Co-infusion of insulin-secreting adipose tissue-derived mesenchymal stem cells and hematopoietic stem cells: novel approach to management of type 1 diabetes ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2016-12

AUTHORS

U. G. Thakkar, H. L. Trivedi, A. V. Vanikar, S. D. Dave

ABSTRACT

Stem cell therapy (SCT) has promising results in regeneration of injured tissues/cells as well as correcting immune dysregulation. We present our experience of co-infusion of human adipose tissue-derived insulin-secreting mesenchymal stem cells (IS-AD-MSC) along with bone marrow-derived hematopoietic stem cells (BM-HSC) in type 1 diabetes mellitus (T1DM). This was an institutional review board-approved prospective non-randomized open-labeled clinical trial after informed consent of 20 patients (15 males and 5 females) with T1DM for SCT, with mean disease duration of 9 ± 5.51 years. Their mean age and weight were 19.95 ± 8.35 years and 49.9 ± 14 kg, respectively. Our study includes T1DM with positive for glutamic acid decarboxylase (GAD) antibody and history of diabetic ketoacidosis (DKA). Generated IS-AD-MSC and BM-HSC were infused via femoral catheterization under local anesthesia into portal + thymic circulation and subcutaneous tissue with conditioning of injection rabbit anti-thymocyte globulin and Bortezomib. Patients were monitored for blood sugar, serum C-peptide, GAD antibodies, and glycosylated hemoglobin (Hb1Ac) at three monthly intervals post-therapy. Mean SC quantum infused 99.45 ± 22.5 mL, with mean 2.38 ± 0.78 × 104 ISC/μL, mean CD34+ 0.57 %, and mean CD45-/90+ and CD45-/73+ were 47.22 and 24.66 %, respectively. Generated ISCs expressed transcription factors ISL-1, PAX-6, and IPF-1. Variable and sustained improvement in mean FBS, PPBS, HbA1c, and serum C-peptide was noted over a mean follow-up of 43.94 ± 19.8 months with mean reduction of GAD antibody from 525.15 to 120.15 IU/mL. Mean insulin requirement decreased from 60.89 to 39.76 IU/day. There was absence of DKA after SCT. No untoward effect/morbidity/mortality was recorded from SCT. Co-infusion of IS-AD-MSC with BM-HSC offers a safe and viable therapy for T1DM. More... »

