The ALPPS procedure: hepatocellular carcinoma as a main indication. An Italian single-center experience View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-03

AUTHORS

Giovanni Vennarecci, Daniele Ferraro, Antonella Tudisco, Giovanni Battista Levi Sandri, Nicola Guglielmo, Giammauro Berardi, Isabella Sperduti, Giuseppe Maria Ettorre

ABSTRACT

The ALPPS is a technique that allows achieving hepatic resection by a rapid future liver remnant hypertrophy. The aim of this study was to report the experience of an Italian center with ALPPS in patients with liver tumors. A retrospective analysis of patients undergoing ALPPS between 2012 and 2017 was performed. Patients' characteristics and disease presentation, increase in future liver remnant (FLR) as well as intraoperative and postoperative short- and long-term outcomes were evaluated. A total of 24 patients underwent the ALPPS procedure: 17 procedures for hepatocarcinoma (HCC), 5 for colorectal liver metastases (CRLM), 1 for cholangiocarcinoma (CC) and 1 for Merkel Cell Carcinoma liver metastasis (MCCLM). Macrovascular invasion (MVI) was recorded in 10 (41.6%) patients: 8 (33.3%) patients with HCC had invasion of portal vein (5), middle hepatic vein (2) and inferior vena cava (1). One patient with CRLM had involvement of middle hepatic vein and one patient with CC had involvement of right portal vein and middle hepatic vein. A p-ALPPS in 14 cases (58.3%), 10 t-ALPPS (41.6%) and hanging maneuver in 19 patients (80%) were performed. Median postoperative stay was 26 days (range 16-68 days). 90-day mortality was 8.3% (two patients, one with CC and one with HCC), 90-day mortality for HCC was 5.8%. After stage 1, we counted 15 complications all of grade I; after stage 2 the number of complications was increased to 37:33 were of grade I and 4 were of grade IV. R0 resection was achieved in all patients with 100% oncology feasibility. After a median follow-up of 10 months (range 2-54), disease recurrence has been recorded in 6 patients with HCC and in 2 with CRLM. Eleven patients died, nine affected by HCC, one by CRLM, and one by CC. 2-years OS and disease-free survival (DFS) for the entire group were 47.3% and 47.5%, respectively. Concerning patients operated on for HCC, the 2-years OS and DFS were 38.5% and 60%, respectively. The ALPPS procedure is an interesting approach for large primary or secondary liver tumor with small FLR above all for large HCC associated with MVI, with acceptable OS and DFS. More... »

