1082642225
7 https://doi.org/10.1001/jama.297.11.1233
8 https://doi.org/10.1002/1097-0142(19860701)58:1<29::aid-cncr2820580107>3.0.co;2-2
9 https://doi.org/10.1002/cncr.20756
10 https://doi.org/10.1002/cncr.27616
11 https://doi.org/10.1016/j.clon.2007.09.009
12 https://doi.org/10.1016/j.ejca.2005.06.022
13 https://doi.org/10.1016/j.ijrobp.2003.10.006
14 https://doi.org/10.1016/j.ijrobp.2011.02.008
15 https://doi.org/10.1016/j.ijrobp.2012.05.028
16 https://doi.org/10.1016/j.ijrobp.2015.06.024
17 https://doi.org/10.1016/j.ijrobp.2016.03.032
18 https://doi.org/10.1016/j.ijrobp.2017.07.029
19 https://doi.org/10.1016/j.radonc.2008.05.018
20 https://doi.org/10.1016/j.radonc.2018.01.003
21 https://doi.org/10.1016/s0140-6736(07)61602-x
22 https://doi.org/10.1016/s0167-8140(01)00390-5
23 https://doi.org/10.1016/s0167-8140(99)00110-3
24 https://doi.org/10.1016/s1470-2045(08)70041-x
25 https://doi.org/10.1016/s1470-2045(11)70384-9
26 https://doi.org/10.1093/jnci/djv324
27 https://doi.org/10.1097/ede.0000000000000435
28 https://doi.org/10.1136/bmj.c1066
29 https://doi.org/10.1634/theoncologist.9-5-571
30 https://doi.org/10.3310/hta9380
31 schema:datePublished 2018-12
32 schema:datePublishedReg 2018-12-01
33 schema:description Objective: Radiotherapy is the standard local treatment for patients with painful bone metastases, but effectiveness has primarily been evaluated in trial populations. The aim of this study was to study pain response to palliative radiotherapy in a prospective cohort of unselected patients with bone metastases. Methods: Patients with painful bone metastases referred to the UMC Utrecht for radiotherapy and enrolled in the PRESENT cohort were included in this study. For all patients, pain response to radiotherapy was assessed, and responders were defined as patients with a complete or partial pain response. Patients with stable pain scores, pain increase, or undetermined response were regarded non-responders. Pain scores obtained at baseline and after 2, 4, 6, 8, and 12 weeks following radiotherapy were obtained. Pain response rates of the total treated population, as well as response rates of the assessable patients, were calculated. To measure the percentage of the remaining time spent with pain relief, the net pain relief (NPR) was calculated by dividing the period of pain relief by the period of survival. Results: Of the 432 patients enrolled in this study, 262 patients (61%) experienced a complete or partial response. In the 390 assessable patients, this percentage was 67%. Median time to response was 4 weeks (range 1-15 weeks), and the NPR was 64%. Conclusion: Compared to randomized trial populations, palliative radiotherapy in our unselected patients with bone metastases showed similar pain response rates (61%), with a reasonable duration of this effect.
34 schema:genre research_article
35 schema:inLanguage en
36 schema:isAccessibleForFree false
37 schema:isPartOf N96344eaca02340cc9f5a8d0a020d1af6
38 Naed8bab00a6b48f5afee2fed3b51bca9
39 sg:journal.1047354
40 schema:name Evaluation of effectiveness of palliative radiotherapy for bone metastases: a prospective cohort study
41 schema:pagination 325-333
42 schema:productId N013a429aeffe47879c458e4bc562329b
43 N34c58b70f38d4bba9aad32b53f1aba7b
44 N3535e3aeefbb456f914afcf8561fc3c5
45 N3a8fae5509034e1eb227482d979c6df0
46 Ne2080b525f9446519b043e7989b5c61d
47 schema:sameAs https://app.dimensions.ai/details/publication/pub.1109804364
48 https://doi.org/10.1007/s13566-018-0363-6
49 schema:sdDatePublished 2019-04-11T08:30
50 schema:sdLicense https://scigraph.springernature.com/explorer/license/
51 schema:sdPublisher N97757c7baa8d40669b306e5ece628538
52 schema:url https://link.springer.com/10.1007%2Fs13566-018-0363-6
53 sgo:license sg:explorer/license/
54 sgo:sdDataset articles
55 rdf:type schema:ScholarlyArticle
56 N013a429aeffe47879c458e4bc562329b schema:name doi
