RETRACTED ARTICLE: Overexpression of SphK1 enhances cell proliferation and invasion in triple-negative breast cancer via the PI3K/AKT signaling pathway View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2016-08

AUTHORS

Jun Li, Zhangjun Song, Yiyu Wang, Yue Yin, Ying Liu, Rong Yuan, Xing Nan

ABSTRACT

Sphingosine kinase 1 (SphK1) expression is elevated in various cancers and is associated with shorter survival times for patients. However, the molecular mechanism of SphK1 up-regulation in triple-negative breast cancer (TNBC) remains unclear. In this study, we assayed the expression level of SphK1 in TNBC tissues by qRT-PCR and immunohistochemistry. The level of S1P was quantified by ELISA in the serum of TNBC patients. Our results found that the levels of SphK1 and S1P were significantly increased in TNBC patients compared with normal control. Furthermore, knockdown of SphK1 with siRNA decreased TNBC cell proliferation and inhibited cell migration/invasion. These data suggest that SphK1 has an important role in TNBC and presents an attractive therapeutic target for the treatment for TNBC. More... »

PAGES

10587-10593

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s13277-016-4954-9

DOI

http://dx.doi.org/10.1007/s13277-016-4954-9

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1011956656

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/26857281


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Oncology and Carcinogenesis", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adaptor Proteins, Signal Transducing", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Apoptosis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cell Division", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cell Line, Tumor", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Disease Progression", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Gene Knockdown Techniques", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Lysophospholipids", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neoplasm Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Phosphatidylinositol 3-Kinases", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Proto-Oncogene Proteins c-akt", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "RNA", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "RNA Interference", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "RNA, Small Interfering", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Signal Transduction", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sphingosine", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Triple Negative Breast Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Tumor Stem Cell Assay", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Shaanxi Tumor Hospital", 
          "id": "https://www.grid.ac/institutes/grid.440289.3", 
          "name": [
            "Tumor Research Center, Shaanxi Provincial Tumor Hospital, No. 309 YanTa West Road, 710061, Xi\u2019an, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Li", 
        "givenName": "Jun", 
        "id": "sg:person.010466562761.37", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010466562761.37"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Shaanxi Tumor Hospital", 
          "id": "https://www.grid.ac/institutes/grid.440289.3", 
          "name": [
            "Breast Surgery Center, Shaanxi Provincial Tumor Hospital, 710061, Xi\u2019an, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Song", 
        "givenName": "Zhangjun", 
        "id": "sg:person.014774640335.63", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014774640335.63"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Shaanxi Tumor Hospital", 
          "id": "https://www.grid.ac/institutes/grid.440289.3", 
          "name": [
            "Tumor Research Center, Shaanxi Provincial Tumor Hospital, No. 309 YanTa West Road, 710061, Xi\u2019an, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wang", 
        "givenName": "Yiyu", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Shaanxi Tumor Hospital", 
          "id": "https://www.grid.ac/institutes/grid.440289.3", 
          "name": [
            "Tumor Research Center, Shaanxi Provincial Tumor Hospital, No. 309 YanTa West Road, 710061, Xi\u2019an, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Yin", 
        "givenName": "Yue", 
        "id": "sg:person.016367601335.97", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016367601335.97"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Shaanxi Tumor Hospital", 
          "id": "https://www.grid.ac/institutes/grid.440289.3", 
          "name": [
            "Tumor Research Center, Shaanxi Provincial Tumor Hospital, No. 309 YanTa West Road, 710061, Xi\u2019an, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Liu", 
        "givenName": "Ying", 
        "id": "sg:person.07664530135.83", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07664530135.83"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Shaanxi Tumor Hospital", 
          "id": "https://www.grid.ac/institutes/grid.440289.3", 
          "name": [
            "Tumor Research Center, Shaanxi Provincial Tumor Hospital, No. 309 YanTa West Road, 710061, Xi\u2019an, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Yuan", 
        "givenName": "Rong", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Shaanxi Tumor Hospital", 
          "id": "https://www.grid.ac/institutes/grid.440289.3", 
          "name": [
            "Tumor Research Center, Shaanxi Provincial Tumor Hospital, No. 309 YanTa West Road, 710061, Xi\u2019an, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nan", 
        "givenName": "Xing", 
