The Initial Indian Experience with Cytoreductive Surgery and HIPEC in the Treatment of Peritoneal Metastases View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2016-06

AUTHORS

Aditi Bhatt, Sanket Mehta, Ramakrishnan Ayloor Seshadri, Kayomarz Sethna, Shabber Zaveri, Firoz Rajan, Vikas Mahajan, Shivendra Singh, E. Hemanth Raj, Paul H. Sugarbaker

ABSTRACT

Worldwide, cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) has been used for nearly 3 decades to treat peritoneal metastases (PM), improve quality of life, and prolong survival substantially in selected patients. In India, the use of the combined modality of treatment dates back a decade with majority of the efforts taking place within the last 5 years. The first PSOGI workshop (India) held in April 2015, at Bangalore, India offered an opportunity for Indian surgeons performing CRS and HIPEC to share their experience. To study the methodologies of CRS and HIPEC (hospital set up, equipment, training and surgical background) as well as the outcomes in terms of perioperative morbidity and mortality and short and long term survival of patients treated in India, Indian surgeons who had treated at least 10 patients with this combined modality were invited to present their experience. Data collection was retrospective. Analysis of the pooled data was carried out. Eight surgeons treated 384 patients with CRS and HIPEC over a period of 10 years. The commonest primary sites were ovary (as first line therapy n = 124), followed by appendix, including pseudomyxoma peritonei (n = 99), colorectum (n = 77), recurrent ovary (as second line therapy, n = 33), stomach (n = 15), primary peritoneal cancer (n = 10), peritoneal mesothelioma (n = 9) and rare tumors in 17 patients. The weighted mean PCI for all 384 patients was 18.25. 349/384 patients (90.88 %) had a complete cytoreduction (completeness of cytoreduction score of CC-0/1). Grade 3-5 complications developed in 108 patients (27.34 %) and 30 day mortality occurred in 28 (7.29 %) patients. This study showed that CRS and HIPEC can be performed with an acceptable morbidity and mortality in Indian patients. Most of the surgeons are on the learning curve and further improvement in these outcomes is expected over a period of time. Pooling of data related to both common and rare peritoneal cancers would be useful in knowing the disease behavior, response to treatment and outcomes in Indian patients. The 2015 PSOGI meeting provided a unique platform for data presentation with feedback from international experts in the field of peritoneal surface oncology. Future meetings are planned to expand the evaluation of Indian data and progress. More... »

