MicroRNA-mediated drug resistance in breast cancer View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2011-08

AUTHORS

Kristy R. Kutanzi, Olga V. Yurchenko, Frederick A. Beland, Vasyl’ F. Checkhun, Igor P. Pogribny

ABSTRACT

Chemoresistance is one of the major hurdles to overcome for the successful treatment of breast cancer. At present, there are several mechanisms proposed to explain drug resistance to chemotherapeutic agents, including decreased intracellular drug concentrations, mediated by drug transporters and metabolic enzymes; impaired cellular responses that affect cell cycle arrest, apoptosis, and DNA repair; the induction of signaling pathways that promote the progression of cancer cell populations; perturbations in DNA methylation and histone modifications; and alterations in the availability of drug targets. Both genetic and epigenetic theories have been put forward to explain the mechanisms of drug resistance. Recently, a small non-coding class of RNAs, known as microRNAs, has been identified as master regulators of key genes implicated in mechanisms of chemoresistance. This article reviews the role of microRNAs in regulating chemoresistance and highlights potential therapeutic targets for reversing miRNA-mediated drug resistance. In the future, microRNA-based treatments, in combination with traditional chemotherapy, may be a new strategy for the clinical management of drug-resistant breast cancers. More... »

PAGES

171-185

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s13148-011-0040-8

DOI

http://dx.doi.org/10.1007/s13148-011-0040-8

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1040990399

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/21949547


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Oncology and Carcinogenesis", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "National Center for Toxicological Research", 
          "id": "https://www.grid.ac/institutes/grid.483504.e", 
          "name": [
            "Division of Biochemical Toxicology, National Center for Toxicological Research, 3900 NCTR Rd., 72079, Jefferson, AR, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kutanzi", 
        "givenName": "Kristy R.", 
        "id": "sg:person.010406265747.38", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010406265747.38"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "R.E.Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology", 
          "id": "https://www.grid.ac/institutes/grid.430311.4", 
          "name": [
            "Department of Mechanisms of Anticancer Therapy, R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, Kyiv, Ukraine"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Yurchenko", 
        "givenName": "Olga V.", 
        "id": "sg:person.01025737423.27", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01025737423.27"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "National Center for Toxicological Research", 
          "id": "https://www.grid.ac/institutes/grid.483504.e", 
          "name": [
            "Division of Biochemical Toxicology, National Center for Toxicological Research, 3900 NCTR Rd., 72079, Jefferson, AR, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Beland", 
        "givenName": "Frederick A.", 
        "id": "sg:person.0737742517.20", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0737742517.20"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "R.E.Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology", 
          "id": "https://www.grid.ac/institutes/grid.430311.4", 
          "name": [
            "Department of Mechanisms of Anticancer Therapy, R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, Kyiv, Ukraine"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Checkhun", 
        "givenName": "Vasyl\u2019 F.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "National Center for Toxicological Research", 
          "id": "https://www.grid.ac/institutes/grid.483504.e", 
          "name": [
            "Division of Biochemical Toxicology, National Center for Toxicological Research, 3900 NCTR Rd., 72079, Jefferson, AR, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pogribny", 
        "givenName": "Igor P.", 
        "id": "sg:person.01054171117.27", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01054171117.27"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1158/1535-7163.mct-08-0021", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000376245"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1101/gad.1767609", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000499471"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m111.227611", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000527084"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/0008-5472.can-08-2920", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000717609"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1471-2407-11-49", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000827134", 
          "https://doi.org/10.1186/1471-2407-11-49"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sla.0b013e3181cc939f", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001723650"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sla.0b013e3181cc939f", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001723650"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sla.0b013e3181cc939f", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001723650"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.0803055105", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002544487"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.0707351104", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003925185"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m806041200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004856248"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1534/genetics.105.049791", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004941016"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1534/genetics.105.049791", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004941016"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ijc.24972", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004974359"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ijc.24972", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004974359"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-1-4615-1173-1_13", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005017729", 
          "https://doi.org/10.1007/978-1-4615-1173-1_13"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-1-4615-1173-1_13", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005017729", 
          "https://doi.org/10.1007/978-1-4615-1173-1_13"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/onc.2010.487", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005556033", 
          "https://doi.org/10.1038/onc.2010.487"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1124/dmd.109.027680", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007637787"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.1015541107", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007992906"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/153303461000900109", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008289885"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/153303461000900109", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008289885"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/gb-2007-8-10-r214", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008503544", 
          "https://doi.org/10.1186/gb-2007-8-10-r214"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3322/caac.20107", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009055747"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/hep.23915", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009079289"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/hep.23915", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009079289"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature09267", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009165330", 
          "https://doi.org/10.1038/nature09267"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature09267", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009165330", 
          "https://doi.org/10.1038/nature09267"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/1535-7163.mct-06-0663", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009271464"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrm2632", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009902558", 
          "https://doi.org/10.1038/nrm2632"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cell.2009.06.034", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010114196"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m804612200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010531395"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10549-005-9070-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011886505", 
          "https://doi.org/10.1007/s10549-005-9070-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10549-005-9070-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011886505", 
          "https://doi.org/10.1007/s10549-005-9070-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.gene.2009.04.027", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012082264"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1098/rstb.2005.1685", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012346184"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1098/rstb.2005.1685", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012346184"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.molmed.2011.01.006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012654182"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/nar/gkn522", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012733286"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/bcr2789", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013292301", 
          "https://doi.org/10.1186/bcr2789"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/blood-2009-09-243147", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013451101"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bcp.2009.10.017", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014406384"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/1078-0432.ccr-09-1070", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014781757"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0010859", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014897599"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00109-010-0716-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014934163", 
          "https://doi.org/10.1007/s00109-010-0716-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ijc.25191", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014976469"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ijc.25191", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014976469"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0006229", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015256786"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1149460", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015783172"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10620-009-1051-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015905130", 
          "https://doi.org/10.1007/s10620-009-1051-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10620-009-1051-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015905130", 
          "https://doi.org/10.1007/s10620-009-1051-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m210256200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017827262"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1471-2407-10-47", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018433372", 
          "https://doi.org/10.1186/1471-2407-10-47"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4049/jimmunol.0904060", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018746068"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nsmb1167", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018871939", 
          "https://doi.org/10.1038/nsmb1167"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nsmb1167", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018871939", 
          "https://doi.org/10.1038/nsmb1167"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10495-008-0256-z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019696063", 
          "https://doi.org/10.1007/s10495-008-0256-z"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10495-008-0256-z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019696063", 
          "https://doi.org/10.1007/s10495-008-0256-z"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature02625", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019871284", 
          "https://doi.org/10.1038/nature02625"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature02625", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019871284", 
          "https://doi.org/10.1038/nature02625"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/carcin/bgp304", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020168607"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10549-011-1424-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020569096", 
          "https://doi.org/10.1007/s10549-011-1424-3"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ncb2024", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020751102", 
          "https://doi.org/10.1038/ncb2024"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ncb2024", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020751102", 
          "https://doi.org/10.1038/ncb2024"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/0008-5472.can-09-2777", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021371064"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bbrc.2010.05.082", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021396288"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jcp.20515", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021520576"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jcp.20515", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021520576"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature07228", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021877727", 
          "https://doi.org/10.1038/nature07228"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0001908", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021959241"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1471-2407-8-266", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022974974", 
          "https://doi.org/10.1186/1471-2407-8-266"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/0008-5472.can-08-0180", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023269013"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.onc.1209462", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023344250", 
          "https://doi.org/10.1038/sj.onc.1209462"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.onc.1209462", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023344250", 
          "https://doi.org/10.1038/sj.onc.1209462"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.onc.1209737", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023540099", 
          "https://doi.org/10.1038/sj.onc.1209737"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.onc.1209737", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023540099", 
          "https://doi.org/10.1038/sj.onc.1209737"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.onc.1209737", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023540099", 
