Antiatherogenic and antitumoral properties of Opuntia cladodes: inhibition of low density lipoprotein oxidation by vascular cells, and protection against the ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2015-09

AUTHORS

Julia Keller, Caroline Camaré, Corinne Bernis, Marizel Astello-García, Ana-Paulina Barba de la Rosa, Michel Rossignol, María del Socorro Santos Díaz, Robert Salvayre, Anne Negre-Salvayre, Françoise Guéraud

ABSTRACT

Opuntia species have been used for thousands of years as a folk medicine in the treatment of diseases. However, the components and protective mechanisms are still unclear. We make the hypothesis that Opuntia species may protect the development of oxidative stress-associated diseases, such as atherosclerosis or colon cancer, via their antioxidant properties. We investigated the protective effect of Opuntia cladode powder against the oxidation of low-density lipoprotein (LDL) evoked by vascular endothelial cells, an important risk factor for atherosclerosis development, and the toxicity of 4-hydroxynonenal (a major lipid peroxidation product) on normal (Apc +/+) and preneoplastic (Apc min/+) immortalized epithelial colon cells. Various Opuntia species classified according to their degree of domestication, from the wildest (Opuntia streptacantha, Opuntia hyptiacantha, Opuntia megacantha), medium (Opuntia albicarpa), to the most domesticated (Opuntia ficus-indica) were tested. Cladode powders prepared from these Opuntia species significantly inhibited LDL oxidation induced by incubation with murine endothelial cells and the subsequent foam cell formation of RAW 264.7 murine macrophages and cytotoxicity on murine endothelial cells. Moreover, Opuntia cladode powder blocked the promotion of colon cancer development on an in vitro model of colonocytes. It may be noted that the phenolic acid and flavonoids content, the antioxidant capacity, and the protective effect were relatively similar in all the cladode powders from wild (O. streptacantha) and domesticated Opuntia. Altogether, these data confirm the therapeutic potential of Opuntia cladodes in diseases associated with oxidative stress. More... »

