Pioglitazone in Clinical Practice: Where Are We Now? View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2012-12

AUTHORS

Joytish Govindan, Marc Evans

ABSTRACT

Pioglitazone, a thiazolidinedione, improves insulin sensitivity and thus reduces blood glucose. Clinical trials have suggested potential cardiovascular outcome benefits in association with pioglitazone; however, safety concerns are mounting, with recent data suggesting a link between pioglitazone and an increased risk of bladder cancer. There is thus a growing focus on the risk-benefit profile of this agent and hence its potential role in the blood glucose-lowering treatment algorithm for people with type 2 diabetes. There are clear potential outcome benefits associated with pioglitazone. In this review, the authors focus on putting the true risk-benefit profile of pioglitazone into context based on critical appraisal of the currently available evidence. More... »

PAGES

1

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s13300-012-0001-z

DOI

http://dx.doi.org/10.1007/s13300-012-0001-z

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1013910257

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/22373598


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