        "id": "sg:person.014252045361.92", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014252045361.92"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1158/1535-7163.mct-15-0185", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005714497"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3816/cbc.2009.n.005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006637826"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/bcr1636", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009901347", 
          "https://doi.org/10.1186/bcr1636"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/bcr1636", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009901347", 
          "https://doi.org/10.1186/bcr1636"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ctg.2013.21", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009904459", 
          "https://doi.org/10.1038/ctg.2013.21"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.18632/oncotarget.4818", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011555827"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3322/caac.20138", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020626779"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.18632/oncotarget.6023", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022377121"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bbamem.2006.08.007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027534461"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.18632/oncotarget.4335", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030359804"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bst20110602", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030822222"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bst20110602", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030822222"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00384-012-1510-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030903239", 
          "https://doi.org/10.1007/s00384-012-1510-y"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/35021093", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033846543", 
          "https://doi.org/10.1038/35021093"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.18632/oncotarget.6048", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034280136"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ejca.2010.07.053", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036065297"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.18632/oncotarget.6564", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037874402"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bbrc.2015.03.114", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042820119"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2147/ott.s67673", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044115872"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.18632/oncotarget.1874", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045990035"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2005.03.3845", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064204218"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3892/or.2014.3683", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1071533493"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3892/or.2014.3683", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1071533493"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2016-08", 
    "datePublishedReg": "2016-08-01", 
    "description": "Sphingosine kinase 1 (SphK1) expression is elevated in various cancers and is associated with shorter survival times for patients. However, the molecular mechanism of SphK1 up-regulation in triple-negative breast cancer (TNBC) remains unclear. In this study, we assayed the expression level of SphK1 in TNBC tissues by qRT-PCR and immunohistochemistry. The level of S1P was quantified by ELISA in the serum of TNBC patients. Our results found that the levels of SphK1 and S1P were significantly increased in TNBC patients compared with normal control. Furthermore, knockdown of SphK1 with siRNA decreased TNBC cell proliferation and inhibited cell migration/invasion. These data suggest that SphK1 has an important role in TNBC and presents an attractive therapeutic target for the treatment for TNBC. ", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s13277-016-4954-9", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1091981", 
        "issn": [
          "1010-4283", 
          "1423-0380"
        ], 
        "name": "Tumor Biology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "8", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "37"
      }
    ], 
    "name": "RETRACTED ARTICLE: Overexpression of SphK1 enhances cell proliferation and invasion in triple-negative breast cancer via the PI3K/AKT signaling pathway", 
    "pagination": "10587-10593", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "38f7cc96dd8f4da37860578f2bb5b819109ff0291ac65400bb838eff431c31a7"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "26857281"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "8409922"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s13277-016-4954-9"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1011956656"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s13277-016-4954-9", 
      "https://app.dimensions.ai/details/publication/pub.1011956656"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T17:33", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8672_00000520.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007%2Fs13277-016-4954-9"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s13277-016-4954-9'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s13277-016-4954-9'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s13277-016-4954-9'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s13277-016-4954-9'