          "https://doi.org/10.1038/sj.onc.1209737"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cell.2011.02.013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023540354"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.dnarep.2010.08.007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023729463"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.0506654102", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023841510"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1083/jcb.200801079", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024106955"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature03702", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024825726", 
          "https://doi.org/10.1038/nature03702"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature03702", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024825726", 
          "https://doi.org/10.1038/nature03702"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.canlet.2009.04.031", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024839326"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ijc.25260", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024917019"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ijc.25260", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024917019"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s12032-011-9823-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025397903", 
          "https://doi.org/10.1007/s12032-011-9823-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/1078-0432.ccr-06-1109", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025893789"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10549-009-0716-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026305655", 
          "https://doi.org/10.1007/s10549-009-0716-3"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10549-009-0716-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026305655", 
          "https://doi.org/10.1007/s10549-009-0716-3"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1471-2407-10-27", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026316878", 
          "https://doi.org/10.1186/1471-2407-10-27"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.onc.1210742", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026808469", 
          "https://doi.org/10.1038/sj.onc.1210742"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/0008-5472.can-05-1783", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027381088"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0005436", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028386927"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ccr.2009.10.014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029310321"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/0008-5472.can-06-3307", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029555834"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m005824200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029920271"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bsr20080032", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030179692"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/bcr1614", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030320001", 
          "https://doi.org/10.1186/bcr1614"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0378-1119(99)00571-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030852561"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0092-8674(04)00045-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031254572"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ijc.25126", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031550701"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ijc.25126", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031550701"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s12032-009-9225-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031632567", 
          "https://doi.org/10.1007/s12032-009-9225-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s12032-009-9225-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031632567", 
          "https://doi.org/10.1007/s12032-009-9225-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/nar/gkp657", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031892381"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1476-4598-5-29", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031942139", 
          "https://doi.org/10.1186/1476-4598-5-29"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1038/embor.2008.74", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032429234"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.molcel.2011.01.005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032994011"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/jnci/djq102", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033238875"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.0905718106", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033277221"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/1535-7163.mct-08-1046", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033400586"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1242/jcs.056812", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033645338"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/0008-5472.can-07-1484", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033873414"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1146/annurev-pharmtox-010510-100517", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034090735"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1023/b:clin.0000037697.76011.1d", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034162687", 
          "https://doi.org/10.1023/b:clin.0000037697.76011.1d"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/0008-5472.can-10-3604", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034584563"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1038/sj.emboj.7600385", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035197644"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.onc.1206933", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035533524", 
          "https://doi.org/10.1038/sj.onc.1206933"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.onc.1206933", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035533524", 
          "https://doi.org/10.1038/sj.onc.1206933"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1096/fj.08-125856", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036191540"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.bjc.6603024", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036503911", 
          "https://doi.org/10.1038/sj.bjc.6603024"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.bjc.6603024", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036503911", 
          "https://doi.org/10.1038/sj.bjc.6603024"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0016138", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037075915"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/bcr2766", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037607196", 
          "https://doi.org/10.1186/bcr2766"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nm0311-288", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037978149", 
          "https://doi.org/10.1038/nm0311-288"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m109.027466", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038031135"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/1078-0432.ccr-04-2421", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038294800"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/onc.2009.459", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039107474", 
          "https://doi.org/10.1038/onc.2009.459"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/onc.2010.463", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039577937", 
          "https://doi.org/10.1038/onc.2010.463"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0014-4827(03)00342-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040257036"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0014-4827(03)00342-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040257036"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.onc.1208955", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041309729", 
          "https://doi.org/10.1038/sj.onc.1208955"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.onc.1208955", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041309729", 
          "https://doi.org/10.1038/sj.onc.1208955"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/bioinformatics/btn646", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041538981"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/1535-7163.mct-07-0009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041578841"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.c800074200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041926183"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ygyno.2008.08.017", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042335041"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.febslet.2008.03.057", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042697505"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1054/drup.1999.0108", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042919591"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature06100", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043590665", 
          "https://doi.org/10.1038/nature06100"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s12033-010-9321-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044187462", 
          "https://doi.org/10.1007/s12033-010-9321-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s12033-010-9321-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044187462", 
          "https://doi.org/10.1007/s12033-010-9321-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/mcb.00941-08", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045279634"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/0008-5472.can-08-2765", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045402097"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.canlet.2005.01.038", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045801267"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.0707628104", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047085275"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/1541-7786.mcr-10-0362", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047153997"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2147/btt.s3479", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047527339"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1261/rna.972008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047682260"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nsmb.1533", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048238761", 
          "https://doi.org/10.1038/nsmb.1533"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4049/jimmunol.1001633", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048573458"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00018-009-0015-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049079883", 
          "https://doi.org/10.1007/s00018-009-0015-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00018-009-0015-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049079883", 
          "https://doi.org/10.1007/s00018-009-0015-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00018-009-0015-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049079883", 
          "https://doi.org/10.1007/s00018-009-0015-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/cr.2008.45", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049986223", 
          "https://doi.org/10.1038/cr.2008.45"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ccr.2006.04.020", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050886249"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.leukres.2009.10.002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050910149"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0013735", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051824513"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.febslet.2005.12.060", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052553989"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.drup.2010.07.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052859047"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0005-2736(99)00169-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053513377"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m109.083337", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053532035"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2174/156800906777723958", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1069190753"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2174/156802606776173483", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1069193301"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074512828", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074630046", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1075255995", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077056189", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082889936", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082903134", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1096/fasebj.11.12.9337147", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083161435"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2011-08", 
    "datePublishedReg": "2011-08-01", 
    "description": "Chemoresistance is one of the major hurdles to overcome for the successful treatment of breast cancer. At present, there are several mechanisms proposed to explain drug resistance to chemotherapeutic agents, including decreased intracellular drug concentrations, mediated by drug transporters and metabolic enzymes; impaired cellular responses that affect cell cycle arrest, apoptosis, and DNA repair; the induction of signaling pathways that promote the progression of cancer cell populations; perturbations in DNA methylation and histone modifications; and alterations in the availability of drug targets. Both genetic and epigenetic theories have been put forward to explain the mechanisms of drug resistance. Recently, a small non-coding class of RNAs, known as microRNAs, has been identified as master regulators of key genes implicated in mechanisms of chemoresistance. This article reviews the role of microRNAs in regulating chemoresistance and highlights potential therapeutic targets for reversing miRNA-mediated drug resistance. In the future, microRNA-based treatments, in combination with traditional chemotherapy, may be a new strategy for the clinical management of drug-resistant breast cancers.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s13148-011-0040-8", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1042271", 
        "issn": [
          "1868-7075", 
          "1868-7083"
        ], 
        "name": "Clinical Epigenetics", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "2", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "2"
      }
    ], 
    "name": "MicroRNA-mediated drug resistance in breast cancer", 
    "pagination": "171-185", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "c343e25e4973000439f678b2ebec98495d2630c6a8b1f8da89b6853fa29cb574"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "21949547"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101516977"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s13148-011-0040-8"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1040990399"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s13148-011-0040-8", 
      "https://app.dimensions.ai/details/publication/pub.1040990399"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T02:11", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8700_00000523.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007%2Fs13148-011-0040-8"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s13148-011-0040-8'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s13148-011-0040-8'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s13148-011-0040-8'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s13148-011-0040-8'


