RHBDD2: a 5-fluorouracil responsive gene overexpressed in the advanced stages of colorectal cancer View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2012-12

AUTHORS

Ezequiel Lacunza, R. Canzoneri, M. E. Rabassa, A. Zwenger, A. Segal-Eiras, M. V. Croce, M. C. Abba

ABSTRACT

In previous studies, we identified rhomboid domain containing 2 (RHBDD2) gene to be markedly overexpressed in breast cancer patients that developed recurrence of the disease. In this study, we evaluated for the first time RHBDD2 gene expression in colorectal cancer (CRC). Five public available DNA microarray studies were compiled in a homogeneous dataset of 906 colorectal samples. The statistical analysis of these data showed a significant increase of RHBDD2 expression in the advanced stages of CRC (p < 0.01). We validated these findings by immunohistochemistry on 130 colorectal tissue samples; RHBDD2 protein overexpression was also observed in the advanced stages of the disease (p < 0.001). In addition, we investigated RHBDD2 expression in response to the chemotherapy agent 5-fluorouracile (5FU). We detected a significant increase of RHBDD2 mRNA and protein after 5FU treatment (20-40 μM; p < 0.001). Overall, these results showed that RHBDD2 overexpression might play a role in colorectal cancer progression. More... »

PAGES

2393-2399

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s13277-012-0503-3

DOI

http://dx.doi.org/10.1007/s13277-012-0503-3

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1006112854

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/22965880


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Oncology and Carcinogenesis", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Antimetabolites, Antineoplastic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Biomarkers, Tumor", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Blotting, Western", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Case-Control Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Colon", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Colorectal Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Fluorouracil", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Gene Expression Profiling", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Immunoenzyme Techniques", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neoplasm Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neoplasm Staging", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Oligonucleotide Array Sequence Analysis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Prognosis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "RNA, Messenger", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Real-Time Polymerase Chain Reaction", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rectum", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Reverse Transcriptase Polymerase Chain Reaction", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Tumor Cells, Cultured", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "National University of La Plata", 
          "id": "https://www.grid.ac/institutes/grid.9499.d", 
          "name": [
            "CINIBA, Facultad de Ciencias M\u00e9dicas, Universidad Nacional de La Plata, La Plata, Argentina"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lacunza", 
        "givenName": "Ezequiel", 
        "id": "sg:person.01345434622.51", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01345434622.51"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "National University of La Plata", 
          "id": "https://www.grid.ac/institutes/grid.9499.d", 
          "name": [
            "CINIBA, Facultad de Ciencias M\u00e9dicas, Universidad Nacional de La Plata, La Plata, Argentina"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Canzoneri", 
        "givenName": "R.", 
        "id": "sg:person.0622030522.32", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0622030522.32"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "National University of La Plata", 
          "id": "https://www.grid.ac/institutes/grid.9499.d", 
          "name": [
            "CINIBA, Facultad de Ciencias M\u00e9dicas, Universidad Nacional de La Plata, La Plata, Argentina"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rabassa", 
        "givenName": "M. E.", 
        "id": "sg:person.01235302420.03", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01235302420.03"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "National University of La Plata", 
          "id": "https://www.grid.ac/institutes/grid.9499.d", 
          "name": [
            "CINIBA, Facultad de Ciencias M\u00e9dicas, Universidad Nacional de La Plata, La Plata, Argentina", 
            "Hospital Provincial Neuqu\u00e9n \u201cDr Castro Rend\u00f3n\u201d, Servicio de Oncolog\u00eda, Neuqu\u00e9n, Argentina"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Zwenger", 
        "givenName": "A.", 
        "id": "sg:person.0767056552.63", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0767056552.63"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "National University of La Plata", 
          "id": "https://www.grid.ac/institutes/grid.9499.d", 
          "name": [
            "CINIBA, Facultad de Ciencias M\u00e9dicas, Universidad Nacional de La Plata, La Plata, Argentina"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Segal-Eiras", 
        "givenName": "A.", 
        "id": "sg:person.01272765141.17", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01272765141.17"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "National University of La Plata", 
          "id": "https://www.grid.ac/institutes/grid.9499.d", 
          "name": [
            "CINIBA, Facultad de Ciencias M\u00e9dicas, Universidad Nacional de La Plata, La Plata, Argentina"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Croce", 