PAGES

577-587

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s13105-015-0408-x

DOI

http://dx.doi.org/10.1007/s13105-015-0408-x

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1005083595

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/25840808


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biochemistry and Cell Biology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aldehydes", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Anticarcinogenic Agents", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Colorectal Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Endothelial Cells", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Endothelium, Vascular", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Lipid Peroxidation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Lipoproteins, LDL", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mice, Inbred C57BL", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Opuntia", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Oxidation-Reduction", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Plant Extracts", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "name": [
            "INRA Toxalim, Toulouse, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Keller", 
        "givenName": "Julia", 
        "id": "sg:person.01337223612.17", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01337223612.17"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Toulouse", 
          "id": "https://www.grid.ac/institutes/grid.11417.32", 
          "name": [
            "INSERM-UMR1048, BP84225-31432, Toulouse Cedex 4, France", 
            "University of Toulouse, Toulouse, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Camar\u00e9", 
        "givenName": "Caroline", 
        "id": "sg:person.01144303167.34", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01144303167.34"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Toulouse", 
          "id": "https://www.grid.ac/institutes/grid.11417.32", 
          "name": [
            "INSERM-UMR1048, BP84225-31432, Toulouse Cedex 4, France", 
            "University of Toulouse, Toulouse, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bernis", 
        "givenName": "Corinne", 
        "id": "sg:person.01223156775.71", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01223156775.71"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute for Scientific and Technological Research", 
          "id": "https://www.grid.ac/institutes/grid.419262.a", 
          "name": [
            "Ipicyt, San Luis Potosi, Mexico"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Astello-Garc\u00eda", 
        "givenName": "Marizel", 
        "id": "sg:person.01053625073.38", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01053625073.38"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute for Scientific and Technological Research", 
          "id": "https://www.grid.ac/institutes/grid.419262.a", 
          "name": [
            "Ipicyt, San Luis Potosi, Mexico"
          ], 
          "type": "Organization"
        }, 
        "familyName": "de la Rosa", 
        "givenName": "Ana-Paulina Barba", 
        "id": "sg:person.011601661731.59", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011601661731.59"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute of Pharmacology and Structural Biology", 
          "id": "https://www.grid.ac/institutes/grid.461904.e", 
          "name": [
            "IPBS, Toulouse, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rossignol", 
        "givenName": "Michel", 
        "id": "sg:person.01311205213.63", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01311205213.63"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Autonomous University of San Luis Potos\u00ed", 
          "id": "https://www.grid.ac/institutes/grid.412862.b", 
          "name": [
            "UASLP, San Luis Potosi, Mexico"
          ], 
          "type": "Organization"
        }, 
        "familyName": "del Socorro Santos D\u00edaz", 
        "givenName": "Mar\u00eda", 
        "id": "sg:person.015537322647.16", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015537322647.16"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Toulouse", 
          "id": "https://www.grid.ac/institutes/grid.11417.32", 
          "name": [
            "INSERM-UMR1048, BP84225-31432, Toulouse Cedex 4, France", 
            "University of Toulouse, Toulouse, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Salvayre", 
        "givenName": "Robert", 
        "id": "sg:person.0645026161.16", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0645026161.16"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Toulouse", 
          "id": "https://www.grid.ac/institutes/grid.11417.32", 
          "name": [
            "INSERM-UMR1048, BP84225-31432, Toulouse Cedex 4, France", 
            "University of Toulouse, Toulouse, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Negre-Salvayre", 
        "givenName": "Anne", 
        "id": "sg:person.01106451656.62", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01106451656.62"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "INRA Toxalim, Toulouse, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gu\u00e9raud", 
        "givenName": "Fran\u00e7oise", 
        "id": "sg:person.0630153156.73", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0630153156.73"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1186/1476-4598-2-41", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000614697", 
          "https://doi.org/10.1186/1476-4598-2-41"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1083/jcb.100.3.965", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004298192"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.phymed.2007.03.017", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010795513"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1039/c4fo00071d", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014200298"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bbrc.2014.06.029", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014205247"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1179/135100007x162257", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015287236"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.foodchem.2010.05.074", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017464369"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/0008-5472.can-14-2554", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018604359"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1038/sj.bjp.0701624", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018689197"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3390/molecules190914879", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022715378"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3390/molecules190914879", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022715378"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11130-010-0189-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024565953", 
          "https://doi.org/10.1007/s11130-010-0189-x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11130-010-0189-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024565953", 
          "https://doi.org/10.1007/s11130-010-0189-x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.fct.2008.12.031", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024751149"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/cdd.2013.138", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028511037", 