 

This table displays all metadata directly associated to this object as RDF triples.

554 TRIPLES      21 PREDICATES      169 URIs      21 LITERALS      9 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s13148-011-0040-8 schema:about anzsrc-for:11
2 anzsrc-for:1112
3 schema:author N69b5b616349f4fe28a5d60cd70a14c86
4 schema:citation sg:pub.10.1007/978-1-4615-1173-1_13
5 sg:pub.10.1007/s00018-009-0015-5
6 sg:pub.10.1007/s00109-010-0716-0
7 sg:pub.10.1007/s10495-008-0256-z
8 sg:pub.10.1007/s10549-005-9070-2
9 sg:pub.10.1007/s10549-009-0716-3
10 sg:pub.10.1007/s10549-011-1424-3
11 sg:pub.10.1007/s10620-009-1051-6
12 sg:pub.10.1007/s12032-009-9225-9
13 sg:pub.10.1007/s12032-011-9823-1
14 sg:pub.10.1007/s12033-010-9321-2
15 sg:pub.10.1023/b:clin.0000037697.76011.1d
16 sg:pub.10.1038/cr.2008.45
17 sg:pub.10.1038/nature02625
18 sg:pub.10.1038/nature03702
19 sg:pub.10.1038/nature06100
20 sg:pub.10.1038/nature07228
21 sg:pub.10.1038/nature09267
22 sg:pub.10.1038/ncb2024
23 sg:pub.10.1038/nm0311-288
24 sg:pub.10.1038/nrm2632
25 sg:pub.10.1038/nsmb.1533
26 sg:pub.10.1038/nsmb1167
27 sg:pub.10.1038/onc.2009.459
28 sg:pub.10.1038/onc.2010.463
29 sg:pub.10.1038/onc.2010.487
30 sg:pub.10.1038/sj.bjc.6603024
31 sg:pub.10.1038/sj.onc.1206933
32 sg:pub.10.1038/sj.onc.1208955
33 sg:pub.10.1038/sj.onc.1209462
34 sg:pub.10.1038/sj.onc.1209737
35 sg:pub.10.1038/sj.onc.1210742
36 sg:pub.10.1186/1471-2407-10-27
37 sg:pub.10.1186/1471-2407-10-47
38 sg:pub.10.1186/1471-2407-11-49
39 sg:pub.10.1186/1471-2407-8-266
40 sg:pub.10.1186/1476-4598-5-29
41 sg:pub.10.1186/bcr1614
42 sg:pub.10.1186/bcr2766
43 sg:pub.10.1186/bcr2789
44 sg:pub.10.1186/gb-2007-8-10-r214
45 https://app.dimensions.ai/details/publication/pub.1074512828
46 https://app.dimensions.ai/details/publication/pub.1074630046
47 https://app.dimensions.ai/details/publication/pub.1075255995
48 https://app.dimensions.ai/details/publication/pub.1077056189
49 https://app.dimensions.ai/details/publication/pub.1082889936
50 https://app.dimensions.ai/details/publication/pub.1082903134
51 https://doi.org/10.1002/hep.23915
52 https://doi.org/10.1002/ijc.24972
53 https://doi.org/10.1002/ijc.25126
54 https://doi.org/10.1002/ijc.25191
55 https://doi.org/10.1002/ijc.25260
56 https://doi.org/10.1002/jcp.20515
57 https://doi.org/10.1016/j.bbrc.2010.05.082
58 https://doi.org/10.1016/j.bcp.2009.10.017
59 https://doi.org/10.1016/j.canlet.2005.01.038
60 https://doi.org/10.1016/j.canlet.2009.04.031
61 https://doi.org/10.1016/j.ccr.2006.04.020
62 https://doi.org/10.1016/j.ccr.2009.10.014
63 https://doi.org/10.1016/j.cell.2009.06.034
64 https://doi.org/10.1016/j.cell.2011.02.013
65 https://doi.org/10.1016/j.dnarep.2010.08.007
66 https://doi.org/10.1016/j.drup.2010.07.001
67 https://doi.org/10.1016/j.febslet.2005.12.060
68 https://doi.org/10.1016/j.febslet.2008.03.057
69 https://doi.org/10.1016/j.gene.2009.04.027
70 https://doi.org/10.1016/j.leukres.2009.10.002
71 https://doi.org/10.1016/j.molcel.2011.01.005
72 https://doi.org/10.1016/j.molmed.2011.01.006
73 https://doi.org/10.1016/j.ygyno.2008.08.017
74 https://doi.org/10.1016/s0005-2736(99)00169-8
75 https://doi.org/10.1016/s0014-4827(03)00342-2
76 https://doi.org/10.1016/s0092-8674(04)00045-5
77 https://doi.org/10.1016/s0378-1119(99)00571-5
78 https://doi.org/10.1038/embor.2008.74
79 https://doi.org/10.1038/sj.emboj.7600385
80 https://doi.org/10.1042/bsr20080032
81 https://doi.org/10.1054/drup.1999.0108
82 https://doi.org/10.1073/pnas.0506654102
83 https://doi.org/10.1073/pnas.0707351104
84 https://doi.org/10.1073/pnas.0707628104
85 https://doi.org/10.1073/pnas.0803055105
86 https://doi.org/10.1073/pnas.0905718106
87 https://doi.org/10.1073/pnas.1015541107
88 https://doi.org/10.1074/jbc.c800074200
89 https://doi.org/10.1074/jbc.m005824200
90 https://doi.org/10.1074/jbc.m109.027466
91 https://doi.org/10.1074/jbc.m109.083337
92 https://doi.org/10.1074/jbc.m111.227611
93 https://doi.org/10.1074/jbc.m210256200
94 https://doi.org/10.1074/jbc.m804612200
95 https://doi.org/10.1074/jbc.m806041200
96 https://doi.org/10.1083/jcb.200801079
97 https://doi.org/10.1093/bioinformatics/btn646
98 https://doi.org/10.1093/carcin/bgp304
99 https://doi.org/10.1093/jnci/djq102
100 https://doi.org/10.1093/nar/gkn522
101 https://doi.org/10.1093/nar/gkp657
102 https://doi.org/10.1096/fasebj.11.12.9337147
103 https://doi.org/10.1096/fj.08-125856
104 https://doi.org/10.1097/sla.0b013e3181cc939f
105 https://doi.org/10.1098/rstb.2005.1685
106 https://doi.org/10.1101/gad.1767609
107 https://doi.org/10.1124/dmd.109.027680
108 https://doi.org/10.1126/science.1149460
109 https://doi.org/10.1128/mcb.00941-08
110 https://doi.org/10.1146/annurev-pharmtox-010510-100517
111 https://doi.org/10.1158/0008-5472.can-05-1783
112 https://doi.org/10.1158/0008-5472.can-06-3307
113 https://doi.org/10.1158/0008-5472.can-07-1484
114 https://doi.org/10.1158/0008-5472.can-08-0180
115 https://doi.org/10.1158/0008-5472.can-08-2765
116 https://doi.org/10.1158/0008-5472.can-08-2920
117 https://doi.org/10.1158/0008-5472.can-09-2777
118 https://doi.org/10.1158/0008-5472.can-10-3604
119 https://doi.org/10.1158/1078-0432.ccr-04-2421
120 https://doi.org/10.1158/1078-0432.ccr-06-1109
121 https://doi.org/10.1158/1078-0432.ccr-09-1070
122 https://doi.org/10.1158/1535-7163.mct-06-0663
123 https://doi.org/10.1158/1535-7163.mct-07-0009
124 https://doi.org/10.1158/1535-7163.mct-08-0021
125 https://doi.org/10.1158/1535-7163.mct-08-1046
126 https://doi.org/10.1158/1541-7786.mcr-10-0362