PAGES

1-9

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s13304-018-0596-3

DOI

http://dx.doi.org/10.1007/s13304-018-0596-3

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1107221074

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30255436


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Ospedale San Camillo", 
          "id": "https://www.grid.ac/institutes/grid.416308.8", 
          "name": [
            "Division of General Surgery and Liver Transplantation, S. Camillo Hospital, Circ.ne Gianicolense 87, 00151, Rome, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Vennarecci", 
        "givenName": "Giovanni", 
        "id": "sg:person.0611306744.39", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0611306744.39"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Ospedale San Camillo", 
          "id": "https://www.grid.ac/institutes/grid.416308.8", 
          "name": [
            "Division of General Surgery and Liver Transplantation, S. Camillo Hospital, Circ.ne Gianicolense 87, 00151, Rome, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ferraro", 
        "givenName": "Daniele", 
        "id": "sg:person.012066426321.71", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012066426321.71"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Ospedale San Camillo", 
          "id": "https://www.grid.ac/institutes/grid.416308.8", 
          "name": [
            "Division of General Surgery and Liver Transplantation, S. Camillo Hospital, Circ.ne Gianicolense 87, 00151, Rome, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tudisco", 
        "givenName": "Antonella", 
        "id": "sg:person.01042474563.38", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01042474563.38"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Ospedale San Camillo", 
          "id": "https://www.grid.ac/institutes/grid.416308.8", 
          "name": [
            "Division of General Surgery and Liver Transplantation, S. Camillo Hospital, Circ.ne Gianicolense 87, 00151, Rome, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Levi Sandri", 
        "givenName": "Giovanni Battista", 
        "id": "sg:person.012321242741.24", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012321242741.24"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Ospedale San Camillo", 
          "id": "https://www.grid.ac/institutes/grid.416308.8", 
          "name": [
            "Division of General Surgery and Liver Transplantation, S. Camillo Hospital, Circ.ne Gianicolense 87, 00151, Rome, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Guglielmo", 
        "givenName": "Nicola", 
        "id": "sg:person.01343325771.54", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01343325771.54"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Ospedale San Camillo", 
          "id": "https://www.grid.ac/institutes/grid.416308.8", 
          "name": [
            "Division of General Surgery and Liver Transplantation, S. Camillo Hospital, Circ.ne Gianicolense 87, 00151, Rome, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Berardi", 
        "givenName": "Giammauro", 
        "id": "sg:person.0747272364.59", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0747272364.59"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Istituti Fisioterapici Ospitalieri", 
          "id": "https://www.grid.ac/institutes/grid.417520.5", 
          "name": [
            "Biostatistical Unit, Regina Elena National Cancer Institute, Rome, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sperduti", 
        "givenName": "Isabella", 
        "id": "sg:person.01323700675.54", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01323700675.54"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Ospedale San Camillo", 
          "id": "https://www.grid.ac/institutes/grid.416308.8", 
          "name": [
            "Division of General Surgery and Liver Transplantation, S. Camillo Hospital, Circ.ne Gianicolense 87, 00151, Rome, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ettorre", 
        "givenName": "Giuseppe Maria", 
        "id": "sg:person.01153514070.86", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01153514070.86"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1097/sla.0000000000001087", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003288281"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sla.0000000000001087", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003288281"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1245/s10434-015-5007-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004467227", 
          "https://doi.org/10.1245/s10434-015-5007-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jhep.2016.05.044", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004650844"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jhep.2016.05.044", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004650844"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s13304-016-0401-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008564505", 
          "https://doi.org/10.1007/s13304-016-0401-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s13304-016-0401-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008564505", 
          "https://doi.org/10.1007/s13304-016-0401-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.sla.0000048447.16651.7b", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008677963"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.sla.0000048447.16651.7b", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008677963"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/hpb.12386", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013526410"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11605-012-2029-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014548529", 
          "https://doi.org/10.1007/s11605-012-2029-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.hpb.2016.02.003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017676777"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ejso.2015.01.004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019154592"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ijsu.2016.04.031", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021573241"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sla.0b013e31824856f5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022177341"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sla.0b013e31824856f5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022177341"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ijsu.2014.11.054", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023197526"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11605-012-2092-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029542393", 
          "https://doi.org/10.1007/s11605-012-2092-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sla.0000000000001272", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029654558"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sla.0000000000001272", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029654558"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.amjsurg.2008.04.022", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030780261"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00268-013-2401-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035433988", 