          "https://doi.org/10.1038/cdd.2013.138"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0005-2760(98)00127-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029889175"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/carcin/bgl127", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030884635"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/mnfr.200500080", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031765831"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/mnfr.200500080", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031765831"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-94-007-7920-4_9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034970869", 
          "https://doi.org/10.1007/978-94-007-7920-4_9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.atv.0000097769.47306.12", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035862603"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.atv.0000097769.47306.12", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035862603"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3390/antiox2020037", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037721638"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1207/s15327914nc4501_10", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038906787"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10557-011-6326-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040469215", 
          "https://doi.org/10.1007/s10557-011-6326-4"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00041433-199710000-00005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040619181"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00041433-199710000-00005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040619181"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3109/10715762.2010.498478", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040798137"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/10715760410001728415", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041687021"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11130-009-0117-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043171615", 
          "https://doi.org/10.1007/s11130-009-0117-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11130-009-0117-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043171615", 
          "https://doi.org/10.1007/s11130-009-0117-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/mnfr.200400071", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044716354"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.274.37.25959", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045788154"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.fct.2008.01.023", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047387589"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.freeradbiomed.2008.08.026", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047656768"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jfca.2009.12.003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052965173"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/jf051960d", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055904308"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/jf051960d", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055904308"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/jf0611668", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055905315"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/jf0611668", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055905315"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/ars.2008.2403", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059230965"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/ars.2010.3321", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059231281"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/jmf.2013.3096", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059283340"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2174/138161211795049831", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1069167589"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079011670", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2015-09", 
    "datePublishedReg": "2015-09-01", 
    "description": "Opuntia species have been used for thousands of years as a folk medicine in the treatment of diseases. However, the components and protective mechanisms are still unclear. We make the hypothesis that Opuntia species may protect the development of oxidative stress-associated diseases, such as atherosclerosis or colon cancer, via their antioxidant properties. We investigated the protective effect of Opuntia cladode powder against the oxidation of low-density lipoprotein (LDL) evoked by vascular endothelial cells, an important risk factor for atherosclerosis development, and the toxicity of 4-hydroxynonenal (a major lipid peroxidation product) on normal (Apc +/+) and preneoplastic (Apc min/+) immortalized epithelial colon cells. Various Opuntia species classified according to their degree of domestication, from the wildest (Opuntia streptacantha, Opuntia hyptiacantha, Opuntia megacantha), medium (Opuntia albicarpa), to the most domesticated (Opuntia ficus-indica) were tested. Cladode powders prepared from these Opuntia species significantly inhibited LDL oxidation induced by incubation with murine endothelial cells and the subsequent foam cell formation of RAW 264.7 murine macrophages and cytotoxicity on murine endothelial cells. Moreover, Opuntia cladode powder blocked the promotion of colon cancer development on an in vitro model of colonocytes. It may be noted that the phenolic acid and flavonoids content, the antioxidant capacity, and the protective effect were relatively similar in all the cladode powders from wild (O. streptacantha) and domesticated Opuntia. Altogether, these data confirm the therapeutic potential of Opuntia cladodes in diseases associated with oxidative stress. ", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s13105-015-0408-x", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1018705", 
        "issn": [
          "1138-7548", 
          "1877-8755"
        ], 
        "name": "Journal of Physiology and Biochemistry", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "3", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "71"
      }
    ], 
    "name": "Antiatherogenic and antitumoral properties of Opuntia cladodes: inhibition of low density lipoprotein oxidation by vascular cells, and protection against the cytotoxicity of lipid oxidation product 4-hydroxynonenal in a colorectal cancer cellular model", 
    "pagination": "577-587", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "1838af1fbc141687f7c4d2b27cb2b0c46ce2bf0787d2794e38785826e62e9dd2"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "25840808"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "9812509"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s13105-015-0408-x"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1005083595"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s13105-015-0408-x", 
      "https://app.dimensions.ai/details/publication/pub.1005083595"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T02:07", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8700_00000520.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007%2Fs13105-015-0408-x"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s13105-015-0408-x'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s13105-015-0408-x'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s13105-015-0408-x'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s13105-015-0408-x'