PAGES

160-165

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s13193-016-0500-x

DOI

http://dx.doi.org/10.1007/s13193-016-0500-x

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1039112428

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/27065706


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Oncology and Carcinogenesis", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Fortis Hospital", 
          "id": "https://www.grid.ac/institutes/grid.417968.5", 
          "name": [
            "Department of Surgical Oncology, Fortis Hospital, 154/9 Bannerghatta road, Opposite IIM-Bangalore, -560076, Bangalore, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bhatt", 
        "givenName": "Aditi", 
        "id": "sg:person.01074632145.26", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01074632145.26"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Saifee Hospital", 
          "id": "https://www.grid.ac/institutes/grid.416467.6", 
          "name": [
            "Department of Surgical Oncology, Saifee Hospital, Mumbai, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mehta", 
        "givenName": "Sanket", 
        "id": "sg:person.0750376105.88", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0750376105.88"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Cancer Institute", 
          "id": "https://www.grid.ac/institutes/grid.418600.b", 
          "name": [
            "Department of Surgical Oncology, Cancer Institute (WIA), Chennai, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Seshadri", 
        "givenName": "Ramakrishnan Ayloor", 
        "id": "sg:person.01127146634.35", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01127146634.35"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of General Sugery, Sion Hospital Mumbai, Mumbai, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sethna", 
        "givenName": "Kayomarz", 
        "id": "sg:person.01070465605.44", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01070465605.44"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Manipal Hospital", 
          "id": "https://www.grid.ac/institutes/grid.416383.b", 
          "name": [
            "Department of Surgical Oncology, Manipal Hospital, Bangalore, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Zaveri", 
        "givenName": "Shabber", 
        "id": "sg:person.0612442642.09", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0612442642.09"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Surgical Oncology, Kovai Medical Centre, Coimbatore, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rajan", 
        "givenName": "Firoz", 
        "id": "sg:person.01122023460.69", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01122023460.69"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Apollo Hospitals", 
          "id": "https://www.grid.ac/institutes/grid.413839.4", 
          "name": [
            "Department of Surgical Oncology, Apollo Hospital, Chennai, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mahajan", 
        "givenName": "Vikas", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of GI Oncology, Rajiv Gandhi Cancer Centre, New Delhi, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Singh", 
        "givenName": "Shivendra", 
        "id": "sg:person.01321142605.72", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01321142605.72"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Cancer Institute", 
          "id": "https://www.grid.ac/institutes/grid.418600.b", 
          "name": [
            "Department of Surgical Oncology, Cancer Institute (WIA), Chennai, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Raj", 
        "givenName": "E. Hemanth", 
        "id": "sg:person.01033151057.16", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01033151057.16"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "MedStar Washington Hospital Center", 
          "id": "https://www.grid.ac/institutes/grid.415235.4", 
          "name": [
            "Washington Cancer Institute, MedStar Washington Hospital Center, Washington, DC, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sugarbaker", 
        "givenName": "Paul H.", 
        "id": "sg:person.014474321717.64", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014474321717.64"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.3747/co.22.2058", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004902730"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3747/co.v18i2.663", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006346070"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000658-199501000-00004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007603247"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000658-199501000-00004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007603247"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cncr.25356", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008199995"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cncr.25356", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008199995"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1245/s10434-015-4387-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011189090", 
          "https://doi.org/10.1245/s10434-015-4387-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2009.23.9285", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011683692"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1245/s10434-011-1631-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012489432", 
          "https://doi.org/10.1245/s10434-011-1631-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ejso.2013.09.030", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016839273"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sla.0b013e3181a45d86", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019299634"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sla.0b013e3181a45d86", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019299634"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sla.0b013e3181a45d86", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019299634"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2009.23.9640", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019587384"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1471-2407-14-183", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019880515", 
