Vitamin D is not associated with HIV-associated neurocognitive disorder in Rakai, Uganda View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-01-22

AUTHORS

Deanna Saylor, Gertrude Nakigozi, Carlos A. Pardo, Alice Kisakye, Anupama Kumar, Noeline Nakasujja, Kevin R. Robertson, Ronald H. Gray, Maria J. Wawer, Ned Sacktor

ABSTRACT

We investigated whether vitamin D is associated with HIV-associated neurocognitive disorder (HAND). HIV-infected (HIV+) antiretroviral therapy (ART)-naïve adults in rural Uganda underwent a neurocognitive battery for determination of HAND stage at baseline and after 2 years. Baseline serum 25-hydroxyvitamin D (25OH-D) and serum and cerebrospinal fluids (CSF) vitamin D-binding protein (VDBP) were obtained. Of the 399 participants, 4% (n = 16) were vitamin D deficient (25OH-D < 20 ng/mL). There was no association between 25OH-D, serum or CSF VDBP, and HAND stage at baseline or follow-up. Future studies in a population with higher levels of vitamin D deficiency may be warranted. More... »

PAGES

1-5

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s13365-018-00719-6

DOI

http://dx.doi.org/10.1007/s13365-018-00719-6

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1111604717

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30671778


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