 

This table displays all metadata directly associated to this object as RDF triples.

310 TRIPLES      21 PREDICATES      78 URIs      33 LITERALS      21 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s13105-015-0408-x schema:about N0041565a7bae46308177afc86831a582
2 N294e7b575d554e79a8d7b8be0af1046f
3 N29cecb09836a4f37b92d9721c2e0a651
4 N35f66f70aaa244f29fad70be6b5ee728
5 N3f0aaf0f04a449d582946a3f662f4498
6 N95c552d311404ae5848fe9fe842ff67a
7 Nac664a34c1a64509b2768e4f4d9ca8b2
8 Nc4299b0c94e045cb8e7f9d858a16912d
9 Nd53889a47a0f424b88cacb61203f64ca
10 Nf1975281879642c283dab14e91c373c1
11 Nf2a3b1e51a6e44f58c7a0c994db7b976
12 Nf48c5a43565747bf83f34fb386fc1627
13 anzsrc-for:06
14 anzsrc-for:0601
15 schema:author N6fc877f80c6848d7bcedceb738ddc034
16 schema:citation sg:pub.10.1007/978-94-007-7920-4_9
17 sg:pub.10.1007/s10557-011-6326-4
18 sg:pub.10.1007/s11130-009-0117-0
19 sg:pub.10.1007/s11130-010-0189-x
20 sg:pub.10.1038/cdd.2013.138
21 sg:pub.10.1186/1476-4598-2-41
22 https://app.dimensions.ai/details/publication/pub.1079011670
23 https://doi.org/10.1002/mnfr.200400071
24 https://doi.org/10.1002/mnfr.200500080
25 https://doi.org/10.1016/j.bbrc.2014.06.029
26 https://doi.org/10.1016/j.fct.2008.01.023
27 https://doi.org/10.1016/j.fct.2008.12.031
28 https://doi.org/10.1016/j.foodchem.2010.05.074
29 https://doi.org/10.1016/j.freeradbiomed.2008.08.026
30 https://doi.org/10.1016/j.jfca.2009.12.003
31 https://doi.org/10.1016/j.phymed.2007.03.017
32 https://doi.org/10.1016/s0005-2760(98)00127-1
33 https://doi.org/10.1021/jf051960d
34 https://doi.org/10.1021/jf0611668
35 https://doi.org/10.1038/sj.bjp.0701624
36 https://doi.org/10.1039/c4fo00071d
37 https://doi.org/10.1074/jbc.274.37.25959
38 https://doi.org/10.1080/10715760410001728415
39 https://doi.org/10.1083/jcb.100.3.965
40 https://doi.org/10.1089/ars.2008.2403
41 https://doi.org/10.1089/ars.2010.3321
42 https://doi.org/10.1089/jmf.2013.3096
43 https://doi.org/10.1093/carcin/bgl127
44 https://doi.org/10.1097/00041433-199710000-00005
45 https://doi.org/10.1158/0008-5472.can-14-2554
46 https://doi.org/10.1161/01.atv.0000097769.47306.12
47 https://doi.org/10.1179/135100007x162257
48 https://doi.org/10.1207/s15327914nc4501_10
49 https://doi.org/10.2174/138161211795049831
50 https://doi.org/10.3109/10715762.2010.498478
51 https://doi.org/10.3390/antiox2020037
52 https://doi.org/10.3390/molecules190914879
53 schema:datePublished 2015-09
54 schema:datePublishedReg 2015-09-01
55 schema:description Opuntia species have been used for thousands of years as a folk medicine in the treatment of diseases. However, the components and protective mechanisms are still unclear. We make the hypothesis that Opuntia species may protect the development of oxidative stress-associated diseases, such as atherosclerosis or colon cancer, via their antioxidant properties. We investigated the protective effect of Opuntia cladode powder against the oxidation of low-density lipoprotein (LDL) evoked by vascular endothelial cells, an important risk factor for atherosclerosis development, and the toxicity of 4-hydroxynonenal (a major lipid peroxidation product) on normal (Apc +/+) and preneoplastic (Apc min/+) immortalized epithelial colon cells. Various Opuntia species classified according to their degree of domestication, from the wildest (Opuntia streptacantha, Opuntia hyptiacantha, Opuntia megacantha), medium (Opuntia albicarpa), to the most domesticated (Opuntia ficus-indica) were tested. Cladode powders prepared from these Opuntia species significantly inhibited LDL oxidation induced by incubation with murine endothelial cells and the subsequent foam cell formation of RAW 264.7 murine macrophages and cytotoxicity on murine endothelial cells. Moreover, Opuntia cladode powder blocked the promotion of colon cancer development on an in vitro model of colonocytes. It may be noted that the phenolic acid and flavonoids content, the antioxidant capacity, and the protective effect were relatively similar in all the cladode powders from wild (O. streptacantha) and domesticated Opuntia. Altogether, these data confirm the therapeutic potential of Opuntia cladodes in diseases associated with oxidative stress.
56 schema:genre research_article
57 schema:inLanguage en
58 schema:isAccessibleForFree false
59 schema:isPartOf N2cd5eb8f7e5344cb9781c82a8aa12684
60 N5bbc62ebec564413aa131d51618d4725
61 sg:journal.1018705
62 schema:name Antiatherogenic and antitumoral properties of Opuntia cladodes: inhibition of low density lipoprotein oxidation by vascular cells, and protection against the cytotoxicity of lipid oxidation product 4-hydroxynonenal in a colorectal cancer cellular model
63 schema:pagination 577-587
