Clinical features of fatty liver in nonobese Japanese without regular alcohol intake View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2014-05-22

AUTHORS

Atsushi Hiraoka, Yusuke Imai, Yuki Shinbata, Toshihiko Aibiki, Tomonari Okudaira, Akiko Shiraishi, Haruka Tatsukawa, Tomoe Kawamura, Hiroka Yamago, Hiromasa Nakahara, Nobuaki Azemoto, Tetsuya Tanihira, Hideki Miyata, Tomoyuki Ninomiya, Hisaka Minami, Masashi Hirooka, Masanori Abe, Bunzo Matsuura, Yoichi Hiasa, Kojiro Michitaka

ABSTRACT

AimThe clinical features of fatty liver (FL) detected by ultrasonography (US) in nonobese and diabetes mellitus type 2 are not yet understood, and metabolic syndrome (MetS) has become an important health issue throughout the world. We investigated the clinical features of fatty liver (FL) in nonobese patients.MethodsFrom 2008 to 2010, 2192 Japanese patients underwent a medical checkup at our hospital. Obesity was defined as a body mass index (BMI) ≥25 kg/m2, while normal waist circumference (WC) was defined as <85 cm in males and <90 cm in females. FL was determined in 958 after excluding subjects who regularly drank alcohol (≥20 g/day), who were obese, or had an abnormal WC. We evaluated the clinical backgrounds [biological and lipid examination results, fasting blood sugar, hemoglobin A1c, insulin, HOMA-R, blood pressure (BP), BMI, and medical interviews].ResultsBP, triglyceride, and HOMA-R levels were significantly elevated in nonobese with normal WC with FL (males: 122/78 vs. 120/76 mmHg, 161.5 vs. 105.5 mg/dl, 1.9 vs. 1.3, respectively; females: 120/73 vs. 116/71 mmHg, 115.2 vs. 82.0 mg/dl, 1.7 vs. 1.3, respectively). Both males and females with FL had a past history of increased body weight over 10 kg after reaching the age of 20 years as compared to those without FL (P < 0.01 and P = 0.04, respectively).ConclusionNonobese subjects with normal WC and FL had significantly higher BP, triglyceride, and HOMA-R levels than nonobese subjects with normal WC without FL. Lifestyle instruction should be given to such individuals to prevent insulin resistance and progression to MetS. More... »

PAGES

60-65

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s13340-014-0175-x

DOI

http://dx.doi.org/10.1007/s13340-014-0175-x

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1033793793


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Gastroenterology Center, Ehime Prefectural Central Hospital, Kasuga-Cho 83, 790-0024, Matsuyama, Ehime, Japan", 
          "id": "http://www.grid.ac/institutes/grid.414413.7", 
          "name": [
            "Gastroenterology Center, Ehime Prefectural Central Hospital, Kasuga-Cho 83, 790-0024, Matsuyama, Ehime, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hiraoka", 
        "givenName": "Atsushi", 
        "id": "sg:person.0610141163.37", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0610141163.37"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Gastroenterology Center, Ehime Prefectural Central Hospital, Kasuga-Cho 83, 790-0024, Matsuyama, Ehime, Japan", 
          "id": "http://www.grid.ac/institutes/grid.414413.7", 
          "name": [
            "Gastroenterology Center, Ehime Prefectural Central Hospital, Kasuga-Cho 83, 790-0024, Matsuyama, Ehime, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Imai", 
        "givenName": "Yusuke", 
        "id": "sg:person.0706406515.30", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0706406515.30"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Laboratory, Ehime Prefectural Central Hospital, Matsuyama, Ehime, Japan", 
          "id": "http://www.grid.ac/institutes/grid.414413.7", 
          "name": [
            "Laboratory, Ehime Prefectural Central Hospital, Matsuyama, Ehime, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Shinbata", 
        "givenName": "Yuki", 
        "id": "sg:person.01336527077.13", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01336527077.13"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Gastroenterology Center, Ehime Prefectural Central Hospital, Kasuga-Cho 83, 790-0024, Matsuyama, Ehime, Japan", 
          "id": "http://www.grid.ac/institutes/grid.414413.7", 
          "name": [
            "Gastroenterology Center, Ehime Prefectural Central Hospital, Kasuga-Cho 83, 790-0024, Matsuyama, Ehime, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Aibiki", 
        "givenName": "Toshihiko", 
        "id": "sg:person.014130564371.08", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014130564371.08"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Gastroenterology Center, Ehime Prefectural Central Hospital, Kasuga-Cho 83, 790-0024, Matsuyama, Ehime, Japan", 