PAGES

426-432

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s13410-015-0409-x

DOI

http://dx.doi.org/10.1007/s13410-015-0409-x

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1019535392


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Institute of Transplantation Sciences", 
          "id": "https://www.grid.ac/institutes/grid.418780.2", 
          "name": [
            "Department of Regenerative Medicine and Stem Cell Therapy, G.R. Doshi and K.M. Mehta Institute of Kidney Diseases & Research Centre (IKDRC) - Dr. H.L. Trivedi Institute of Transplantation Sciences (ITS), Ahmedabad, Gujarat, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Thakkar", 
        "givenName": "U. G.", 
        "id": "sg:person.01272455414.58", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01272455414.58"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute of Transplantation Sciences", 
          "id": "https://www.grid.ac/institutes/grid.418780.2", 
          "name": [
            "Department of Regenerative Medicine and Stem Cell Therapy, G.R. Doshi and K.M. Mehta Institute of Kidney Diseases & Research Centre (IKDRC) - Dr. H.L. Trivedi Institute of Transplantation Sciences (ITS), Ahmedabad, Gujarat, India", 
            "Department of Nephrology and Transplantation Medicine, G.R. Doshi and K.M. Mehta Institute of Kidney Diseases & Research Centre (IKDRC) - Dr. H.L. Trivedi Institute of Transplantation Sciences (ITS), Ahmedabad, Gujarat, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Trivedi", 
        "givenName": "H. L.", 
        "id": "sg:person.013407021177.25", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013407021177.25"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute of Transplantation Sciences", 
          "id": "https://www.grid.ac/institutes/grid.418780.2", 
          "name": [
            "Department of Regenerative Medicine and Stem Cell Therapy, G.R. Doshi and K.M. Mehta Institute of Kidney Diseases & Research Centre (IKDRC) - Dr. H.L. Trivedi Institute of Transplantation Sciences (ITS), Ahmedabad, Gujarat, India", 
            "Department of Pathology, Laboratory Medicine, Transfusion Services and Immunohematology, G.R. Doshi and K.M. Mehta Institute of Kidney Diseases & Research Centre (IKDRC) - Dr. H.L. Trivedi Institute of Transplantation Sciences (ITS), Ahmedabad, Gujarat, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Vanikar", 
        "givenName": "A. V.", 
        "id": "sg:person.07510564264.28", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07510564264.28"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute of Transplantation Sciences", 
          "id": "https://www.grid.ac/institutes/grid.418780.2", 
          "name": [
            "Department of Regenerative Medicine and Stem Cell Therapy, G.R. Doshi and K.M. Mehta Institute of Kidney Diseases & Research Centre (IKDRC) - Dr. H.L. Trivedi Institute of Transplantation Sciences (ITS), Ahmedabad, Gujarat, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Dave", 
        "givenName": "S. D.", 
        "id": "sg:person.0615164514.55", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0615164514.55"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1053/jlts.2001.0070918", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001591967"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejm200007273430401", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002510707"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.97.14.7999", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011463469"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2337/diabetes.50.3.521", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012128163"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2337/db09-0749", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012894970"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.122210699", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014659778"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4061/2010/582382", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015546536"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/blood-2007-02-069716", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017439048"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1046/j.1365-2362.2003.01190.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018369372"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1634/stemcells.2007-0267", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019370245"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10047-009-0455-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019570359", 
          "https://doi.org/10.1007/s10047-009-0455-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10047-009-0455-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019570359", 
          "https://doi.org/10.1007/s10047-009-0455-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10047-009-0455-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019570359", 
          "https://doi.org/10.1007/s10047-009-0455-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2337/db08-0180", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020957011"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.0608249103", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027271675"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cytogfr.2009.10.002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027524533"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejm199306103282306", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028507830"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.0936260100", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028623918"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2337/diabetes.49.2.157", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029357815"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jama.297.14.1568", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033958493"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/73128", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034700136", 
          "https://doi.org/10.1038/73128"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(03)14526-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036070591"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.transproceed.2008.03.113", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039552579"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1098/rstb.2001.0846", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043930396"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bbrc.2006.01.072", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046550882"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3109/08916930903305641", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047357503"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/(sici)1520-7560(199905/06)15:3<205::aid-dmrr29>3.0.co;2-o", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052578338"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1055/s-2007-985154", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1057513407"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/scd.2007.0266", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059309781"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1058866", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062444457"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077322658", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077417313", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2016-12", 
    "datePublishedReg": "2016-12-01", 
    "description": "Stem cell therapy (SCT) has promising results in regeneration of injured tissues/cells as well as correcting immune dysregulation. We present our experience of co-infusion of human adipose tissue-derived insulin-secreting mesenchymal stem cells (IS-AD-MSC) along with bone marrow-derived hematopoietic stem cells (BM-HSC) in type 1 diabetes mellitus (T1DM). This was an institutional review board-approved prospective non-randomized open-labeled clinical trial after informed consent of 20 patients (15 males and 5 females) with T1DM for SCT, with mean disease duration of 9 \u00b1 5.51 years. Their mean age and weight were 19.95 \u00b1 8.35 years and 49.9 \u00b1 14 kg, respectively. Our study includes T1DM with positive for glutamic acid decarboxylase (GAD) antibody and history of diabetic ketoacidosis (DKA). Generated IS-AD-MSC and BM-HSC were infused via femoral catheterization under local anesthesia into portal + thymic circulation and subcutaneous tissue with conditioning of injection rabbit anti-thymocyte globulin and Bortezomib. Patients were monitored for blood sugar, serum C-peptide, GAD antibodies, and glycosylated hemoglobin (Hb1Ac) at three monthly intervals post-therapy. Mean SC quantum infused 99.45 \u00b1 22.5 mL, with mean 2.38 \u00b1 0.78 \u00d7 104 ISC/\u03bcL, mean CD34+ 0.57 %, and mean CD45-/90+ and CD45-/73+ were 47.22 and 24.66 %, respectively. Generated ISCs expressed transcription factors ISL-1, PAX-6, and IPF-1. Variable and sustained improvement in mean FBS, PPBS, HbA1c, and serum C-peptide was noted over a mean follow-up of 43.94 \u00b1 19.8 months with mean reduction of GAD antibody from 525.15 to 120.15 IU/mL. Mean insulin requirement decreased from 60.89 to 39.76 IU/day. There was absence of DKA after SCT. No untoward effect/morbidity/mortality was recorded from SCT. Co-infusion of IS-AD-MSC with BM-HSC offers a safe and viable therapy for T1DM.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s13410-015-0409-x", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1037614", 
        "issn": [
          "0973-3930", 
          "1998-3832"
        ], 
        "name": "International Journal of Diabetes in Developing Countries", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "4", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "36"
      }
    ], 
    "name": "Co-infusion of insulin-secreting adipose tissue-derived mesenchymal stem cells and hematopoietic stem cells: novel approach to management of type 1 diabetes mellitus", 
    "pagination": "426-432", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "5d1442d87d5bfce79e1b05f6db6b47c82730dee4ee47236cf8219a300be89ca5"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s13410-015-0409-x"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1019535392"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s13410-015-0409-x", 
      "https://app.dimensions.ai/details/publication/pub.1019535392"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T00:18", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8695_00000521.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007%2Fs13410-015-0409-x"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s13410-015-0409-x'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s13410-015-0409-x'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s13410-015-0409-x'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s13410-015-0409-x'


 

This table displays all metadata directly associated to this object as RDF triples.