        "givenName": "M. V.", 
        "id": "sg:person.01126334742.29", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01126334742.29"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "National University of La Plata", 
          "id": "https://www.grid.ac/institutes/grid.9499.d", 
          "name": [
            "CINIBA, Facultad de Ciencias M\u00e9dicas, Universidad Nacional de La Plata, La Plata, Argentina"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Abba", 
        "givenName": "M. C.", 
        "id": "sg:person.0776634066.02", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0776634066.02"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1111/j.1742-4658.2009.07448.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002151122"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.critrevonc.2007.11.005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006316470"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1096/fj.08-112771", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015231999"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4061/2011/932932", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015885247"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0092-8674(01)00526-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018413436"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/0008-5472.can-05-2693", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023481060"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cell.2011.02.013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023540354"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/1541-7786.mcr-07-0055", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030486786"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1146/annurev.genet.42.110807.091628", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030890837"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0092-8674(00)81683-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031899717"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00018-008-8452-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033055346", 
          "https://doi.org/10.1007/s00018-008-8452-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/1078-0432.ccr-09-1431", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035200906"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0092-8674(01)00525-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038235605"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/j.gastro.2009.11.005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043914495"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/1535-7163.mct-08-0104", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045671734"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1038/embor.2011.50", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045805917"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bbadis.2009.07.006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048207264"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1076617338", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2012-12", 
    "datePublishedReg": "2012-12-01", 
    "description": "In previous studies, we identified rhomboid domain containing 2 (RHBDD2) gene to be markedly overexpressed in breast cancer patients that developed recurrence of the disease. In this study, we evaluated for the first time RHBDD2 gene expression in colorectal cancer (CRC). Five public available DNA microarray studies were compiled in a homogeneous dataset of 906 colorectal samples. The statistical analysis of these data showed a significant increase of RHBDD2 expression in the advanced stages of CRC (p < 0.01). We validated these findings by immunohistochemistry on 130 colorectal tissue samples; RHBDD2 protein overexpression was also observed in the advanced stages of the disease (p < 0.001). In addition, we investigated RHBDD2 expression in response to the chemotherapy agent 5-fluorouracile (5FU). We detected a significant increase of RHBDD2 mRNA and protein after 5FU treatment (20-40 \u03bcM; p < 0.001). Overall, these results showed that RHBDD2 overexpression might play a role in colorectal cancer progression.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s13277-012-0503-3", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1091981", 
        "issn": [
          "1010-4283", 
          "1423-0380"
        ], 
        "name": "Tumor Biology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "6", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "33"
      }
    ], 
    "name": "RHBDD2: a 5-fluorouracil responsive gene overexpressed in the advanced stages of colorectal cancer", 
    "pagination": "2393-2399", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "1d1e880407d1a3479558176a5b167a29e83b87c68c480af55f48b286722649a4"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "22965880"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "8409922"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s13277-012-0503-3"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1006112854"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s13277-012-0503-3", 
      "https://app.dimensions.ai/details/publication/pub.1006112854"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T01:09", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8697_00000520.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007%2Fs13277-012-0503-3"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s13277-012-0503-3'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s13277-012-0503-3'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s13277-012-0503-3'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s13277-012-0503-3'