          "https://doi.org/10.1186/1471-2407-14-183"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/ppo.0b013e3181a58d56", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025819247"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/ppo.0b013e3181a58d56", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025819247"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/ppo.0b013e3181a58d56", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025819247"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1245/s10434-008-9966-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030091417", 
          "https://doi.org/10.1245/s10434-008-9966-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ejso.2006.03.005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036950189"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/bjs.5863", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037471832"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2007.11.0833", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037561935"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1245/s10434-010-1039-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050112795", 
          "https://doi.org/10.1245/s10434-010-1039-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1245/s10434-010-1039-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050112795", 
          "https://doi.org/10.1245/s10434-010-1039-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ejso.2010.05.007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050171543"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ejca.2013.09.024", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050471755"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sla.0b013e31827e9289", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052087597"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sla.0b013e31827e9289", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052087597"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2011.39.7166", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053361244"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/igc.0b013e3181c50cde", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1061838188"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/igc.0b013e3181c50cde", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1061838188"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/igc.0b013e3181c50cde", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1061838188"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/igc.0b013e3181c50cde", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1061838188"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/igc.0b013e3181c50cde", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1061838188"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2174/138161212802002616", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1069168242"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2016-06", 
    "datePublishedReg": "2016-06-01", 
    "description": "Worldwide, cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) has been used for nearly 3 decades to treat peritoneal metastases (PM), improve quality of life, and prolong survival substantially in selected patients. In India, the use of the combined modality of treatment dates back a decade with majority of the efforts taking place within the last 5\u00a0years. The first PSOGI workshop (India) held in April 2015, at Bangalore, India offered an opportunity for Indian surgeons performing CRS and HIPEC to share their experience. To study the methodologies of CRS and HIPEC (hospital set up, equipment, training and surgical background) as well as the outcomes in terms of perioperative morbidity and mortality and short and long term survival of patients treated in India, Indian surgeons who had treated at least 10 patients with this combined modality were invited to present their experience. Data collection was retrospective. Analysis of the pooled data was carried out. Eight surgeons treated 384 patients with CRS and HIPEC over a period of 10\u00a0years. The commonest primary sites were ovary (as first line therapy n\u00a0=\u00a0124), followed by appendix, including pseudomyxoma peritonei (n\u00a0=\u00a099), colorectum (n\u00a0=\u00a077), recurrent ovary (as second line therapy, n\u00a0=\u00a033), stomach (n\u00a0=\u00a015), primary peritoneal cancer (n\u00a0=\u00a010), peritoneal mesothelioma (n\u00a0=\u00a09) and rare tumors in 17 patients. The weighted mean PCI for all 384 patients was 18.25. 349/384 patients (90.88\u00a0%) had a complete cytoreduction (completeness of cytoreduction score of CC-0/1). Grade 3-5 complications developed in 108 patients (27.34\u00a0%) and 30\u00a0day mortality occurred in 28 (7.29\u00a0%) patients. This study showed that CRS and HIPEC can be performed with an acceptable morbidity and mortality in Indian patients. Most of the surgeons are on the learning curve and further improvement in these outcomes is expected over a period of time. Pooling of data related to both common and rare peritoneal cancers would be useful in knowing the disease behavior, response to treatment and outcomes in Indian patients. The 2015 PSOGI meeting provided a unique platform for data presentation with feedback from international experts in the field of peritoneal surface oncology. Future meetings are planned to expand the evaluation of Indian data and progress. ", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s13193-016-0500-x", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1043605", 
        "issn": [
          "0975-7651", 
          "0976-6952"
        ], 
        "name": "Indian Journal of Surgical Oncology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "2", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "7"
      }
    ], 
    "name": "The Initial Indian Experience with Cytoreductive Surgery and HIPEC in the Treatment of Peritoneal Metastases", 
    "pagination": "160-165", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "ba4fcd4ae14500b7c82093c5331171db039fe81ff48f069ddd14eb6dc7100615"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "27065706"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101532448"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s13193-016-0500-x"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1039112428"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s13193-016-0500-x", 
      "https://app.dimensions.ai/details/publication/pub.1039112428"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T13:20", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8659_00000523.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007%2Fs13193-016-0500-x"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s13193-016-0500-x'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s13193-016-0500-x'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s13193-016-0500-x'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s13193-016-0500-x'