          "id": "http://www.grid.ac/institutes/grid.414413.7", 
          "name": [
            "Gastroenterology Center, Ehime Prefectural Central Hospital, Kasuga-Cho 83, 790-0024, Matsuyama, Ehime, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Okudaira", 
        "givenName": "Tomonari", 
        "id": "sg:person.0701622464.95", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0701622464.95"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Gastroenterology Center, Ehime Prefectural Central Hospital, Kasuga-Cho 83, 790-0024, Matsuyama, Ehime, Japan", 
          "id": "http://www.grid.ac/institutes/grid.414413.7", 
          "name": [
            "Gastroenterology Center, Ehime Prefectural Central Hospital, Kasuga-Cho 83, 790-0024, Matsuyama, Ehime, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Shiraishi", 
        "givenName": "Akiko", 
        "id": "sg:person.012234566131.90", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012234566131.90"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Gastroenterology Center, Ehime Prefectural Central Hospital, Kasuga-Cho 83, 790-0024, Matsuyama, Ehime, Japan", 
          "id": "http://www.grid.ac/institutes/grid.414413.7", 
          "name": [
            "Gastroenterology Center, Ehime Prefectural Central Hospital, Kasuga-Cho 83, 790-0024, Matsuyama, Ehime, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tatsukawa", 
        "givenName": "Haruka", 
        "id": "sg:person.01022635115.78", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01022635115.78"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Gastroenterology Center, Ehime Prefectural Central Hospital, Kasuga-Cho 83, 790-0024, Matsuyama, Ehime, Japan", 
          "id": "http://www.grid.ac/institutes/grid.414413.7", 
          "name": [
            "Gastroenterology Center, Ehime Prefectural Central Hospital, Kasuga-Cho 83, 790-0024, Matsuyama, Ehime, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kawamura", 
        "givenName": "Tomoe", 
        "id": "sg:person.01357113364.92", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01357113364.92"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Gastroenterology Center, Ehime Prefectural Central Hospital, Kasuga-Cho 83, 790-0024, Matsuyama, Ehime, Japan", 
          "id": "http://www.grid.ac/institutes/grid.414413.7", 
          "name": [
            "Gastroenterology Center, Ehime Prefectural Central Hospital, Kasuga-Cho 83, 790-0024, Matsuyama, Ehime, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Yamago", 
        "givenName": "Hiroka", 
        "id": "sg:person.015144667263.02", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015144667263.02"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Gastroenterology Center, Ehime Prefectural Central Hospital, Kasuga-Cho 83, 790-0024, Matsuyama, Ehime, Japan", 
          "id": "http://www.grid.ac/institutes/grid.414413.7", 
          "name": [
            "Gastroenterology Center, Ehime Prefectural Central Hospital, Kasuga-Cho 83, 790-0024, Matsuyama, Ehime, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nakahara", 
        "givenName": "Hiromasa", 
        "id": "sg:person.01163136750.50", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01163136750.50"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Gastroenterology Center, Ehime Prefectural Central Hospital, Kasuga-Cho 83, 790-0024, Matsuyama, Ehime, Japan", 
          "id": "http://www.grid.ac/institutes/grid.414413.7", 
          "name": [
            "Gastroenterology Center, Ehime Prefectural Central Hospital, Kasuga-Cho 83, 790-0024, Matsuyama, Ehime, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Azemoto", 
        "givenName": "Nobuaki", 
        "id": "sg:person.01346462503.70", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01346462503.70"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Gastroenterology Center, Ehime Prefectural Central Hospital, Kasuga-Cho 83, 790-0024, Matsuyama, Ehime, Japan", 
          "id": "http://www.grid.ac/institutes/grid.414413.7", 
          "name": [
            "Gastroenterology Center, Ehime Prefectural Central Hospital, Kasuga-Cho 83, 790-0024, Matsuyama, Ehime, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tanihira", 
        "givenName": "Tetsuya", 
        "id": "sg:person.01076115445.53", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01076115445.53"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Gastroenterology Center, Ehime Prefectural Central Hospital, Kasuga-Cho 83, 790-0024, Matsuyama, Ehime, Japan", 
          "id": "http://www.grid.ac/institutes/grid.414413.7", 
          "name": [