127 https://doi.org/10.1177/153303461000900109
128 https://doi.org/10.1182/blood-2009-09-243147
129 https://doi.org/10.1242/jcs.056812
130 https://doi.org/10.1261/rna.972008
131 https://doi.org/10.1371/journal.pone.0001908
132 https://doi.org/10.1371/journal.pone.0005436
133 https://doi.org/10.1371/journal.pone.0006229
134 https://doi.org/10.1371/journal.pone.0010859
135 https://doi.org/10.1371/journal.pone.0013735
136 https://doi.org/10.1371/journal.pone.0016138
137 https://doi.org/10.1534/genetics.105.049791
138 https://doi.org/10.2147/btt.s3479
139 https://doi.org/10.2174/156800906777723958
140 https://doi.org/10.2174/156802606776173483
141 https://doi.org/10.3322/caac.20107
142 https://doi.org/10.4049/jimmunol.0904060
143 https://doi.org/10.4049/jimmunol.1001633
144 schema:datePublished 2011-08
145 schema:datePublishedReg 2011-08-01
146 schema:description Chemoresistance is one of the major hurdles to overcome for the successful treatment of breast cancer. At present, there are several mechanisms proposed to explain drug resistance to chemotherapeutic agents, including decreased intracellular drug concentrations, mediated by drug transporters and metabolic enzymes; impaired cellular responses that affect cell cycle arrest, apoptosis, and DNA repair; the induction of signaling pathways that promote the progression of cancer cell populations; perturbations in DNA methylation and histone modifications; and alterations in the availability of drug targets. Both genetic and epigenetic theories have been put forward to explain the mechanisms of drug resistance. Recently, a small non-coding class of RNAs, known as microRNAs, has been identified as master regulators of key genes implicated in mechanisms of chemoresistance. This article reviews the role of microRNAs in regulating chemoresistance and highlights potential therapeutic targets for reversing miRNA-mediated drug resistance. In the future, microRNA-based treatments, in combination with traditional chemotherapy, may be a new strategy for the clinical management of drug-resistant breast cancers.
147 schema:genre research_article
148 schema:inLanguage en
149 schema:isAccessibleForFree true
150 schema:isPartOf N03623c2463b749628b426cfc54f45c6b
151 Nc789eecc328f4c20855354533ee32fdc
152 sg:journal.1042271
153 schema:name MicroRNA-mediated drug resistance in breast cancer
154 schema:pagination 171-185
155 schema:productId N1bb08326a0ad43969475f7e352eaea5a
156 N3f22c18ee5694bad802e1c220880b0e3
157 N4cce2b2f3d20477eaee3e44bd9f4893e
158 N78872da880f7444b93d5db7afe84f6f6
159 N8f0ea612fa514232a38c1477b63f5ea0
160 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040990399
161 https://doi.org/10.1007/s13148-011-0040-8
162 schema:sdDatePublished 2019-04-11T02:11
163 schema:sdLicense https://scigraph.springernature.com/explorer/license/
164 schema:sdPublisher N3809ec6c0cb84984a746bfeb33162214
165 schema:url http://link.springer.com/10.1007%2Fs13148-011-0040-8
166 sgo:license sg:explorer/license/
167 sgo:sdDataset articles
168 rdf:type schema:ScholarlyArticle
169 N03623c2463b749628b426cfc54f45c6b schema:issueNumber 2
170 rdf:type schema:PublicationIssue
171 N0eef409d39774744ad5120e34c31dfd5 rdf:first Nb5d990e54e8a4178a3c4cf66c7e4e6fe
172 rdf:rest N7653bdfb812941409fcb32fef2da7c68
173 N1bb08326a0ad43969475f7e352eaea5a schema:name doi
174 schema:value 10.1007/s13148-011-0040-8
175 rdf:type schema:PropertyValue
176 N3809ec6c0cb84984a746bfeb33162214 schema:name Springer Nature - SN SciGraph project
177 rdf:type schema:Organization
178 N3f22c18ee5694bad802e1c220880b0e3 schema:name nlm_unique_id
179 schema:value 101516977
180 rdf:type schema:PropertyValue
181 N4cce2b2f3d20477eaee3e44bd9f4893e schema:name dimensions_id
182 schema:value pub.1040990399
183 rdf:type schema:PropertyValue
184 N69b5b616349f4fe28a5d60cd70a14c86 rdf:first sg:person.010406265747.38
185 rdf:rest Nb4e5757f4b8141a2be3a512a3983a7ed
186 N7653bdfb812941409fcb32fef2da7c68 rdf:first sg:person.01054171117.27
187 rdf:rest rdf:nil
188 N78872da880f7444b93d5db7afe84f6f6 schema:name readcube_id
189 schema:value c343e25e4973000439f678b2ebec98495d2630c6a8b1f8da89b6853fa29cb574
190 rdf:type schema:PropertyValue
191 N8f0ea612fa514232a38c1477b63f5ea0 schema:name pubmed_id
192 schema:value 21949547
193 rdf:type schema:PropertyValue
194 N987f9dd94e49433c957ed0282a2692a6 rdf:first sg:person.0737742517.20
195 rdf:rest N0eef409d39774744ad5120e34c31dfd5
196 Nb4e5757f4b8141a2be3a512a3983a7ed rdf:first sg:person.01025737423.27
197 rdf:rest N987f9dd94e49433c957ed0282a2692a6
198 Nb5d990e54e8a4178a3c4cf66c7e4e6fe schema:affiliation https://www.grid.ac/institutes/grid.430311.4
199 schema:familyName Checkhun
200 schema:givenName Vasyl’ F.
201 rdf:type schema:Person
202 Nc789eecc328f4c20855354533ee32fdc schema:volumeNumber 2
203 rdf:type schema:PublicationVolume
204 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
205 schema:name Medical and Health Sciences
206 rdf:type schema:DefinedTerm
207 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
208 schema:name Oncology and Carcinogenesis
209 rdf:type schema:DefinedTerm
210 sg:journal.1042271 schema:issn 1868-7075
211 1868-7083
212 schema:name Clinical Epigenetics
213 rdf:type schema:Periodical
214 sg:person.01025737423.27 schema:affiliation https://www.grid.ac/institutes/grid.430311.4
215 schema:familyName Yurchenko
216 schema:givenName Olga V.
217 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01025737423.27
218 rdf:type schema:Person
219 sg:person.010406265747.38 schema:affiliation https://www.grid.ac/institutes/grid.483504.e