 

This table displays all metadata directly associated to this object as RDF triples.

242 TRIPLES      21 PREDICATES      66 URIs      40 LITERALS      28 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s13277-012-0503-3 schema:about N0f523d19f6d6401b8f74ec0ac6099e77
2 N14875af3ce6f437797435d0e1a3b27ac
3 N18152d8277fa4d70b3d459fe14e83310
4 N34e61515c3404b88b2d53f3fc35c7eed
5 N53b0a98abe58425db2f0b6085084dca6
6 N5b26a2714c35430681de94ab88aa6383
7 N74c66b7640024b509cf945972dbfdd3b
8 N9010b2ba092d4003af6490b8b6f4fb1f
9 Na124e5a5dd1645d58aed3275c4bf5440
10 Naf7b43f4262c49cdbe0e081e123d97ee
11 Nb10ea752528349a88eb951dc41cd18f4
12 Nbbbf9f80e26245df8e5cb00ff735dcca
13 Nc105295f4e24433fba8f9dcf03dd706a
14 Nd9f2f3241fe144089246e3bf4c862955
15 Ndbb7e59688004f348d16053c092e5ca6
16 Nebfce452a0b64b20809b25278c00e6cf
17 Nf1a50808cbc54112a99b7fa4d4ca5c34
18 Nfa658d8ef1864f549449a2683a9ad245
19 Nfff5fd51d3db4b1ea13b487937f5d213
20 anzsrc-for:11
21 anzsrc-for:1112
22 schema:author N0fc60178de964d769c627ff42627a9a8
23 schema:citation sg:pub.10.1007/s00018-008-8452-0
24 https://app.dimensions.ai/details/publication/pub.1076617338
25 https://doi.org/10.1016/j.bbadis.2009.07.006
26 https://doi.org/10.1016/j.cell.2011.02.013
27 https://doi.org/10.1016/j.critrevonc.2007.11.005
28 https://doi.org/10.1016/s0092-8674(00)81683-9
29 https://doi.org/10.1016/s0092-8674(01)00525-6
30 https://doi.org/10.1016/s0092-8674(01)00526-8
31 https://doi.org/10.1038/embor.2011.50
32 https://doi.org/10.1053/j.gastro.2009.11.005
33 https://doi.org/10.1096/fj.08-112771
34 https://doi.org/10.1111/j.1742-4658.2009.07448.x
35 https://doi.org/10.1146/annurev.genet.42.110807.091628
36 https://doi.org/10.1158/0008-5472.can-05-2693
37 https://doi.org/10.1158/1078-0432.ccr-09-1431
38 https://doi.org/10.1158/1535-7163.mct-08-0104
39 https://doi.org/10.1158/1541-7786.mcr-07-0055
40 https://doi.org/10.4061/2011/932932
41 schema:datePublished 2012-12
42 schema:datePublishedReg 2012-12-01
43 schema:description In previous studies, we identified rhomboid domain containing 2 (RHBDD2) gene to be markedly overexpressed in breast cancer patients that developed recurrence of the disease. In this study, we evaluated for the first time RHBDD2 gene expression in colorectal cancer (CRC). Five public available DNA microarray studies were compiled in a homogeneous dataset of 906 colorectal samples. The statistical analysis of these data showed a significant increase of RHBDD2 expression in the advanced stages of CRC (p < 0.01). We validated these findings by immunohistochemistry on 130 colorectal tissue samples; RHBDD2 protein overexpression was also observed in the advanced stages of the disease (p < 0.001). In addition, we investigated RHBDD2 expression in response to the chemotherapy agent 5-fluorouracile (5FU). We detected a significant increase of RHBDD2 mRNA and protein after 5FU treatment (20-40 μM; p < 0.001). Overall, these results showed that RHBDD2 overexpression might play a role in colorectal cancer progression.
44 schema:genre research_article
45 schema:inLanguage en
46 schema:isAccessibleForFree false
47 schema:isPartOf N46f077aef29045d0810d1535888cb059
48 N47b1390e5f1b4620adf85fb704a471fc
49 sg:journal.1091981
50 schema:name RHBDD2: a 5-fluorouracil responsive gene overexpressed in the advanced stages of colorectal cancer
51 schema:pagination 2393-2399
52 schema:productId N1d82cb7d79a14ead80d42450df85180a
53 N2937a8683a5242148198f8e8abcff79f
54 N34d2b8628d2f49ce9fa98b0c9ce79eed
55 N462a0cd991ba4840bb7c1f03b8d016c4
56 Na2e6e311949e4be391508f92111d509c
57 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006112854
58 https://doi.org/10.1007/s13277-012-0503-3
59 schema:sdDatePublished 2019-04-11T01:09
60 schema:sdLicense https://scigraph.springernature.com/explorer/license/
61 schema:sdPublisher N83be747769c0496bbac5b0b7ceddc263
62 schema:url http://link.springer.com/10.1007%2Fs13277-012-0503-3
63 sgo:license sg:explorer/license/
64 sgo:sdDataset articles
65 rdf:type schema:ScholarlyArticle
66 N0f523d19f6d6401b8f74ec0ac6099e77 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
67 schema:name Real-Time Polymerase Chain Reaction
68 rdf:type schema:DefinedTerm
69 N0fc60178de964d769c627ff42627a9a8 rdf:first sg:person.01345434622.51
70 rdf:rest Nc0f5f42fd4414fe89c49b324212bfe6c
71 N14875af3ce6f437797435d0e1a3b27ac schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
72 schema:name Prognosis
73 rdf:type schema:DefinedTerm
74 N18152d8277fa4d70b3d459fe14e83310 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
75 schema:name Neoplasm Proteins
76 rdf:type schema:DefinedTerm