64 schema:productId N37c0c0811e594648a46332e06c634ff8
65 N393942280bf34a76bf78665fb2daec9f
66 N473ff144c464415ab429adee2be1021b
67 N476ccf3446db46468bb22422cbb274ec
68 N9a0c8839329848208e3e91de38800d86
69 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005083595
70 https://doi.org/10.1007/s13105-015-0408-x
71 schema:sdDatePublished 2019-04-11T02:07
72 schema:sdLicense https://scigraph.springernature.com/explorer/license/
73 schema:sdPublisher N49f5ac04bd044166873e52bdb0477edf
74 schema:url http://link.springer.com/10.1007%2Fs13105-015-0408-x
75 sgo:license sg:explorer/license/
76 sgo:sdDataset articles
77 rdf:type schema:ScholarlyArticle
78 N0041565a7bae46308177afc86831a582 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
79 schema:name Plant Extracts
80 rdf:type schema:DefinedTerm
81 N13579b390b84434e89fa844786803e9e rdf:first sg:person.01106451656.62
82 rdf:rest N234712c6de124dc2864d260a02b7af08
83 N21e508c88e9e4014a6b9dd7c9a9b6b9a rdf:first sg:person.0645026161.16
84 rdf:rest N13579b390b84434e89fa844786803e9e
85 N234712c6de124dc2864d260a02b7af08 rdf:first sg:person.0630153156.73
86 rdf:rest rdf:nil
87 N23df1652d9e6421caaafe08db8abbff8 rdf:first sg:person.01144303167.34
88 rdf:rest N8ac1c55abcd1400284bc796a2eda36fd
89 N294e7b575d554e79a8d7b8be0af1046f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
90 schema:name Aldehydes
91 rdf:type schema:DefinedTerm
92 N29cecb09836a4f37b92d9721c2e0a651 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
93 schema:name Mice, Inbred C57BL
94 rdf:type schema:DefinedTerm
95 N2cd5eb8f7e5344cb9781c82a8aa12684 schema:issueNumber 3
96 rdf:type schema:PublicationIssue
97 N35f66f70aaa244f29fad70be6b5ee728 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
98 schema:name Anticarcinogenic Agents
99 rdf:type schema:DefinedTerm
100 N37c0c0811e594648a46332e06c634ff8 schema:name readcube_id
101 schema:value 1838af1fbc141687f7c4d2b27cb2b0c46ce2bf0787d2794e38785826e62e9dd2
102 rdf:type schema:PropertyValue
103 N393942280bf34a76bf78665fb2daec9f schema:name nlm_unique_id
104 schema:value 9812509
105 rdf:type schema:PropertyValue
106 N3f0aaf0f04a449d582946a3f662f4498 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
107 schema:name Colorectal Neoplasms
108 rdf:type schema:DefinedTerm
109 N41154ae9f96144db90d91d5d8d3b0ec9 rdf:first sg:person.01311205213.63
110 rdf:rest Nebe40774d1fc4f97a112f7200873f9ee
111 N473ff144c464415ab429adee2be1021b schema:name pubmed_id
112 schema:value 25840808
113 rdf:type schema:PropertyValue
114 N476ccf3446db46468bb22422cbb274ec schema:name dimensions_id
115 schema:value pub.1005083595
116 rdf:type schema:PropertyValue
117 N49f5ac04bd044166873e52bdb0477edf schema:name Springer Nature - SN SciGraph project
118 rdf:type schema:Organization
119 N560d51b274f44dc1a59e5f53039798eb rdf:first sg:person.011601661731.59
120 rdf:rest N41154ae9f96144db90d91d5d8d3b0ec9
121 N5bbc62ebec564413aa131d51618d4725 schema:volumeNumber 71
122 rdf:type schema:PublicationVolume
123 N5d48b4cc7e644833872d9536b6aa2edd schema:name INRA Toxalim, Toulouse, France
124 rdf:type schema:Organization
125 N6fc877f80c6848d7bcedceb738ddc034 rdf:first sg:person.01337223612.17
126 rdf:rest N23df1652d9e6421caaafe08db8abbff8
127 N870f5e848b6c480e8c8867e570e3795b schema:name INRA Toxalim, Toulouse, France
128 rdf:type schema:Organization
129 N8ac1c55abcd1400284bc796a2eda36fd rdf:first sg:person.01223156775.71
130 rdf:rest N9b96af50e37d440d84ab1278ad73c750
131 N95c552d311404ae5848fe9fe842ff67a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
132 schema:name Lipoproteins, LDL
133 rdf:type schema:DefinedTerm
134 N9a0c8839329848208e3e91de38800d86 schema:name doi
135 schema:value 10.1007/s13105-015-0408-x
136 rdf:type schema:PropertyValue
137 N9b96af50e37d440d84ab1278ad73c750 rdf:first sg:person.01053625073.38
138 rdf:rest N560d51b274f44dc1a59e5f53039798eb
139 Nac664a34c1a64509b2768e4f4d9ca8b2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
140 schema:name Oxidation-Reduction
141 rdf:type schema:DefinedTerm
142 Nc4299b0c94e045cb8e7f9d858a16912d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
143 schema:name Opuntia
144 rdf:type schema:DefinedTerm
145 Nd53889a47a0f424b88cacb61203f64ca schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
146 schema:name Animals
147 rdf:type schema:DefinedTerm
148 Nebe40774d1fc4f97a112f7200873f9ee rdf:first sg:person.015537322647.16
149 rdf:rest N21e508c88e9e4014a6b9dd7c9a9b6b9a
150 Nf1975281879642c283dab14e91c373c1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
151 schema:name Endothelial Cells
152 rdf:type schema:DefinedTerm
153 Nf2a3b1e51a6e44f58c7a0c994db7b976 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
154 schema:name Lipid Peroxidation