220 schema:familyName Kutanzi
221 schema:givenName Kristy R.
222 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010406265747.38
223 rdf:type schema:Person
224 sg:person.01054171117.27 schema:affiliation https://www.grid.ac/institutes/grid.483504.e
225 schema:familyName Pogribny
226 schema:givenName Igor P.
227 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01054171117.27
228 rdf:type schema:Person
229 sg:person.0737742517.20 schema:affiliation https://www.grid.ac/institutes/grid.483504.e
230 schema:familyName Beland
231 schema:givenName Frederick A.
232 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0737742517.20
233 rdf:type schema:Person
234 sg:pub.10.1007/978-1-4615-1173-1_13 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005017729
235 https://doi.org/10.1007/978-1-4615-1173-1_13
236 rdf:type schema:CreativeWork
237 sg:pub.10.1007/s00018-009-0015-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049079883
238 https://doi.org/10.1007/s00018-009-0015-5
239 rdf:type schema:CreativeWork
240 sg:pub.10.1007/s00109-010-0716-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014934163
241 https://doi.org/10.1007/s00109-010-0716-0
242 rdf:type schema:CreativeWork
243 sg:pub.10.1007/s10495-008-0256-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1019696063
244 https://doi.org/10.1007/s10495-008-0256-z
245 rdf:type schema:CreativeWork
246 sg:pub.10.1007/s10549-005-9070-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011886505
247 https://doi.org/10.1007/s10549-005-9070-2
248 rdf:type schema:CreativeWork
249 sg:pub.10.1007/s10549-009-0716-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026305655
250 https://doi.org/10.1007/s10549-009-0716-3
251 rdf:type schema:CreativeWork
252 sg:pub.10.1007/s10549-011-1424-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020569096
253 https://doi.org/10.1007/s10549-011-1424-3
254 rdf:type schema:CreativeWork
255 sg:pub.10.1007/s10620-009-1051-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015905130
256 https://doi.org/10.1007/s10620-009-1051-6
257 rdf:type schema:CreativeWork
258 sg:pub.10.1007/s12032-009-9225-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031632567
259 https://doi.org/10.1007/s12032-009-9225-9
260 rdf:type schema:CreativeWork
261 sg:pub.10.1007/s12032-011-9823-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025397903
262 https://doi.org/10.1007/s12032-011-9823-1
263 rdf:type schema:CreativeWork
264 sg:pub.10.1007/s12033-010-9321-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044187462
265 https://doi.org/10.1007/s12033-010-9321-2
266 rdf:type schema:CreativeWork
267 sg:pub.10.1023/b:clin.0000037697.76011.1d schema:sameAs https://app.dimensions.ai/details/publication/pub.1034162687
268 https://doi.org/10.1023/b:clin.0000037697.76011.1d
269 rdf:type schema:CreativeWork
270 sg:pub.10.1038/cr.2008.45 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049986223
271 https://doi.org/10.1038/cr.2008.45
272 rdf:type schema:CreativeWork
273 sg:pub.10.1038/nature02625 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019871284
274 https://doi.org/10.1038/nature02625
275 rdf:type schema:CreativeWork
276 sg:pub.10.1038/nature03702 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024825726
277 https://doi.org/10.1038/nature03702
278 rdf:type schema:CreativeWork
279 sg:pub.10.1038/nature06100 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043590665
280 https://doi.org/10.1038/nature06100
281 rdf:type schema:CreativeWork
282 sg:pub.10.1038/nature07228 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021877727
283 https://doi.org/10.1038/nature07228
284 rdf:type schema:CreativeWork
285 sg:pub.10.1038/nature09267 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009165330
286 https://doi.org/10.1038/nature09267
287 rdf:type schema:CreativeWork
288 sg:pub.10.1038/ncb2024 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020751102
289 https://doi.org/10.1038/ncb2024
290 rdf:type schema:CreativeWork
291 sg:pub.10.1038/nm0311-288 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037978149
292 https://doi.org/10.1038/nm0311-288
293 rdf:type schema:CreativeWork
294 sg:pub.10.1038/nrm2632 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009902558
295 https://doi.org/10.1038/nrm2632
296 rdf:type schema:CreativeWork
297 sg:pub.10.1038/nsmb.1533 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048238761
298 https://doi.org/10.1038/nsmb.1533
299 rdf:type schema:CreativeWork
300 sg:pub.10.1038/nsmb1167 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018871939
301 https://doi.org/10.1038/nsmb1167
302 rdf:type schema:CreativeWork
303 sg:pub.10.1038/onc.2009.459 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039107474
304 https://doi.org/10.1038/onc.2009.459
305 rdf:type schema:CreativeWork
306 sg:pub.10.1038/onc.2010.463 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039577937
307 https://doi.org/10.1038/onc.2010.463
308 rdf:type schema:CreativeWork
309 sg:pub.10.1038/onc.2010.487 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005556033
310 https://doi.org/10.1038/onc.2010.487
311 rdf:type schema:CreativeWork
312 sg:pub.10.1038/sj.bjc.6603024 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036503911
313 https://doi.org/10.1038/sj.bjc.6603024
314 rdf:type schema:CreativeWork
315 sg:pub.10.1038/sj.onc.1206933 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035533524
316 https://doi.org/10.1038/sj.onc.1206933