          "https://doi.org/10.1007/s00268-013-2401-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1499-3872(15)60414-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036631073"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ijscr.2016.07.039", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039641432"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/bjs.6756", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043375162"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00268-013-2296-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046045667", 
          "https://doi.org/10.1007/s00268-013-2296-y"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00268-014-2513-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046702298", 
          "https://doi.org/10.1007/s00268-014-2513-3"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jamcollsurg.2013.03.004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046823217"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sla.0000000000001007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047210883"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sla.0000000000001007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047210883"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sla.0b013e31815f6e5b", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048452135"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sla.0b013e31815f6e5b", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048452135"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1245/s10434-014-4213-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049561328", 
          "https://doi.org/10.1245/s10434-014-4213-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1245/s10434-014-4291-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049874261", 
          "https://doi.org/10.1245/s10434-014-4291-4"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.sla.0000065265.16728.c0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049992611"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.sla.0000065265.16728.c0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049992611"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jhep.2011.12.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051138497"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/hep.29086", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1074239526"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/1553350617697187", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084247553"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/1553350617697187", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084247553"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/liv.13491", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1085994893"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s13304-017-0481-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1091117074", 
          "https://doi.org/10.1007/s13304-017-0481-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s13304-017-0481-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1091117074", 
          "https://doi.org/10.1007/s13304-017-0481-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.18632/oncotarget.21299", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1091987381"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2019-03", 
    "datePublishedReg": "2019-03-01", 
    "description": "The ALPPS is a technique that allows achieving hepatic resection by a rapid future liver remnant hypertrophy. The aim of this study was to report the experience of an Italian center with ALPPS in patients with liver tumors. A retrospective analysis of patients undergoing ALPPS between 2012 and 2017 was performed. Patients' characteristics and disease presentation, increase in future liver remnant (FLR) as well as intraoperative and postoperative short- and long-term outcomes were evaluated. A total of 24 patients underwent the ALPPS procedure: 17 procedures for hepatocarcinoma (HCC), 5 for colorectal liver metastases (CRLM), 1 for cholangiocarcinoma (CC) and 1 for Merkel Cell Carcinoma liver metastasis (MCCLM). Macrovascular invasion (MVI) was recorded in 10 (41.6%) patients: 8 (33.3%) patients with HCC had invasion of portal vein (5), middle hepatic vein (2) and inferior vena cava (1). One patient with CRLM had involvement of middle hepatic vein and one patient with CC had involvement of right portal vein and middle hepatic vein. A p-ALPPS in 14 cases (58.3%), 10 t-ALPPS (41.6%) and hanging maneuver in 19 patients (80%) were performed. Median postoperative stay was 26\u00a0days (range 16-68\u00a0days). 90-day mortality was 8.3% (two patients, one with CC and one with HCC), 90-day mortality for HCC was 5.8%. After stage 1, we counted 15 complications all of grade I; after stage 2 the number of complications was increased to 37:33 were of grade I and 4 were of grade IV. R0 resection was achieved in all patients with 100% oncology feasibility. After a median follow-up of 10\u00a0months (range 2-54), disease recurrence has been recorded in 6 patients with HCC and in 2 with CRLM. Eleven patients died, nine affected by HCC, one by CRLM, and one by CC. 2-years OS and disease-free survival (DFS) for the entire group were 47.3% and 47.5%, respectively. Concerning patients operated on for HCC, the 2-years OS and DFS were 38.5% and 60%, respectively. The ALPPS procedure is an interesting approach for large primary or secondary liver tumor with small FLR above all for large HCC associated with MVI, with acceptable OS and DFS.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s13304-018-0596-3", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1345415", 
        "issn": [
          "2038-131X", 
          "2038-3312"
        ], 
        "name": "Updates in Surgery", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "71"
      }
    ], 
    "name": "The ALPPS procedure: hepatocellular carcinoma as a main indication. An Italian single-center experience", 
    "pagination": "1-9", 
    "productId": [
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s13304-018-0596-3"
        ]
      }, 
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "0c6981506ba34b512d7271d43eb39dbbbb5e7aae94767947bb80b12a234cf8fb"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1107221074"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101539818"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30255436"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s13304-018-0596-3", 
      "https://app.dimensions.ai/details/publication/pub.1107221074"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-15T08:51", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000374_0000000374/records_119732_00000001.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://link.springer.com/10.1007%2Fs13304-018-0596-3"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s13304-018-0596-3'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s13304-018-0596-3'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s13304-018-0596-3'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s13304-018-0596-3'