 

This table displays all metadata directly associated to this object as RDF triples.

226 TRIPLES      21 PREDICATES      52 URIs      21 LITERALS      9 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s13193-016-0500-x schema:about anzsrc-for:11
2 anzsrc-for:1112
3 schema:author N3bd0f3a60a64422c9db8e5d18a99dc96
4 schema:citation sg:pub.10.1186/1471-2407-14-183
5 sg:pub.10.1245/s10434-008-9966-2
6 sg:pub.10.1245/s10434-010-1039-7
7 sg:pub.10.1245/s10434-011-1631-5
8 sg:pub.10.1245/s10434-015-4387-5
9 https://doi.org/10.1002/bjs.5863
10 https://doi.org/10.1002/cncr.25356
11 https://doi.org/10.1016/j.ejca.2013.09.024
12 https://doi.org/10.1016/j.ejso.2006.03.005
13 https://doi.org/10.1016/j.ejso.2010.05.007
14 https://doi.org/10.1016/j.ejso.2013.09.030
15 https://doi.org/10.1097/00000658-199501000-00004
16 https://doi.org/10.1097/ppo.0b013e3181a58d56
17 https://doi.org/10.1097/sla.0b013e3181a45d86
18 https://doi.org/10.1097/sla.0b013e31827e9289
19 https://doi.org/10.1111/igc.0b013e3181c50cde
20 https://doi.org/10.1200/jco.2007.11.0833
21 https://doi.org/10.1200/jco.2009.23.9285
22 https://doi.org/10.1200/jco.2009.23.9640
23 https://doi.org/10.1200/jco.2011.39.7166
24 https://doi.org/10.2174/138161212802002616
25 https://doi.org/10.3747/co.22.2058
26 https://doi.org/10.3747/co.v18i2.663
27 schema:datePublished 2016-06
28 schema:datePublishedReg 2016-06-01
29 schema:description Worldwide, cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) has been used for nearly 3 decades to treat peritoneal metastases (PM), improve quality of life, and prolong survival substantially in selected patients. In India, the use of the combined modality of treatment dates back a decade with majority of the efforts taking place within the last 5 years. The first PSOGI workshop (India) held in April 2015, at Bangalore, India offered an opportunity for Indian surgeons performing CRS and HIPEC to share their experience. To study the methodologies of CRS and HIPEC (hospital set up, equipment, training and surgical background) as well as the outcomes in terms of perioperative morbidity and mortality and short and long term survival of patients treated in India, Indian surgeons who had treated at least 10 patients with this combined modality were invited to present their experience. Data collection was retrospective. Analysis of the pooled data was carried out. Eight surgeons treated 384 patients with CRS and HIPEC over a period of 10 years. The commonest primary sites were ovary (as first line therapy n = 124), followed by appendix, including pseudomyxoma peritonei (n = 99), colorectum (n = 77), recurrent ovary (as second line therapy, n = 33), stomach (n = 15), primary peritoneal cancer (n = 10), peritoneal mesothelioma (n = 9) and rare tumors in 17 patients. The weighted mean PCI for all 384 patients was 18.25. 349/384 patients (90.88 %) had a complete cytoreduction (completeness of cytoreduction score of CC-0/1). Grade 3-5 complications developed in 108 patients (27.34 %) and 30 day mortality occurred in 28 (7.29 %) patients. This study showed that CRS and HIPEC can be performed with an acceptable morbidity and mortality in Indian patients. Most of the surgeons are on the learning curve and further improvement in these outcomes is expected over a period of time. Pooling of data related to both common and rare peritoneal cancers would be useful in knowing the disease behavior, response to treatment and outcomes in Indian patients. The 2015 PSOGI meeting provided a unique platform for data presentation with feedback from international experts in the field of peritoneal surface oncology. Future meetings are planned to expand the evaluation of Indian data and progress.
30 schema:genre research_article
31 schema:inLanguage en
32 schema:isAccessibleForFree true
33 schema:isPartOf N84bb184c9011423786275659d9767828
34 Nb6891648bde24da38e512ae4515d2860
35 sg:journal.1043605
36 schema:name The Initial Indian Experience with Cytoreductive Surgery and HIPEC in the Treatment of Peritoneal Metastases
37 schema:pagination 160-165
38 schema:productId N0b1ec31cb1904f4994a9790cf90d3b14
39 N193b238839654c539edcf912a9cf34fd
40 N5fa3f45a9cd94c44bdb632b8da07bfd7
41 N844ff02d94104045824a358c533fe915
42 Nd82c50e7c6f449fc82a1f5b93168ad2a
43 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039112428
44 https://doi.org/10.1007/s13193-016-0500-x
45 schema:sdDatePublished 2019-04-10T13:20
46 schema:sdLicense https://scigraph.springernature.com/explorer/license/
47 schema:sdPublisher N38840e9c82e8469985891a9e8129dfdd
48 schema:url http://link.springer.com/10.1007%2Fs13193-016-0500-x
49 sgo:license sg:explorer/license/
50 sgo:sdDataset articles
51 rdf:type schema:ScholarlyArticle
52 N0b1ec31cb1904f4994a9790cf90d3b14 schema:name readcube_id
53 schema:value ba4fcd4ae14500b7c82093c5331171db039fe81ff48f069ddd14eb6dc7100615
54 rdf:type schema:PropertyValue
55 N193b238839654c539edcf912a9cf34fd schema:name pubmed_id
56 schema:value 27065706
