Ontology type: schema:ScholarlyArticle
2019-03
AUTHORSHong Nam Kim, Nakwon Choi
ABSTRACTTo present a more physiologically relevant microenvironment for cells, hydrogel-based threedimensional culture platforms have been widely adopted. As noted by multiple pioneering reports, the neural cells are sensitive with the change of mechanical properties of the microenvironment. Therefore, in the context of brain tissue engineering and brain-on-a-chip, there is a need to consider the brain-tissue-specific mechanical properties of hydrogels. In this review, we overview the influence the mechanical properties of hydrogel on the behavior of brain tissue cells. For this purpose, in addition to the stiffness, the viscoelasticity and degradability of hydrogels are considered to be mechanical cues, and we summarize how those mechanical properties can affect cell behavior, such as viability, proliferation, differentiation, and spreading. Consideration of the brain tissue-specific mechanical microenvironment may guide the design of 3D cell culture platforms for brain tissue engineering and brain- on-a-chip. More... »
PAGES8-19
http://scigraph.springernature.com/pub.10.1007/s13206-018-3101-7
DOIhttp://dx.doi.org/10.1007/s13206-018-3101-7
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]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1007/s13206-018-3101-7"
]
},
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1112634523"
]
}
],
"sameAs": [
"https://doi.org/10.1007/s13206-018-3101-7",
"https://app.dimensions.ai/details/publication/pub.1112634523"
],
"sdDataset": "articles",
"sdDatePublished": "2019-04-11T12:54",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000364_0000000364/records_72862_00000001.jsonl",
"type": "ScholarlyArticle",
"url": "https://link.springer.com/10.1007%2Fs13206-018-3101-7"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s13206-018-3101-7'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s13206-018-3101-7'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s13206-018-3101-7'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s13206-018-3101-7'
This table displays all metadata directly associated to this object as RDF triples.
300 TRIPLES
21 PREDICATES
99 URIs
19 LITERALS
7 BLANK NODES