            "Gastroenterology Center, Ehime Prefectural Central Hospital, Kasuga-Cho 83, 790-0024, Matsuyama, Ehime, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Miyata", 
        "givenName": "Hideki", 
        "id": "sg:person.01043767743.49", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01043767743.49"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Gastroenterology Center, Ehime Prefectural Central Hospital, Kasuga-Cho 83, 790-0024, Matsuyama, Ehime, Japan", 
          "id": "http://www.grid.ac/institutes/grid.414413.7", 
          "name": [
            "Gastroenterology Center, Ehime Prefectural Central Hospital, Kasuga-Cho 83, 790-0024, Matsuyama, Ehime, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ninomiya", 
        "givenName": "Tomoyuki", 
        "id": "sg:person.01351513052.88", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01351513052.88"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon, Ehime, Japan", 
          "id": "http://www.grid.ac/institutes/grid.255464.4", 
          "name": [
            "Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon, Ehime, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Minami", 
        "givenName": "Hisaka", 
        "id": "sg:person.0705503166.09", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0705503166.09"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon, Ehime, Japan", 
          "id": "http://www.grid.ac/institutes/grid.255464.4", 
          "name": [
            "Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon, Ehime, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hirooka", 
        "givenName": "Masashi", 
        "id": "sg:person.01264716052.47", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01264716052.47"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon, Ehime, Japan", 
          "id": "http://www.grid.ac/institutes/grid.255464.4", 
          "name": [
            "Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon, Ehime, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Abe", 
        "givenName": "Masanori", 
        "id": "sg:person.014763264214.31", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014763264214.31"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon, Ehime, Japan", 
          "id": "http://www.grid.ac/institutes/grid.255464.4", 
          "name": [
            "Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon, Ehime, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Matsuura", 
        "givenName": "Bunzo", 
        "id": "sg:person.0607425152.67", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0607425152.67"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon, Ehime, Japan", 
          "id": "http://www.grid.ac/institutes/grid.255464.4", 
          "name": [
            "Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon, Ehime, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hiasa", 
        "givenName": "Yoichi", 
        "id": "sg:person.01333031252.69", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01333031252.69"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Gastroenterology Center, Ehime Prefectural Central Hospital, Kasuga-Cho 83, 790-0024, Matsuyama, Ehime, Japan", 
          "id": "http://www.grid.ac/institutes/grid.414413.7", 
          "name": [
            "Gastroenterology Center, Ehime Prefectural Central Hospital, Kasuga-Cho 83, 790-0024, Matsuyama, Ehime, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Michitaka", 
        "givenName": "Kojiro", 
        "id": "sg:person.0655540352.56", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0655540352.56"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/s00535-012-0650-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020350237", 
          "https://doi.org/10.1007/s00535-012-0650-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nm0404-325", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035980634", 
          "https://doi.org/10.1038/nm0404-325"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00535-003-1178-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005542799", 
          "https://doi.org/10.1007/s00535-003-1178-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ajg.2011.400", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044576260", 
          "https://doi.org/10.1038/ajg.2011.400"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/scientificamerican0907-72", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001943188", 
          "https://doi.org/10.1038/scientificamerican0907-72"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00535-012-0534-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025763877", 