 

This table displays all metadata directly associated to this object as RDF triples.

230 TRIPLES      21 PREDICATES      62 URIs      21 LITERALS      9 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s13304-018-0596-3 schema:about anzsrc-for:11
2 anzsrc-for:1103
3 schema:author N122ef46eb7834e1fab0bc1a3eced726d
4 schema:citation sg:pub.10.1007/s00268-013-2296-y
5 sg:pub.10.1007/s00268-013-2401-2
6 sg:pub.10.1007/s00268-014-2513-3
7 sg:pub.10.1007/s11605-012-2029-9
8 sg:pub.10.1007/s11605-012-2092-2
9 sg:pub.10.1007/s13304-016-0401-0
10 sg:pub.10.1007/s13304-017-0481-5
11 sg:pub.10.1245/s10434-014-4213-5
12 sg:pub.10.1245/s10434-014-4291-4
13 sg:pub.10.1245/s10434-015-5007-0
14 https://doi.org/10.1002/bjs.6756
15 https://doi.org/10.1002/hep.29086
16 https://doi.org/10.1016/j.amjsurg.2008.04.022
17 https://doi.org/10.1016/j.ejso.2015.01.004
18 https://doi.org/10.1016/j.hpb.2016.02.003
19 https://doi.org/10.1016/j.ijscr.2016.07.039
20 https://doi.org/10.1016/j.ijsu.2014.11.054
21 https://doi.org/10.1016/j.ijsu.2016.04.031
22 https://doi.org/10.1016/j.jamcollsurg.2013.03.004
23 https://doi.org/10.1016/j.jhep.2011.12.001
24 https://doi.org/10.1016/j.jhep.2016.05.044
25 https://doi.org/10.1016/s1499-3872(15)60414-3
26 https://doi.org/10.1097/01.sla.0000048447.16651.7b
27 https://doi.org/10.1097/01.sla.0000065265.16728.c0
28 https://doi.org/10.1097/sla.0000000000001007
29 https://doi.org/10.1097/sla.0000000000001087
30 https://doi.org/10.1097/sla.0000000000001272
31 https://doi.org/10.1097/sla.0b013e31815f6e5b
32 https://doi.org/10.1097/sla.0b013e31824856f5
33 https://doi.org/10.1111/hpb.12386
34 https://doi.org/10.1111/liv.13491
35 https://doi.org/10.1177/1553350617697187
36 https://doi.org/10.18632/oncotarget.21299
37 schema:datePublished 2019-03
38 schema:datePublishedReg 2019-03-01
39 schema:description The ALPPS is a technique that allows achieving hepatic resection by a rapid future liver remnant hypertrophy. The aim of this study was to report the experience of an Italian center with ALPPS in patients with liver tumors. A retrospective analysis of patients undergoing ALPPS between 2012 and 2017 was performed. Patients' characteristics and disease presentation, increase in future liver remnant (FLR) as well as intraoperative and postoperative short- and long-term outcomes were evaluated. A total of 24 patients underwent the ALPPS procedure: 17 procedures for hepatocarcinoma (HCC), 5 for colorectal liver metastases (CRLM), 1 for cholangiocarcinoma (CC) and 1 for Merkel Cell Carcinoma liver metastasis (MCCLM). Macrovascular invasion (MVI) was recorded in 10 (41.6%) patients: 8 (33.3%) patients with HCC had invasion of portal vein (5), middle hepatic vein (2) and inferior vena cava (1). One patient with CRLM had involvement of middle hepatic vein and one patient with CC had involvement of right portal vein and middle hepatic vein. A p-ALPPS in 14 cases (58.3%), 10 t-ALPPS (41.6%) and hanging maneuver in 19 patients (80%) were performed. Median postoperative stay was 26 days (range 16-68 days). 90-day mortality was 8.3% (two patients, one with CC and one with HCC), 90-day mortality for HCC was 5.8%. After stage 1, we counted 15 complications all of grade I; after stage 2 the number of complications was increased to 37:33 were of grade I and 4 were of grade IV. R0 resection was achieved in all patients with 100% oncology feasibility. After a median follow-up of 10 months (range 2-54), disease recurrence has been recorded in 6 patients with HCC and in 2 with CRLM. Eleven patients died, nine affected by HCC, one by CRLM, and one by CC. 2-years OS and disease-free survival (DFS) for the entire group were 47.3% and 47.5%, respectively. Concerning patients operated on for HCC, the 2-years OS and DFS were 38.5% and 60%, respectively. The ALPPS procedure is an interesting approach for large primary or secondary liver tumor with small FLR above all for large HCC associated with MVI, with acceptable OS and DFS.