 

This table displays all metadata directly associated to this object as RDF triples.

250 TRIPLES      21 PREDICATES      68 URIs      40 LITERALS      28 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s13277-016-4954-9 schema:about N120062e7c5934b06932212fb11d8f0f3
2 N1cda3ef756bc4b6b98814366c2c26842
3 N2cf785251e644536846cc3b260e20a48
4 N36508e5a6c964c79b0c11d0c6a4d3735
5 N47e2a3ec368c4894959e62bbc68303bc
6 N59dca792e66e49279e8e1542c6154793
7 N61a30a874ec4474eb213f28e63e9d40b
8 N6c329d2cc7a64fc1891d7bff6088287f
9 N705d77ac9485422386e09211685e276f
10 N72e0ad7598a74c2f89f9daaed07e4ce2
11 N74d82ab68cd94dc3b4a7d064af4dea1f
12 N8ab8fba7eea541078962b46e289b0bb1
13 N8b2ad51377114a09b5f3dd190ff1fb48
14 N91c6268d545a40fab790870907098500
15 N9da2dea958fe4190a85f5e7b023f55b3
16 Na5b19fb566fb4f7396d2cc7e7a485856
17 Nb87eaf2f667d478087a61b7c3252a131
18 Nf028143e24d34effa5b43d87c4ebfe47
19 Nf72e24e3436c416082bc9568a9ace571
20 anzsrc-for:11
21 anzsrc-for:1112
22 schema:author N07a281e856c942a1be8e53ce3518e75a
23 schema:citation sg:pub.10.1007/s00384-012-1510-y
24 sg:pub.10.1038/35021093
25 sg:pub.10.1038/ctg.2013.21
26 sg:pub.10.1186/bcr1636
27 https://doi.org/10.1016/j.bbamem.2006.08.007
28 https://doi.org/10.1016/j.bbrc.2015.03.114
29 https://doi.org/10.1016/j.ejca.2010.07.053
30 https://doi.org/10.1042/bst20110602
31 https://doi.org/10.1158/1535-7163.mct-15-0185
32 https://doi.org/10.1200/jco.2005.03.3845
33 https://doi.org/10.18632/oncotarget.1874
34 https://doi.org/10.18632/oncotarget.4335
35 https://doi.org/10.18632/oncotarget.4818
36 https://doi.org/10.18632/oncotarget.6023
37 https://doi.org/10.18632/oncotarget.6048
38 https://doi.org/10.18632/oncotarget.6564
39 https://doi.org/10.2147/ott.s67673
40 https://doi.org/10.3322/caac.20138
41 https://doi.org/10.3816/cbc.2009.n.005
42 https://doi.org/10.3892/or.2014.3683
43 schema:datePublished 2016-08
44 schema:datePublishedReg 2016-08-01
45 schema:description Sphingosine kinase 1 (SphK1) expression is elevated in various cancers and is associated with shorter survival times for patients. However, the molecular mechanism of SphK1 up-regulation in triple-negative breast cancer (TNBC) remains unclear. In this study, we assayed the expression level of SphK1 in TNBC tissues by qRT-PCR and immunohistochemistry. The level of S1P was quantified by ELISA in the serum of TNBC patients. Our results found that the levels of SphK1 and S1P were significantly increased in TNBC patients compared with normal control. Furthermore, knockdown of SphK1 with siRNA decreased TNBC cell proliferation and inhibited cell migration/invasion. These data suggest that SphK1 has an important role in TNBC and presents an attractive therapeutic target for the treatment for TNBC.
46 schema:genre research_article
47 schema:inLanguage en
48 schema:isAccessibleForFree false
49 schema:isPartOf Na94894a8027a4f4a863b31c1cdc8302b
50 Nc193eb8140814f828c1079f77b3298d9
51 sg:journal.1091981
52 schema:name RETRACTED ARTICLE: Overexpression of SphK1 enhances cell proliferation and invasion in triple-negative breast cancer via the PI3K/AKT signaling pathway
53 schema:pagination 10587-10593
54 schema:productId N180ad0b1c7294a7091004ce74ef46f1e
55 N9a9e634bf95443b5a768b18ed6a98d5d
56 Nd7f4063a0eb5445ea434d58795afdbb1
57 Nea540fa6f36c47148f94b6f04814b683
58 Nf16c76afee7e4847b1ddffea75ac2e73
59 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011956656
60 https://doi.org/10.1007/s13277-016-4954-9
61 schema:sdDatePublished 2019-04-10T17:33
62 schema:sdLicense https://scigraph.springernature.com/explorer/license/
63 schema:sdPublisher N6b88f142173d432d9000b5ea55b8e769
64 schema:url http://link.springer.com/10.1007%2Fs13277-016-4954-9
65 sgo:license sg:explorer/license/
66 sgo:sdDataset articles
67 rdf:type schema:ScholarlyArticle
68 N07a281e856c942a1be8e53ce3518e75a rdf:first sg:person.010466562761.37
69 rdf:rest Ne7570567b3a34114bddaed182d9bd5e6
70 N120062e7c5934b06932212fb11d8f0f3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
71 schema:name Female
72 rdf:type schema:DefinedTerm
73 N180ad0b1c7294a7091004ce74ef46f1e schema:name pubmed_id
74 schema:value 26857281
75 rdf:type schema:PropertyValue
76 N189f94c1126847ab977ab8f6676ee7b5 rdf:first sg:person.07664530135.83
77 rdf:rest N7b0000e5191b4810802fed46d0449e54
78 N1cda3ef756bc4b6b98814366c2c26842 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
79 schema:name Apoptosis
80 rdf:type schema:DefinedTerm
81 N2cf785251e644536846cc3b260e20a48 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
82 schema:name Signal Transduction
83 rdf:type schema:DefinedTerm
