Cytoreductive Surgery plus HIPEC for Peritoneal Metastases from Colorectal Cancer View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2016-06

AUTHORS

Aditi Bhatt, Diane Goéré

ABSTRACT

Occurring either synchronously or metachronously to the primary tumor, peritoneal metastases (PM) are diagnosed in 8 to 20 % of the patients with colorectal cancer (CRC). Prognosis of these patients appears to be worse than those with other sites of metastases. While systemic therapy has shown significant prolongation of survival in patients with stage IV colorectal cancer, the outcomes in the subset of patients with PM has been much inferior. Over the last 2 decades, cytoreductive surgery (CRS) followed by hyperthermic intraperitoneal chemotherapy (HIPEC) have been effective in substantially prolonging survival in patients with colorectal PM and have the potential to cure certain patients as well. This article reviews the current evidence for CRS and HIPEC to treat colorectal PM as well as future research going on in this form of locoregional treatment. More... »

PAGES

177-187

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  • Identifiers

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    http://scigraph.springernature.com/pub.10.1007/s13193-016-0499-z

    DOI

    http://dx.doi.org/10.1007/s13193-016-0499-z

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1003094531

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/27065708


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