57 schema:value 10.1007/s13566-018-0363-6
58 rdf:type schema:PropertyValue
59 N273dbfaafde64a7fa48d98fc7892cf4c rdf:first sg:person.010670445420.04
60 rdf:rest N3663c63f24a1443587ad4db92bb494d8
61 N34c58b70f38d4bba9aad32b53f1aba7b schema:name readcube_id
62 schema:value 0c10fce5177103e754e8f43985d611bd0bc8ab62e503798dfb761e046b1e1621
63 rdf:type schema:PropertyValue
64 N3535e3aeefbb456f914afcf8561fc3c5 schema:name dimensions_id
65 schema:value pub.1109804364
66 rdf:type schema:PropertyValue
67 N356d88d226d8430aa39ada9866d2b55e rdf:first sg:person.01323471636.71
68 rdf:rest Ne2af5297535446edbb61ed2df71a3648
69 N3663c63f24a1443587ad4db92bb494d8 rdf:first sg:person.01043072523.79
70 rdf:rest N7a1e7823ef1a472896dd63ec3b86c7cb
71 N3a8fae5509034e1eb227482d979c6df0 schema:name pubmed_id
72 schema:value 30595809
73 rdf:type schema:PropertyValue
74 N7a1e7823ef1a472896dd63ec3b86c7cb rdf:first sg:person.01313710671.91
75 rdf:rest rdf:nil
76 N83df1d6e00c7416d91fb5b345945a47e rdf:first sg:person.01341533126.29
77 rdf:rest N9ca5f7211458446ab818c56191fc18fd
78 N96344eaca02340cc9f5a8d0a020d1af6 schema:issueNumber 4
79 rdf:type schema:PublicationIssue
80 N97757c7baa8d40669b306e5ece628538 schema:name Springer Nature - SN SciGraph project
81 rdf:type schema:Organization
82 N9ca5f7211458446ab818c56191fc18fd rdf:first sg:person.01030615010.33
83 rdf:rest Nf20b58ce24194614b21b55e24f95bfa9
84 Naed8bab00a6b48f5afee2fed3b51bca9 schema:volumeNumber 7
85 rdf:type schema:PublicationVolume
86 Ne2080b525f9446519b043e7989b5c61d schema:name nlm_unique_id
87 schema:value 101590774
88 rdf:type schema:PropertyValue
89 Ne2af5297535446edbb61ed2df71a3648 rdf:first sg:person.015526332421.59
90 rdf:rest N273dbfaafde64a7fa48d98fc7892cf4c
91 Nf20b58ce24194614b21b55e24f95bfa9 rdf:first sg:person.0767566320.70
92 rdf:rest N356d88d226d8430aa39ada9866d2b55e
93 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
94 schema:name Medical and Health Sciences
95 rdf:type schema:DefinedTerm
96 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
97 schema:name Clinical Sciences
98 rdf:type schema:DefinedTerm
99 sg:journal.1047354 schema:issn 1948-7894
100 1948-7908
101 schema:name Journal of Radiation Oncology
102 rdf:type schema:Periodical
103 sg:person.01030615010.33 schema:affiliation https://www.grid.ac/institutes/grid.10419.3d
104 schema:familyName van der Linden
105 schema:givenName Yvette M.
106 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01030615010.33
107 rdf:type schema:Person
108 sg:person.01043072523.79 schema:affiliation https://www.grid.ac/institutes/grid.7692.a
109 schema:familyName Kasperts
110 schema:givenName Nicolien
111 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01043072523.79
112 rdf:type schema:Person
113 sg:person.010670445420.04 schema:affiliation https://www.grid.ac/institutes/grid.7692.a
114 schema:familyName Pielkenrood
115 schema:givenName Bart J.
116 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010670445420.04
117 rdf:type schema:Person
118 sg:person.01313710671.91 schema:affiliation https://www.grid.ac/institutes/grid.7692.a
119 schema:familyName Verkooijen
120 schema:givenName Helena M.
121 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01313710671.91
122 rdf:type schema:Person
123 sg:person.01323471636.71 schema:affiliation https://www.grid.ac/institutes/grid.7692.a
124 schema:familyName Verlaan
125 schema:givenName Jorrit-Jan
126 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01323471636.71
127 rdf:type schema:Person
128 sg:person.01341533126.29 schema:affiliation https://www.grid.ac/institutes/grid.7692.a
129 schema:familyName van der Velden
130 schema:givenName Joanne M.
131 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01341533126.29
132 rdf:type schema:Person
133 sg:person.015526332421.59 schema:affiliation https://www.grid.ac/institutes/grid.7692.a
134 schema:familyName Sophie Gerlich
135 schema:givenName A.