174 TRIPLES      21 PREDICATES      57 URIs      19 LITERALS      7 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s13410-015-0409-x schema:about anzsrc-for:11
2 anzsrc-for:1103
3 schema:author N33c39b59e62c43c08c5dcd70b3601932
4 schema:citation sg:pub.10.1007/s10047-009-0455-6
5 sg:pub.10.1038/73128
6 https://app.dimensions.ai/details/publication/pub.1077322658
7 https://app.dimensions.ai/details/publication/pub.1077417313
8 https://doi.org/10.1001/jama.297.14.1568
9 https://doi.org/10.1002/(sici)1520-7560(199905/06)15:3<205::aid-dmrr29>3.0.co;2-o
10 https://doi.org/10.1016/j.bbrc.2006.01.072
11 https://doi.org/10.1016/j.cytogfr.2009.10.002
12 https://doi.org/10.1016/j.transproceed.2008.03.113
13 https://doi.org/10.1016/s0140-6736(03)14526-6
14 https://doi.org/10.1046/j.1365-2362.2003.01190.x
15 https://doi.org/10.1053/jlts.2001.0070918
16 https://doi.org/10.1055/s-2007-985154
17 https://doi.org/10.1056/nejm199306103282306
18 https://doi.org/10.1056/nejm200007273430401
19 https://doi.org/10.1073/pnas.0608249103
20 https://doi.org/10.1073/pnas.0936260100
21 https://doi.org/10.1073/pnas.122210699
22 https://doi.org/10.1073/pnas.97.14.7999
23 https://doi.org/10.1089/scd.2007.0266
24 https://doi.org/10.1098/rstb.2001.0846
25 https://doi.org/10.1126/science.1058866
26 https://doi.org/10.1182/blood-2007-02-069716
27 https://doi.org/10.1634/stemcells.2007-0267
28 https://doi.org/10.2337/db08-0180
29 https://doi.org/10.2337/db09-0749
30 https://doi.org/10.2337/diabetes.49.2.157
31 https://doi.org/10.2337/diabetes.50.3.521
32 https://doi.org/10.3109/08916930903305641
33 https://doi.org/10.4061/2010/582382
34 schema:datePublished 2016-12
35 schema:datePublishedReg 2016-12-01
36 schema:description Stem cell therapy (SCT) has promising results in regeneration of injured tissues/cells as well as correcting immune dysregulation. We present our experience of co-infusion of human adipose tissue-derived insulin-secreting mesenchymal stem cells (IS-AD-MSC) along with bone marrow-derived hematopoietic stem cells (BM-HSC) in type 1 diabetes mellitus (T1DM). This was an institutional review board-approved prospective non-randomized open-labeled clinical trial after informed consent of 20 patients (15 males and 5 females) with T1DM for SCT, with mean disease duration of 9 ± 5.51 years. Their mean age and weight were 19.95 ± 8.35 years and 49.9 ± 14 kg, respectively. Our study includes T1DM with positive for glutamic acid decarboxylase (GAD) antibody and history of diabetic ketoacidosis (DKA). Generated IS-AD-MSC and BM-HSC were infused via femoral catheterization under local anesthesia into portal + thymic circulation and subcutaneous tissue with conditioning of injection rabbit anti-thymocyte globulin and Bortezomib. Patients were monitored for blood sugar, serum C-peptide, GAD antibodies, and glycosylated hemoglobin (Hb1Ac) at three monthly intervals post-therapy. Mean SC quantum infused 99.45 ± 22.5 mL, with mean 2.38 ± 0.78 × 104 ISC/μL, mean CD34+ 0.57 %, and mean CD45-/90+ and CD45-/73+ were 47.22 and 24.66 %, respectively. Generated ISCs expressed transcription factors ISL-1, PAX-6, and IPF-1. Variable and sustained improvement in mean FBS, PPBS, HbA1c, and serum C-peptide was noted over a mean follow-up of 43.94 ± 19.8 months with mean reduction of GAD antibody from 525.15 to 120.15 IU/mL. Mean insulin requirement decreased from 60.89 to 39.76 IU/day. There was absence of DKA after SCT. No untoward effect/morbidity/mortality was recorded from SCT. Co-infusion of IS-AD-MSC with BM-HSC offers a safe and viable therapy for T1DM.
37 schema:genre research_article
38 schema:inLanguage en
39 schema:isAccessibleForFree false
40 schema:isPartOf N03f767f307b44a079c5757a357935fb3
41 N510a862ab882449aa68df14961b9bfbc
42 sg:journal.1037614
43 schema:name Co-infusion of insulin-secreting adipose tissue-derived mesenchymal stem cells and hematopoietic stem cells: novel approach to management of type 1 diabetes mellitus
44 schema:pagination 426-432
45 schema:productId N002f35a8ac894d228971ae34f7cc4473
46 N8b2c5af90a014aa8b38f3721f1dd4bb6