317 rdf:type schema:CreativeWork
318 sg:pub.10.1038/sj.onc.1208955 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041309729
319 https://doi.org/10.1038/sj.onc.1208955
320 rdf:type schema:CreativeWork
321 sg:pub.10.1038/sj.onc.1209462 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023344250
322 https://doi.org/10.1038/sj.onc.1209462
323 rdf:type schema:CreativeWork
324 sg:pub.10.1038/sj.onc.1209737 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023540099
325 https://doi.org/10.1038/sj.onc.1209737
326 rdf:type schema:CreativeWork
327 sg:pub.10.1038/sj.onc.1210742 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026808469
328 https://doi.org/10.1038/sj.onc.1210742
329 rdf:type schema:CreativeWork
330 sg:pub.10.1186/1471-2407-10-27 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026316878
331 https://doi.org/10.1186/1471-2407-10-27
332 rdf:type schema:CreativeWork
333 sg:pub.10.1186/1471-2407-10-47 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018433372
334 https://doi.org/10.1186/1471-2407-10-47
335 rdf:type schema:CreativeWork
336 sg:pub.10.1186/1471-2407-11-49 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000827134
337 https://doi.org/10.1186/1471-2407-11-49
338 rdf:type schema:CreativeWork
339 sg:pub.10.1186/1471-2407-8-266 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022974974
340 https://doi.org/10.1186/1471-2407-8-266
341 rdf:type schema:CreativeWork
342 sg:pub.10.1186/1476-4598-5-29 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031942139
343 https://doi.org/10.1186/1476-4598-5-29
344 rdf:type schema:CreativeWork
345 sg:pub.10.1186/bcr1614 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030320001
346 https://doi.org/10.1186/bcr1614
347 rdf:type schema:CreativeWork
348 sg:pub.10.1186/bcr2766 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037607196
349 https://doi.org/10.1186/bcr2766
350 rdf:type schema:CreativeWork
351 sg:pub.10.1186/bcr2789 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013292301
352 https://doi.org/10.1186/bcr2789
353 rdf:type schema:CreativeWork
354 sg:pub.10.1186/gb-2007-8-10-r214 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008503544
355 https://doi.org/10.1186/gb-2007-8-10-r214
356 rdf:type schema:CreativeWork
357 https://app.dimensions.ai/details/publication/pub.1074512828 schema:CreativeWork
358 https://app.dimensions.ai/details/publication/pub.1074630046 schema:CreativeWork
359 https://app.dimensions.ai/details/publication/pub.1075255995 schema:CreativeWork
360 https://app.dimensions.ai/details/publication/pub.1077056189 schema:CreativeWork
361 https://app.dimensions.ai/details/publication/pub.1082889936 schema:CreativeWork
362 https://app.dimensions.ai/details/publication/pub.1082903134 schema:CreativeWork
363 https://doi.org/10.1002/hep.23915 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009079289
364 rdf:type schema:CreativeWork
365 https://doi.org/10.1002/ijc.24972 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004974359
366 rdf:type schema:CreativeWork
367 https://doi.org/10.1002/ijc.25126 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031550701
368 rdf:type schema:CreativeWork
369 https://doi.org/10.1002/ijc.25191 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014976469
370 rdf:type schema:CreativeWork
371 https://doi.org/10.1002/ijc.25260 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024917019
372 rdf:type schema:CreativeWork
373 https://doi.org/10.1002/jcp.20515 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021520576
374 rdf:type schema:CreativeWork
375 https://doi.org/10.1016/j.bbrc.2010.05.082 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021396288
376 rdf:type schema:CreativeWork
377 https://doi.org/10.1016/j.bcp.2009.10.017 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014406384
378 rdf:type schema:CreativeWork
379 https://doi.org/10.1016/j.canlet.2005.01.038 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045801267
380 rdf:type schema:CreativeWork
381 https://doi.org/10.1016/j.canlet.2009.04.031 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024839326
382 rdf:type schema:CreativeWork
383 https://doi.org/10.1016/j.ccr.2006.04.020 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050886249
384 rdf:type schema:CreativeWork
385 https://doi.org/10.1016/j.ccr.2009.10.014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029310321
386 rdf:type schema:CreativeWork
387 https://doi.org/10.1016/j.cell.2009.06.034 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010114196
388 rdf:type schema:CreativeWork
389 https://doi.org/10.1016/j.cell.2011.02.013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023540354
390 rdf:type schema:CreativeWork
391 https://doi.org/10.1016/j.dnarep.2010.08.007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023729463
392 rdf:type schema:CreativeWork
393 https://doi.org/10.1016/j.drup.2010.07.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052859047
394 rdf:type schema:CreativeWork
395 https://doi.org/10.1016/j.febslet.2005.12.060 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052553989
396 rdf:type schema:CreativeWork
397 https://doi.org/10.1016/j.febslet.2008.03.057 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042697505
398 rdf:type schema:CreativeWork
399 https://doi.org/10.1016/j.gene.2009.04.027 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012082264
400 rdf:type schema:CreativeWork
401 https://doi.org/10.1016/j.leukres.2009.10.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050910149