          "https://doi.org/10.1007/s00535-012-0534-y"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ajg.2012.314", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049334643", 
          "https://doi.org/10.1038/ajg.2012.314"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2014-05-22", 
    "datePublishedReg": "2014-05-22", 
    "description": "AimThe clinical features of fatty liver (FL) detected by ultrasonography (US) in nonobese and diabetes mellitus type 2 are not yet understood, and metabolic syndrome (MetS) has become an important health issue throughout the world. We investigated the clinical features of fatty liver (FL) in nonobese patients.MethodsFrom 2008 to 2010, 2192 Japanese patients underwent a medical checkup at our hospital. Obesity was defined as a body mass index (BMI) \u226525\u00a0kg/m2, while normal waist circumference (WC) was defined as <85\u00a0cm in males and <90\u00a0cm in females. FL was determined in 958 after excluding subjects who regularly drank alcohol (\u226520\u00a0g/day), who were obese, or had an abnormal WC. We evaluated the clinical backgrounds [biological and lipid examination results, fasting blood sugar, hemoglobin A1c, insulin, HOMA-R, blood pressure (BP), BMI, and medical interviews].ResultsBP, triglyceride, and HOMA-R levels were significantly elevated in nonobese with normal WC with FL (males: 122/78 vs. 120/76\u00a0mmHg, 161.5 vs. 105.5\u00a0mg/dl, 1.9 vs. 1.3, respectively; females: 120/73 vs. 116/71\u00a0mmHg, 115.2 vs. 82.0\u00a0mg/dl, 1.7 vs. 1.3, respectively). Both males and females with FL had a past history of increased body weight over 10\u00a0kg after reaching the age of 20\u00a0years as compared to those without FL (P\u00a0<\u00a00.01 and P\u00a0=\u00a00.04, respectively).ConclusionNonobese subjects with normal WC and FL had significantly higher BP, triglyceride, and HOMA-R levels than nonobese subjects with normal WC without FL. Lifestyle instruction should be given to such individuals to prevent insulin resistance and progression to MetS.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/s13340-014-0175-x", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1044715", 
        "issn": [
          "2190-1678", 
          "2190-1686"
        ], 
        "name": "Diabetology International", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "6"
      }
    ], 
    "keywords": [
      "normal waist circumference", 
      "HOMA-R levels", 
      "waist circumference", 
      "fatty liver", 
      "body mass index", 
      "clinical features", 
      "abnormal waist circumference", 
      "mellitus type 2", 
      "regular alcohol intake", 
      "important health issue", 
      "MethodsFrom 2008", 
      "nonobese patients", 
      "metabolic syndrome", 
      "mass index", 
      "high BP", 
      "nonobese subjects", 
      "alcohol intake", 
      "insulin resistance", 
      "medical checkup", 
      "Japanese patients", 
      "clinical background", 
      "body weight", 
      "lifestyle instructions", 
      "type 2", 
      "health issues", 
      "past history", 
      "liver", 
      "nonobese", 
      "patients", 
      "ultrasonography", 
      "triglycerides", 
      "such individuals", 
      "subjects", 
      "males", 
      "females", 
      "MetS.", 
      "obesity", 
      "checkup", 
      "syndrome", 
      "hospital", 
      "intake", 
      "progression", 
      "circumference", 
      "age", 
      "levels", 
      "years", 
      "individuals", 
      "index", 
      "history", 
      "weight", 
      "features", 
      "background", 
      "alcohol", 
      "m2", 
      "resistance", 
      "Japanese", 
      "BP", 
      "instruction", 
      "issues", 
      "world"
    ], 
    "name": "Clinical features of fatty liver in nonobese Japanese without regular alcohol intake", 
    "pagination": "60-65", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1033793793"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s13340-014-0175-x"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s13340-014-0175-x", 
      "https://app.dimensions.ai/details/publication/pub.1033793793"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-12-01T06:31", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20221201/entities/gbq_results/article/article_618.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/s13340-014-0175-x"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s13340-014-0175-x'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s13340-014-0175-x'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s13340-014-0175-x'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s13340-014-0175-x'


 

This table displays all metadata directly associated to this object as RDF triples.