84 N36508e5a6c964c79b0c11d0c6a4d3735 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
85 schema:name Adaptor Proteins, Signal Transducing
86 rdf:type schema:DefinedTerm
87 N47e2a3ec368c4894959e62bbc68303bc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
88 schema:name Sphingosine
89 rdf:type schema:DefinedTerm
90 N59dca792e66e49279e8e1542c6154793 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
91 schema:name Tumor Stem Cell Assay
92 rdf:type schema:DefinedTerm
93 N61a30a874ec4474eb213f28e63e9d40b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
94 schema:name Triple Negative Breast Neoplasms
95 rdf:type schema:DefinedTerm
96 N6b88f142173d432d9000b5ea55b8e769 schema:name Springer Nature - SN SciGraph project
97 rdf:type schema:Organization
98 N6c329d2cc7a64fc1891d7bff6088287f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
99 schema:name Cell Line, Tumor
100 rdf:type schema:DefinedTerm
101 N705d77ac9485422386e09211685e276f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
102 schema:name Cell Division
103 rdf:type schema:DefinedTerm
104 N72e0ad7598a74c2f89f9daaed07e4ce2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
105 schema:name Lysophospholipids
106 rdf:type schema:DefinedTerm
107 N74d82ab68cd94dc3b4a7d064af4dea1f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
108 schema:name RNA
109 rdf:type schema:DefinedTerm
110 N7b0000e5191b4810802fed46d0449e54 rdf:first Nb7ad0e07d09f4a518a66803e2693befc
111 rdf:rest N845a590fed7644cb906bebdca8b517a8
112 N816f44179f804b87bed2731d659db2f6 rdf:first N8170b2e13dc445c8846e03dd5fca5352
113 rdf:rest Nef8b34cc67af41d1ae9a52e64c1933aa
114 N8170b2e13dc445c8846e03dd5fca5352 schema:affiliation https://www.grid.ac/institutes/grid.440289.3
115 schema:familyName Wang
116 schema:givenName Yiyu
117 rdf:type schema:Person
118 N845a590fed7644cb906bebdca8b517a8 rdf:first sg:person.014252045361.92
119 rdf:rest rdf:nil
120 N8ab8fba7eea541078962b46e289b0bb1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
121 schema:name Gene Knockdown Techniques
122 rdf:type schema:DefinedTerm
123 N8b2ad51377114a09b5f3dd190ff1fb48 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
124 schema:name Proto-Oncogene Proteins c-akt
125 rdf:type schema:DefinedTerm
126 N91c6268d545a40fab790870907098500 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
127 schema:name RNA, Small Interfering
128 rdf:type schema:DefinedTerm
129 N9a9e634bf95443b5a768b18ed6a98d5d schema:name readcube_id
130 schema:value 38f7cc96dd8f4da37860578f2bb5b819109ff0291ac65400bb838eff431c31a7
131 rdf:type schema:PropertyValue
132 N9da2dea958fe4190a85f5e7b023f55b3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
133 schema:name Neoplasm Proteins
134 rdf:type schema:DefinedTerm
135 Na5b19fb566fb4f7396d2cc7e7a485856 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
136 schema:name Humans
137 rdf:type schema:DefinedTerm
138 Na94894a8027a4f4a863b31c1cdc8302b schema:volumeNumber 37
139 rdf:type schema:PublicationVolume
140 Nb7ad0e07d09f4a518a66803e2693befc schema:affiliation https://www.grid.ac/institutes/grid.440289.3
141 schema:familyName Yuan
142 schema:givenName Rong
143 rdf:type schema:Person
144 Nb87eaf2f667d478087a61b7c3252a131 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
145 schema:name Phosphatidylinositol 3-Kinases
146 rdf:type schema:DefinedTerm
147 Nc193eb8140814f828c1079f77b3298d9 schema:issueNumber 8
148 rdf:type schema:PublicationIssue
149 Nd7f4063a0eb5445ea434d58795afdbb1 schema:name doi
150 schema:value 10.1007/s13277-016-4954-9
151 rdf:type schema:PropertyValue
152 Ne7570567b3a34114bddaed182d9bd5e6 rdf:first sg:person.014774640335.63
153 rdf:rest N816f44179f804b87bed2731d659db2f6
154 Nea540fa6f36c47148f94b6f04814b683 schema:name dimensions_id
155 schema:value pub.1011956656
156 rdf:type schema:PropertyValue
157 Nef8b34cc67af41d1ae9a52e64c1933aa rdf:first sg:person.016367601335.97
158 rdf:rest N189f94c1126847ab977ab8f6676ee7b5
159 Nf028143e24d34effa5b43d87c4ebfe47 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
160 schema:name Disease Progression
161 rdf:type schema:DefinedTerm
162 Nf16c76afee7e4847b1ddffea75ac2e73 schema:name nlm_unique_id
163 schema:value 8409922
164 rdf:type schema:PropertyValue
165 Nf72e24e3436c416082bc9568a9ace571 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
166 schema:name RNA Interference
167 rdf:type schema:DefinedTerm
168 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
169 schema:name Medical and Health Sciences
170 rdf:type schema:DefinedTerm
171 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
172 schema:name Oncology and Carcinogenesis
173 rdf:type schema:DefinedTerm