47 Nea25209788f348c584e5503cc2ce2d7b
48 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019535392
49 https://doi.org/10.1007/s13410-015-0409-x
50 schema:sdDatePublished 2019-04-11T00:18
51 schema:sdLicense https://scigraph.springernature.com/explorer/license/
52 schema:sdPublisher N29251abdc83740f4800e96d20afcaa1f
53 schema:url http://link.springer.com/10.1007%2Fs13410-015-0409-x
54 sgo:license sg:explorer/license/
55 sgo:sdDataset articles
56 rdf:type schema:ScholarlyArticle
57 N002f35a8ac894d228971ae34f7cc4473 schema:name readcube_id
58 schema:value 5d1442d87d5bfce79e1b05f6db6b47c82730dee4ee47236cf8219a300be89ca5
59 rdf:type schema:PropertyValue
60 N03f767f307b44a079c5757a357935fb3 schema:issueNumber 4
61 rdf:type schema:PublicationIssue
62 N13a934f51ef04b588e68a5d6a5d0785e rdf:first sg:person.07510564264.28
63 rdf:rest Nc5f18bb990f745b9a12ce44fd85cc135
64 N29251abdc83740f4800e96d20afcaa1f schema:name Springer Nature - SN SciGraph project
65 rdf:type schema:Organization
66 N33c39b59e62c43c08c5dcd70b3601932 rdf:first sg:person.01272455414.58
67 rdf:rest Ndcff0b2382924b8b8ab0266a9ad3d7e8
68 N510a862ab882449aa68df14961b9bfbc schema:volumeNumber 36
69 rdf:type schema:PublicationVolume
70 N8b2c5af90a014aa8b38f3721f1dd4bb6 schema:name dimensions_id
71 schema:value pub.1019535392
72 rdf:type schema:PropertyValue
73 Nc5f18bb990f745b9a12ce44fd85cc135 rdf:first sg:person.0615164514.55
74 rdf:rest rdf:nil
75 Ndcff0b2382924b8b8ab0266a9ad3d7e8 rdf:first sg:person.013407021177.25
76 rdf:rest N13a934f51ef04b588e68a5d6a5d0785e
77 Nea25209788f348c584e5503cc2ce2d7b schema:name doi
78 schema:value 10.1007/s13410-015-0409-x
79 rdf:type schema:PropertyValue
80 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
81 schema:name Medical and Health Sciences
82 rdf:type schema:DefinedTerm
83 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
84 schema:name Clinical Sciences
85 rdf:type schema:DefinedTerm
86 sg:journal.1037614 schema:issn 0973-3930
87 1998-3832
88 schema:name International Journal of Diabetes in Developing Countries
89 rdf:type schema:Periodical
90 sg:person.01272455414.58 schema:affiliation https://www.grid.ac/institutes/grid.418780.2
91 schema:familyName Thakkar
92 schema:givenName U. G.
93 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01272455414.58
94 rdf:type schema:Person
95 sg:person.013407021177.25 schema:affiliation https://www.grid.ac/institutes/grid.418780.2
96 schema:familyName Trivedi
97 schema:givenName H. L.
98 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013407021177.25
99 rdf:type schema:Person
100 sg:person.0615164514.55 schema:affiliation https://www.grid.ac/institutes/grid.418780.2
101 schema:familyName Dave
102 schema:givenName S. D.
103 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0615164514.55
104 rdf:type schema:Person
105 sg:person.07510564264.28 schema:affiliation https://www.grid.ac/institutes/grid.418780.2
106 schema:familyName Vanikar
107 schema:givenName A. V.
108 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07510564264.28
109 rdf:type schema:Person
110 sg:pub.10.1007/s10047-009-0455-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019570359
111 https://doi.org/10.1007/s10047-009-0455-6
112 rdf:type schema:CreativeWork
113 sg:pub.10.1038/73128 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034700136
114 https://doi.org/10.1038/73128
115 rdf:type schema:CreativeWork
116 https://app.dimensions.ai/details/publication/pub.1077322658 schema:CreativeWork
117 https://app.dimensions.ai/details/publication/pub.1077417313 schema:CreativeWork
118 https://doi.org/10.1001/jama.297.14.1568 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033958493
119 rdf:type schema:CreativeWork
120 https://doi.org/10.1002/(sici)1520-7560(199905/06)15:3<205::aid-dmrr29>3.0.co;2-o schema:sameAs https://app.dimensions.ai/details/publication/pub.1052578338
121 rdf:type schema:CreativeWork
122 https://doi.org/10.1016/j.bbrc.2006.01.072 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046550882
123 rdf:type schema:CreativeWork
124 https://doi.org/10.1016/j.cytogfr.2009.10.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027524533