40 schema:genre research_article
41 schema:inLanguage en
42 schema:isAccessibleForFree false
43 schema:isPartOf N236a647b08e04e74aa37533bda24c26e
44 N52477c6b5d474dbf886dc17408a59c54
45 sg:journal.1345415
46 schema:name The ALPPS procedure: hepatocellular carcinoma as a main indication. An Italian single-center experience
47 schema:pagination 1-9
48 schema:productId N4ea6438477cc4f048e661ea6d74b315c
49 N508b3dfced944c02ab1f698c0567aea9
50 Naccd7e8e61654f2fb93ecc4f99f2a80a
51 Nb54c9e1081bc45878f1d9f6126bc7801
52 Nc549836a00424db6aa9411efb92b2f77
53 schema:sameAs https://app.dimensions.ai/details/publication/pub.1107221074
54 https://doi.org/10.1007/s13304-018-0596-3
55 schema:sdDatePublished 2019-04-15T08:51
56 schema:sdLicense https://scigraph.springernature.com/explorer/license/
57 schema:sdPublisher Nd09c8030ae524a9fb424f003d1c4c1d8
58 schema:url https://link.springer.com/10.1007%2Fs13304-018-0596-3
59 sgo:license sg:explorer/license/
60 sgo:sdDataset articles
61 rdf:type schema:ScholarlyArticle
62 N10fc21ff34d54f9c903a99d6de93bf6f rdf:first sg:person.012066426321.71
63 rdf:rest N4b0744db692b435fada7bd7708771ec1
64 N122ef46eb7834e1fab0bc1a3eced726d rdf:first sg:person.0611306744.39
65 rdf:rest N10fc21ff34d54f9c903a99d6de93bf6f
66 N236a647b08e04e74aa37533bda24c26e schema:volumeNumber 71
67 rdf:type schema:PublicationVolume
68 N24786c7eb7b345fe9b1eb54875d56592 rdf:first sg:person.01153514070.86
69 rdf:rest rdf:nil
70 N4b0744db692b435fada7bd7708771ec1 rdf:first sg:person.01042474563.38
71 rdf:rest N8421c7ee887946e4bd1e9ce1664ab823
72 N4ea6438477cc4f048e661ea6d74b315c schema:name nlm_unique_id
73 schema:value 101539818
74 rdf:type schema:PropertyValue
75 N508b3dfced944c02ab1f698c0567aea9 schema:name pubmed_id
76 schema:value 30255436
77 rdf:type schema:PropertyValue
78 N52477c6b5d474dbf886dc17408a59c54 schema:issueNumber 1
79 rdf:type schema:PublicationIssue
80 N73e5e0dda28a4fd68a8486db2b23a6e0 rdf:first sg:person.0747272364.59
81 rdf:rest N7f3a5803f256422ca2bcf9395fbc0598
82 N7f3a5803f256422ca2bcf9395fbc0598 rdf:first sg:person.01323700675.54
83 rdf:rest N24786c7eb7b345fe9b1eb54875d56592
84 N8421c7ee887946e4bd1e9ce1664ab823 rdf:first sg:person.012321242741.24
85 rdf:rest Nd7c48f34bc834e51a96f94fc25acc288
86 Naccd7e8e61654f2fb93ecc4f99f2a80a schema:name readcube_id
87 schema:value 0c6981506ba34b512d7271d43eb39dbbbb5e7aae94767947bb80b12a234cf8fb
88 rdf:type schema:PropertyValue
89 Nb54c9e1081bc45878f1d9f6126bc7801 schema:name dimensions_id
90 schema:value pub.1107221074
91 rdf:type schema:PropertyValue
92 Nc549836a00424db6aa9411efb92b2f77 schema:name doi
93 schema:value 10.1007/s13304-018-0596-3
94 rdf:type schema:PropertyValue
95 Nd09c8030ae524a9fb424f003d1c4c1d8 schema:name Springer Nature - SN SciGraph project
96 rdf:type schema:Organization
97 Nd7c48f34bc834e51a96f94fc25acc288 rdf:first sg:person.01343325771.54
98 rdf:rest N73e5e0dda28a4fd68a8486db2b23a6e0
99 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
100 schema:name Medical and Health Sciences
101 rdf:type schema:DefinedTerm
102 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
103 schema:name Clinical Sciences
104 rdf:type schema:DefinedTerm
105 sg:journal.1345415 schema:issn 2038-131X
106 2038-3312
107 schema:name Updates in Surgery
108 rdf:type schema:Periodical
109 sg:person.01042474563.38 schema:affiliation https://www.grid.ac/institutes/grid.416308.8
110 schema:familyName Tudisco
111 schema:givenName Antonella
112 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01042474563.38