136 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015526332421.59
137 rdf:type schema:Person
138 sg:person.0767566320.70 schema:affiliation https://www.grid.ac/institutes/grid.7692.a
139 schema:familyName Versteeg
140 schema:givenName Anne L.
141 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0767566320.70
142 rdf:type schema:Person
143 sg:pub.10.1007/s00520-011-1144-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006527808
144 https://doi.org/10.1007/s00520-011-1144-6
145 rdf:type schema:CreativeWork
146 sg:pub.10.1007/s10198-013-0502-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002728488
147 https://doi.org/10.1007/s10198-013-0502-3
148 rdf:type schema:CreativeWork
149 https://app.dimensions.ai/details/publication/pub.1082642225 schema:CreativeWork
150 https://doi.org/10.1001/jama.297.11.1233 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049222902
151 rdf:type schema:CreativeWork
152 https://doi.org/10.1002/1097-0142(19860701)58:1<29::aid-cncr2820580107>3.0.co;2-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018287865
153 rdf:type schema:CreativeWork
154 https://doi.org/10.1002/cncr.20756 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042006843
155 rdf:type schema:CreativeWork
156 https://doi.org/10.1002/cncr.27616 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032026969
157 rdf:type schema:CreativeWork
158 https://doi.org/10.1016/j.clon.2007.09.009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049871467
159 rdf:type schema:CreativeWork
160 https://doi.org/10.1016/j.ejca.2005.06.022 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005098077
161 rdf:type schema:CreativeWork
162 https://doi.org/10.1016/j.ijrobp.2003.10.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052244641
163 rdf:type schema:CreativeWork
164 https://doi.org/10.1016/j.ijrobp.2011.02.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022134713
165 rdf:type schema:CreativeWork
166 https://doi.org/10.1016/j.ijrobp.2012.05.028 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026799636
167 rdf:type schema:CreativeWork
168 https://doi.org/10.1016/j.ijrobp.2015.06.024 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038894886
169 rdf:type schema:CreativeWork
170 https://doi.org/10.1016/j.ijrobp.2016.03.032 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016151419
171 rdf:type schema:CreativeWork
172 https://doi.org/10.1016/j.ijrobp.2017.07.029 schema:sameAs https://app.dimensions.ai/details/publication/pub.1090937694
173 rdf:type schema:CreativeWork
174 https://doi.org/10.1016/j.radonc.2008.05.018 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052168336
175 rdf:type schema:CreativeWork
176 https://doi.org/10.1016/j.radonc.2018.01.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1100776054
177 rdf:type schema:CreativeWork
178 https://doi.org/10.1016/s0140-6736(07)61602-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1036200026
179 rdf:type schema:CreativeWork
180 https://doi.org/10.1016/s0167-8140(01)00390-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040386382
181 rdf:type schema:CreativeWork
182 https://doi.org/10.1016/s0167-8140(99)00110-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024748534
183 rdf:type schema:CreativeWork
184 https://doi.org/10.1016/s1470-2045(08)70041-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1017909316
185 rdf:type schema:CreativeWork
186 https://doi.org/10.1016/s1470-2045(11)70384-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007215007
187 rdf:type schema:CreativeWork
188 https://doi.org/10.1093/jnci/djv324 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045299061
189 rdf:type schema:CreativeWork
190 https://doi.org/10.1097/ede.0000000000000435 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024662636
191 rdf:type schema:CreativeWork
192 https://doi.org/10.1136/bmj.c1066 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062804795
193 rdf:type schema:CreativeWork
194 https://doi.org/10.1634/theoncologist.9-5-571 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018998577
195 rdf:type schema:CreativeWork
196 https://doi.org/10.3310/hta9380 schema:sameAs https://app.dimensions.ai/details/publication/pub.1071139846
197 rdf:type schema:CreativeWork
198 https://www.grid.ac/institutes/grid.10419.3d schema:alternateName Leiden University Medical Center
199 schema:name Department of Radiation Oncology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands
200 rdf:type schema:Organization
201 https://www.grid.ac/institutes/grid.7692.a schema:alternateName University Medical Center Utrecht
202 schema:name Department of Clinical Epidemiology, Julius Center for Health Sciences and Primary Care, Universiteitsweg 100, 3584 CG, Utrecht, The Netherlands
203 Department of Orthopedic Surgery, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands
204 Department of Radiation Oncology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands
205 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...