Prevalence and risk factors of cognitive dysfunction in patients with type 2 diabetes mellitus receiving care in a reference hospital ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2017-06-21

AUTHORS

Zainab I. Abba, Yannick Mboue-Djieka, Yacouba N. Mapoure, Cyrille Nkouonlack, Henry N. Luma, Simeon-Pierre Choukem

ABSTRACT

Diabetes mellitus has been associated with cognitive impairment but this has not been well investigated in sub-Saharan Africa. The aim of this study was to determine the prevalence and risk factors of cognitive dysfunction in patients with type 2 diabetes and to assess its influence on medication adherence. We carried out a cross-sectional study over a period of 4 months at the outpatient diabetes and endocrinology clinic of the Douala General Hospital. Consecutive patients with type 2 diabetes attending the clinic underwent cognitive assessment using the Mini Mental State Exam (MMSE). The patient Health Questionnaire-9 (PHQ-9) was used to rule out the confounding effect of depression, and the Morisky score was used to assess medication adherence. Data were analyzed using SPSS version 20 for Windows. Of the 223 participants (54.3% females) with a mean age of 56 ± 9.5 years, 33 (14.8%) had cognitive dysfunction (12.6, 1.8, and 0.4% having mild, moderate, and severe cognitive dysfunction, respectively). Level of education ≤7 years (OR = 5.314, 95% CI 2.443–11.561, p < 0.001) was the only factor significantly associated with cognitive dysfunction. No significant association was found between cognitive dysfunction and treatment adherence. In conclusion, one out of seven of our patients with type 2 diabetes have cognitive dysfunction, which is strongly associated with low level of education and does not affect treatment adherence and glycemic control. Our results suggest that screening for cognitive dysfunction in our patients should focus on patients with a low level of education. More... »

PAGES

158-164

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s13410-017-0565-2

DOI

http://dx.doi.org/10.1007/s13410-017-0565-2

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1086103594


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188 grid-institutes:grid.512673.4 schema:alternateName Health and Human Development (2HD) Research Network, P.O. Box 4856, Douala, Cameroon
189 schema:name Health and Human Development (2HD) Research Network, P.O. Box 4856, Douala, Cameroon
190 rdf:type schema:Organization
191 grid-institutes:grid.513958.3 schema:alternateName Department of Internal Medicine, Douala General Hospital, Douala, Cameroon
192 schema:name Department of Internal Medicine and Pediatrics, Faculty of Health Sciences, University of Buea, Buea, Cameroon
193 Department of Internal Medicine, Douala General Hospital, Douala, Cameroon
194 Faculty of Medicine and Pharmaceutical Sciences, University of Douala, Douala, Cameroon
195 Health and Human Development (2HD) Research Network, P.O. Box 4856, Douala, Cameroon
196 rdf:type schema:Organization
 




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