113 rdf:type schema:Person
114 sg:person.01153514070.86 schema:affiliation https://www.grid.ac/institutes/grid.416308.8
115 schema:familyName Ettorre
116 schema:givenName Giuseppe Maria
117 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01153514070.86
118 rdf:type schema:Person
119 sg:person.012066426321.71 schema:affiliation https://www.grid.ac/institutes/grid.416308.8
120 schema:familyName Ferraro
121 schema:givenName Daniele
122 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012066426321.71
123 rdf:type schema:Person
124 sg:person.012321242741.24 schema:affiliation https://www.grid.ac/institutes/grid.416308.8
125 schema:familyName Levi Sandri
126 schema:givenName Giovanni Battista
127 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012321242741.24
128 rdf:type schema:Person
129 sg:person.01323700675.54 schema:affiliation https://www.grid.ac/institutes/grid.417520.5
130 schema:familyName Sperduti
131 schema:givenName Isabella
132 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01323700675.54
133 rdf:type schema:Person
134 sg:person.01343325771.54 schema:affiliation https://www.grid.ac/institutes/grid.416308.8
135 schema:familyName Guglielmo
136 schema:givenName Nicola
137 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01343325771.54
138 rdf:type schema:Person
139 sg:person.0611306744.39 schema:affiliation https://www.grid.ac/institutes/grid.416308.8
140 schema:familyName Vennarecci
141 schema:givenName Giovanni
142 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0611306744.39
143 rdf:type schema:Person
144 sg:person.0747272364.59 schema:affiliation https://www.grid.ac/institutes/grid.416308.8
145 schema:familyName Berardi
146 schema:givenName Giammauro
147 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0747272364.59
148 rdf:type schema:Person
149 sg:pub.10.1007/s00268-013-2296-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1046045667
150 https://doi.org/10.1007/s00268-013-2296-y
151 rdf:type schema:CreativeWork
152 sg:pub.10.1007/s00268-013-2401-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035433988
153 https://doi.org/10.1007/s00268-013-2401-2
154 rdf:type schema:CreativeWork
155 sg:pub.10.1007/s00268-014-2513-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046702298
156 https://doi.org/10.1007/s00268-014-2513-3
157 rdf:type schema:CreativeWork
158 sg:pub.10.1007/s11605-012-2029-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014548529
159 https://doi.org/10.1007/s11605-012-2029-9
160 rdf:type schema:CreativeWork
161 sg:pub.10.1007/s11605-012-2092-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029542393
162 https://doi.org/10.1007/s11605-012-2092-2
163 rdf:type schema:CreativeWork
164 sg:pub.10.1007/s13304-016-0401-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008564505
165 https://doi.org/10.1007/s13304-016-0401-0
166 rdf:type schema:CreativeWork
167 sg:pub.10.1007/s13304-017-0481-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1091117074
168 https://doi.org/10.1007/s13304-017-0481-5
169 rdf:type schema:CreativeWork
170 sg:pub.10.1245/s10434-014-4213-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049561328
171 https://doi.org/10.1245/s10434-014-4213-5
172 rdf:type schema:CreativeWork
173 sg:pub.10.1245/s10434-014-4291-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049874261
174 https://doi.org/10.1245/s10434-014-4291-4
175 rdf:type schema:CreativeWork
176 sg:pub.10.1245/s10434-015-5007-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004467227
177 https://doi.org/10.1245/s10434-015-5007-0
178 rdf:type schema:CreativeWork
179 https://doi.org/10.1002/bjs.6756 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043375162