57 rdf:type schema:PropertyValue
58 N1c384b5f8f104b7a98565ea86b5113fb schema:name Department of General Sugery, Sion Hospital Mumbai, Mumbai, India
59 rdf:type schema:Organization
60 N2ac0bf7739b84ef48fec7a3db9f10df1 rdf:first sg:person.01127146634.35
61 rdf:rest N96657b2753fd4cac98de393eb5759e6f
62 N38840e9c82e8469985891a9e8129dfdd schema:name Springer Nature - SN SciGraph project
63 rdf:type schema:Organization
64 N39d5e730373e4c36af8e49c9bb386b6c schema:affiliation https://www.grid.ac/institutes/grid.413839.4
65 schema:familyName Mahajan
66 schema:givenName Vikas
67 rdf:type schema:Person
68 N3bd0f3a60a64422c9db8e5d18a99dc96 rdf:first sg:person.01074632145.26
69 rdf:rest Nda3a385b3ba449e4946ffe24adad04ec
70 N5fa3f45a9cd94c44bdb632b8da07bfd7 schema:name doi
71 schema:value 10.1007/s13193-016-0500-x
72 rdf:type schema:PropertyValue
73 N844ff02d94104045824a358c533fe915 schema:name dimensions_id
74 schema:value pub.1039112428
75 rdf:type schema:PropertyValue
76 N84bb184c9011423786275659d9767828 schema:issueNumber 2
77 rdf:type schema:PublicationIssue
78 N908d770d576c465cbcba2a7fa621ff21 schema:name Department of GI Oncology, Rajiv Gandhi Cancer Centre, New Delhi, India
79 rdf:type schema:Organization
80 N96657b2753fd4cac98de393eb5759e6f rdf:first sg:person.01070465605.44
81 rdf:rest Nbfab2f78e2d14efb8de282a2b7508240
82 N9bbb55182aad4e96a7b5ddf34852f071 rdf:first sg:person.01321142605.72
83 rdf:rest Ne9628b5dc43f45d19c6cdb3b947be967
84 Na9d6cbdfb7014ec0afcebcff93d63c6f rdf:first sg:person.014474321717.64
85 rdf:rest rdf:nil
86 Nb6891648bde24da38e512ae4515d2860 schema:volumeNumber 7
87 rdf:type schema:PublicationVolume
88 Nbd88c18832234591baeb1c7c866f198f rdf:first N39d5e730373e4c36af8e49c9bb386b6c
89 rdf:rest N9bbb55182aad4e96a7b5ddf34852f071
90 Nbfab2f78e2d14efb8de282a2b7508240 rdf:first sg:person.0612442642.09
91 rdf:rest Ne90ec189e7ca47b5b0e646e6c181e427
92 Nd82c50e7c6f449fc82a1f5b93168ad2a schema:name nlm_unique_id
93 schema:value 101532448
94 rdf:type schema:PropertyValue
95 Nda3a385b3ba449e4946ffe24adad04ec rdf:first sg:person.0750376105.88
96 rdf:rest N2ac0bf7739b84ef48fec7a3db9f10df1
97 Ne90ec189e7ca47b5b0e646e6c181e427 rdf:first sg:person.01122023460.69
98 rdf:rest Nbd88c18832234591baeb1c7c866f198f
99 Ne9628b5dc43f45d19c6cdb3b947be967 rdf:first sg:person.01033151057.16
100 rdf:rest Na9d6cbdfb7014ec0afcebcff93d63c6f
101 Ned9971e76b9b4d369ba05f789e8876b7 schema:name Department of Surgical Oncology, Kovai Medical Centre, Coimbatore, India
102 rdf:type schema:Organization
103 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
104 schema:name Medical and Health Sciences
105 rdf:type schema:DefinedTerm
106 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
107 schema:name Oncology and Carcinogenesis
108 rdf:type schema:DefinedTerm
109 sg:journal.1043605 schema:issn 0975-7651
110 0976-6952
111 schema:name Indian Journal of Surgical Oncology
112 rdf:type schema:Periodical
113 sg:person.01033151057.16 schema:affiliation https://www.grid.ac/institutes/grid.418600.b
114 schema:familyName Raj
115 schema:givenName E. Hemanth
116 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01033151057.16
117 rdf:type schema:Person
118 sg:person.01070465605.44 schema:affiliation N1c384b5f8f104b7a98565ea86b5113fb
119 schema:familyName Sethna
120 schema:givenName Kayomarz
121 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01070465605.44
122 rdf:type schema:Person
123 sg:person.01074632145.26 schema:affiliation https://www.grid.ac/institutes/grid.417968.5
124 schema:familyName Bhatt
125 schema:givenName Aditi
126 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01074632145.26
127 rdf:type schema:Person
128 sg:person.01122023460.69 schema:affiliation Ned9971e76b9b4d369ba05f789e8876b7
129 schema:familyName Rajan
130 schema:givenName Firoz
131 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01122023460.69
132 rdf:type schema:Person
133 sg:person.01127146634.35 schema:affiliation https://www.grid.ac/institutes/grid.418600.b
134 schema:familyName Seshadri
135 schema:givenName Ramakrishnan Ayloor
136 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01127146634.35
137 rdf:type schema:Person
138 sg:person.01321142605.72 schema:affiliation N908d770d576c465cbcba2a7fa621ff21
139 schema:familyName Singh
140 schema:givenName Shivendra
141 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01321142605.72
142 rdf:type schema:Person
143 sg:person.014474321717.64 schema:affiliation https://www.grid.ac/institutes/grid.415235.4
144 schema:familyName Sugarbaker
145 schema:givenName Paul H.
146 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014474321717.64
147 rdf:type schema:Person
148 sg:person.0612442642.09 schema:affiliation https://www.grid.ac/institutes/grid.416383.b
149 schema:familyName Zaveri
150 schema:givenName Shabber
151 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0612442642.09
152 rdf:type schema:Person
153 sg:person.0750376105.88 schema:affiliation https://www.grid.ac/institutes/grid.416467.6