155 rdf:type schema:DefinedTerm
156 Nf48c5a43565747bf83f34fb386fc1627 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
157 schema:name Endothelium, Vascular
158 rdf:type schema:DefinedTerm
159 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
160 schema:name Biological Sciences
161 rdf:type schema:DefinedTerm
162 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
163 schema:name Biochemistry and Cell Biology
164 rdf:type schema:DefinedTerm
165 sg:journal.1018705 schema:issn 1138-7548
166 1877-8755
167 schema:name Journal of Physiology and Biochemistry
168 rdf:type schema:Periodical
169 sg:person.01053625073.38 schema:affiliation https://www.grid.ac/institutes/grid.419262.a
170 schema:familyName Astello-García
171 schema:givenName Marizel
172 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01053625073.38
173 rdf:type schema:Person
174 sg:person.01106451656.62 schema:affiliation https://www.grid.ac/institutes/grid.11417.32
175 schema:familyName Negre-Salvayre
176 schema:givenName Anne
177 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01106451656.62
178 rdf:type schema:Person
179 sg:person.01144303167.34 schema:affiliation https://www.grid.ac/institutes/grid.11417.32
180 schema:familyName Camaré
181 schema:givenName Caroline
182 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01144303167.34
183 rdf:type schema:Person
184 sg:person.011601661731.59 schema:affiliation https://www.grid.ac/institutes/grid.419262.a
185 schema:familyName de la Rosa
186 schema:givenName Ana-Paulina Barba
187 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011601661731.59
188 rdf:type schema:Person
189 sg:person.01223156775.71 schema:affiliation https://www.grid.ac/institutes/grid.11417.32
190 schema:familyName Bernis
191 schema:givenName Corinne
192 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01223156775.71
193 rdf:type schema:Person
194 sg:person.01311205213.63 schema:affiliation https://www.grid.ac/institutes/grid.461904.e
195 schema:familyName Rossignol
196 schema:givenName Michel
197 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01311205213.63
198 rdf:type schema:Person
199 sg:person.01337223612.17 schema:affiliation N870f5e848b6c480e8c8867e570e3795b
200 schema:familyName Keller
201 schema:givenName Julia
202 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01337223612.17
203 rdf:type schema:Person
204 sg:person.015537322647.16 schema:affiliation https://www.grid.ac/institutes/grid.412862.b
205 schema:familyName del Socorro Santos Díaz
206 schema:givenName María
207 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015537322647.16
208 rdf:type schema:Person
209 sg:person.0630153156.73 schema:affiliation N5d48b4cc7e644833872d9536b6aa2edd
210 schema:familyName Guéraud
211 schema:givenName Françoise
212 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0630153156.73
213 rdf:type schema:Person
214 sg:person.0645026161.16 schema:affiliation https://www.grid.ac/institutes/grid.11417.32
215 schema:familyName Salvayre
216 schema:givenName Robert
217 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0645026161.16
218 rdf:type schema:Person
219 sg:pub.10.1007/978-94-007-7920-4_9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034970869
220 https://doi.org/10.1007/978-94-007-7920-4_9
221 rdf:type schema:CreativeWork
222 sg:pub.10.1007/s10557-011-6326-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040469215
223 https://doi.org/10.1007/s10557-011-6326-4
224 rdf:type schema:CreativeWork
225 sg:pub.10.1007/s11130-009-0117-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043171615
226 https://doi.org/10.1007/s11130-009-0117-0
227 rdf:type schema:CreativeWork
228 sg:pub.10.1007/s11130-010-0189-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1024565953
229 https://doi.org/10.1007/s11130-010-0189-x
230 rdf:type schema:CreativeWork
231 sg:pub.10.1038/cdd.2013.138 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028511037
232 https://doi.org/10.1038/cdd.2013.138
233 rdf:type schema:CreativeWork
234 sg:pub.10.1186/1476-4598-2-41 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000614697
235 https://doi.org/10.1186/1476-4598-2-41
236 rdf:type schema:CreativeWork
237 https://app.dimensions.ai/details/publication/pub.1079011670 schema:CreativeWork
238 https://doi.org/10.1002/mnfr.200400071 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044716354
239 rdf:type schema:CreativeWork
240 https://doi.org/10.1002/mnfr.200500080 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031765831
241 rdf:type schema:CreativeWork
242 https://doi.org/10.1016/j.bbrc.2014.06.029 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014205247
243 rdf:type schema:CreativeWork