174 sg:journal.1091981 schema:issn 1010-4283
175 1423-0380
176 schema:name Tumor Biology
177 rdf:type schema:Periodical
178 sg:person.010466562761.37 schema:affiliation https://www.grid.ac/institutes/grid.440289.3
179 schema:familyName Li
180 schema:givenName Jun
181 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010466562761.37
182 rdf:type schema:Person
183 sg:person.014252045361.92 schema:affiliation https://www.grid.ac/institutes/grid.440289.3
184 schema:familyName Nan
185 schema:givenName Xing
186 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014252045361.92
187 rdf:type schema:Person
188 sg:person.014774640335.63 schema:affiliation https://www.grid.ac/institutes/grid.440289.3
189 schema:familyName Song
190 schema:givenName Zhangjun
191 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014774640335.63
192 rdf:type schema:Person
193 sg:person.016367601335.97 schema:affiliation https://www.grid.ac/institutes/grid.440289.3
194 schema:familyName Yin
195 schema:givenName Yue
196 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016367601335.97
197 rdf:type schema:Person
198 sg:person.07664530135.83 schema:affiliation https://www.grid.ac/institutes/grid.440289.3
199 schema:familyName Liu
200 schema:givenName Ying
201 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07664530135.83
202 rdf:type schema:Person
203 sg:pub.10.1007/s00384-012-1510-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1030903239
204 https://doi.org/10.1007/s00384-012-1510-y
205 rdf:type schema:CreativeWork
206 sg:pub.10.1038/35021093 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033846543
207 https://doi.org/10.1038/35021093
208 rdf:type schema:CreativeWork
209 sg:pub.10.1038/ctg.2013.21 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009904459
210 https://doi.org/10.1038/ctg.2013.21
211 rdf:type schema:CreativeWork
212 sg:pub.10.1186/bcr1636 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009901347
213 https://doi.org/10.1186/bcr1636
214 rdf:type schema:CreativeWork
215 https://doi.org/10.1016/j.bbamem.2006.08.007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027534461
216 rdf:type schema:CreativeWork
217 https://doi.org/10.1016/j.bbrc.2015.03.114 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042820119
218 rdf:type schema:CreativeWork
219 https://doi.org/10.1016/j.ejca.2010.07.053 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036065297
220 rdf:type schema:CreativeWork
221 https://doi.org/10.1042/bst20110602 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030822222
222 rdf:type schema:CreativeWork
223 https://doi.org/10.1158/1535-7163.mct-15-0185 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005714497
224 rdf:type schema:CreativeWork
225 https://doi.org/10.1200/jco.2005.03.3845 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064204218
226 rdf:type schema:CreativeWork
227 https://doi.org/10.18632/oncotarget.1874 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045990035
228 rdf:type schema:CreativeWork
229 https://doi.org/10.18632/oncotarget.4335 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030359804
230 rdf:type schema:CreativeWork
231 https://doi.org/10.18632/oncotarget.4818 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011555827
232 rdf:type schema:CreativeWork
233 https://doi.org/10.18632/oncotarget.6023 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022377121
234 rdf:type schema:CreativeWork
235 https://doi.org/10.18632/oncotarget.6048 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034280136
236 rdf:type schema:CreativeWork
237 https://doi.org/10.18632/oncotarget.6564 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037874402
238 rdf:type schema:CreativeWork
239 https://doi.org/10.2147/ott.s67673 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044115872
240 rdf:type schema:CreativeWork
241 https://doi.org/10.3322/caac.20138 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020626779
242 rdf:type schema:CreativeWork
243 https://doi.org/10.3816/cbc.2009.n.005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006637826
244 rdf:type schema:CreativeWork
245 https://doi.org/10.3892/or.2014.3683 schema:sameAs https://app.dimensions.ai/details/publication/pub.1071533493
246 rdf:type schema:CreativeWork
247 https://www.grid.ac/institutes/grid.440289.3 schema:alternateName Shaanxi Tumor Hospital
248 schema:name Breast Surgery Center, Shaanxi Provincial Tumor Hospital, 710061, Xi’an, China
249 Tumor Research Center, Shaanxi Provincial Tumor Hospital, No. 309 YanTa West Road, 710061, Xi’an, China
250 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...