Role of miR-155 in drug resistance of breast cancer View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2015-03

AUTHORS

Dan-dan Yu, Meng-meng Lv, Wei-xian Chen, Shan-liang Zhong, Xiao-hui Zhang, Lin Chen, Teng-fei Ma, Jin-hai Tang, Jian-hua Zhao

ABSTRACT

MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expressions at posttranscriptional level. Growing evidence points to their significant role in the acquisition of drug resistance in cancers. Studies show that miRNAs are often aberrantly expressed in human cancer cells which are associated with tumorigenesis, metastasis, invasiveness, and drug resistance. Breast cancer is the leading cause of cancer-induced death in women. Over the last decades, increasing attention has been paid to the effects of miRNAs on the development of breast cancer drug resistance. Among them, miR-155 takes part in a sequence of bioprocesses that contribute to the development of such drug resistance, including repression of FOXO3a, enhancement of epithelial-to-mesenchymal transition (EMT) and mitogen-activated protein kinase (MAPK) signaling, reduction of RhoA, and affecting the length of telomeres. In this review, we discuss the role of miR-155 in the acquisition of breast cancer drug resistance. This will provide a new way in antiresistance treatment of drug-resistant breast cancer. More... »

PAGES

1395-1401

References to SciGraph publications

  • 2014-12. Oncogenic MicroRNAs: miR-155, miR-19a, miR-181b, and miR-24 enable monitoring of early breast cancer in serum in BMC CANCER
  • 2013-12. MiR-155-mediated loss of C/EBPβ shifts the TGF-β response from growth inhibition to epithelial-mesenchymal transition, invasion and metastasis in breast cancer in ONCOGENE
  • 2014-06. Targeting the MUC1-C oncoprotein downregulates HER2 activation and abrogates trastuzumab resistance in breast cancer cells in ONCOGENE
  • 2012-03. Mouse miRNA-709 directly regulates miRNA-15a/16-1 biogenesis at the posttranscriptional level in the nucleus: evidence for a microRNA hierarchy system in CELL RESEARCH
  • 2008-11. Breast cancer cells with acquired resistance to the EGFR tyrosine kinase inhibitor gefitinib show persistent activation of MAPK signaling in BREAST CANCER RESEARCH AND TREATMENT
  • 2011-12. Consequences of cell-to-cell P-glycoprotein transfer on acquired multidrug resistance in breast cancer: a cell population dynamics model in BIOLOGY DIRECT
  • 2011-08. MicroRNA-mediated drug resistance in breast cancer in CLINICAL EPIGENETICS
  • 2013-06. Mutant p53 drives invasion in breast tumors through up-regulation of miR-155 in ONCOGENE
  • 2009-06. Rho signaling, ROCK and mDia1, in transformation, metastasis and invasion in CANCER AND METASTASIS REVIEWS
  • 2009-04. Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits in NATURE REVIEWS CANCER
  • 2010-08. EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer in ONCOGENE
  • 2011-06. Telomerase expression and telomere length in breast cancer and their associations with adjuvant treatment and disease outcome in BREAST CANCER RESEARCH
  • 2004-10. Reduced expression of p27 is a novel mechanism of docetaxel resistance in breast cancer cells in BREAST CANCER RESEARCH
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s13277-015-3263-z

    DOI

    http://dx.doi.org/10.1007/s13277-015-3263-z

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1011491956

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/25744731


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