77 N193d431b5f1f44fc9c3f0cabe7a90fd2 rdf:first sg:person.0776634066.02
78 rdf:rest rdf:nil
79 N1d82cb7d79a14ead80d42450df85180a schema:name nlm_unique_id
80 schema:value 8409922
81 rdf:type schema:PropertyValue
82 N2937a8683a5242148198f8e8abcff79f schema:name readcube_id
83 schema:value 1d1e880407d1a3479558176a5b167a29e83b87c68c480af55f48b286722649a4
84 rdf:type schema:PropertyValue
85 N34d2b8628d2f49ce9fa98b0c9ce79eed schema:name doi
86 schema:value 10.1007/s13277-012-0503-3
87 rdf:type schema:PropertyValue
88 N34e61515c3404b88b2d53f3fc35c7eed schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
89 schema:name Biomarkers, Tumor
90 rdf:type schema:DefinedTerm
91 N3fdb487c1b8140aaa2aa331d7a1d6169 rdf:first sg:person.01272765141.17
92 rdf:rest N9eeafb7976a64bcb88b6e91cbe84dd37
93 N462a0cd991ba4840bb7c1f03b8d016c4 schema:name dimensions_id
94 schema:value pub.1006112854
95 rdf:type schema:PropertyValue
96 N46f077aef29045d0810d1535888cb059 schema:volumeNumber 33
97 rdf:type schema:PublicationVolume
98 N47b1390e5f1b4620adf85fb704a471fc schema:issueNumber 6
99 rdf:type schema:PublicationIssue
100 N53b0a98abe58425db2f0b6085084dca6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
101 schema:name Neoplasm Staging
102 rdf:type schema:DefinedTerm
103 N5b26a2714c35430681de94ab88aa6383 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
104 schema:name Colon
105 rdf:type schema:DefinedTerm
106 N74c66b7640024b509cf945972dbfdd3b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
107 schema:name Oligonucleotide Array Sequence Analysis
108 rdf:type schema:DefinedTerm
109 N83be747769c0496bbac5b0b7ceddc263 schema:name Springer Nature - SN SciGraph project
110 rdf:type schema:Organization
111 N9010b2ba092d4003af6490b8b6f4fb1f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
112 schema:name Fluorouracil
113 rdf:type schema:DefinedTerm
114 N90d227e25e9344f2bc126cd1118362de rdf:first sg:person.0767056552.63
115 rdf:rest N3fdb487c1b8140aaa2aa331d7a1d6169
116 N9eeafb7976a64bcb88b6e91cbe84dd37 rdf:first sg:person.01126334742.29
117 rdf:rest N193d431b5f1f44fc9c3f0cabe7a90fd2
118 Na124e5a5dd1645d58aed3275c4bf5440 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
119 schema:name Tumor Cells, Cultured
120 rdf:type schema:DefinedTerm
121 Na2e6e311949e4be391508f92111d509c schema:name pubmed_id
122 schema:value 22965880
123 rdf:type schema:PropertyValue
124 Naf7b43f4262c49cdbe0e081e123d97ee schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
125 schema:name Colorectal Neoplasms
126 rdf:type schema:DefinedTerm
127 Nb10ea752528349a88eb951dc41cd18f4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
128 schema:name Reverse Transcriptase Polymerase Chain Reaction
129 rdf:type schema:DefinedTerm
130 Nb65ee8bc60494d56a2348e777b611f41 rdf:first sg:person.01235302420.03
131 rdf:rest N90d227e25e9344f2bc126cd1118362de
132 Nbbbf9f80e26245df8e5cb00ff735dcca schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
133 schema:name Immunoenzyme Techniques
134 rdf:type schema:DefinedTerm
135 Nc0f5f42fd4414fe89c49b324212bfe6c rdf:first sg:person.0622030522.32
136 rdf:rest Nb65ee8bc60494d56a2348e777b611f41
137 Nc105295f4e24433fba8f9dcf03dd706a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
138 schema:name Humans
139 rdf:type schema:DefinedTerm
140 Nd9f2f3241fe144089246e3bf4c862955 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
141 schema:name Case-Control Studies
142 rdf:type schema:DefinedTerm
143 Ndbb7e59688004f348d16053c092e5ca6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
144 schema:name Blotting, Western
145 rdf:type schema:DefinedTerm
146 Nebfce452a0b64b20809b25278c00e6cf schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
147 schema:name Antimetabolites, Antineoplastic
148 rdf:type schema:DefinedTerm
149 Nf1a50808cbc54112a99b7fa4d4ca5c34 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
150 schema:name Gene Expression Profiling
151 rdf:type schema:DefinedTerm
152 Nfa658d8ef1864f549449a2683a9ad245 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
153 schema:name RNA, Messenger
154 rdf:type schema:DefinedTerm
155 Nfff5fd51d3db4b1ea13b487937f5d213 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
156 schema:name Rectum
157 rdf:type schema:DefinedTerm
158 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
159 schema:name Medical and Health Sciences
160 rdf:type schema:DefinedTerm
161 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
162 schema:name Oncology and Carcinogenesis
163 rdf:type schema:DefinedTerm
164 sg:journal.1091981 schema:issn 1010-4283
165 1423-0380
166 schema:name Tumor Biology
167 rdf:type schema:Periodical