283 TRIPLES      21 PREDICATES      91 URIs      76 LITERALS      6 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s13340-014-0175-x schema:about anzsrc-for:11
2 anzsrc-for:1103
3 schema:author Na93befd2124b4b8fbaa37dc653268922
4 schema:citation sg:pub.10.1007/s00535-003-1178-8
5 sg:pub.10.1007/s00535-012-0534-y
6 sg:pub.10.1007/s00535-012-0650-8
7 sg:pub.10.1038/ajg.2011.400
8 sg:pub.10.1038/ajg.2012.314
9 sg:pub.10.1038/nm0404-325
10 sg:pub.10.1038/scientificamerican0907-72
11 schema:datePublished 2014-05-22
12 schema:datePublishedReg 2014-05-22
13 schema:description AimThe clinical features of fatty liver (FL) detected by ultrasonography (US) in nonobese and diabetes mellitus type 2 are not yet understood, and metabolic syndrome (MetS) has become an important health issue throughout the world. We investigated the clinical features of fatty liver (FL) in nonobese patients.MethodsFrom 2008 to 2010, 2192 Japanese patients underwent a medical checkup at our hospital. Obesity was defined as a body mass index (BMI) ≥25 kg/m2, while normal waist circumference (WC) was defined as <85 cm in males and <90 cm in females. FL was determined in 958 after excluding subjects who regularly drank alcohol (≥20 g/day), who were obese, or had an abnormal WC. We evaluated the clinical backgrounds [biological and lipid examination results, fasting blood sugar, hemoglobin A1c, insulin, HOMA-R, blood pressure (BP), BMI, and medical interviews].ResultsBP, triglyceride, and HOMA-R levels were significantly elevated in nonobese with normal WC with FL (males: 122/78 vs. 120/76 mmHg, 161.5 vs. 105.5 mg/dl, 1.9 vs. 1.3, respectively; females: 120/73 vs. 116/71 mmHg, 115.2 vs. 82.0 mg/dl, 1.7 vs. 1.3, respectively). Both males and females with FL had a past history of increased body weight over 10 kg after reaching the age of 20 years as compared to those without FL (P < 0.01 and P = 0.04, respectively).ConclusionNonobese subjects with normal WC and FL had significantly higher BP, triglyceride, and HOMA-R levels than nonobese subjects with normal WC without FL. Lifestyle instruction should be given to such individuals to prevent insulin resistance and progression to MetS.