244 https://doi.org/10.1016/j.fct.2008.01.023 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047387589
245 rdf:type schema:CreativeWork
246 https://doi.org/10.1016/j.fct.2008.12.031 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024751149
247 rdf:type schema:CreativeWork
248 https://doi.org/10.1016/j.foodchem.2010.05.074 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017464369
249 rdf:type schema:CreativeWork
250 https://doi.org/10.1016/j.freeradbiomed.2008.08.026 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047656768
251 rdf:type schema:CreativeWork
252 https://doi.org/10.1016/j.jfca.2009.12.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052965173
253 rdf:type schema:CreativeWork
254 https://doi.org/10.1016/j.phymed.2007.03.017 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010795513
255 rdf:type schema:CreativeWork
256 https://doi.org/10.1016/s0005-2760(98)00127-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029889175
257 rdf:type schema:CreativeWork
258 https://doi.org/10.1021/jf051960d schema:sameAs https://app.dimensions.ai/details/publication/pub.1055904308
259 rdf:type schema:CreativeWork
260 https://doi.org/10.1021/jf0611668 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055905315
261 rdf:type schema:CreativeWork
262 https://doi.org/10.1038/sj.bjp.0701624 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018689197
263 rdf:type schema:CreativeWork
264 https://doi.org/10.1039/c4fo00071d schema:sameAs https://app.dimensions.ai/details/publication/pub.1014200298
265 rdf:type schema:CreativeWork
266 https://doi.org/10.1074/jbc.274.37.25959 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045788154
267 rdf:type schema:CreativeWork
268 https://doi.org/10.1080/10715760410001728415 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041687021
269 rdf:type schema:CreativeWork
270 https://doi.org/10.1083/jcb.100.3.965 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004298192
271 rdf:type schema:CreativeWork
272 https://doi.org/10.1089/ars.2008.2403 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059230965
273 rdf:type schema:CreativeWork
274 https://doi.org/10.1089/ars.2010.3321 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059231281
275 rdf:type schema:CreativeWork
276 https://doi.org/10.1089/jmf.2013.3096 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059283340
277 rdf:type schema:CreativeWork
278 https://doi.org/10.1093/carcin/bgl127 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030884635
279 rdf:type schema:CreativeWork
280 https://doi.org/10.1097/00041433-199710000-00005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040619181
281 rdf:type schema:CreativeWork
282 https://doi.org/10.1158/0008-5472.can-14-2554 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018604359
283 rdf:type schema:CreativeWork
284 https://doi.org/10.1161/01.atv.0000097769.47306.12 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035862603
285 rdf:type schema:CreativeWork
286 https://doi.org/10.1179/135100007x162257 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015287236
287 rdf:type schema:CreativeWork
288 https://doi.org/10.1207/s15327914nc4501_10 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038906787
289 rdf:type schema:CreativeWork
290 https://doi.org/10.2174/138161211795049831 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069167589
291 rdf:type schema:CreativeWork
292 https://doi.org/10.3109/10715762.2010.498478 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040798137
293 rdf:type schema:CreativeWork
294 https://doi.org/10.3390/antiox2020037 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037721638
295 rdf:type schema:CreativeWork
296 https://doi.org/10.3390/molecules190914879 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022715378
297 rdf:type schema:CreativeWork
298 https://www.grid.ac/institutes/grid.11417.32 schema:alternateName University of Toulouse
299 schema:name INSERM-UMR1048, BP84225-31432, Toulouse Cedex 4, France
300 University of Toulouse, Toulouse, France
301 rdf:type schema:Organization
302 https://www.grid.ac/institutes/grid.412862.b schema:alternateName Autonomous University of San Luis Potosí
303 schema:name UASLP, San Luis Potosi, Mexico
304 rdf:type schema:Organization
305 https://www.grid.ac/institutes/grid.419262.a schema:alternateName Institute for Scientific and Technological Research
306 schema:name Ipicyt, San Luis Potosi, Mexico
307 rdf:type schema:Organization
308 https://www.grid.ac/institutes/grid.461904.e schema:alternateName Institute of Pharmacology and Structural Biology
309 schema:name IPBS, Toulouse, France
310 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...