402 rdf:type schema:CreativeWork
403 https://doi.org/10.1016/j.molcel.2011.01.005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032994011
404 rdf:type schema:CreativeWork
405 https://doi.org/10.1016/j.molmed.2011.01.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012654182
406 rdf:type schema:CreativeWork
407 https://doi.org/10.1016/j.ygyno.2008.08.017 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042335041
408 rdf:type schema:CreativeWork
409 https://doi.org/10.1016/s0005-2736(99)00169-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053513377
410 rdf:type schema:CreativeWork
411 https://doi.org/10.1016/s0014-4827(03)00342-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040257036
412 rdf:type schema:CreativeWork
413 https://doi.org/10.1016/s0092-8674(04)00045-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031254572
414 rdf:type schema:CreativeWork
415 https://doi.org/10.1016/s0378-1119(99)00571-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030852561
416 rdf:type schema:CreativeWork
417 https://doi.org/10.1038/embor.2008.74 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032429234
418 rdf:type schema:CreativeWork
419 https://doi.org/10.1038/sj.emboj.7600385 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035197644
420 rdf:type schema:CreativeWork
421 https://doi.org/10.1042/bsr20080032 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030179692
422 rdf:type schema:CreativeWork
423 https://doi.org/10.1054/drup.1999.0108 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042919591
424 rdf:type schema:CreativeWork
425 https://doi.org/10.1073/pnas.0506654102 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023841510
426 rdf:type schema:CreativeWork
427 https://doi.org/10.1073/pnas.0707351104 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003925185
428 rdf:type schema:CreativeWork
429 https://doi.org/10.1073/pnas.0707628104 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047085275
430 rdf:type schema:CreativeWork
431 https://doi.org/10.1073/pnas.0803055105 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002544487
432 rdf:type schema:CreativeWork
433 https://doi.org/10.1073/pnas.0905718106 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033277221
434 rdf:type schema:CreativeWork
435 https://doi.org/10.1073/pnas.1015541107 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007992906
436 rdf:type schema:CreativeWork
437 https://doi.org/10.1074/jbc.c800074200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041926183
438 rdf:type schema:CreativeWork
439 https://doi.org/10.1074/jbc.m005824200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029920271
440 rdf:type schema:CreativeWork
441 https://doi.org/10.1074/jbc.m109.027466 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038031135
442 rdf:type schema:CreativeWork
443 https://doi.org/10.1074/jbc.m109.083337 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053532035
444 rdf:type schema:CreativeWork
445 https://doi.org/10.1074/jbc.m111.227611 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000527084
446 rdf:type schema:CreativeWork
447 https://doi.org/10.1074/jbc.m210256200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017827262
448 rdf:type schema:CreativeWork
449 https://doi.org/10.1074/jbc.m804612200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010531395
450 rdf:type schema:CreativeWork
451 https://doi.org/10.1074/jbc.m806041200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004856248
452 rdf:type schema:CreativeWork
453 https://doi.org/10.1083/jcb.200801079 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024106955
454 rdf:type schema:CreativeWork
455 https://doi.org/10.1093/bioinformatics/btn646 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041538981
456 rdf:type schema:CreativeWork
457 https://doi.org/10.1093/carcin/bgp304 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020168607
458 rdf:type schema:CreativeWork
459 https://doi.org/10.1093/jnci/djq102 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033238875
460 rdf:type schema:CreativeWork
461 https://doi.org/10.1093/nar/gkn522 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012733286
462 rdf:type schema:CreativeWork
463 https://doi.org/10.1093/nar/gkp657 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031892381
464 rdf:type schema:CreativeWork
465 https://doi.org/10.1096/fasebj.11.12.9337147 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083161435
466 rdf:type schema:CreativeWork
467 https://doi.org/10.1096/fj.08-125856 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036191540
468 rdf:type schema:CreativeWork
469 https://doi.org/10.1097/sla.0b013e3181cc939f schema:sameAs https://app.dimensions.ai/details/publication/pub.1001723650
470 rdf:type schema:CreativeWork
471 https://doi.org/10.1098/rstb.2005.1685 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012346184
472 rdf:type schema:CreativeWork
473 https://doi.org/10.1101/gad.1767609 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000499471
474 rdf:type schema:CreativeWork
475 https://doi.org/10.1124/dmd.109.027680 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007637787
476 rdf:type schema:CreativeWork
477 https://doi.org/10.1126/science.1149460 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015783172
478 rdf:type schema:CreativeWork
479 https://doi.org/10.1128/mcb.00941-08 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045279634
480 rdf:type schema:CreativeWork