180 rdf:type schema:CreativeWork
181 https://doi.org/10.1002/hep.29086 schema:sameAs https://app.dimensions.ai/details/publication/pub.1074239526
182 rdf:type schema:CreativeWork
183 https://doi.org/10.1016/j.amjsurg.2008.04.022 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030780261
184 rdf:type schema:CreativeWork
185 https://doi.org/10.1016/j.ejso.2015.01.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019154592
186 rdf:type schema:CreativeWork
187 https://doi.org/10.1016/j.hpb.2016.02.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017676777
188 rdf:type schema:CreativeWork
189 https://doi.org/10.1016/j.ijscr.2016.07.039 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039641432
190 rdf:type schema:CreativeWork
191 https://doi.org/10.1016/j.ijsu.2014.11.054 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023197526
192 rdf:type schema:CreativeWork
193 https://doi.org/10.1016/j.ijsu.2016.04.031 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021573241
194 rdf:type schema:CreativeWork
195 https://doi.org/10.1016/j.jamcollsurg.2013.03.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046823217
196 rdf:type schema:CreativeWork
197 https://doi.org/10.1016/j.jhep.2011.12.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051138497
198 rdf:type schema:CreativeWork
199 https://doi.org/10.1016/j.jhep.2016.05.044 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004650844
200 rdf:type schema:CreativeWork
201 https://doi.org/10.1016/s1499-3872(15)60414-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036631073
202 rdf:type schema:CreativeWork
203 https://doi.org/10.1097/01.sla.0000048447.16651.7b schema:sameAs https://app.dimensions.ai/details/publication/pub.1008677963
204 rdf:type schema:CreativeWork
205 https://doi.org/10.1097/01.sla.0000065265.16728.c0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049992611
206 rdf:type schema:CreativeWork
207 https://doi.org/10.1097/sla.0000000000001007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047210883
208 rdf:type schema:CreativeWork
209 https://doi.org/10.1097/sla.0000000000001087 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003288281
210 rdf:type schema:CreativeWork
211 https://doi.org/10.1097/sla.0000000000001272 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029654558
212 rdf:type schema:CreativeWork
213 https://doi.org/10.1097/sla.0b013e31815f6e5b schema:sameAs https://app.dimensions.ai/details/publication/pub.1048452135
214 rdf:type schema:CreativeWork
215 https://doi.org/10.1097/sla.0b013e31824856f5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022177341
216 rdf:type schema:CreativeWork
217 https://doi.org/10.1111/hpb.12386 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013526410
218 rdf:type schema:CreativeWork
219 https://doi.org/10.1111/liv.13491 schema:sameAs https://app.dimensions.ai/details/publication/pub.1085994893
220 rdf:type schema:CreativeWork
221 https://doi.org/10.1177/1553350617697187 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084247553
222 rdf:type schema:CreativeWork
223 https://doi.org/10.18632/oncotarget.21299 schema:sameAs https://app.dimensions.ai/details/publication/pub.1091987381
224 rdf:type schema:CreativeWork
225 https://www.grid.ac/institutes/grid.416308.8 schema:alternateName Ospedale San Camillo
226 schema:name Division of General Surgery and Liver Transplantation, S. Camillo Hospital, Circ.ne Gianicolense 87, 00151, Rome, Italy
227 rdf:type schema:Organization
228 https://www.grid.ac/institutes/grid.417520.5 schema:alternateName Istituti Fisioterapici Ospitalieri
229 schema:name Biostatistical Unit, Regina Elena National Cancer Institute, Rome, Italy
230 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...