154 schema:familyName Mehta
155 schema:givenName Sanket
156 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0750376105.88
157 rdf:type schema:Person
158 sg:pub.10.1186/1471-2407-14-183 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019880515
159 https://doi.org/10.1186/1471-2407-14-183
160 rdf:type schema:CreativeWork
161 sg:pub.10.1245/s10434-008-9966-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030091417
162 https://doi.org/10.1245/s10434-008-9966-2
163 rdf:type schema:CreativeWork
164 sg:pub.10.1245/s10434-010-1039-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050112795
165 https://doi.org/10.1245/s10434-010-1039-7
166 rdf:type schema:CreativeWork
167 sg:pub.10.1245/s10434-011-1631-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012489432
168 https://doi.org/10.1245/s10434-011-1631-5
169 rdf:type schema:CreativeWork
170 sg:pub.10.1245/s10434-015-4387-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011189090
171 https://doi.org/10.1245/s10434-015-4387-5
172 rdf:type schema:CreativeWork
173 https://doi.org/10.1002/bjs.5863 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037471832
174 rdf:type schema:CreativeWork
175 https://doi.org/10.1002/cncr.25356 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008199995
176 rdf:type schema:CreativeWork
177 https://doi.org/10.1016/j.ejca.2013.09.024 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050471755
178 rdf:type schema:CreativeWork
179 https://doi.org/10.1016/j.ejso.2006.03.005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036950189
180 rdf:type schema:CreativeWork
181 https://doi.org/10.1016/j.ejso.2010.05.007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050171543
182 rdf:type schema:CreativeWork
183 https://doi.org/10.1016/j.ejso.2013.09.030 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016839273
184 rdf:type schema:CreativeWork
185 https://doi.org/10.1097/00000658-199501000-00004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007603247
186 rdf:type schema:CreativeWork
187 https://doi.org/10.1097/ppo.0b013e3181a58d56 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025819247
188 rdf:type schema:CreativeWork
189 https://doi.org/10.1097/sla.0b013e3181a45d86 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019299634
190 rdf:type schema:CreativeWork
191 https://doi.org/10.1097/sla.0b013e31827e9289 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052087597
192 rdf:type schema:CreativeWork
193 https://doi.org/10.1111/igc.0b013e3181c50cde schema:sameAs https://app.dimensions.ai/details/publication/pub.1061838188
194 rdf:type schema:CreativeWork
195 https://doi.org/10.1200/jco.2007.11.0833 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037561935
196 rdf:type schema:CreativeWork
197 https://doi.org/10.1200/jco.2009.23.9285 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011683692
198 rdf:type schema:CreativeWork
199 https://doi.org/10.1200/jco.2009.23.9640 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019587384
200 rdf:type schema:CreativeWork
201 https://doi.org/10.1200/jco.2011.39.7166 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053361244
202 rdf:type schema:CreativeWork
203 https://doi.org/10.2174/138161212802002616 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069168242
204 rdf:type schema:CreativeWork
205 https://doi.org/10.3747/co.22.2058 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004902730
206 rdf:type schema:CreativeWork
207 https://doi.org/10.3747/co.v18i2.663 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006346070
208 rdf:type schema:CreativeWork
209 https://www.grid.ac/institutes/grid.413839.4 schema:alternateName Apollo Hospitals
210 schema:name Department of Surgical Oncology, Apollo Hospital, Chennai, India
211 rdf:type schema:Organization
212 https://www.grid.ac/institutes/grid.415235.4 schema:alternateName MedStar Washington Hospital Center
213 schema:name Washington Cancer Institute, MedStar Washington Hospital Center, Washington, DC, USA
214 rdf:type schema:Organization
215 https://www.grid.ac/institutes/grid.416383.b schema:alternateName Manipal Hospital
216 schema:name Department of Surgical Oncology, Manipal Hospital, Bangalore, India
217 rdf:type schema:Organization
218 https://www.grid.ac/institutes/grid.416467.6 schema:alternateName Saifee Hospital
219 schema:name Department of Surgical Oncology, Saifee Hospital, Mumbai, India
220 rdf:type schema:Organization
221 https://www.grid.ac/institutes/grid.417968.5 schema:alternateName Fortis Hospital
222 schema:name Department of Surgical Oncology, Fortis Hospital, 154/9 Bannerghatta road, Opposite IIM-Bangalore, -560076, Bangalore, India
223 rdf:type schema:Organization
224 https://www.grid.ac/institutes/grid.418600.b schema:alternateName Cancer Institute
225 schema:name Department of Surgical Oncology, Cancer Institute (WIA), Chennai, India
226 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...