481 https://doi.org/10.1146/annurev-pharmtox-010510-100517 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034090735
482 rdf:type schema:CreativeWork
483 https://doi.org/10.1158/0008-5472.can-05-1783 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027381088
484 rdf:type schema:CreativeWork
485 https://doi.org/10.1158/0008-5472.can-06-3307 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029555834
486 rdf:type schema:CreativeWork
487 https://doi.org/10.1158/0008-5472.can-07-1484 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033873414
488 rdf:type schema:CreativeWork
489 https://doi.org/10.1158/0008-5472.can-08-0180 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023269013
490 rdf:type schema:CreativeWork
491 https://doi.org/10.1158/0008-5472.can-08-2765 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045402097
492 rdf:type schema:CreativeWork
493 https://doi.org/10.1158/0008-5472.can-08-2920 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000717609
494 rdf:type schema:CreativeWork
495 https://doi.org/10.1158/0008-5472.can-09-2777 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021371064
496 rdf:type schema:CreativeWork
497 https://doi.org/10.1158/0008-5472.can-10-3604 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034584563
498 rdf:type schema:CreativeWork
499 https://doi.org/10.1158/1078-0432.ccr-04-2421 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038294800
500 rdf:type schema:CreativeWork
501 https://doi.org/10.1158/1078-0432.ccr-06-1109 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025893789
502 rdf:type schema:CreativeWork
503 https://doi.org/10.1158/1078-0432.ccr-09-1070 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014781757
504 rdf:type schema:CreativeWork
505 https://doi.org/10.1158/1535-7163.mct-06-0663 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009271464
506 rdf:type schema:CreativeWork
507 https://doi.org/10.1158/1535-7163.mct-07-0009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041578841
508 rdf:type schema:CreativeWork
509 https://doi.org/10.1158/1535-7163.mct-08-0021 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000376245
510 rdf:type schema:CreativeWork
511 https://doi.org/10.1158/1535-7163.mct-08-1046 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033400586
512 rdf:type schema:CreativeWork
513 https://doi.org/10.1158/1541-7786.mcr-10-0362 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047153997
514 rdf:type schema:CreativeWork
515 https://doi.org/10.1177/153303461000900109 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008289885
516 rdf:type schema:CreativeWork
517 https://doi.org/10.1182/blood-2009-09-243147 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013451101
518 rdf:type schema:CreativeWork
519 https://doi.org/10.1242/jcs.056812 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033645338
520 rdf:type schema:CreativeWork
521 https://doi.org/10.1261/rna.972008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047682260
522 rdf:type schema:CreativeWork
523 https://doi.org/10.1371/journal.pone.0001908 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021959241
524 rdf:type schema:CreativeWork
525 https://doi.org/10.1371/journal.pone.0005436 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028386927
526 rdf:type schema:CreativeWork
527 https://doi.org/10.1371/journal.pone.0006229 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015256786
528 rdf:type schema:CreativeWork
529 https://doi.org/10.1371/journal.pone.0010859 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014897599
530 rdf:type schema:CreativeWork
531 https://doi.org/10.1371/journal.pone.0013735 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051824513
532 rdf:type schema:CreativeWork
533 https://doi.org/10.1371/journal.pone.0016138 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037075915
534 rdf:type schema:CreativeWork
535 https://doi.org/10.1534/genetics.105.049791 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004941016
536 rdf:type schema:CreativeWork
537 https://doi.org/10.2147/btt.s3479 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047527339
538 rdf:type schema:CreativeWork
539 https://doi.org/10.2174/156800906777723958 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069190753
540 rdf:type schema:CreativeWork
541 https://doi.org/10.2174/156802606776173483 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069193301
542 rdf:type schema:CreativeWork
543 https://doi.org/10.3322/caac.20107 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009055747
544 rdf:type schema:CreativeWork
545 https://doi.org/10.4049/jimmunol.0904060 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018746068
546 rdf:type schema:CreativeWork
547 https://doi.org/10.4049/jimmunol.1001633 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048573458
548 rdf:type schema:CreativeWork
549 https://www.grid.ac/institutes/grid.430311.4 schema:alternateName R.E.Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology
550 schema:name Department of Mechanisms of Anticancer Therapy, R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, Kyiv, Ukraine
551 rdf:type schema:Organization
552 https://www.grid.ac/institutes/grid.483504.e schema:alternateName National Center for Toxicological Research
553 schema:name Division of Biochemical Toxicology, National Center for Toxicological Research, 3900 NCTR Rd., 72079, Jefferson, AR, USA
554 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...