125 rdf:type schema:CreativeWork
126 https://doi.org/10.1016/j.transproceed.2008.03.113 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039552579
127 rdf:type schema:CreativeWork
128 https://doi.org/10.1016/s0140-6736(03)14526-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036070591
129 rdf:type schema:CreativeWork
130 https://doi.org/10.1046/j.1365-2362.2003.01190.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1018369372
131 rdf:type schema:CreativeWork
132 https://doi.org/10.1053/jlts.2001.0070918 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001591967
133 rdf:type schema:CreativeWork
134 https://doi.org/10.1055/s-2007-985154 schema:sameAs https://app.dimensions.ai/details/publication/pub.1057513407
135 rdf:type schema:CreativeWork
136 https://doi.org/10.1056/nejm199306103282306 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028507830
137 rdf:type schema:CreativeWork
138 https://doi.org/10.1056/nejm200007273430401 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002510707
139 rdf:type schema:CreativeWork
140 https://doi.org/10.1073/pnas.0608249103 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027271675
141 rdf:type schema:CreativeWork
142 https://doi.org/10.1073/pnas.0936260100 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028623918
143 rdf:type schema:CreativeWork
144 https://doi.org/10.1073/pnas.122210699 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014659778
145 rdf:type schema:CreativeWork
146 https://doi.org/10.1073/pnas.97.14.7999 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011463469
147 rdf:type schema:CreativeWork
148 https://doi.org/10.1089/scd.2007.0266 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059309781
149 rdf:type schema:CreativeWork
150 https://doi.org/10.1098/rstb.2001.0846 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043930396
151 rdf:type schema:CreativeWork
152 https://doi.org/10.1126/science.1058866 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062444457
153 rdf:type schema:CreativeWork
154 https://doi.org/10.1182/blood-2007-02-069716 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017439048
155 rdf:type schema:CreativeWork
156 https://doi.org/10.1634/stemcells.2007-0267 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019370245
157 rdf:type schema:CreativeWork
158 https://doi.org/10.2337/db08-0180 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020957011
159 rdf:type schema:CreativeWork
160 https://doi.org/10.2337/db09-0749 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012894970
161 rdf:type schema:CreativeWork
162 https://doi.org/10.2337/diabetes.49.2.157 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029357815
163 rdf:type schema:CreativeWork
164 https://doi.org/10.2337/diabetes.50.3.521 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012128163
165 rdf:type schema:CreativeWork
166 https://doi.org/10.3109/08916930903305641 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047357503
167 rdf:type schema:CreativeWork
168 https://doi.org/10.4061/2010/582382 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015546536
169 rdf:type schema:CreativeWork
170 https://www.grid.ac/institutes/grid.418780.2 schema:alternateName Institute of Transplantation Sciences
171 schema:name Department of Nephrology and Transplantation Medicine, G.R. Doshi and K.M. Mehta Institute of Kidney Diseases & Research Centre (IKDRC) - Dr. H.L. Trivedi Institute of Transplantation Sciences (ITS), Ahmedabad, Gujarat, India
172 Department of Pathology, Laboratory Medicine, Transfusion Services and Immunohematology, G.R. Doshi and K.M. Mehta Institute of Kidney Diseases & Research Centre (IKDRC) - Dr. H.L. Trivedi Institute of Transplantation Sciences (ITS), Ahmedabad, Gujarat, India
173 Department of Regenerative Medicine and Stem Cell Therapy, G.R. Doshi and K.M. Mehta Institute of Kidney Diseases & Research Centre (IKDRC) - Dr. H.L. Trivedi Institute of Transplantation Sciences (ITS), Ahmedabad, Gujarat, India
174 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...