14 schema:genre article
15 schema:isAccessibleForFree false
16 schema:isPartOf N17d7cdf92ffe49ae973fcfa2ddc9184d
17 N8a9b22556bde4bfcbc1070f7a32d6816
18 sg:journal.1044715
19 schema:keywords BP
20 HOMA-R levels
21 Japanese
22 Japanese patients
23 MetS.
24 MethodsFrom 2008
25 abnormal waist circumference
26 age
27 alcohol
28 alcohol intake
29 background
30 body mass index
31 body weight
32 checkup
33 circumference
34 clinical background
35 clinical features
36 fatty liver
37 features
38 females
39 health issues
40 high BP
41 history
42 hospital
43 important health issue
44 index
45 individuals
46 instruction
47 insulin resistance
48 intake
49 issues
50 levels
51 lifestyle instructions
52 liver
53 m2
54 males
55 mass index
56 medical checkup
57 mellitus type 2
58 metabolic syndrome
59 nonobese
60 nonobese patients
61 nonobese subjects
62 normal waist circumference
63 obesity
64 past history
65 patients
66 progression
67 regular alcohol intake
68 resistance
69 subjects
70 such individuals
71 syndrome
72 triglycerides
73 type 2
74 ultrasonography
75 waist circumference
76 weight
77 world
78 years
79 schema:name Clinical features of fatty liver in nonobese Japanese without regular alcohol intake
80 schema:pagination 60-65
81 schema:productId N27972aec4c004e43a3a7f269fc64d652
82 Nd0447d86f8f54e61a78607ca29f061d9
83 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033793793
84 https://doi.org/10.1007/s13340-014-0175-x
85 schema:sdDatePublished 2022-12-01T06:31
86 schema:sdLicense https://scigraph.springernature.com/explorer/license/
87 schema:sdPublisher Ne6946e7b31cf4500ba500363fa64142b
88 schema:url https://doi.org/10.1007/s13340-014-0175-x
89 sgo:license sg:explorer/license/
90 sgo:sdDataset articles
91 rdf:type schema:ScholarlyArticle
92 N112c2f8e8e2748e4b6f26261a8299a7d rdf:first sg:person.01043767743.49
93 rdf:rest Ncbabd963eb64465b889fe3b40c0ab898
94 N118c6ab8f73b4aef911b3f32fa4530ed rdf:first sg:person.01336527077.13
95 rdf:rest Nb901cb0f3bb64e0e860362c6c4225471
96 N17d7cdf92ffe49ae973fcfa2ddc9184d schema:volumeNumber 6
97 rdf:type schema:PublicationVolume
98 N27972aec4c004e43a3a7f269fc64d652 schema:name doi
99 schema:value 10.1007/s13340-014-0175-x
100 rdf:type schema:PropertyValue
101 N36c37360f3db4179975e90463ef92b99 rdf:first sg:person.0705503166.09
102 rdf:rest Nee15627298634d49960d5cb3d2168b90
103 N53a7f3e062934bcba222c7bc8dba575a rdf:first sg:person.014763264214.31
104 rdf:rest N7070d80e93f946c48f12b8233bc767fc
105 N60c39ff82ca64989800c281eb8c456af rdf:first sg:person.01346462503.70
106 rdf:rest Nadcab776b64d4165a9027ba534e62994
107 N67749b2bc73245669ab25f12153a5af2 rdf:first sg:person.0706406515.30
108 rdf:rest N118c6ab8f73b4aef911b3f32fa4530ed
109 N7070d80e93f946c48f12b8233bc767fc rdf:first sg:person.0607425152.67
110 rdf:rest Na46c0ec435964c20a29fd37642da9aa1
111 N8a9b22556bde4bfcbc1070f7a32d6816 schema:issueNumber 1
112 rdf:type schema:PublicationIssue
113 N8c548fc9dccd48d982bf62e7685d9f97 rdf:first sg:person.015144667263.02
114 rdf:rest Nd838c562b2a342fdbcfba3b8a24bd759
115 N9cc576ec3b3d4b59b91521d9f841273a rdf:first sg:person.01357113364.92
116 rdf:rest N8c548fc9dccd48d982bf62e7685d9f97
117 Na46c0ec435964c20a29fd37642da9aa1 rdf:first sg:person.01333031252.69
118 rdf:rest Nd108fd3b865643baa4d555c94562bf6c
119 Na93befd2124b4b8fbaa37dc653268922 rdf:first sg:person.0610141163.37
120 rdf:rest N67749b2bc73245669ab25f12153a5af2
121 Nadcab776b64d4165a9027ba534e62994 rdf:first sg:person.01076115445.53
122 rdf:rest N112c2f8e8e2748e4b6f26261a8299a7d
123 Nb0706f30fa4d43f09061f395d14cbc0a rdf:first sg:person.0701622464.95
124 rdf:rest Nd5703bca3cd846fa84b15e611863c4a5
125 Nb901cb0f3bb64e0e860362c6c4225471 rdf:first sg:person.014130564371.08
126 rdf:rest Nb0706f30fa4d43f09061f395d14cbc0a
127 Ncbabd963eb64465b889fe3b40c0ab898 rdf:first sg:person.01351513052.88
128 rdf:rest N36c37360f3db4179975e90463ef92b99
129 Nd0447d86f8f54e61a78607ca29f061d9 schema:name dimensions_id