168 sg:person.01126334742.29 schema:affiliation https://www.grid.ac/institutes/grid.9499.d
169 schema:familyName Croce
170 schema:givenName M. V.
171 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01126334742.29
172 rdf:type schema:Person
173 sg:person.01235302420.03 schema:affiliation https://www.grid.ac/institutes/grid.9499.d
174 schema:familyName Rabassa
175 schema:givenName M. E.
176 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01235302420.03
177 rdf:type schema:Person
178 sg:person.01272765141.17 schema:affiliation https://www.grid.ac/institutes/grid.9499.d
179 schema:familyName Segal-Eiras
180 schema:givenName A.
181 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01272765141.17
182 rdf:type schema:Person
183 sg:person.01345434622.51 schema:affiliation https://www.grid.ac/institutes/grid.9499.d
184 schema:familyName Lacunza
185 schema:givenName Ezequiel
186 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01345434622.51
187 rdf:type schema:Person
188 sg:person.0622030522.32 schema:affiliation https://www.grid.ac/institutes/grid.9499.d
189 schema:familyName Canzoneri
190 schema:givenName R.
191 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0622030522.32
192 rdf:type schema:Person
193 sg:person.0767056552.63 schema:affiliation https://www.grid.ac/institutes/grid.9499.d
194 schema:familyName Zwenger
195 schema:givenName A.
196 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0767056552.63
197 rdf:type schema:Person
198 sg:person.0776634066.02 schema:affiliation https://www.grid.ac/institutes/grid.9499.d
199 schema:familyName Abba
200 schema:givenName M. C.
201 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0776634066.02
202 rdf:type schema:Person
203 sg:pub.10.1007/s00018-008-8452-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033055346
204 https://doi.org/10.1007/s00018-008-8452-0
205 rdf:type schema:CreativeWork
206 https://app.dimensions.ai/details/publication/pub.1076617338 schema:CreativeWork
207 https://doi.org/10.1016/j.bbadis.2009.07.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048207264
208 rdf:type schema:CreativeWork
209 https://doi.org/10.1016/j.cell.2011.02.013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023540354
210 rdf:type schema:CreativeWork
211 https://doi.org/10.1016/j.critrevonc.2007.11.005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006316470
212 rdf:type schema:CreativeWork
213 https://doi.org/10.1016/s0092-8674(00)81683-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031899717
214 rdf:type schema:CreativeWork
215 https://doi.org/10.1016/s0092-8674(01)00525-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038235605
216 rdf:type schema:CreativeWork
217 https://doi.org/10.1016/s0092-8674(01)00526-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018413436
218 rdf:type schema:CreativeWork
219 https://doi.org/10.1038/embor.2011.50 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045805917
220 rdf:type schema:CreativeWork
221 https://doi.org/10.1053/j.gastro.2009.11.005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043914495
222 rdf:type schema:CreativeWork
223 https://doi.org/10.1096/fj.08-112771 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015231999
224 rdf:type schema:CreativeWork
225 https://doi.org/10.1111/j.1742-4658.2009.07448.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1002151122
226 rdf:type schema:CreativeWork
227 https://doi.org/10.1146/annurev.genet.42.110807.091628 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030890837
228 rdf:type schema:CreativeWork
229 https://doi.org/10.1158/0008-5472.can-05-2693 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023481060
230 rdf:type schema:CreativeWork
231 https://doi.org/10.1158/1078-0432.ccr-09-1431 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035200906
232 rdf:type schema:CreativeWork
233 https://doi.org/10.1158/1535-7163.mct-08-0104 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045671734
234 rdf:type schema:CreativeWork
235 https://doi.org/10.1158/1541-7786.mcr-07-0055 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030486786
236 rdf:type schema:CreativeWork
237 https://doi.org/10.4061/2011/932932 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015885247
238 rdf:type schema:CreativeWork
239 https://www.grid.ac/institutes/grid.9499.d schema:alternateName National University of La Plata
240 schema:name CINIBA, Facultad de Ciencias Médicas, Universidad Nacional de La Plata, La Plata, Argentina
241 Hospital Provincial Neuquén “Dr Castro Rendón”, Servicio de Oncología, Neuquén, Argentina
242 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...