130 schema:value pub.1033793793
131 rdf:type schema:PropertyValue
132 Nd108fd3b865643baa4d555c94562bf6c rdf:first sg:person.0655540352.56
133 rdf:rest rdf:nil
134 Nd5703bca3cd846fa84b15e611863c4a5 rdf:first sg:person.012234566131.90
135 rdf:rest Nd9e27434ab1847869bb8f3a9df3268ba
136 Nd838c562b2a342fdbcfba3b8a24bd759 rdf:first sg:person.01163136750.50
137 rdf:rest N60c39ff82ca64989800c281eb8c456af
138 Nd9e27434ab1847869bb8f3a9df3268ba rdf:first sg:person.01022635115.78
139 rdf:rest N9cc576ec3b3d4b59b91521d9f841273a
140 Ne6946e7b31cf4500ba500363fa64142b schema:name Springer Nature - SN SciGraph project
141 rdf:type schema:Organization
142 Nee15627298634d49960d5cb3d2168b90 rdf:first sg:person.01264716052.47
143 rdf:rest N53a7f3e062934bcba222c7bc8dba575a
144 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
145 schema:name Medical and Health Sciences
146 rdf:type schema:DefinedTerm
147 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
148 schema:name Clinical Sciences
149 rdf:type schema:DefinedTerm
150 sg:journal.1044715 schema:issn 2190-1678
151 2190-1686
152 schema:name Diabetology International
153 schema:publisher Springer Nature
154 rdf:type schema:Periodical
155 sg:person.01022635115.78 schema:affiliation grid-institutes:grid.414413.7
156 schema:familyName Tatsukawa
157 schema:givenName Haruka
158 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01022635115.78
159 rdf:type schema:Person
160 sg:person.01043767743.49 schema:affiliation grid-institutes:grid.414413.7
161 schema:familyName Miyata
162 schema:givenName Hideki
163 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01043767743.49
164 rdf:type schema:Person
165 sg:person.01076115445.53 schema:affiliation grid-institutes:grid.414413.7
166 schema:familyName Tanihira
167 schema:givenName Tetsuya
168 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01076115445.53
169 rdf:type schema:Person
170 sg:person.01163136750.50 schema:affiliation grid-institutes:grid.414413.7
171 schema:familyName Nakahara
172 schema:givenName Hiromasa
173 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01163136750.50
174 rdf:type schema:Person
175 sg:person.012234566131.90 schema:affiliation grid-institutes:grid.414413.7
176 schema:familyName Shiraishi
177 schema:givenName Akiko
178 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012234566131.90
179 rdf:type schema:Person
180 sg:person.01264716052.47 schema:affiliation grid-institutes:grid.255464.4
181 schema:familyName Hirooka
182 schema:givenName Masashi
183 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01264716052.47
184 rdf:type schema:Person
185 sg:person.01333031252.69 schema:affiliation grid-institutes:grid.255464.4
186 schema:familyName Hiasa
187 schema:givenName Yoichi
188 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01333031252.69
189 rdf:type schema:Person
190 sg:person.01336527077.13 schema:affiliation grid-institutes:grid.414413.7
191 schema:familyName Shinbata
192 schema:givenName Yuki
193 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01336527077.13
194 rdf:type schema:Person
195 sg:person.01346462503.70 schema:affiliation grid-institutes:grid.414413.7
196 schema:familyName Azemoto
197 schema:givenName Nobuaki
198 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01346462503.70
199 rdf:type schema:Person
200 sg:person.01351513052.88 schema:affiliation grid-institutes:grid.414413.7
201 schema:familyName Ninomiya
202 schema:givenName Tomoyuki
203 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01351513052.88
204 rdf:type schema:Person
205 sg:person.01357113364.92 schema:affiliation grid-institutes:grid.414413.7
206 schema:familyName Kawamura
207 schema:givenName Tomoe
208 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01357113364.92
209 rdf:type schema:Person
210 sg:person.014130564371.08 schema:affiliation grid-institutes:grid.414413.7
211 schema:familyName Aibiki
212 schema:givenName Toshihiko
213 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014130564371.08
214 rdf:type schema:Person
215 sg:person.014763264214.31 schema:affiliation grid-institutes:grid.255464.4
216 schema:familyName Abe
217 schema:givenName Masanori
218 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014763264214.31
219 rdf:type schema:Person
220 sg:person.015144667263.02 schema:affiliation grid-institutes:grid.414413.7
221 schema:familyName Yamago
222 schema:givenName Hiroka
223 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015144667263.02
224 rdf:type schema:Person
225 sg:person.0607425152.67 schema:affiliation grid-institutes:grid.255464.4
226 schema:familyName Matsuura
227 schema:givenName Bunzo
228 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0607425152.67
229 rdf:type schema:Person
230 sg:person.0610141163.37 schema:affiliation grid-institutes:grid.414413.7
231 schema:familyName Hiraoka
232 schema:givenName Atsushi
233 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0610141163.37
234 rdf:type schema:Person
235 sg:person.0655540352.56 schema:affiliation grid-institutes:grid.414413.7
236 schema:familyName Michitaka
237 schema:givenName Kojiro
238 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0655540352.56
239 rdf:type schema:Person
240 sg:person.0701622464.95 schema:affiliation grid-institutes:grid.414413.7
241 schema:familyName Okudaira
242 schema:givenName Tomonari
243 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0701622464.95
244 rdf:type schema:Person
245 sg:person.0705503166.09 schema:affiliation grid-institutes:grid.255464.4
246 schema:familyName Minami
247 schema:givenName Hisaka
248 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0705503166.09
249 rdf:type schema:Person
250 sg:person.0706406515.30 schema:affiliation grid-institutes:grid.414413.7
251 schema:familyName Imai
252 schema:givenName Yusuke
253 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0706406515.30
254 rdf:type schema:Person
255 sg:pub.10.1007/s00535-003-1178-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005542799
256 https://doi.org/10.1007/s00535-003-1178-8
257 rdf:type schema:CreativeWork
258 sg:pub.10.1007/s00535-012-0534-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1025763877
259 https://doi.org/10.1007/s00535-012-0534-y
260 rdf:type schema:CreativeWork
261 sg:pub.10.1007/s00535-012-0650-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020350237
262 https://doi.org/10.1007/s00535-012-0650-8
263 rdf:type schema:CreativeWork
264 sg:pub.10.1038/ajg.2011.400 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044576260
265 https://doi.org/10.1038/ajg.2011.400
266 rdf:type schema:CreativeWork
267 sg:pub.10.1038/ajg.2012.314 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049334643
268 https://doi.org/10.1038/ajg.2012.314
269 rdf:type schema:CreativeWork
270 sg:pub.10.1038/nm0404-325 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035980634
271 https://doi.org/10.1038/nm0404-325
272 rdf:type schema:CreativeWork
273 sg:pub.10.1038/scientificamerican0907-72 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001943188
274 https://doi.org/10.1038/scientificamerican0907-72
275 rdf:type schema:CreativeWork
276 grid-institutes:grid.255464.4 schema:alternateName Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon, Ehime, Japan
277 schema:name Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon, Ehime, Japan
278 rdf:type schema:Organization
279 grid-institutes:grid.414413.7 schema:alternateName Gastroenterology Center, Ehime Prefectural Central Hospital, Kasuga-Cho 83, 790-0024, Matsuyama, Ehime, Japan
280 Laboratory, Ehime Prefectural Central Hospital, Matsuyama, Ehime, Japan
281 schema:name Gastroenterology Center, Ehime Prefectural Central Hospital, Kasuga-Cho 83, 790-0024, Matsuyama, Ehime, Japan
282 Laboratory, Ehime Prefectural Central Hospital, Matsuyama, Ehime, Japan
283 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...